Hyaluronic acid based micelle for articular delivery of triamcinolone, preparation, in vitro and in vivo evaluation

International Journal of Pharmaceutics

Volumn 489, Issue 1-2, 2015, Pages 218-225

  Saadat, Ebrahim ^a   Shakor, Naeeme ^a   Gholami, Mehdi ^b   Dorkoosh, Farid A ^a,c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Articular delivery; Hyaluronic acid; In vivo real time imaging; Polymeric micelle; Triamcinolone

Indexed keywords

HYALURONIC ACID; TRIAMCINOLONE; 1,2-DISTEAROYLPHOSPHATIDYLETHANOLAMINE; ANTIINFLAMMATORY AGENT; DRUG CARRIER; MICELLE; PHOSPHATIDYLETHANOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; DEGRADATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; EMULSION; ENCAPSULATION; GIANT CELL; HISTOPATHOLOGY; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MICELLE; MICELLIZATION; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; PHASE TRANSITION; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; RAT; SUSTAINED DRUG RELEASE; SYNOVIUM; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ANATOMY AND HISTOLOGY; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECTS; DRUG FORMULATION; DRUG RELEASE; INTRAARTICULAR DRUG ADMINISTRATION; KNEE; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MICELLES; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHATIDYLETHANOLAMINES; RATS, WISTAR; TRIAMCINOLONE;

EID: 84928990717     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.05.001     Document Type: Article

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