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Volumn 8, Issue 5, 2015, Pages 429-441

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma

Author keywords

Ascl1; Cell cycle; Development; Differentiation; Neuroblastoma; Xenopus

Indexed keywords

BETA GALACTOSIDASE; CYCLIN A; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; MESSENGER RNA; MYC PROTEIN; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR SLUG; ASCL1 PROTEIN, XENOPUS; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MORPHOLINO OLIGONUCLEOTIDE; NERVE PROTEIN; XENOPUS PROTEIN; XICL PROTEIN, XENOPUS;

EID: 84928983569     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.018630     Document Type: Article
Times cited : (27)

References (53)
  • 1
    • 80052444771 scopus 로고    scopus 로고
    • Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis
    • Ali, F., Hindley, C., McDowell, G., Deibler, R., Jones, A., Kirschner, M., Guillemot, F. and Philpott, A. (2011). Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis. Development 138, 4267-4277.
    • (2011) Development , vol.138 , pp. 4267-4277
    • Ali, F.1    Hindley, C.2    McDowell, G.3    Deibler, R.4    Jones, A.5    Kirschner, M.6    Guillemot, F.7    Philpott, A.8
  • 2
    • 84901447700 scopus 로고    scopus 로고
    • The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro
    • Ali, F. R., Cheng, K., Kirwan, P., Metcalfe, S., Livesey, F. J., Barker, R. A. and Philpott, A. (2014). The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development 141, 2216-2224.
    • (2014) Development , vol.141 , pp. 2216-2224
    • Ali, F.R.1    Cheng, K.2    Kirwan, P.3    Metcalfe, S.4    Livesey, F.J.5    Barker, R.A.6    Philpott, A.7
  • 3
    • 0038279787 scopus 로고    scopus 로고
    • The protooncogene c-myc is an essential regulator of neural crest formation in xenopus
    • Bellmeyer, A., Krase, J., Lindgren, J. and LaBonne, C. (2003). The protooncogene c-myc is an essential regulator of neural crest formation in xenopus. Dev. Cell 4, 827-839.
    • (2003) Dev. Cell , vol.4 , pp. 827-839
    • Bellmeyer, A.1    Krase, J.2    Lindgren, J.3    Labonne, C.4
  • 6
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur, G. M. (2003). Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer 3, 203-216.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 9
    • 0024624407 scopus 로고
    • Proliferation and differentiation of embryonic chick sympathetic neurons: Effects of ciliary neurotrophic factor
    • Ernsberger, U., Sendtner, M. and Rohrer, H. (1989). Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor. Neuron 2, 1275-1284.
    • (1989) Neuron , vol.2 , pp. 1275-1284
    • Ernsberger, U.1    Sendtner, M.2    Rohrer, H.3
  • 10
    • 0027420712 scopus 로고
    • Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
    • Guillemot, F., Lo, L.-C., Johnson, J. E., Auerbach, A., Anderson, D. J. and Joyner, A. L. (1993). Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75, 463-476.
    • (1993) Cell , vol.75 , pp. 463-476
    • Guillemot, F.1    Lo, L.-C.2    Johnson, J.E.3    Auerbach, A.4    Anderson, D.J.5    Joyner, A.L.6
  • 11
    • 84901411259 scopus 로고    scopus 로고
    • Nervous decision-making: To divide or differentiate
    • Hardwick, L. J. A. and Philpott, A. (2014). Nervous decision-making: to divide or differentiate. Trends Genet. 30, 254-261.
    • (2014) Trends Genet. , vol.30 , pp. 254-261
    • Hardwick, L.J.A.1    Philpott, A.2
  • 12
    • 0041343108 scopus 로고    scopus 로고
    • Sox10 is required for the early development of the prospective neural crest in Xenopus embryos
    • Honoré, S. M., Aybar, M. J. and Mayor, R. (2003). Sox10 is required for the early development of the prospective neural crest in Xenopus embryos. Dev. Biol. 260, 79-96.
    • (2003) Dev. Biol. , vol.260 , pp. 79-96
    • Honoré, S.M.1    Aybar, M.J.2    Mayor, R.3
  • 13
    • 11144264102 scopus 로고    scopus 로고
    • Mechanisms and perspectives on differentiation of autonomic neurons
    • Howard, M. J. (2005). Mechanisms and perspectives on differentiation of autonomic neurons. Dev. Biol. 277, 271-286.
    • (2005) Dev. Biol. , vol.277 , pp. 271-286
    • Howard, M.J.1
  • 14
    • 0037431083 scopus 로고    scopus 로고
    • SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells
    • Kim, J., Lo, L., Dormand, E. and Anderson, D. J. (2003). SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 38, 17-31.
    • (2003) Neuron , vol.38 , pp. 17-31
    • Kim, J.1    Lo, L.2    Dormand, E.3    Anderson, D.J.4
  • 15
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler, P. S., Cheng, P. F. and Eisenman, R. N. (2002). N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16, 2699-2712.
    • (2002) Genes Dev. , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 16
    • 0034193218 scopus 로고    scopus 로고
    • Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration
    • LaBonne, C. and Bronner-Fraser, M. (2000). Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration. Dev. Biol. 221, 195-205.
    • (2000) Dev. Biol. , vol.221 , pp. 195-205
    • Labonne, C.1    Bronner-Fraser, M.2
  • 17
    • 69249213590 scopus 로고    scopus 로고
    • Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors
    • Lange, C., Huttner, W. B. and Calegari, F. (2009). Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. Cell Stem Cell 5, 320-331.
    • (2009) Cell Stem Cell , vol.5 , pp. 320-331
    • Lange, C.1    Huttner, W.B.2    Calegari, F.3
  • 18
    • 80053993502 scopus 로고    scopus 로고
    • Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis
    • Lei, J. and Howard, M. J. (2011). Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis. Development 138, 4789-4800.
    • (2011) Development , vol.138 , pp. 4789-4800
    • Lei, J.1    Howard, M.J.2
  • 19
    • 77953523121 scopus 로고    scopus 로고
    • Recent advances in neuroblastoma
    • Maris, J. M. (2010). Recent advances in neuroblastoma. N. Engl. J. Med. 362, 2202-2211.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 2202-2211
    • Maris, J.M.1
  • 21
    • 0032565767 scopus 로고    scopus 로고
    • P27Kip1: A key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line
    • Matsuo, T. and Thiele, C. J. (1998). p27Kip1: a key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line. Oncogene 16, 3337-3343.
    • (1998) Oncogene , vol.16 , pp. 3337-3343
    • Matsuo, T.1    Thiele, C.J.2
  • 22
    • 0033554684 scopus 로고    scopus 로고
    • Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group
    • Matthay, K. K., Villablanca, J. G., Seeger, R. C., Stram, D. O., Harris, R. E., Ramsay, N. K., Swift, P., Shimada, H., Black, C. T., Brodeur, G. M. et al. (1999). Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group. N. Engl. J. Med. 341, 1165-1173.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1165-1173
    • Matthay, K.K.1    Villablanca, J.G.2    Seeger, R.C.3    Stram, D.O.4    Harris, R.E.5    Ramsay, N.K.6    Swift, P.7    Shimada, H.8    Black, C.T.9    Brodeur, G.M.10
  • 27
    • 0038049378 scopus 로고    scopus 로고
    • Accumulation of p27KIP1 is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines
    • Nakamura, Y., Ozaki, T., Koseki, H., Nakagawara, A. and Sakiyama, S. (2003). Accumulation of p27KIP1 is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines. Biochem. Biophys. Res. Commun. 307, 206-213.
    • (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 206-213
    • Nakamura, Y.1    Ozaki, T.2    Koseki, H.3    Nakagawara, A.4    Sakiyama, S.5
  • 29
    • 49449087271 scopus 로고    scopus 로고
    • Xenopus zinc finger transcription factor IA1 (Insm1) expression marks anteroventral noradrenergic neuron progenitors in Xenopus embryos
    • Parlier, D., Ariza, A., Christulia, F., Genco, F., Vanhomwegen, J., Kricha, S., Souopgui, J. and Bellefroid, E. J. (2008). Xenopus zinc finger transcription factor IA1 (Insm1) expression marks anteroventral noradrenergic neuron progenitors in Xenopus embryos. Dev. Dyn. 237, 2147-2157.
    • (2008) Dev. Dyn. , vol.237 , pp. 2147-2157
    • Parlier, D.1    Ariza, A.2    Christulia, F.3    Genco, F.4    Vanhomwegen, J.5    Kricha, S.6    Souopgui, J.7    Bellefroid, E.J.8
  • 30
    • 0033609337 scopus 로고    scopus 로고
    • The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
    • Pattyn, A., Morin, X., Cremer, H., Goridis, C. and Brunet, J.-F. (1999). The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 399, 366-370.
    • (1999) Nature , vol.399 , pp. 366-370
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.-F.5
  • 34
    • 3042776331 scopus 로고    scopus 로고
    • G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus
    • Richard-Parpaillon, L., Cosgrove, R. A., Devine, C., Vernon, A. E. and Philpott, A. (2004). G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus. Development 131, 2577-2586.
    • (2004) Development , vol.131 , pp. 2577-2586
    • Richard-Parpaillon, L.1    Cosgrove, R.A.2    Devine, C.3    Vernon, A.E.4    Philpott, A.5
  • 35
    • 81855166236 scopus 로고    scopus 로고
    • Transcriptional control of differentiation and neurogenesis in autonomic ganglia
    • Rohrer, H. (2011). Transcriptional control of differentiation and neurogenesis in autonomic ganglia. Eur. J. Neurosci. 34, 1563-1573.
    • (2011) Eur. J. Neurosci. , vol.34 , pp. 1563-1573
    • Rohrer, H.1
  • 36
    • 33744547642 scopus 로고    scopus 로고
    • Perspectives on integration of cell extrinsic and cell intrinsic pathways of signaling required for differentiation of noradrenergic sympathetic ganglion neurons
    • Sarkar, A. A. and Howard, M. J. (2006). Perspectives on integration of cell extrinsic and cell intrinsic pathways of signaling required for differentiation of noradrenergic sympathetic ganglion neurons. Auton. Neurosci. 126-127, 225-231.
    • (2006) Auton. Neurosci. , vol.126-127 , pp. 225-231
    • Sarkar, A.A.1    Howard, M.J.2
  • 37
    • 0021063273 scopus 로고
    • Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
    • Schwab, M., Alitalo, K., Klempnauer, K.-H., Varmus, H. E., Bishop, J. M., Gilbert, F., Brodeur, G., Goldstein, M. and Trent, J. (1983). Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature 305, 245-248.
    • (1983) Nature , vol.305 , pp. 245-248
    • Schwab, M.1    Alitalo, K.2    Klempnauer, K.-H.3    Varmus, H.E.4    Bishop, J.M.5    Gilbert, F.6    Brodeur, G.7    Goldstein, M.8    Trent, J.9
  • 40
    • 0035204526 scopus 로고    scopus 로고
    • Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10
    • Sonnenberg-Riethmacher, E., Miehe, M., Stolt, C. C., Goerich, D. E., Wegner, M. and Riethmacher, D. (2001). Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech. Dev. 109, 253-265.
    • (2001) Mech. Dev. , vol.109 , pp. 253-265
    • Sonnenberg-Riethmacher, E.1    Miehe, M.2    Stolt, C.C.3    Goerich, D.E.4    Wegner, M.5    Riethmacher, D.6
  • 41
    • 0031984825 scopus 로고    scopus 로고
    • Sox10 mutation disrupts neural crest development in Dom Hirschsprungmo use model
    • Southard-Smith, E. M., Kos, L. and Pavan, W. J. (1998). Sox10 mutation disrupts neural crest development in Dom Hirschsprungmo use model. Nat. Genet. 18, 60-64.
    • (1998) Nat. Genet. , vol.18 , pp. 60-64
    • Southard-Smith, E.M.1    Kos, L.2    Pavan, W.J.3
  • 42
    • 3342960799 scopus 로고    scopus 로고
    • Characterization of Xenopus Phox2a and Phox2b defines expression domains within the embryonic nervous system and early heart field
    • Talikka, M., Stefani, G., Brivanlou, A. H. and Zimmerman, K. (2004). Characterization of Xenopus Phox2a and Phox2b defines expression domains within the embryonic nervous system and early heart field. Gene Expr. Patterns 4, 601-607.
    • (2004) Gene Expr. Patterns , vol.4 , pp. 601-607
    • Talikka, M.1    Stefani, G.2    Brivanlou, A.H.3    Zimmerman, K.4
  • 43
    • 0024203866 scopus 로고
    • Regulation of N-myc expression is a critical event controlling the ability of human neuroblasts to differentiate
    • Thiele, C. J. and Israel, M. A. (1988). Regulation of N-myc expression is a critical event controlling the ability of human neuroblasts to differentiate. Exp. Cell Biol. 56, 321-333.
    • (1988) Exp. Cell Biol. , vol.56 , pp. 321-333
    • Thiele, C.J.1    Israel, M.A.2
  • 44
    • 0021947043 scopus 로고
    • Decreased expression of Nmyc precedes retinoic acid-induced morphological differentiation of human neuroblastoma
    • Thiele, C. J., Reynolds, C. P. and Israel, M. A. (1985). Decreased expression of Nmyc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Nature 313, 404-406.
    • (1985) Nature , vol.313 , pp. 404-406
    • Thiele, C.J.1    Reynolds, C.P.2    Israel, M.A.3
  • 47
    • 0037207504 scopus 로고    scopus 로고
    • The cdk inhibitor p27Xic1is required for differentiation of primary neurones in Xenopus
    • Vernon, A.E., Devine, C. and Philpott, A. (2003). The cdk inhibitor p27Xic1is required for differentiation of primary neurones in Xenopus. Development 130, 85-92.
    • (2003) Development , vol.130 , pp. 85-92
    • Vernon, A.E.1    Devine, C.2    Philpott, A.3
  • 48
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen, T., Ostermeier, A., Pang, Z. P., Kokubu, Y., Südhof, T. C. and Wernig, M. (2010). Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041.
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1    Ostermeier, A.2    Pang, Z.P.3    Kokubu, Y.4    Südhof, T.C.5    Wernig, M.6
  • 50
    • 67650106548 scopus 로고    scopus 로고
    • Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysis
    • Vosper, J.M.D., McDowell, G.S., Hindley, C. J., Fiore-Heriche, C.S., Kucerova, R., Horan, I. and Philpott, A. (2009). Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysis. J. Biol. Chem. 284, 15458-15468.
    • (2009) J. Biol. Chem. , vol.284 , pp. 15458-15468
    • Vosper, J.M.D.1    McDowell, G.S.2    Hindley, C.J.3    Fiore-Heriche, C.S.4    Kucerova, R.5    Horan, I.6    Philpott, A.7
  • 51
  • 52
    • 0030999641 scopus 로고    scopus 로고
    • Targeted expression of MYCN causes neuroblastoma in transgenic mice
    • Weiss, W. A., Aldape, K., Mohapatra, G., Feuerstein, B. G. and Bishop, J. M. (1997). Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J. 16, 2985-2995.
    • (1997) EMBO J. , vol.16 , pp. 2985-2995
    • Weiss, W.A.1    Aldape, K.2    Mohapatra, G.3    Feuerstein, B.G.4    Bishop, J.M.5


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