메뉴 건너뛰기




Volumn 29, Issue 9, 2010, Pages 1394-1404

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

Author keywords

C MYC; MicroRNA; MYCN; Neuroblastoma

Indexed keywords

MESSENGER RNA; MICRORNA;

EID: 77949267058     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.429     Document Type: Article
Times cited : (108)

References (45)
  • 1
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. (2005). Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6: 635-645.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 3
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. (2009). MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 4
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. (2006). Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439: 353-357.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3    Wang, Q.4    Potti, A.5    Chasse, D.6
  • 5
    • 33845981503 scopus 로고    scopus 로고
    • Novel c-MYC target genes mediate differential effects on cell proliferation and migration
    • Cappellen D, Schlange T, Bauer M, Maurer F, Hynes NE. (2007). Novel c-MYC target genes mediate differential effects on cell proliferation and migration. EMBO Rep 8: 70-76.
    • (2007) EMBO Rep , vol.8 , pp. 70-76
    • Cappellen, D.1    Schlange, T.2    Bauer, M.3    Maurer, F.4    Hynes, N.E.5
  • 6
    • 0034090683 scopus 로고    scopus 로고
    • Expression of c-Myc and p53 correlates with clinical outcome in diffuse large B-cell lymphomas
    • Chang CC, Liu YC, Cleveland RP, Perkins SL. (2000). Expression of c-Myc and p53 correlates with clinical outcome in diffuse large B-cell lymphomas. Am J Clin Pathol 113: 512-518.
    • (2000) Am J Clin Pathol , vol.113 , pp. 512-518
    • Chang, C.C.1    Liu, Y.C.2    Cleveland, R.P.3    Perkins, S.L.4
  • 8
    • 33847009923 scopus 로고    scopus 로고
    • Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis
    • Chen Y, Stallings RL. (2007). Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis. Cancer Res 67: 976-983.
    • (2007) Cancer Res , vol.67 , pp. 976-983
    • Chen, Y.1    Stallings, R.L.2
  • 9
    • 33748302836 scopus 로고    scopus 로고
    • Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
    • Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, et al. (2006). Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38: 1060-1065.
    • (2006) Nat Genet , vol.38 , pp. 1060-1065
    • Dews, M.1    Homayouni, A.2    Yu, D.3    Murphy, D.4    Sevignani, C.5    Wentzel, E.6
  • 10
    • 48249098902 scopus 로고    scopus 로고
    • Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM
    • Fontana L, Fiori ME, Albini S, Cifaldi L, Giovinazzi S, Forloni M, et al. (2008). Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS One 3: e2236.
    • (2008) PLoS One , vol.3
    • Fontana, L.1    Fiori, M.E.2    Albini, S.3    Cifaldi, L.4    Giovinazzi, S.5    Forloni, M.6
  • 11
    • 52949154642 scopus 로고    scopus 로고
    • High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
    • Fredlund E, Ringner M, Maris JM, Pahlman S. (2008). High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma. Proc Natl Acad Sci USA 105: 14094-14099.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14094-14099
    • Fredlund, E.1    Ringner, M.2    Maris, J.M.3    Pahlman, S.4
  • 12
    • 33645505600 scopus 로고    scopus 로고
    • A new mode of transcriptional repression by c-myc: Methylation
    • Gartel AL. (2006). A new mode of transcriptional repression by c-myc: methylation. Oncogene 25: 1989-1990.
    • (2006) Oncogene , vol.25 , pp. 1989-1990
    • Gartel, A.L.1
  • 13
    • 43749104015 scopus 로고    scopus 로고
    • Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells
    • Jiang M, Zhu K, Grenet J, Lahti JM. (2008). Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim Biophys Acta 1783: 1055-1067.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1055-1067
    • Jiang, M.1    Zhu, K.2    Grenet, J.3    Lahti, J.M.4
  • 15
    • 0032211147 scopus 로고    scopus 로고
    • Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma
    • Kramer MH, Hermans J, Wijburg E, Philippo K, Geelen E, van Krieken JH, et al. (1998). Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood 92: 3152-3162.
    • (1998) Blood , vol.92 , pp. 3152-3162
    • Kramer, M.H.1    Hermans, J.2    Wijburg, E.3    Philippo, K.4    Geelen, E.5    Van Krieken, J.H.6
  • 16
    • 34250879111 scopus 로고    scopus 로고
    • Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia
    • Landais S, Landry S, Legault P, Rassart E. (2007). Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia. Cancer Res 67: 5699-5707.
    • (2007) Cancer Res , vol.67 , pp. 5699-5707
    • Landais, S.1    Landry, S.2    Legault, P.3    Rassart, E.4
  • 17
    • 52949137369 scopus 로고    scopus 로고
    • MiR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis
    • Lee Y, Samaco RC, Gatchel JR, Thaller C, Orr HT, Zoghbi HY. (2008). miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis. Nat Neurosci 11: 1137-1139.
    • (2008) Nat Neurosci , vol.11 , pp. 1137-1139
    • Lee, Y.1    Samaco, R.C.2    Gatchel, J.R.3    Thaller, C.4    Orr, H.T.5    Zoghbi, H.Y.6
  • 19
    • 34548813411 scopus 로고    scopus 로고
    • Revealing signaling pathway deregulation by using gene expression signatures and regulatory motif analysis
    • Liu Y, Ringner M. (2007). Revealing signaling pathway deregulation by using gene expression signatures and regulatory motif analysis. Genome Biol 8: R77.
    • (2007) Genome Biol , vol.8
    • Liu, Y.1    Ringner, M.2
  • 20
    • 0034213414 scopus 로고    scopus 로고
    • N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
    • Malynn BA, de Alboran IM, O'Hagan RC, Bronson R, Davidson L, DePinho RA, et al. (2000). N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation. Genes Dev 14: 1390-1399.
    • (2000) Genes Dev , vol.14 , pp. 1390-1399
    • Malynn, B.A.1    De Alboran, I.M.2    O'Hagan, R.C.3    Bronson, R.4    Davidson, L.5    Depinho, R.A.6
  • 21
    • 57149110022 scopus 로고    scopus 로고
    • High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
    • Mestdagh P, Feys T, Bernard N, Guenther S, Chen C, Speleman F, et al. (2008). High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Res 36: e143.
    • (2008) Nucleic Acids Res , vol.36
    • Mestdagh, P.1    Feys, T.2    Bernard, N.3    Guenther, S.4    Chen, C.5    Speleman, F.6
  • 23
    • 65249186793 scopus 로고    scopus 로고
    • The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
    • Northcott PA, Fernandez LA, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, et al. (2009). The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res 69: 3249-3255.
    • (2009) Cancer Res , vol.69 , pp. 3249-3255
    • Northcott, P.A.1    Fernandez, L.A.2    Hagan, J.P.3    Ellison, D.W.4    Grajkowska, W.5    Gillespie, Y.6
  • 25
    • 33750963337 scopus 로고    scopus 로고
    • Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification
    • Oberthuer A, Berthold F, Warnat P, Hero B, Kahlert Y, Spitz R, et al. (2006). Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification. J Clin Oncol 24: 5070-5078.
    • (2006) J Clin Oncol , vol.24 , pp. 5070-5078
    • Oberthuer, A.1    Berthold, F.2    Warnat, P.3    Hero, B.4    Kahlert, Y.5    Spitz, R.6
  • 26
    • 0035916914 scopus 로고    scopus 로고
    • Evidence that Myc isoforms transcription-ally repress caveolin-1 gene expression via an INR-dependent mechanism
    • Park DS, Razani B, Lasorella A, Schreiber-Agus N, Pestell RG, Iavarone A, et al. (2001). Evidence that Myc isoforms transcription-ally repress caveolin-1 gene expression via an INR-dependent mechanism. Biochemistry 40: 3354-3362.
    • (2001) Biochemistry , vol.40 , pp. 3354-3362
    • Park, D.S.1    Razani, B.2    Lasorella, A.3    Schreiber-Agus, N.4    Pestell, R.G.5    Iavarone, A.6
  • 27
    • 0942290419 scopus 로고    scopus 로고
    • The RET and TRKA pathways collaborate to regulate neuroblastoma differentiation
    • Peterson S, Bogenmann E. (2004). The RET and TRKA pathways collaborate to regulate neuroblastoma differentiation. Oncogene 23: 213-225.
    • (2004) Oncogene , vol.23 , pp. 213-225
    • Peterson, S.1    Bogenmann, E.2
  • 29
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, et al. (2007). MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 67: 9762-9770.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6
  • 30
    • 61349112251 scopus 로고    scopus 로고
    • MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
    • Sander S, Bullinger L, Klapproth K, Fiedler K, Kestler HA, Barth TF, et al. (2008). MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 112: 4202-4212.
    • (2008) Blood , vol.112 , pp. 4202-4212
    • Sander, S.1    Bullinger, L.2    Klapproth, K.3    Fiedler, K.4    Kestler, H.A.5    Barth, T.F.6
  • 32
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, et al. (1985). Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 313: 1111-1116.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3    Dalton, A.4    Siegel, S.E.5    Wong, K.Y.6
  • 35
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. (2005). Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 36
  • 38
    • 0028176145 scopus 로고
    • 1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines
    • Van Roy N, Laureys G, Cheng NC, Willem P, Opdenakker G, Versteeg R, et al. (1994). 1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines. Genes Chromosomes Cancer 10: 103-114.
    • (1994) Genes Chromosomes Cancer , vol.10 , pp. 103-114
    • Van Roy, N.1    Laureys, G.2    Cheng, N.C.3    Willem, P.4    Opdenakker, G.5    Versteeg, R.6
  • 39
    • 31944434940 scopus 로고    scopus 로고
    • Translocation-excision-deletion-amplifica-tion mechanism leading to nonsyntenic coamplification of MYC and ATBF1
    • Van Roy N, Vandesompele J, Menten B, Nilsson H, De Smet E, Rocchi M, et al. (2006). Translocation-excision-deletion-amplifica-tion mechanism leading to nonsyntenic coamplification of MYC and ATBF1. Genes Chromosomes Cancer 45: 107-117.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 107-117
    • Van Roy, N.1    Vandesompele, J.2    Menten, B.3    Nilsson, H.4    De Smet, E.5    Rocchi, M.6
  • 40
    • 0037461898 scopus 로고    scopus 로고
    • ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value
    • Vandesompele J, Edsjo A, De Preter K, Axelson H, Speleman F, Pahlman S. (2003). ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value. Oncogene 22: 456-460.
    • (2003) Oncogene , vol.22 , pp. 456-460
    • Vandesompele, J.1    Edsjo, A.2    De Preter, K.3    Axelson, H.4    Speleman, F.5    Pahlman, S.6
  • 42
    • 33745700217 scopus 로고    scopus 로고
    • Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number
    • Wang Q, Diskin S, Rappaport E, Attiyeh E, Mosse Y, Shue D, et al. (2006). Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Cancer Res 66: 6050-6062.
    • (2006) Cancer Res , vol.66 , pp. 6050-6062
    • Wang, Q.1    Diskin, S.2    Rappaport, E.3    Attiyeh, E.4    Mosse, Y.5    Shue, D.6
  • 43
    • 33750460197 scopus 로고    scopus 로고
    • Developing gene expression signatures of pathway deregulation in tumors
    • Watters JW, Roberts CJ. (2006). Developing gene expression signatures of pathway deregulation in tumors. Mol Cancer Ther 5: 2444-2449.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2444-2449
    • Watters, J.W.1    Roberts, C.J.2
  • 44
    • 55649123695 scopus 로고    scopus 로고
    • Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
    • Westermann F, Muth D, Benner A, Bauer T, Henrich KO, Oberthuer A, et al. (2008). Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 9: R150.
    • (2008) Genome Biol , vol.9
    • Westermann, F.1    Muth, D.2    Benner, A.3    Bauer, T.4    Henrich, K.O.5    Oberthuer, A.6
  • 45
    • 0842278571 scopus 로고    scopus 로고
    • An integrated database of genes responsive to the Myc oncogenic transcription factor: Identification of direct genomic targets
    • Zeller KI, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV. (2003). An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol 4: R69.
    • (2003) Genome Biol , vol.4
    • Zeller, K.I.1    Jegga, A.G.2    Aronow, B.J.3    O'Donnell, K.A.4    Dang, C.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.