In vivo biodistribution studies and cell tracking in stroke using SPECT imaging

Cell-Based Therapies in Stroke

Volumn , Issue , 2013, Pages 137-149

  Raki, Mari ^a   Bergström, Kim ^a   Jolkkonen, Jukka ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84928955966     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-7091-1175-8_10     Document Type: Chapter

References (45)

1. Acton PD, Zhou R (2005) Imaging reporter genes for cell tracking with PET and SPECT. Q J Nucl Med Mol Imaging 49:349-360
2. Anger HO (1958) Scintillation camera. Rev Sci Instrum 29:27-33
3. Barbash IM, Chouraqui P, Baron J, Feinberg MS, Etzion S, Tessone A, Miller L, Guetta E, Zipori D, Kedes LH, Kloner RA, Leor J (2003) Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 108:863-868
4. Barbosa da Fonseca LM, Gutfilen B, Rosado de Castro PH, Battistella V, Goldenberg RC, Kasai- Brunswick T, Chagas CL, Wajnberg E, Maiolino A, Salles Xavier S, Andre C, Mendez-Otero R, de Freitas GR (2010) Migration and homing of bone-marrow mononuclear cells in chronic ischemic stroke after intra-arterial injection. Exp Neurol 221:122-128
5. Beekman FJ, van der Have F, Vastenhouw B, van der Linden AJ, van Rijk PP, Burbach JP, Smidt MP (2005) U-SPECT-I: a novel system for submillimeter-resolution tomography with radiolabeled molecules in mice. J Nucl Med 46:1194-1200
6. Bindslev L, Haack-Sørensen M, Bisgaard K, Kragh L, Mortensen S, Hesse B, Kjaer A, Kastrup J (2006) Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation. Eur J Nucl Med Mol Imaging 33:1171-1177
7. Bustamante J, Dock L, Vahter M, Fowler B, Orrenius S (1997) The semiconductor elements arsenic and indium induce apoptosis in rat thymocytes. Toxicology 118:129-136
8. Caveliers V, De Keulenaer G, Everaert H, Van Riet I, Van Camp G, Verheye S, Roland J, Schoors D, Franken PR, Schots R (2007) In vivo visualization of 111In labeled CD133+ peripheral blood stem cells after intracoronary administration in patients with chronic ischemic heart disease. Q J Nucl Med Mol Imaging 51:61-66
9. Cherry SR (2006) Multimodality in vivo imaging systems: twice the power or double the trouble? Annu Rev Biomed Eng 8:35-62
10. Cherry SR, Louie AY, Jacobs RE (2008) The integration of positron emission tomography with magnetic resonance imaging. Proc IEEE 96:416-438
11. Cho JY, Shen DH, Yang W, Williams B, Buckwalter TL, La Perle KM, Hinkle G, Pozderac R Kloos R, Nagaraja HN, Barth RF, Jhiang SM (2002) In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas. Gene Ther 9:1139-1145
12. Chua JY, Pendharkar AV, Wang N, Choi R, Andres RH, Gaeta X, Zhang J, Moseley ME, Guzman R (2011) Intra-arterial injection of neural stem cells using a microneedle technique does not cause microembolic strokes. J Cereb Blood Flow Metab 31:1263-1271
13. Correa PL, Mesquita CT, Felix RM, Azevedo JC, Barbirato GB, Falcão CH, Gonzalez C, Mendonça ML, Manfrim A, de Freitas G, Oliveira CC, Silva D, Avila D, Borojevic R, Alves S, Oliveira AC Jr, Dohmann HF (2007) Assessment of intra-arterial injected autologous bone marrow mononuclear cell distribution by radioactive labeling in acute ischemic stroke. Clin Nucl Med 32:839-841
14. Dempsey MF, Wyper D, Owens J, Pimlott S, Papanastassiou V, Patterson J, Hadley DM, Nicol A Rampling R, Brown SM (2006) Assessment of 123I-FIAU imaging of herpes simplex viral gene expression in the treatment of glioma. Nucl Med Commun 27:611-617
15. Detante O, Moisan A, Dimastromatteo J, Richard MJ, Riou L, Grillon E, Barbier E, Desruet MD De Fraipont F, Segebarth C, Jaillard A, Hommel M, Ghezzi C, Remy C (2009) Intravenous administration of 99mTc-HMPAO-labeled human mesenchymal stem cells after stroke: in vivo imaging and biodistribution. Cell Transplant 18:1369-1379
16. Dewanjee MK, Rao SA, Didisheim P (1981) Indium-111 tropolone, a new high-affinity platelet label: preparation and evaluation of labeling parameters. J Nucl Med 22:981-987
17. Dwyer RM, Ryan J, Havelin RJ, Morris JC, Miller BW, Liu Z, Flavin R, O’Flatharta C, Foley MJ Barrett HH, Murphy JM, Barry FP, O’Brien T, Kerin MJ (2011) Mesenchymal stem cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer. Stem Cells 29:1149-1157
18. Franc BL, Acton PD, Mari C, Hasegawa BH (2008) Small-animal SPECT and SPECT/CT: important tools for preclinical investigation. J Nucl Med 49:1651-1663
19. Furenlid LR, Wilson DW, Chen Y-c, Kim H, Pietraski PJ, Crawford MJ, Barrett HH (2004) FastSPECT II: a second-generation high-resolution dynamic SPECT imager. IEEE Trans Nucl Sci 51:631-635
20. Gao J, Dennis JE, Muzic RF, Lundberg M, Caplan AI (2001) The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 169:12-20
21. Gera A, Steinberg GK, Guzman R (2010) In vivo neural stem cell imaging: current modalities and future directions. Regen Med 5:73-86
22. Gholamrezanezhad A, Mirpour S, Ardekani JM, Bagheri M, Alimoghadam K, Yarmand S Malekzadeh R (2009) Cytotoxicity of 111In-oxine on mesenchymal stem cells: a time-dependent adverse effect. Nucl Med Commun 30:210-216
23. Gildehaus FJ, Haasters F, Drosse I, Wagner E, Zach C, Mutschler W, Cumming P, Bartenstein P Schieker M (2011) Impact of indium-111 oxine labelling on viability of human mesenchymal stem cells in vitro, and 3D cell-tracking using SPECT/CT in vivo. Mol Imaging Biol 13:1204-1214
24. Jin Y, Kong H, Stodilka RZ, Wells RG, Zabel P, Merrifield PA, Sykes J, Prato FS (2005) Determining the minimum number of detectable cardiac-transplanted 111In-tropolone-labelled bone-marrow-derived mesenchymal stem cells by SPECT. Phys Med Biol 50:4445-4455
25. Kastis GA, Furenlid LR, Wilson DW, Peterson TE, Barber HB, Barrett HH (2004) Compact CT/SPECT small-animal imaging system. IEEE Trans Nucl Sci 51:63-67
26. Khalil MM, Tremoleda JL, Bayomy TB, Gsell W (2011) Molecular SPECT imaging: an overview. Int J Mol Imaging 2011:796025 [In press]
27. Koba W, Kim K, Lipton ML, Jelicks L, Das B, Herbst L, Fine E (2011) Imaging devices for use in small animals. Semin Nucl Med 41:151-165
28. Kraitchman DL, Tatsumi M, Gilson WD, Ishimori T, Kedziorek D, Walczak P, Segars WP, Chen HH, Fritzges D, Izbudak I, Young RG, Marcelino M, Pittenger MF, Solaiyappan M, Boston RC, Tsui BM, Wahl RL, Bulte JW (2005) Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 112:1451-1461
29. Lappalainen R, Narkilahti S, Huhtala T, Liimatainen T, Suuronen T, Närvänen A, Suuronen R Hovatta O, Jolkkonen J (2008) SPECT imaging shows accumulation of stem cells into internal organs after systemic administration in middle cerebral artery occlusion rats. Neurosci Lett 440:246-250
30. Li L, Jiang Q, Ding G, Zhang L, Zhang ZG, Li Q, Panda S, Lu M, Ewing JR, Chopp M (2010) Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study. J Cereb Blood Flow Metab 30:653-662
31. Mäkinen S, Kekarainen T, Nystedt J, Liimatainen T, Huhtala T, Närvänen A, Laine J, Jolkkonen J (2006) Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats. Brain Res 1123:207-215
32. McAfee JG, Subramanian G, Gagne G (1984) Technique of leukocyte harvesting and labeling: problems and perspectives. Semin Nucl Med 14:83-106
33. McColgan P, Sharma P, Bentley P (2011) Stem cell tracking in human trials: a meta-regression. Stem Cell Rev 7:1031-1040
34. Meikle SR, Kench P, Weisenberger AG, Wojcik R, Smith MF, Majewski S, Eberl S, Fulton RR Rosenfeld AB, Fulham MJ (2002) A prototype coded aperture detector for small animal SPECT. IEEE Trans Nucl Sci 49:2167-2171
35. Mitkari B, Kerkelä E, Nystedt J, Korhonen M, Huhtala T, Jolkkonen J (2012) Toward a more effective intracascular cell therapy in stroke. In: Balestrino M (ed) Advances in the treatment of ischemic stroke. InTech, Rijeka, pp 141-160
36. Park BN, Shim W, Lee G, Bang OY, An YS, Yoon JK, Ahn YH (2011) Early distribution of intravenously injected mesenchymal stem cells in rats with acute brain trauma evaluated by (99m) Tc-HMPAO labeling. Nucl Med Biol 38:1175-1182
37. Rowland DJ, Cherry SR (2008) Small-animal preclinical nuclear medicine instrumentation and methodology. Semin Nucl Med 38:209-222
38. Schramm NU, Ebel G, Engeland U, Schurrat T, Behe M, Behr TM (2003) High-resolution SPECT using multipinhole collimation. IEEE Trans Nucl Sci 50:315-320
39. Sharif-Paghaleh E, Sunassee K, Tavare R, Ratnasothy K, Koers A, Ali N, Alhabbab R, Blower PJ Lechler RI, Smyth LA, Mullen GE, Lombardi G (2011) In vivo SPECT reporter gene imaging of regulatory T cells. PLoS One 6:e25857
40. Smith MF, Meikle SR, Majewski S, Weisenberger AG (2003) Design of multipinhole collimators for small animal SPECT. IEEE Nucl Sci Conf Rec 4:2291-2295
41. Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, Beattie B, Koutcher J, Larson S Blasberg RG (1996) Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res 56:4087-4095
42. Walczak P, Zhang J, Gilad AA, Kedziorek DA, Ruiz-Cabelo J, Young RG, Pittenger MF, van Zijl PCM, Huang J, Bulte JWM (2008) Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke 39:1569-1574
43. Weisenberger AG, Wojcik R, Bradley EL, Brewer P, Majewski S, Qian J, Ranck A, Saha MS Smith K, Smith MF, Welsh RE (2003) SPECT-CT system for small animal imaging. IEEE Trans Nucl Sci 50:74-79
44. Weissleder R, Mahmood U (2001) Molecular imaging. Radiology 219:316-333
45. Yoon JK, Park BN, Shim WY, Shin JY, Lee G, Ahn YH (2010) In vivo tracking of 111In-labeled bone marrow mesenchymal stem cells in acute brain trauma model. Nucl Med Biol 37:381-388