Cytotoxicity of 111In-oxine on mesenchymal stem cells: A time-dependent adverse effect

Nuclear Medicine Communications

Volumn 30, Issue 3, 2009, Pages 210-216

  Gholamrezanezhad, Ali ^a,d,f   Mirpour, Sahar ^a   Ardekani, Jalil Majd ^e   Bagheri, Mohammad ^b   Alimoghadam, Kamran ^c   Yarmand, Sarah ^a   Malekzadeh, Reza ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF TEHRAN   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

^e TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

111Indium oxine; Mesenchymal stem cells; Viability

Indexed keywords

8 QUINOLINOL INDIUM IN 111; 8 QUINOLINOL; 8 QUINOLINOL INDIUM; DRUG DERIVATIVE; ORGANOMETALLIC COMPOUND;

ARTICLE; CELL LABELING; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; ISOTOPE LABELING; MESENCHYMAL STEM CELL; ANIMAL; CELL COUNT; CELL SURVIVAL; CYTOLOGY; DOG; RADIATION DOSE; RADIATION EXPOSURE; RAT; TIME;

ANIMALS; CELL COUNT; CELL SURVIVAL; DOGS; HUMANS; MESENCHYMAL STEM CELLS; ORGANOMETALLIC COMPOUNDS; OXYQUINOLINE; RADIATION DOSAGE; RATS; TIME FACTORS;

EID: 61449126431     PISSN: 01433636     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNM.0b013e328318b328     Document Type: Article

References (42)

1. Love C, Opoku-Agyemang P, Tomas MB, Pugliese PV, Bhargava KK, Palestro CJ. Pulmonary activity on labeled leukocyte images: physiologic, pathologic, and imaging correlation. Radiographies 2002; 22:1385-1393.
2. Fairchild PJ, Cartland S, Nolan KF, Waldmann H. Embryonic stem cells and the challenge of transplantation tolerance. Trends Immunol 2004; 25:465-470.
3. Jordan JD, Ming GL, Song H. Adult neurogenesis as a potential therapy for neurodegenerative diseases. Discov Med 2006; 6:144-147.
4. Gangaram-Panday ST, Faas MM, de Vos P. Towards stem-cell therapy in the endocrine pancreas. Trends Mol Med 2007; 13:164-173.
5. Sachinidis A, Fleischmann BK, Kolossov E, Wartenberg M, Sauer H, Hescheler J. Cardiac specific differentiation of mouse embryonic stem cells. Cardiovasc Res 2003; 58:278-291.
6. Priddle H, Jones DR, Burridge PW, Patient R. Hematopoiesis from human embryonic stem cells: overcoming the immune barrier in stem cell therapies. Stem Cells 2006; 24:815-824.
7. Van der Bogt KE, Swijnenburg RJ, Cao F, Wu JC. Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity. Cell Cycle 2006; 5:2748-2752.
8. Lewin M, Carlesso N, Tung CH, Tang XW, Gory D, Scadden DT, Weissleder R. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 2000; 18:410-414.
9. Hill JM, Dick AJ, Raman VK, Thompson RB, Yu ZX, Hinds KA, et al. Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells. Circulation 2003; 108:1009-1014.
10. Bulte JW, Douglas T, Witwer B, Zhang SC, Strahle E, Lewis BK, et al. Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells. Nat Biotechnol 2001; 19:1141-1147.
11. Rudelius M, Daldrup-Link HE, Heinzmann U, Piontek G, Settles M, Link TM, Schlegel J. Highly efficient paramagnetic labelling of embryonic and neuronal stem cells. Eur J Nucl Med Mol Imaging 2003; 30:1038-1044.
12. Jendelová P, Herynek V, Decroos J, Glogarová K, Andersson B, Hájek M, Syková E. Imaging the fate of implanted bone marrow stromal cells labeled with superparamagnetic nanoparticles. Magn Reson Med 2003; 50:767-776.
13. Jendelové P, Herynek V, Urdzikova L, Glogarová K, Kroupová J, Andersson B, et al. Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. J Neurosci Res 2004; 76:232-243.
14. Weissleder R, Cheng HC, Bogdanova A, Bogdanov A Jr. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging 1997; 7:258-263.
15. Yeh TC, Zhang W, Ildstad ST, Ho C. Intracellular labeling of T-cells with superparamagnetic contrast agents. Magn Reson Med 1993; 30:617-625.
16. Bindslev L, Haack-Sørensen M, Bisgaard K, Kragh L, Mortensen S, Hesse B, et al. Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation. Eur J Nucl Med Mol Imaging 2006; 33:1171-1177.
17. Nowak B, Weber C, Schober A, Zeiffer U, Liehn EA, von Hundeishausen P, et al. Indium-111 oxine labelling affects the cellular integrity of haematopoietic progenitor cells. Eur J Nucl Med Mol Imaging 2007; 34:715-721.
18. Rini JN, Bhargava KK, Tronco GG, Singer C, Caprioli R, Marwin SE, et al. PET with FDG-labeled leukocytes versus scintigraphy with 111In-oxine-labeled leukocytes for detection of infection. Radiology 2006; 238:978-987.
19. Hornick CA, Anthony CT, Hughey S, Gebhardt BM, Espenan GD, Woltering EA. Progressive nuclear translocation of somatostatin analogs. J Nucl Med 2000; 41:1256-1263.
20. 111In-tropolone-labelled bone-marrow-derived mesenchymal stem cells by SPECT. Phys Med Biol 2005; 50:4445-4455.
21. Aicher A, Brenner W, Zuhayra M, Badorff C, Massoudi S, Assmus B, et al. Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation 2003; 107; 2134-2139.
22. Zhou R, Thomas DH, Qiao H, Bal HS, Choi SR, Alavi A, et al. In vivo detection of stem cells grafted in infarcted rat myocardium. J Nucl Med 2005; 46:816-822.
23. Martin RF, Bradley TR, Hodgson GS. Cytotoxicity of an 125l-labeled DNA binding compound that induces double-stranded DNA breaks. Cancer Res 1979; 39:3244-3247.
24. Arnold LJ Jr, Dagan A, Guthel J, Kaplan NO. Antineoplastic activity of poly (l-lysine) with some ascites tumor cells. Proc Natl Acad Sci U S A 1979; 76:3246-3250.
25. Krenning EP, Valkema R, Kooij PP, Breeman WA, Bakker WH, deHerder WW, et al. Scintigraphy and radionuclide therapy with [indium-111-labelled- diethyl triamine penta-acetic acid-D-Phe1]-octreotide. Ital J Gastroenterol Hepatol 1999; 31 (Suppl 2):S219-S223.
26. Fjälling M, Andersson P, Forssell-Aronsson E, Gré tarsdóttir J, Johansson V, Tisell LE, et al. Systemic radionuclide therapy using indium-111-DTPA-D-Phe1-octreotide in midgut carcinoid syndrome. J Nucl Med 1996; 37:1519-1521.
27. Ginj M, Hinni K, Tschumi S, Schulz S, Maecke HR. Trifunctional somatostatin-based derivatives designed for targeted radiotherapy using auger electron emitters. J Nucl Med 2005; 46:2097-2103.
28. Mohamadnejad M, Namiri M, Bagheri M, Hashemi SM, Ghanaati H, Zare Mehrjardi N, et al. Phase 1 human trial of autologous bone marrow-hematopoietic stem cell transplantation in patients with decompensated cirrhosis. World J Gastroenterol 2007; 13:3359-3363.
29. Meuleman N, Tondreau T, Delforge A, Dejeneffe M, Massy M, Libertalis M, et al. Human marrow mesenchymal stem cell culture: serum-free medium allows better expansion than classical alpha-MEM medium. Eur J Haematol 2006; 76:309-316.
30. Puissant B, Barreau C, Bourin P, Clavel C, Corre J, Bousquet C, et al. Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br J Haematol 2005; 129:118-129.
31. Liu HY, Yang PP, Toledo DL, Mangel WF. Modulation of cell-associated plasminogen activator activity by cocultivation of a stem cell and its tumorigenic descendant. Mol Cell Biol 1984; 4:160-165.
32. 111In-labeled CD34 + hematopoietic progenitor cells in a rat myocardial infarction model. J Nucl Med 2004; 45:512-518.
33. Ballinger JR, Gnanasegaran G. Radiolabelled leukocytes for imaging inflammation: how radiochemistry affects clinical use. Q J Nucl Med Mol Imaging 2005; 49:308-318.
34. Bustamante J, Dock L, Vahter M, Fowler B, Orrenius S. The semiconductor elements arsenic and indium induce apoptosis in rat thymocytes. Toxicology 1997; 118:129-136.
35. Botti C, Negri DR, Seregni E, Ramakrishna V, Arienti F, Maffioli L, et al. Comparison of three different methods for radiolabelling human activated T lymphocytes. Eur J Nucl Med 1997; 24:497-504.
36. Saha Gopal B. Physics and radiobiology of nuclear medicine. 2nd ed. New York: Springer-Verlag; 2001. p. 187.
37. Caveliers V, De Keulenaer G, Everaert H, Van Riet I, Van Camp G, Verheye S, et al. In vivo visualization of 111In labeled CD133+ peripheral blood stem cells after intracoronary administration in patients with chronic ischemic heart disease. Q J Nucl Med Mol Imaging 2007; 51:61-66.
38. Gao J, Dennis JE, Muzic RF, Lundberg M, Caplan Al. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 2001; 169:12-20.
39. Chin BB, Nakamoto Y, Bulte JW, Pittenger MF, Wahl R, Kraitchman DL. 111In oxine labelled mesenchymal stem cell SPECT after intravenous administration in myocardial infarction. Nucl Med Commun 2003; 24:1149-1154.
40. Marienhagen J, Hennemann B, Andreesen R, Eilles C. 111In-oxine labelling of tumour-cytotoxic macrophages generated in vitro from circulating blood monocytes: an in vitro evaluation. Nucl Med Commun 1995; 16:357-361.
41. Breeman WA, Kwekkeboom DJ, Kooij PP, Bakker WH, Hofland LJ, Visser TJ, et al. Effect of dose and specific activity on tissue distribution of indium-111-pentetreotide in rats. J Nucl Med 1995; 36:623-627.
42. Bertrand-Caix J, Freyburger G, Bordenave L, Labrouche S, Bareille R, Baquey C, et al. Functional upregulation of granulocytes labeled with technetium-99m-HMPAO and indium-111-oxinate. J Nucl Med 1996; 37:863-868.