Vascular oxidative stress: A key factor in the development of hypertension associated with ethanol consumption

Current Hypertension Reviews

Volumn 10, Issue 4, 2015, Pages 213-222

  Ceron, Carla S ^a   Marchi, Katia C ^a   Muniz, Jaqueline J ^a   Tirapelli, Carlos R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Endothelial dysfunction; Ethanol; Hypertension; Oxidative stress; Reactive oxygen species; Superoxide anion

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CALCIUM ION; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME P450 2E1; CYTOCHROME P450 REDUCTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROPEROXIDE; LIPOXYGENASE; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; OXYGEN; PEROXIREDOXIN; PROSTAGLANDIN SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOREDOXIN; XANTHINE OXIDASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOL OXIDATION; ALCOHOLISM; ANTIOXIDANT ACTIVITY; ARTICLE; BIOAVAILABILITY; BLOOD VESSEL INJURY; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CALCIUM CELL LEVEL; CARDIOVASCULAR DISEASE; ELEVATED BLOOD PRESSURE; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; HUMAN; HYPERTENSION; INFLAMMATION; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RESPIRATORY CHAIN; SYMPATHETIC TONE; TISSUE INJURY; VASCULAR REMODELING; VASOCONSTRICTION; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; DRINKING BEHAVIOR; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

ALCOHOL DRINKING; ANIMALS; ENDOTHELIUM, VASCULAR; ETHANOL; HUMANS; HYDROGEN PEROXIDE; HYPERTENSION; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84928954478     PISSN: 15734021     EISSN: 18756506     Source Type: Journal    
DOI: 10.2174/157340211004150319122736     Document Type: Article

References (103)

1. Lian C. L’alcolisme cause d’hipertension arterielle. Bull Acad Natl Med 1915; 74: 525-8.
2. Clark VA, Chapman JM, Coulson AH. Effects of various factors on systolic and diastolic blood pressure in the Los Angeles heart study. J Chronic Dis 1967; 20(8): 571-81.
3. Gyntelberg F, Meyer J. Relationship between blood pressure and physical fitness, smoking and alcohol consumption in Copenhagen males aged 40-59. Acta Med Scand 1974; 195(5): 375-80.
4. Klatsky AL, Friedman GD, Siegelaub AB, Gerard MJ. Alcohol consumption and blood pressure Kaiser-Permanente Multiphasic Health Examination data. N Engl J Med 1977; 296(21): 1194-200.
5. Dyer AR, Stamler J, Paul O, et al. Alcohol consumption, cardiovascular risk factors, and mortality in two Chicago epidemiologic studies. Circulation 1977; 56(6): 1067-74.
6. Arkwright PD, Beilin LJ, Rouse I, Armstrong BK, Vandongen R. Effects of alcohol use and other aspects of lifestyle on blood pressure levels and prevalence of hypertension in a working population. Circulation 1982; 66(1): 60-6.
7. Milon H, Froment A, Gaspard P, Guidollet J, Ripoll JP. Alcohol consumption and blood pressure in a French epidemiological study. Eur Heart J 1982; 3(Suppl C): 59-64.
8. Friedman GD, Klatsky AL, Siegelaub AB. Alcohol intake and hypertension. Ann Intern Med 1983; 98(5 Pt 2): 846-9.
9. Marchi KC, Muniz JJ, Tirapelli CR. Hypertension and chronic ethanol consumption: What do we know after a century of study? World J Cardiol 2014; 6(5): 283-94.
10. Tirapelli CR, Leone AF, Coelho EB, et al. Effect of ethanol consumption on blood pressure and rat mesenteric arterial bed, aorta and carotid responsiveness. J Pharm Pharmacol 2007; 59(7): 985-93.
11. Utkan T, Yildiz F, Ilbay G, et al. Blood pressure and vascular reactivity to endothelin-1, phenylephrine, serotonin, KCl and acetylcholine following chronic alcohol consumption in vitro. Fundam Clin Pharmacol 2001; 15(3): 157-65.
12. Rocha JT, Hipolito UV, Martins-Oliveira A, et al. Ethanol consumption alters the expression and reactivity of adrenomedullin in the rat mesenteric arterial bed. Alcohol Alcohol 2012; 47(1): 9-17.
13. Touyz RM, Briones AM. Reactive oxygen species and vascular biology: implications in human hypertension. Hypertens Res 2011; 34(1): 5-14.
14. Mathews JD. Alcohol usage as a possible explanation for socioeconomic and occupational differentials in mortality from hypertension and coronary heart disease in England and Wales. Aust N Z J Med 1976; 6(5): 393-7.
15. MacMahon SW, Blacket RB, Macdonald GJ, Hall W. Obesity, alcohol consumption and blood pressure in Australian men and women. The National Heart Foundation of Australia Risk Factor Prevalence Study. J Hypertens 1984; 2(1): 85-91.
16. Cooke KM, Frost GW, Thornell IR, Stokes GS. Alcohol consumption and blood pressure: survey of the relationship at a health-screening clinic. Med J Aust 1982; 1(2): 65-9.
17. Klatsky AL, Friedman GD, Armstrong MA. The relationships between alcoholic beverage use and other traits to blood pressure: a new Kaiser Permanente study. Circulation 1986; 73(4): 628-36.
18. Chan TC, Sutter MC. Ethanol consumption and blood pressure. Life Sci 1983; 33(20): 1965-73.
19. Abdel-Rahman AA, Wooles WR. Ethanol-induced hypertension involves impairment of baroreceptors. Hypertension 1987; 10(1): 67-73.
20. Strickland JA, Wooles WR. Effect of acute and chronic ethanol on the agonist responses of vascular smooth muscle. Eur J Pharmacol 1988; 152(1-2): 83-91.
21. Yung LM, Leung FP, Yao X, Chen ZY, Huang Y. Reactive oxygen species in vascular wall. Cardiovasc Hematol Disord Drug Targets 2006; 6(1): 1-19.
22. Finkel T. Signal transduction by reactive oxygen species. J Cell Biol 2011; 194(1): 7-15.
23. Touyz RM. Reactive oxygen species as mediators of calcium signaling by angiotensin II: implications in vascular physiology and pathophysiology. Antioxid Redox Signal 2005; 7(9-10): 1302-14.
24. Lassegue B, San Martin A, Griendling KK. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 2012; 110(10): 1364-90.
25. Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007; 87(1): 245-313.
26. Gongora MC, Qin Z, Laude K, et al. Role of extracellular superoxide dismutase in hypertension. Hypertension 2006; 48(3): 473-81.
27. Tajima M, Kurashima Y, Sugiyama K, Ogura T, Sakagami H. The redox state of glutathione regulates the hypoxic induction of HIF-1. Eur J Pharmacol 2009; 606(1-3): 45-9.
28. Manea A. NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology. Cell Tissue Res 2010; 342(3): 325-39.
29. Zakhari S. Overview: how is alcohol metabolized by the body? Alcohol Res Health 2006; 29(4): 245-54.
30. Albano E. Alcohol, oxidative stress and free radical damage. Proc Nutr Soc 2006; 65(3): 278-90.
31. Vucevic D, Mladenovic D, Ninkovic M, et al. Influence of aging on ethanol-induced oxidative stress in digestive tract of rats. Hum Exp Toxicol 2013; 32(7): 698-705.
32. Li H, Horke S, Forstermann U. Vascular oxidative stress, nitric oxide and atherosclerosis. Atherosclerosis 2014; 237(1): 208-19.
33. Singh K, Kaur J, Ahluwalia P, Sharma J. Effect of monosodium glutamate on various lipid fractions and certain antioxidant enzymes in arterial tissue of chronic alcoholic adult male mice. Toxicol Int 2012; 19(1): 9-14.
34. Husain K. Vascular endothelial oxidative stress in alcohol-induced hypertension. Cell Mol Biol 2007; 53(1): 70-7.
35. Fahimi HD, Kino M, Hicks L, Thorp KA, Abelman WH. Increased myocardial catalase in rats fed ethanol. Am J Pathol 1979; 96(2): 373-90.
36. Dinu D, Nechifor MT, Movileanu L. Ethanol-induced alterations of the antioxidant defense system in rat kidney. J Biochem Mol Toxicol 2005; 19(6): 386-95.
37. 2 production selectively in pericentral regions of the liver lobule. Alcohol Clin Exp Res 1992; 16(5): 839-42.
38. Popolo A, Autore G, Pinto A, Marzocco S. Oxidative stress in patients with cardiovascular disease and chronic renal failure. Free Radic Res 2013; 47(5): 346-56.
39. Rua RM, Ojeda ML, Nogales F, et al. Serum selenium levels and oxidative balance as differential markers in hepatic damage caused by alcohol. Life Sci 2014; 94(2): 158-63.
40. Bhabak KP, Mugesh G. Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants. Acc Chem Res 2010; 43(11): 1408-19.
41. Rendon-Ramirez A, Cortes-Couto M, Martinez-Rizo AB, Muniz- Hernandez S, Velazquez-Fernandez JB. Oxidative damage in young alcohol drinkers: A preliminary study. Alcohol 2013; 47(7): 501-4.
42. Husain K, Mejia J, Lalla J, Kazim S. Time response of alcoholinduced alterations in blood pressure, nitric oxide and oxidant to antioxidant balance in the plasma of rats. Exp Clin Cardiol 2004; 9(4): 229-34.
43. Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 2008; 31(Suppl 2): S170-80.
44. Yeligar SM, Harris FL, Hart CM, Brown LA. Ethanol induces oxidative stress in alveolar macrophages via upregulation of NADPH oxidases. J Immunol 2012; 188(8): 3648-57.
45. Thakur V, Pritchard MT, McMullen MR, Wang Q, Nagy LE. Chronic ethanol feeding increases activation of NADPH oxidase by lipopolysaccharide in rat Kupffer cells: role of increased reactive oxygen in LPS-stimulated ERK1/2 activation and TNF-alpha production. J Leukoc Biol 2006; 79(6): 1348-56.
46. Qin L, Crews FT. NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration. J Neuroinflammation 2012; 9: 5.
47. Kono H, Rusyn I, Yin M, et al. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest 2000; 106(7): 867-72.
48. Polikandriotis JA, Rupnow HL, Elms SC, et al. Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung. Am J Respir Cell Mol Biol 2006; 34(3): 314-9.
49. Wagner MC, Yeligar SM, Brown LA, Michael Hart C. PPARgamma ligands regulate NADPH oxidase, eNOS, and barrier function in the lung following chronic alcohol ingestion. Alcohol Clin Exp Res 2012; 36(2): 197-206.
50. Husain K, Ferder L, Ansari RA, Lalla J. Chronic ethanol ingestion induces aortic inflammation/oxidative endothelial injury and hypertension in rats. Hum Exp Toxicol 2011; 30(8): 930-9.
51. Gonzalez J, Valls N, Brito R, Rodrigo R. Essential hypertension and oxidative stress: New insights. World J Cardiol 2014; 6(6): 353-66.
52. Musicki B, Liu T, Lagoda GA, et al. Hypercholesterolemiainduced erectile dysfunction: endothelial nitric oxide synthase (eNOS) uncoupling in the mouse penis by NAD(P)H oxidase. J Sex Med 2010; 7(9): 3023-32.
53. Dudzinski DM, Igarashi J, Greif D, Michel T. The regulation and pharmacology of endothelial nitric oxide synthase. Annu Rev Pharmacol Toxicol 2006; 46: 235-76.
54. Baraona E, Zeballos GA, Shoichet L, Mak KM, Lieber CS. Ethanol consumption increases nitric oxide production in rats, and its peroxynitrite-mediated toxicity is attenuated by polyenylphosphatidylcholine. Alcohol Clin Exp Res 2002; 26(6): 883-9.
55. Cigremis Y, Turkoz Y, Tuzcu M, et al. The effects of chronic exposure to ethanol and cigarette smoke on the formation of peroxynitrite, level of nitric oxide, xanthine oxidase and myeloperoxidase activities in rat kidney. Mol Cell Biochem 2006; 291(1-2): 127-38.
56. Sun H, Mayhan WG. Sex difference in nitric oxide synthasedependent dilatation of cerebral arterioles during long-term alcohol consumption. Alcohol Clin Exp Res 2005; 29(3): 430-6.
57. Sun H, Patel KP, Mayhan WG. Impairment of neuronal nitric oxide synthase-dependent dilation of cerebral arterioles during chronic alcohol consumption. Alcohol Clin Exp Res 2002; 26(5): 663-70.
58. Kalyanaraman B. Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms. Redox Biol 2013; 1(1): 244-57.
59. Aberle IN, Ren J. Experimental Assessment of the Role of Acetaldehyde in Alcoholic Cardiomyopathy. Biol Proced Online 2003; 5: 1-12.
60. Forstermann U, Sessa WC. Nitric oxide synthases: regulation and function. Eur Heart J 2012; 33(7): 829-37.37a-37d.
61. Touyz RM. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension 2004; 44(3): 248-52.
62. Suzuki H, DeLano FA, Parks DA, et al. Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Natl Acad Sci U S A 1998; 95(8): 4754-9.
63. Kato S, Kawase T, Alderman J, Inatomi N, Lieber CS. Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gastroenterology 1990; 98(1): 203-10.
64. Pinardi G, Brieva C, Vinet R, Penna M. Effects of chronic ethanol consumption on alpha-adrenergic-induced contractions in rat thoracic aorta. Gen Pharmacol 1992; 23(2): 245-8.
65. Stewart CW, Kennedy RH. Effects of chronic ethanol consumption on aortic constriction in male and female rats. Eur J Pharmacol 1999; 366(1): 55-60.
66. Hatton DC, Bukoski RD, Edgar S, McCarron DA. Chronic alcohol consumption lowers blood pressure but enhances vascular contractility in Wistar rats. J Hypertens 1992; 10(6): 529-37.
67. Ladipo CO, Adigun SA, Nwaigwe CI, Adegunloye BJ. Chronic ethanol consumption alters vascular smooth muscle responses in rats. Clin Exp Pharmacol Physiol 2002; 29(8): 707-9.
68. Vasdev S, Sampson CA, Prabhakaran VM. Platelet-free calcium and vascular calcium uptake in ethanol-induced hypertensive rats. Hypertension 1991; 18(1): 116-22.
69. 2+: relevance to fetal alcohol syndrome. Eur J Pharmacol 1996; 314(3): R9-11.
70. 2+]i: relation to etiology of alcohol-induced stroke. Alcohol 1997; 14(4): 367-71.
71. Tirapelli CR, Al-Khoury J, Bkaily G, et al. Chronic ethanol consumption enhances phenylephrine-induced contraction in the isolated rat aorta. J Pharmacol Exp Ther 2006; 316(1): 233-41.
72. Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003; 4(7): 517-29.
73. Drummond GR, Selemidis S, Griendling KK, Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov 2011; 10(6): 453-71.
74. Tabet F, Savoia C, Schiffrin EL, Touyz RM. Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats. J Cardiovasc Pharmacol 2004; 44(2): 200-8.
75. Roveri A, Coassin M, Maiorino M, et al. Effect of hydrogen peroxide on calcium homeostasis in smooth muscle cells. Arch Biochem Biophys 1992; 297(2): 265-70.
76. Trebak M, Ginnan R, Singer HA, Jourd'heuil D. Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling. Antioxid Redox 2010; 12(5): 657-74.
77. Hidalgo C, Donoso P. Crosstalk between calcium and redox signaling: from molecular mechanisms to health implications. Antioxid Redox Signal 2008; 10(7): 1275-312.
78. Ermak G, Davies KJ. Calcium and oxidative stress: from cell signaling to cell death. Mol Immunol 2002; 38(10): 713-21.
79. 2+]i in cultured canine cerebral vascular smooth muscle cells. Neurosci Lett 1998; 245(1): 17-20.
80. Li W, Zheng T, Altura BT, Altura BM. Antioxidants prevent ethanol-induced contractions of canine cerebral vascular smooth muscle: relation to alcohol-induced brain injury. Neurosci Lett 2001; 301(2): 91-4.
81. Li W, Liu W, Altura BT, Altura BM. Catalase prevents elevation of Ca(2+)](i) induced by alcohol in cultured canine cerebral vascular smooth muscle cells: Possible relationship to alcohol-induced stroke and brain pathology. Brain Res Bull. 2003; 59(4): 315-8.
82. Yogi A, Callera GE, Hipolito UV, Silva CR, Touyz RM, Tirapelli CR. Ethanol-induced vasoconstriction is mediated via redoxsensitive cyclo-oxygenase-dependent mechanisms. Clin Sci (Lond) 2010; 118(11): 657-68.
83. Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 2000; 52(4): 639-72.
84. Aroor AR, Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sci 2004; 74(19): 2339-64.
85. Sachinidis A, Gouni-Berthold I, Seul C, et al. Early intracellular signalling pathway of ethanol in vascular smooth muscle cells. Br J Pharmacol 1999; 128(8): 1761-71.
86. Yang ZW, Wang J, Zheng T, Altura BT, Altura BM. Ethanolinduced contractions in cerebral arteries: role of tyrosine and mitogen-activated protein kinases. Stroke 2001; 32(1): 249-57.
87. Yang ZW, Wang J, Zheng T, Altura BT, Altura BM. Roles of tyrosine kinase-, 1-phosphatidylinositol 3-kinase-, and mitogenactivated protein kinase-signaling pathways in ethanol-induced contractions of rat aortic smooth muscle: possible relation to alcohol-induced hypertension. Alcohol 2002; 28(1): 17-28.
88. Yogi A, Callera GE, Mecawi AS, et al. Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: a role for angiotensin type 1 receptor. Toxicol Appl Pharmacol 2012; 264(3): 470-8.
89. Gonzaga NA, Callera GE, Yogi A, et al. Acute ethanol intake induces mitogen-activated protein kinase activation, platelet-derived growth factor receptor phosphorylation, and oxidative stress in resistance arteries. J Physiol Biochem 2014; 70(2): 509-23.
90. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288(5789): 373-6.
91. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327(6122): 524-6.
92. Villanueva C, Giulivi C. Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease. Free Radic Biol Med 2010; 49(3): 307-16.
93. Vanhoutte PM. Endothelium and control of vascular function. State of the Art lecture. Hypertension 1989; 13(6 Pt 2): 658-67.
94. Brizzolara AL, Morris DG, Burnstock G. Ethanol affects sympathetic cotransmission and endothelium-dependent relaxation in the rat. Eur J Pharmacol 1994; 254(1-2): 175-81.
95. Mayhan WG. Responses of cerebral arterioles during chronic ethanol exposure. Am J Physiol 1992; 262(3 Pt 2): H787-91.
96. Mayhan WG, Didion SP. Effect of chronic alcohol consumption on responses of cerebral arterioles. Alcohol Clin Exp Res 1996; 20(3): 538-42.
97. Tirapelli CR, Leone AF, Yogi A, et al. Ethanol consumption increases blood pressure and alters the responsiveness of the mesenteric vasculature in rats. J Pharm Pharmacol 2008; 60(3): 331-41.
98. Sun H, Mayhan WG. Temporal effect of alcohol consumption on reactivity of pial arterioles: role of oxygen radicals. Am J Physiol Heart Circ Physiol 2001; 280(3): H992-H1001.
99. Sun H, Mayhan WG. Superoxide dismutase ameliorates impaired nitric oxide synthase-dependent dilatation of the basilar artery during chronic alcohol consumption. Brain Res 2001; 891(1-2): 116-22.
100. 1Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 1995; 91(1): 139-44.
101. Sun H, Molacek E, Zheng H, Fang Q, Patel KP, Mayhan WG. Alcohol-induced impairment of neuronal nitric oxide synthase (nNOS)-dependent dilation of cerebral arterioles: role of NAD(P)H oxidase. J Mol Cell Cardiol 2006; 40(2): 321-8.
102. Husain K, Vazquez M, Ansari RA, Malafa MP, Lalla J. Chronic alcohol-induced oxidative endothelial injury relates to angiotensin II levels in the rat. Mol Cell Biochem 2008; 307(1-2): 51-8.
103. Haorah J, Knipe B, Leibhart J, Ghorpade A, Persidsky Y. Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction. J Leukoc Biol 2005; 78(6): 1223-32.