Ethanol-induced vasoconstriction is mediated via redox-sensitive cyclo-oxygenase-dependent mechanisms

Clinical Science

Volumn 118, Issue 11, 2010, Pages 657-668

  Yogi, Alvaro ^a   Callera, Glaucia E ^a   Hipólito, Ulisses V ^b   Silva, Catiane R ^b   Touyz, Rhian M ^a   Tirapelli, Carlos R ^b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aorta; Calcium; Hydrogen peroxide; Prostanoid; Reactive oxygen species; Superoxide anion

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; 7 NITROINDAZOLE; ALCOHOL; CALCIUM; CATALASE; HYDROGEN PEROXIDE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; OXYGEN; OXYHEMOGLOBIN; PROSTAGLANDIN SYNTHASE; REACTIVE OXYGEN METABOLITE; TIRON; SUPEROXIDE; VERAPAMIL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENDOTHELIUM; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; ANIMAL; AORTA; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; AORTA; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ETHANOL; MALE; OXIDATION-REDUCTION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TISSUE CULTURE TECHNIQUES; VASOCONSTRICTION; VERAPAMIL;

EID: 77954064761     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20090352     Document Type: Article

References (33)

1. Tirapelli, C. R., Legros, E., Brochu, I., Honoré, J. C., Lanchote, V. L., Uyemura, S. A., de Oliveira, A. M. and D'Orléans-Juste, P. (2008) Chronic ethanol intake modulates vascular levels of endothelin-1 receptor and enhances the pressor response to endothelin-1 in anaesthetized rats. Br. J. Pharmacol. 154, 971-981
2. Tirapelli, C. R., Leone, A. F., Yogi, A., Tostes, R. C., Lanchote, V. L., Uyemura, S. A, Resstel, L. B., Corrêa, F. M., Padovan, C. M., de Oliveira, A. M. and Coelho, E. B. (2008) Ethanol consumption increases blood pressure and alters the responsiveness of the mesenteric vasculature in rats. J. Pharm. Pharmacol. 60, 331-341
3. Wakabayashi, I. (2008) Influence of gender on the association of alcohol drinking with blood pressure. Am. J. Hypertens. 21, 1310-1317
4. Altura, B. M., Altura, B. T. and Gebrewold, A. (1983) Alcohol-induced spasms of cerebral blood vessels: relation to cerebrovascular accidents and sudden death. Science 220, 331-333
5. 2+ release in ethanol-induced contraction of cerebral arterial smooth muscle. Alcohol 24, 145-153
6. Yang, Z.W., Wang, J., Zheng, T.,Altura, B. T. and Altura, B. M. (2002) Roles of tyrosine kinase-, 1-phosphatidylinositol 3-kinase-, and mitogen-activated protein kinase-signaling pathways in ethanol-induced contractions of rat aortic smooth muscle: possible relation to alcohol-induced hypertension. Alcohol 28, 17-28
7. i: relation to etiology of alcohol-induced stroke. Alcohol 14, 367-371
8. Touyz, R. M. (2000) Oxidative stress and vascular damage in hypertension. Curr. Hypertens. Rep. 2, 98-105
9. Touyz, R. M. and Schiffrin, E. L. (2004) Reactive oxygen species in vascular biology: implications in hypertension. Histochem. Cell Biol. 122, 339-352
10. Dicker, E. and Cederbaum, A. I. (1987) Hydrogen radical generation by microsomes after chronic consumption alcohol. Alcohol Clin. Exp. Res. 11, 309-314
11. Altura, B. M. and Gebrewold, A. (1996) α-Tocopherol attenuates alcohol-induced cerebral vascular damage in rats: possible role of oxidants in alcohol brain pathology and stroke. Neurosci. Lett. 220, 207-210
12. i in canine cerebral arterial smooth muscle: participation of cellular signaling pathways. Naunyn Schmiedebergs Arch. Pharmacol. 360, 646-653
13. i in cultured canine cerebral vascular smooth muscle cells. Neurosci. Lett. 245, 17-20
14. Li, W., Zheng, T., Altura, B. T. and Altura, B. M. (2001) Antioxidants prevent ethanol-induced contractions of canine cerebral vascular smooth muscle: relation to alcohol-induced brain injury. Neurosc. Lett. 301, 91-94
15. Katusić, Z. S., Schugel, J., Cosentino, F. and Vanhoutte, P. M. (1993) Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. Am. J. Physiol. 264, H859-H864
16. Rodríguez-Martínez, M. A., García-Cohen, E. C., Baena, A. B., González, R., Salaíces, M. and Marín, J. (1998) Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved. Br. J. Pharmacol. 125, 1329-1335
17. Karanian, J.W., Stojanov,M. and Salem, N. Jr. (1985) Effect of ethanol on prostacyclin and thromboxane A2 synthesis in rat aortic rings in vitro. Prostaglandins Leukot. Med. 20, 175-186
18. Altura, B. M., Altura, B. T and Carella, A. (1983b) Ethanol produces coronary vasospasm: evidence for a direct action of ethanol on vascular muscle. Br. J. Pharmacol. 78, 260-262
19. Kalant, H. (1971) Effects of ethanol on the nervous system, In: International Encyclopedia of Pharmacology and Therapeutics: Alcohols and Derivatives (Tremolleres, J., ed.), pp. 189-236, Pergamon, New York
20. Husain, K., Mejia, J., Lalla, J. and Kazim, S. (2005) Dose response of alcohol-induced change in BP, nitric oxide and antioxidants in rat plasma. Pharmacol. Res. 51, 337-343
21. Callera, G. E., Touyz, R. M., Tostes, R. C., Yogi, A., He, Y., Malkinson, S. and Schiffrin, E. L. (2005) Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Hypertension 45, 773-739
22. Altura, B. M. and Altura, B. T. (1994) Role of magnesium and calcium in alcohol-induced hypertension and strokes as probed by in-vivo television microscopy, digital image microscopy, optical spectroscopy, P-NMR spectroscopy and a unique magnesium ion-selective electrode. Alcohol Clin. Exp. Res. 18, 1057-1068
23. Zhang, A., Altura, B. T. and Altura, B. M. (1993) Ethanol-induced contraction of cerebral arteries in diverse mammals and its mechanism of action, Eur. J. Pharmacol. 248, 229-236
24. Katusic, Z. S. and Vanhoutte, P. M. (1989) Superoxide anion is an endothelium-derived contracting factor. Am. J. Physiol. 257, H33-H37
25. Lassegue, B. and Clempus, R. E. (2003) Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R277-R297
26. i in cultured canine cerebral vascular smooth muscle cells. Neurosci. Lett. 266, 205-208
27. 2 in isolated rat heart. Am. J. Physiol. 271, H2447-H2453
28. Gupte, S. A., Okada, T., Tateyama, M. and Ochi, R. (2000) Activation of TxA2/PGH2 receptors and protein kinase C contribute to coronary dysfunction in superoxide treated rat hearts J. Mol. Cell. Cardiol. 32, 937-946
29. Kontos, H. A. (1985) Oxygen radicals in cerebral vascular injury. Circ. Res. 57, 508-516
30. Coleman, R. A., Smith,W. L. and Narumiya, S. (1994) VIII International Union of Pharmacology classification of prostanoid receptors: properties, distribution and structure of the receptors and their subtypes. Pharmacol. Rev. 46, 205-224
31. Tesfamariam, B. (1994) Free radicals in diabetic endothelial cell dysfunction. Free Radical Biol. Med. 16, 383-391
32. Altura, B. M., Gebrewold, A., Zhang, A. and Altura, B. T. (2002) Ethanol induces rapid lipid peroxidation and activation of nuclear factor-κB in cerebral vascular smooth muscle: relation to alcohol-induced brain injury in rats. Neurosci. Lett. 325, 95-98
33. Klatsky, A. L., Friedman, G. D., Siegelaub, A. B. and Gérard, M. J. (1977) Alcohol consumption and blood pressure: Kaiser-Permanente Multiphasic Health Examination data. N. Engl. J. Med. 296, 1194-1200