Mitochondrial delivery of antisense RNA by MITO-Porter results inmitochondrial RNA knockdown, and has a functional impact onmitochondria

Biomaterials

Volumn 57, Issue , 2015, Pages 107-115

  Furukawa, Ryo ^a   Yamada, Yuma ^a   Kawamura, Eriko ^a   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

MITO Porter; Mitochondria; Mitochondrial drug delivery; Mitochondrial RNA knockdown; Nanotechnology; Nucleic acids delivery

Indexed keywords

C (PROGRAMMING LANGUAGE); CELL MEMBRANES; CONTROLLED DRUG DELIVERY; GENE THERAPY; GENE TRANSFER; MITOCHONDRIA; NANOTECHNOLOGY; OLIGONUCLEOTIDES; RNA;

MITO-PORTER; MITOCHONDRIAL DISEASE; MITOCHONDRIAL FUNCTION; MITOCHONDRIAL GENOMES; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATORY CHAIN; MITOCHONDRIAL RNA KNOCKDOWN; NUCLEIC ACIDS DELIVERIES;

TARGETED DRUG DELIVERY;

ANTISENSE OLIGONUCLEOTIDE; ANTISENSE RNA OLIGONUCLEOTIDE; CYTOCHROME C OXIDASE; MITOCHONDRIAL RNA; TRANSFER RNA; UNCLASSIFIED DRUG; COMPLEMENTARY RNA; CYTOCHROME C OXIDASE SUBUNIT II; MESSENGER RNA; RNA; RNA, MITOCHONDRIAL;

ANTISENSE THERAPY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE SILENCING; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MEMBRANE FUSION; MITOCHONDRIAL GENOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; GENETICS;

ELECTRON TRANSPORT COMPLEX IV; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MITOCHONDRIA; RNA; RNA, ANTISENSE; RNA, MESSENGER;

EID: 84928941549     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.04.022     Document Type: Article

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