Mutations in a tRNA import signal define distinct receptors at the two membranes of Leishmania mitochondria

Molecular and Cellular Biology

Volumn 20, Issue 19, 2000, Pages 7410-7417

  Bhattacharyya, S N ^a   Mukherjee, S ^a   Adhya, S ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE RECEPTOR; PROTOZOAL RNA; RECEPTOR ANTIBODY; TYROSINE TRANSFER RNA;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; LEISHMANIA TROPICA; MITOCHONDRIAL MEMBRANE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; RNA CONFORMATION; RNA TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMAL; BASE PAIRING; BIOLOGICAL TRANSPORT, ACTIVE; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CATIONS, MONOVALENT; COMPARATIVE STUDY; INTRACELLULAR MEMBRANES; LEISHMANIA TROPICA; MEMBRANE PROTEINS; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; NIGERICIN; NUCLEIC ACID CONFORMATION; PHENOTYPE; POINT MUTATION; PROTEIN BINDING; PROTOZOAN PROTEINS; RNA, PROTOZOAN; RNA, TRANSFER, TYR; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TEMPERATURE; UNCOUPLING AGENTS;

LEISHMANIA;

EID: 0033826322     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.19.7410-7417.2000     Document Type: Article

References (26)

1. Role of an RNA binding protein in import of tRNA into Leishmania mitochondria
2. Native and imported transfer RNA in mitochondria
3. Organization and chromosomal localization of β-tubulin genes in Leishmania donovani
4. Interaction of small ribosomal and transfer RNAs with a protein from Leishmania donovani
5. Mitochondrial evolution
6. Genome structure and gene content in protist mitochondrial DNAs
7. The mitochondrial tRNAs of Trypanosoma brucei are nuclear encoded
8. tRNAs are imported into the mitochondria of Trypanosoma brucei independent of their genomic context and of their genetic origin
9. Striking differences in mitochondrial tRNA import between different plant species
10. Sequence dependent in vivo importation of tRNAs into the mitochondrion of Leishmania tarentolae
11. Selective import of nuclear-encoded tRNAs into mitochondria of the protozoan Leishmania tarentolae
12. Import of RNA into Leishmania mitochondria occurs through direct interaction with membrane-bound receptors
13. The D arm of tRNA(Tyr) is necessary and sufficient for import into Leishmania mitochondria in vitro
14. Import of small RNAs into Leishmania mitochondria in vitro
15. Import of nuclear deoxyribonucleic acid coded lysine-accepting transfer ribonucleic acid (anticodon C-U-U) into yeast mitochondria
16. tRNAs of Trypanosoma brucei: Unusual gene organization and mitochondrial importation
17. Stepwise transfer of tRNA through the double membrane of Leishmania mitochondria
18. tRNAs and proteins are imported into mitochondria of Trypanosoma brucei by two distinct mechanisms
19. Sub-fractionation of mitochondria and isolation of the proteins of oxidative phosphorylation
20. The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena
21. A nuclear encoded tRNA of Trypanosoma brucei is imported into mitochondria
22. A nuclear tRNA gene cluster in the protozoan Leishmania tarentolae and differential distribution of nuclear-encoded tRNAs between the cytosol and mitochondria
23. Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function
24. 32P-labeled RNA: Double digestion and pancreatic ribonuclease analyses
25. In vitro import of a nuclearly encoded tRNA into the mitochondrion of Trypanosoma brucei
26. Computer prediction of RNA structure