An association analysis of Per2 with panic disorder in the Japanese population

Journal of Human Genetics

Volumn 56, Issue 10, 2011, Pages 748-750

  Otowa, Takeshi ^a   Tochigi, Mamoru ^a   Kawamura, Yoshiya ^a   Sugaya, Nagisa ^b   Yoshida, Eiji ^c   Inoue, Ken ^d   Yasuda, Shin ^c   Umekage, Tadashi ^a   Ebisawa, Takashi ^a   Tanii, Hisashi ^e   Kaiya, Hisanobu ^c,f   Okazaki, Yuji ^g   Kato, Nobumasa ^h   Sasaki, Tsukasa ⁱ  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c Akasaka Mental Clinic   (Japan)

^d FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e MIE UNIVERSITY   (Japan)

^f Nagoya Mental Clinic   (Japan)

^g TOKYO METROPOLITAN MATSUZAWA HOSPITAL   (Japan)

^h SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ UNIVERSITY OF TOKYO   (Japan)

Author keywords

case control study; Japanese population; panic disorder; Per2

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC SCREENING; GENOTYPE; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; PANIC; PATHOGENESIS; PER2 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP DISORDER;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; PANIC DISORDER; PERIOD CIRCADIAN PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 80155133615     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2011.94     Document Type: Article

References (20)

1. Eaton, W. W., Kessler, R. C., Wittchen, H. U. & Magee, W. J. Panic and panic disorder in the United States. Am. J. Psychiatry 151, 413-420 (1994).
2. Weissman, M. M., Bland, R. C., Canino, G. J., Faravelli, C., Greenwald, S., Hwu, H. G. et al. The cross-national epidemiology of panic disorder. Arch. Gen. Psychiatry 54, 305-309 (1997).
3. Crowe, R. R., Noyes, R., Pauls, D. L. & Slymen, D. A family study of panic disorder. Arch. Gen. Psychiatry 40, 1065-1069 (1983).
4. Kendler, K. S., Neale, M. C., Kessler, R. C., Heath, A. C. & Eaves, L. J. Panic disorder in women, a population-based twin study. Psychol. Med. 23, 397-406 (1993).
5. Hettema, J. M., Neale, M. C. & Kendler, K. S. A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am. J. Psychiatry 158, 1568-1578 (2001).
6. Maron, E., Hettema, J. M. & Shlik, J. Advances in molecular genetics of panic disorder. Mol. Psychiatry 15, 681-701 (2010).
7. Stein, M. B., Chartier, M. & Walker, J. R. Sleep in nondepressed patients with panic disorder, I. Systematic assessment of subjective sleep quality and sleep disturbance. Sleep 16, 724-726 (1993).
8. Overbeek, T., van Diest, R., Schruers, K., Kruizinga, F. & Griez, E. Sleep complaints in panic disorder patients. J. Nerv. Ment. Dis. 193, 488-493 (2005).
9. Hirota, T. & Fukada, Y. Resetting mechanism of central and peripheral circadian clocks in mammals. Zoolog. Sci. 21, 359-368 (2004).
10. Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptacek, L. J. & Fu, Y. H. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291, 1040-1043 (2001).
11. Carpen, J. D., Archer, S. N., Skene, D. J., Smits, M. & von Schantz, M. A singlenucleotide polymorphism in the 5'-untranslated region of the hPER2 gene is associated with diurnal preference. J. Sleep Res. 14, 293-297 (2005).
12. Lee, H. J., Kim, L., Kang, S. G., Yoon, H. K., Choi, J. E., Park, Y. M. et al. PER2 variation is associated with diurnal preference in a Korean young population. Behav. Genet. 41, 273-277 (2011).
13. Nievergelt, C. M., Kripke, D. F., Barrett, T. B., Burg, E., Remick, R. A., Sadovnick, A. D. et al. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141 B, 234-241 (2006).
14. Johansson, C., Willeit, M., Smedh, C., Ekholm, J., Paunio, T., Kieseppa, T. et al. Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference. Neuropsychopharmacology 28, 734-739 (2003).
15. Sipilä, T., Kananen, L., Greco, D., Donner, J., Silander, K., Terwilliger, J. D. et al. An association analysis of circadian genes in anxiety disorders. Biol. Psychiatry 67, 1163-1170 (2010).
16. Sheehan, D. V., Lecrubier, Y., Sheehan, K. H., Amorim, P., Janavs, J., Weiller, E. et al. The Mini-International Neuropsychiatric Interview (M. I. N. I.), the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59(Suppl 20), 22-33 (1998).
17. Barrett, J. C., Fry, B., Maller, J. & Daly, M. J. Haploview, analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005).
18. Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B. et al. The structure of haplotype blocks in the human genome. Science 296, 2225-2229 (2002).
19. Purcell, S., Cherny, S. S. & Sham, P. C. Genetic power calculator, design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19, 149-150 (2003).
20. Otowa, T., Yoshida, E., Sugaya, N., Yasuda, S., Nishimura, Y., Inoue, K. et al. Genomewide association study of panic disorder in the Japanese population. J. Hum. Genet. 54, 122-126 (2009).