Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia

Genes, Brain and Behavior

Volumn 5, Issue 2, 2006, Pages 150-157

  Mansour, H A ^a   Wood, J ^a   Logue, T ^a   Chowdari, K V ^a   Dayal, M ^a   Kupfer, D J ^a   Monk, T H ^a   Devlin, B ^a   Nimgaonkar, V L ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b WPIC   (United States)

Author keywords

ARNTL; Association; Bipolar I disorder; Circadian; Genetic; Linkage; PER3; Schizoaffective disorder; Schizophrenia; TIMELESS

Indexed keywords

ARTICLE; BIPOLAR I DISORDER; BLOOD SAMPLING; CIRCADIAN RHYTHM; COMMUNITY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; GENE LOCUS; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; UMBILICAL CORD BLOOD;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL CLOCKS; BIPOLAR DISORDER; BRAIN CHEMISTRY; CASE-CONTROL STUDIES; CELL CYCLE PROTEINS; CHRONOBIOLOGY DISORDERS; CIRCADIAN RHYTHM; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOME, HUMAN; HUMANS; INFANT, NEWBORN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; TRANSCRIPTION FACTORS;

EID: 33644790985     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2005.00147.x     Document Type: Article

References (50)

1. Abe M. Herzog E.D. Block G.D. 2000 Lithium lengthens the circadian period of individual suprachiasmatic nucleus neurons Neuroreport 11 3261 3264
2. Archer S.N. Robilliard D.L. Skene D.J. Smits M. Williams A. Arendt J. Von Schantz M. 2003 A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference Sleep 26 413 415
3. Bacanu S.A. Devlin B. Roeder K. 2000 The power of genomic control Am J Hum Genet 66 1933 1944
4. Baehr E.K. Revelle W. Eastman C.I. 2000 Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness-eveningness J Sleep Res 9 117 127
5. Basturk M. Karaaslan F. Esel E. Sofuoglu S. Tutus A. Yabanoglu I. 2001 Effects of short and long-term lithium treatment on serum prolactin levels in patients with bipolar affective disorder Prog Neuropsychopharmacol Biol Psychiatry 25 315 322
6. Benedetti F. Serretti A. Colombo C. Barbini B. Lorenzi C. Campori E. Smeraldi E. 2003 Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression Am J Med Genet 123B 23 26
7. Berrettini W.H. 2000 Are schizophrenic and bipolar disorders related? A review of family and molecular studies Biol Psychiatry 48 531 538
8. Campbell S.S. Gillin J.C. Kripke D.F. Janowsky D.S. Risch S.C. 1989 Lithium delays circadian phase of temperature and REM sleep in a bipolar depressive: a case report Psychiatry Res 27 23 29
9. Cermakian N. Boivin D.B. 2003 A molecular perspective of human circadian rhythm disorders Brain Res Brain Res Rev 42 204 220
10. Chowdari K.V. Mirnics K. Semwal P. Wood J. Lawrence E. Bhatia T. Deshpande S.N. B K.T. Ferrell R.E. Middleton F.A. Devlin B. Levitt P. Lewis D.A. Nimgaonkar V.L. 2002 Association and linkage analyses of RGS4 polymorphisms in schizophrenia Hum Mol Genet 11 1373 1380
11. Clayton D. 1999 A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission Am J Hum Genet 65 1170 1177
12. Desan P.H. Oren D.A. Malison R. Price L.H. Rosenbaum J. Smoller J. Charney D.S. Gelernter J. 2000 Genetic polymorphism at the CLOCK gene locus and major depression Am J Med Genet 96 418 421
13. Devlin B. Roeder K. Wasserman L. 2001 Genomic control, a new approach to genetic-based association studies Theor Popul Biol 60 155 166
14. Ebisawa T. Uchiyama M. Kajimura N. et al. 2001 Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome EMBO Rep 2 342 346
15. Ewens W.J. Spielman R.S. 1995 The transmission/disequilibrium test: history, subdivision, and admixture American Journal of Human Genetics 57 455 64
16. Fallin D. Cohen A. Essioux L. Chumakov I. Blumenfeld M. Cohen D. Schork N.J. 2001 Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease Genome Res 11 143 151
17. Healy D. 1987 Rhythm and blues. Neurochemical, neuropharmacological and neuropsychological implications of a hypothesis of circadian rhythm dysfunction in the affective disorders Psychopharmacology (Berl) 93 271 285
18. Holzberg D. Albrecht U. 2003 The circadian clock: a manager of biochemical processes within the organism J Neuroendocrinol 15 339 343
19. Horne J.A. Ostberg O. 1976 A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms Int J Chronobiol 4 97 110
20. Johansson C. Willeit M. Smedh C. Ekholm J. Paunio T. Kieseppa T. Lichtermann D. Praschak-Rieder N. Neumeister A. Nilsson L.G. Kasper S. Peltonen L. Adolfsson R. Schalling M. Partonen T. 2003 Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference Neuropsychopharmacology 28 734 739
21. Katz G. Durst R. Zislin Y. Barel Y. Knobler H.Y. 2001 Psychiatric aspects of jet lag: review and hypothesis Med Hypotheses 56 20 23
22. Katzenberg D. Young T. Finn L. Lin L. King D.P. Takahashi J.S. Mignot E. 1998 A CLOCK polymorphism associated with human diurnal preference Sleep 21 569 576
23. Kennedy S.H. Kutcher S.P. Ralevski E. Brown G.M. 1996 Nocturnal melatonin and 24-hour 6-sulphatoxymelatonin levels in various phases of bipolar affective disorder Psychiatry Res 63 219 222
24. Kessler R.C. McGonagle K.A. Zhao S. Nelson C.B. Hughes M. Eshleman S. Wittchen H.U. Kendler K.S. 1994 Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey Arch Gen Psychiatry 51 8 19
25. Kripke D.F. Mullaney D.J. Atkinson M. Wolf S. 1978 Circadian rhythm disorders in manic-depressives Biol Psychiatry 13 335 351
26. Kruglyak L. 1999 Prospects for whole-genome linkage disequilibrium mapping of common disease genes Nat Genet 22 139 144
27. Lange C. Demeo D. Silverman E.K. Weiss S.T. Laird N.M. 2004 PBAT: tools for family-based association studies Am J Hum Genet 74 367 369
28. Leibenluft E. Feldman-Naim S. Turner E.H. Schwartz P.J. Wehr T.A. 1996 Salivary and plasma measures of dim light melatonin onset (DLMO) in patients with rapid cycling bipolar disorder Biol Psychiatry 40 731 735
29. Manji H.K. Moore G.J. Chen G. 2001 Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilizers Br J Psychiatry Suppl 41 s107 s119
30. Mansour H. Wood J. Logue T. Chowdari K.V. Dayal M. Monk T. Kupfer D. Devlin B. Nimgaonkar V. 2005 Circadian phase variation in Bipolar I Disorder (BD1) Chronobiol Int, in press
31. Matsumoto M. Kamata S. Naoe H. Mutoh F. Chiba S. 1996 [Investigation of the actual conditions of hospital nurses working on three rotating shifts: questionnaire results of shift work schedules, feelings of sleep and fatigue, and depression] Seishin Shinkeigaku Zasshi 98 11 26
32. Mellerup E.T. Lauritsen B. Dam H. Rafaelson O.J. 1976 Lithium effects on diurnal rhythm of calcium, magnesium, and phosphate metabolism in manic-melancholic disorder Acta Psychiatr Scand 53 360 370
33. Mendlewicz J. 1982 Circadian variation of serum TSH in unipolar and bipolar depression Psychiatry Res 7 388 389
34. Mendlewicz J. Linkowski P. Kerkhofs M. Leproult R. Copinschi G. Van Cauter E. 1999 Genetic control of 24-hour growth hormone secretion in man: a twin study J Clin Endocrinol Metab 84 856 862
35. Mitterauer B. 2000 Clock genes, feedback loops and their possible role in the etiology of bipolar disorders: an integrative model Med Hypotheses 55 155 159
36. Monk T.H. Reynolds C.F.R. Buysse D.J. Hoch C.C. Jarrett D.B. Jennings J.R. Kupfer D.J. 1991 Circadian characteristics of healthy 80-year-olds and their relationship to objectively recorded sleep J Gerontol 46 M171 M175
37. Nair R.P. Stuart P. Henseler T. Jenish S. Chia N.V. Westphal E. Schork N.J. E. 2000 Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C Am J Hum Genet 66 1833 1844
38. Nebel L.E. Howell R.H. Krantz D.S. Falconer J.J. Gottdiener J.S. Gabbay F.H. 1996 The circadian variation of cardiovascular stress levels and reactivity: relationship to individual differences in morningness/eveningness Psychophysiology 33 273 281
39. Nurnberger J.I.J.R. Berrettini W. Simmons-Alling S. Lawrence D. Brittain H. 1990 Blunted ACTH and cortisol response to afternoon tryptophan infusion in euthymic bipolar patients Psychiatry Res 31 57 67
40. Nurnberger J.I.J.R. Blehar M.C. Kaufmann C.A. York-Cooler C. Simpson S.G. Harkavy-Friedman J. Severe J.B. Malaspina D. Reich T. 1994 Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative Arch Gen Psychiatry 51 849 859 ; discussion 863-864.
41. O'Connell J.R. Weeks D.E. 1998 PedCheck: a program for identification of genotype incompatibilties in linkage analysis Am J Hum Genet 63 259 266
42. Ranade S.S. Mansour H. Wood J. Chowdari K.V. Brar L.K. Kupfer D.J. Nimgaonkar V.L. 2003 Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder Am J Med Genet 121B 28 34
43. Robilliard D.L. Archer S.N. Arendt J. Lockley S.W. Hack L.M. English J. Leger D. Smits M.G. Williams A. Skene D.J. Von Schantz M. 2002 The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects J Sleep Res 11 305 312
44. Sarai K. Kayano M. 1968 The level and diurnal rhythm of serum serotonin in manic-depressive patients Folia Psychiatr Neurol Jpn 22 271 281
45. Schreiner R. Mirisch S. Vesely Z. Wiegand M.H. 2001 Sleep and sleep-wake cycle in an 81-year-old patient with de novo ultra-rapid cycling bipolar disorder Eur Arch Psychiatry Clin Neurosci 251 29 31
46. Serretti A. Benedetti F. Mandelli L. Lorenzi C. Pirovano A. Colombo C. Smeraldi E. 2003 Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism Am J Med Genet 121B 35 38
47. Smith C.S. Reilly C. Midkiff K. 1989 Evaluation of three circadian rhythm questionnaires with suggestions for an improved measure of morningness J Appl Psychol 74 728 738
48. Spielman R.S. McGinnis R.E. Ewens W.J. 1993 Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM) American Journal of Human Genetics 52 506 16
49. Toh K.L. Jones C.R. He Y. Eide E.J. Hinz W.A. Virshup D.M. Ptacek L.J. Fu Y.H. 2001 An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome Science 291 1040 1043
50. Vink J.M. Groot A.S. Kerkhof G.A. Boomsma D.I. 2001 Genetic analysis of morningness and eveningness Chronobiol Int 18 809 822