Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart

American Journal of Obstetrics and Gynecology

Volumn 212, Issue 5, 2015, Pages 650.e1-650.e11

  Wang, Fang ^a   Reece, E Albert ^a   Yang, Peixin ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

1 transgenic; beta signaling; Embryonic heart; growth factor; mice transforming; oxidative stress; superoxide dismutase

Indexed keywords

4 HYDROXYNONENAL; COPPER ZINC SUPEROXIDE DISMUTASE; MALONALDEHYDE; PHOSPHOPROTEIN; RECOMBINANT PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TEMPOL; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; 4-HYDROXY-2-NONENAL; ALDEHYDE; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE; TGFB1 PROTEIN, MOUSE; TGFB2 PROTEIN, MOUSE; TGFB3 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYOPATHY; EX VIVO STUDY; EXPLANT; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; HEART; HEART DEVELOPMENT; HYPERGLYCEMIA; MATERNAL DIABETES MELLITUS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE CULTURE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; EMBRYOLOGY; GENETICS; HEART MUSCLE; METABOLISM; PHOSPHORYLATION; PREGNANCY; PREGNANCY DIABETES MELLITUS;

ALDEHYDES; ANIMALS; FEMALE; HEART; HYPERGLYCEMIA; MALONDIALDEHYDE; MICE; MICE, TRANSGENIC; MYOCARDIUM; OXIDATIVE STRESS; PHOSPHORYLATION; PREGNANCY; PREGNANCY IN DIABETICS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 84928825031     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2015.01.014     Document Type: Article

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