메뉴 건너뛰기




Volumn 9, Issue 3, 2015, Pages

Recombinant NAD-dependent SIR-2 Protein of Leishmania donovani: Immunobiochemical Characterization as a Potential Vaccine against Visceral Leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLUTARALDEHYDE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; NITRIC OXIDE; RECOMBINANT NAD DEPENDENT SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; LEISHMANIA VACCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTOZOAL PROTEIN; RECOMBINANT VACCINE; SIRTUIN 2;

EID: 84928817150     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003557     Document Type: Article
Times cited : (22)

References (70)
  • 1
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • Herwaldt BL, (1999) Leishmaniasis. Lancet 354: 1191–1199. 10513726
    • (1999) Lancet , vol.354 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 2
    • 0036319712 scopus 로고    scopus 로고
    • Visceral Leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda
    • Guerin PJ, Olliaro P, Sundar S, Boelaert M, Croft SL, et al. (2002) Visceral Leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. Lancet Infect Dis 2: 494–501. 12150849
    • (2002) Lancet Infect Dis , vol.2 , pp. 494-501
    • Guerin, P.J.1    Olliaro, P.2    Sundar, S.3    Boelaert, M.4    Croft, S.L.5
  • 3
    • 33744898842 scopus 로고    scopus 로고
    • Serious underreporting of visceral Leishmaniasis through passive case reporting in Bihar
    • Singh SP, Reddy DC, Rai M, Sundar S, (2006) Serious underreporting of visceral Leishmaniasis through passive case reporting in Bihar, India. Trop Med Int Health 11: 899–905. 16772012
    • (2006) India. Trop Med Int Health , vol.11 , pp. 899-905
    • Singh, S.P.1    Reddy, D.C.2    Rai, M.3    Sundar, S.4
  • 4
    • 74049110828 scopus 로고    scopus 로고
    • Estimation of under-reporting of visceral Leishmaniasis cases in Bihar, India
    • Singh VP, Ranjan A, Topno RK, Verma RB, Siddique NA, et al.(2010) Estimation of under-reporting of visceral Leishmaniasis cases in Bihar, India. Am J Trop Med Hyg 82: 9–11. doi: 10.4269/ajtmh.2010.09-0235 20064987
    • (2010) Am J Trop Med Hyg , vol.82 , pp. 9-11
    • Singh, V.P.1    Ranjan, A.2    Topno, R.K.3    Verma, R.B.4    Siddique, N.A.5
  • 5
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: current situation and new perspectives
    • Desjeux P, (2004) Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 27: 305–318. 15225981
    • (2004) Comp Immunol Microbiol Infect Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 6
    • 0035067363 scopus 로고    scopus 로고
    • Leishmaniasis: current status of vaccine development
    • Handman E, (2001) Leishmaniasis: current status of vaccine development. Clin Microbiol Rev 14: 229–243 11292637
    • (2001) Clin Microbiol Rev , vol.14 , pp. 229-243
    • Handman, E.1
  • 7
    • 0021075679 scopus 로고
    • Cell-mediated immune response in Indian kala-azar and post-kala-azar dermal Leishmaniasis
    • Haldar JP, Ghose S, Saha KC, Ghose AC, (1983) Cell-mediated immune response in Indian kala-azar and post-kala-azar dermal Leishmaniasis. Infect Immun 42: 702–707. 6642649
    • (1983) Infect Immun , vol.42 , pp. 702-707
    • Haldar, J.P.1    Ghose, S.2    Saha, K.C.3    Ghose, A.C.4
  • 8
    • 0027159096 scopus 로고
    • In vivo cytokine profiles in patients with kala-azar marked elevation of both interleukin-10 and interferon-gamma
    • Karp CL, el-Safi SH, Wynn TA, Satti MM, Kordofani AM, et al. (1993) In vivo cytokine profiles in patients with kala-azar marked elevation of both interleukin-10 and interferon-gamma. J Clin Invest 91: 1644–1648. 8097208
    • (1993) J Clin Invest , vol.91 , pp. 1644-1648
    • Karp, C.L.1    el-Safi, S.H.2    Wynn, T.A.3    Satti, M.M.4    Kordofani, A.M.5
  • 9
    • 28344439312 scopus 로고    scopus 로고
    • Immune response in human visceral leishmaniasis: analysis of the correlation between innate immunity cytokine profile and disease outcome
    • Peruhype-Magalhaes V, Martins-Filho OA, Prata A, Silva Lde A, Rabello A, et al. (2005) Immune response in human visceral leishmaniasis: analysis of the correlation between innate immunity cytokine profile and disease outcome. Scand J Immunol 62: 487–495 16305646
    • (2005) Scand J Immunol , vol.62 , pp. 487-495
    • Peruhype-Magalhaes, V.1    Martins-Filho, O.A.2    Prata, A.3    Silva Lde, A.4    Rabello, A.5
  • 10
    • 0027522629 scopus 로고
    • Leishmania donovani reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis
    • Kemp M, Kurtzhals JA, Bendtzen K, Poulsen LK, Hansen MB, et al. (1993) Leishmania donovani reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis. Infect Immun 61: 1069–1073. 8432588
    • (1993) Infect Immun , vol.61 , pp. 1069-1073
    • Kemp, M.1    Kurtzhals, J.A.2    Bendtzen, K.3    Poulsen, L.K.4    Hansen, M.B.5
  • 11
    • 33947368687 scopus 로고    scopus 로고
    • Proteomic approach for identification and characterization of novel immunostimulatory proteins from soluble antigens of Leishmania donovani promastigotes
    • Gupta SK, Sisodia BS, Sinha S, Hajela K, Naik S, et al. (2007) Proteomic approach for identification and characterization of novel immunostimulatory proteins from soluble antigens of Leishmania donovani promastigotes. Proteomics 7: 816–823. 17295358
    • (2007) Proteomics , vol.7 , pp. 816-823
    • Gupta, S.K.1    Sisodia, B.S.2    Sinha, S.3    Hajela, K.4    Naik, S.5
  • 12
    • 0029928666 scopus 로고    scopus 로고
    • A Leishmania major protein with extensive homology to silent information regulator 2 of Saccharomyces cerevisiae
    • Yahiaoui B, Taibi A, Ouaissi A, (1996) A Leishmania major protein with extensive homology to silent information regulator 2 of Saccharomyces cerevisiae. Gene 169: 115–118. 8635734
    • (1996) Gene , vol.169 , pp. 115-118
    • Yahiaoui, B.1    Taibi, A.2    Ouaissi, A.3
  • 13
    • 0037151779 scopus 로고    scopus 로고
    • Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death
    • Vergnes B, Sereno D, Madjidian-Sereno N, Lemesre JL, Ouaissi A, (2002) Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death. Gene 296: 139–150. 12383511
    • (2002) Gene , vol.296 , pp. 139-150
    • Vergnes, B.1    Sereno, D.2    Madjidian-Sereno, N.3    Lemesre, J.L.4    Ouaissi, A.5
  • 14
    • 28044445460 scopus 로고    scopus 로고
    • Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation
    • Vergnes B, Sereno D, Tavares J, Cordeiro-da-Silva A, Vanhille L, et al. (2005) Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation. Gene 363: 85–96. 16236469
    • (2005) Gene , vol.363 , pp. 85-96
    • Vergnes, B.1    Sereno, D.2    Tavares, J.3    Cordeiro-da-Silva, A.4    Vanhille, L.5
  • 15
    • 16244405883 scopus 로고    scopus 로고
    • Immunostimulatory cellular responses of cured Leishmania-infected patients and hamsters against the integral membrane proteins and non-membranous soluble proteins of a recent clinical isolate of Leishmania donovani
    • Garg R, Gupta SK, Tripathi P, Naik S, Sundar S, et al. (2005) Immunostimulatory cellular responses of cured Leishmania-infected patients and hamsters against the integral membrane proteins and non-membranous soluble proteins of a recent clinical isolate of Leishmania donovani. Clin Exp Immunol 140: 149–156. 15762886
    • (2005) Clin Exp Immunol , vol.140 , pp. 149-156
    • Garg, R.1    Gupta, S.K.2    Tripathi, P.3    Naik, S.4    Sundar, S.5
  • 16
    • 21644432930 scopus 로고    scopus 로고
    • Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persist in in vitro and in vivo experimental models
    • Dube A, Singh N, Sundar S, (2005) Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persist in in vitro and in vivo experimental models. Parasitol Res 96: 216–223. 15868188
    • (2005) Parasitol Res , vol.96 , pp. 216-223
    • Dube, A.1    Singh, N.2    Sundar, S.3
  • 18
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin H, Staehelin T, Gordon J, (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 76: 4350–4354. 388439
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 20
    • 77954296666 scopus 로고    scopus 로고
    • A new bioinformatics analysis tools framework at EMBL-EBI
    • Goujon M, McWilliam H, Li W, Valentin F, Squizzato S, et al.(2010) A new bioinformatics analysis tools framework at EMBL-EBI. Nucleic Acids Res 38: W695–699. doi: 10.1093/nar/gkq313 20439314
    • (2010) Nucleic Acids Res , vol.38 , pp. W695-699
    • Goujon, M.1    McWilliam, H.2    Li, W.3    Valentin, F.4    Squizzato, S.5
  • 21
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura K, Peterson D, Peterson N, Stecher G, Nei M, et al.(2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28: 2731–2739. doi: 10.1093/molbev/msr121 21546353
    • (2011) Mol Biol Evol , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5
  • 22
    • 84870450672 scopus 로고    scopus 로고
    • MEGA-CC: computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis
    • Kumar S, Stecher G, Peterson D, Tamura K, (2012) MEGA-CC: computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis. Bioinformatics 28: 2685–2686. doi: 10.1093/bioinformatics/bts507 22923298
    • (2012) Bioinformatics , vol.28 , pp. 2685-2686
    • Kumar, S.1    Stecher, G.2    Peterson, D.3    Tamura, K.4
  • 23
    • 0020965531 scopus 로고
    • Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data
    • Nei M, Tajima F, Tateno Y, (1983) Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data. J Mol Evol 19: 153–170. 6571220
    • (1983) J Mol Evol , vol.19 , pp. 153-170
    • Nei, M.1    Tajima, F.2    Tateno, Y.3
  • 24
    • 84880772571 scopus 로고    scopus 로고
    • Evolution of primary HIV drug resistance in a subtype C dominated epidemic in Mozambique
    • Bila DC, Young P, Merks H, Vubil AS, Mahomed M, et al.(2013) Evolution of primary HIV drug resistance in a subtype C dominated epidemic in Mozambique. PLoS One 8: e68213. doi: 10.1371/journal.pone.0068213 23935858
    • (2013) PLoS One , vol.8 , pp. e68213
    • Bila, D.C.1    Young, P.2    Merks, H.3    Vubil, A.S.4    Mahomed, M.5
  • 25
    • 84877154486 scopus 로고    scopus 로고
    • Molecular mapping and breeding with microsatellite markers
    • Lightfoot DA, Iqbal MJ, (2013) Molecular mapping and breeding with microsatellite markers. Methods Mol Biol 1006: 297–317. doi: 10.1007/978-1-62703-389-3_20 23546799
    • (2013) Methods Mol Biol , vol.1006 , pp. 297-317
    • Lightfoot, D.A.1    Iqbal, M.J.2
  • 26
    • 84866995283 scopus 로고    scopus 로고
    • A comparative-based phylogenetic study in the evolution of 16S rRNA and rad a genes in Archaea
    • Sambasiva Rao KR, Srinivasa Rao D, (2012) A comparative-based phylogenetic study in the evolution of 16S rRNA and rad a genes in Archaea. Int J Data Min Bioinform 6: 396–405. 23155770
    • (2012) Int J Data Min Bioinform , vol.6 , pp. 396-405
    • Sambasiva Rao, K.R.1    Srinivasa Rao, D.2
  • 27
    • 44949239504 scopus 로고    scopus 로고
    • Discovering sequence motifs with arbitrary insertions and deletions
    • Frith MC, Saunders NF, Kobe B, Bailey TL, (2008) Discovering sequence motifs with arbitrary insertions and deletions. PLoS Comput Biol 4: e1000071. doi: 10.1371/journal.pcbi.1000071 18437229
    • (2008) PLoS Comput Biol , vol.4 , pp. e1000071
    • Frith, M.C.1    Saunders, N.F.2    Kobe, B.3    Bailey, T.L.4
  • 28
    • 67849122320 scopus 로고    scopus 로고
    • MEME SUITE: tools for motif discovery and searching
    • Bailey TL, Boden M, Buske FA, Frith M, Grant CE, et al. (2009) MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res 37: W202–208. doi: 10.1093/nar/gkp335 19458158
    • (2009) Nucleic Acids Res , vol.37 , pp. W202-208
    • Bailey, T.L.1    Boden, M.2    Buske, F.A.3    Frith, M.4    Grant, C.E.5
  • 29
  • 30
    • 78651285748 scopus 로고    scopus 로고
    • CDD: a Conserved Domain Database for the functional annotation of proteins
    • Marchler-Bauer A, Lu S, Anderson JB, Chitsaz F, Derbyshire MK, et al.(2011) CDD: a Conserved Domain Database for the functional annotation of proteins. Nucleic Acids Res 39: D225–229. doi: 10.1093/nar/gkq1189 21109532
    • (2011) Nucleic Acids Res , vol.39 , pp. D225-229
    • Marchler-Bauer, A.1    Lu, S.2    Anderson, J.B.3    Chitsaz, F.4    Derbyshire, M.K.5
  • 31
  • 33
    • 25444476693 scopus 로고    scopus 로고
    • Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method
    • Peters B, Sette A, (2005) Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method. BMC Bioinformatics 6: 132. 15927070
    • (2005) BMC Bioinformatics , vol.6 , pp. 132
    • Peters, B.1    Sette, A.2
  • 34
    • 71949096416 scopus 로고    scopus 로고
    • Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior
    • Kim Y, Sidney J, Pinilla C, Sette A, Peters B, (2009) Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior. BMC Bioinformatics 10: 394. doi: 10.1186/1471-2105-10-394 19948066
    • (2009) BMC Bioinformatics , vol.10 , pp. 394
    • Kim, Y.1    Sidney, J.2    Pinilla, C.3    Sette, A.4    Peters, B.5
  • 35
    • 39549085122 scopus 로고    scopus 로고
    • Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries
    • Sidney J, Assarsson E, Moore C, Ngo S, Pinilla C, et al. (2008) Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries. Immunome Res 4: 2. doi: 10.1186/1745-7580-4-2 18221540
    • (2008) Immunome Res , vol.4 , pp. 2
    • Sidney, J.1    Assarsson, E.2    Moore, C.3    Ngo, S.4    Pinilla, C.5
  • 36
    • 33746132748 scopus 로고    scopus 로고
    • A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus
    • Moutaftsi M, Peters B, Pasquetto V, Tscharke DC, Sidney J, et al. (2006) A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus. Nat Biotechnol 24: 817–819. 16767078
    • (2006) Nat Biotechnol , vol.24 , pp. 817-819
    • Moutaftsi, M.1    Peters, B.2    Pasquetto, V.3    Tscharke, D.C.4    Sidney, J.5
  • 37
    • 59449094834 scopus 로고    scopus 로고
    • NetMHCpan, a method for MHC class I binding prediction beyond humans
    • Hoof I, Peters B, Sidney J, Pedersen LE, Sette A, et al. (2009) NetMHCpan, a method for MHC class I binding prediction beyond humans. Immunogenetics 61: 1–13. doi: 10.1007/s00251-008-0341-z 19002680
    • (2009) Immunogenetics , vol.61 , pp. 1-13
    • Hoof, I.1    Peters, B.2    Sidney, J.3    Pedersen, L.E.4    Sette, A.5
  • 38
    • 84879524693 scopus 로고    scopus 로고
    • Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology
    • Xiang Z, He Y, (2013) Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology. BMC Bioinformatics 14 Suppl 4: S2. doi: 10.1186/1471-2105-14-S4-S2 23514126
    • (2013) BMC Bioinformatics , vol.14 , pp. S2
    • Xiang, Z.1    He, Y.2
  • 39
  • 40
    • 84883262273 scopus 로고    scopus 로고
    • Computational approaches to identify common subunit vaccine candidates against bacterial meningitis
    • Munikumar M, Priyadarshini IV, Pradhan D, Umamaheswari A, Vengamma B, (2013) Computational approaches to identify common subunit vaccine candidates against bacterial meningitis. Interdiscip Sci 5: 155–164. doi: 10.1007/s12539-013-0161-1 23740398
    • (2013) Interdiscip Sci , vol.5 , pp. 155-164
    • Munikumar, M.1    Priyadarshini, I.V.2    Pradhan, D.3    Umamaheswari, A.4    Vengamma, B.5
  • 41
    • 34248573507 scopus 로고    scopus 로고
    • Molecular diversity of HLA-A,-B and -C alleles in a North Indian population as determined by PCR-SSOP
    • Rani R, Marcos C, Lazaro AM, Zhang Y, Stastny P, (2007) Molecular diversity of HLA-A,-B and -C alleles in a North Indian population as determined by PCR-SSOP. Int J Immunogenet 34: 201–208 17504510
    • (2007) Int J Immunogenet , vol.34 , pp. 201-208
    • Rani, R.1    Marcos, C.2    Lazaro, A.M.3    Zhang, Y.4    Stastny, P.5
  • 42
    • 37649022489 scopus 로고    scopus 로고
    • Determination of protein oligomerization state: two approaches based on glutaraldehyde crosslinking
    • Fadouloglou VE, Kokkinidis M, Glykos NM, (2008) Determination of protein oligomerization state: two approaches based on glutaraldehyde crosslinking. Anal Biochem 373: 404–406. 18023408
    • (2008) Anal Biochem , vol.373 , pp. 404-406
    • Fadouloglou, V.E.1    Kokkinidis, M.2    Glykos, N.M.3
  • 43
    • 2942564591 scopus 로고    scopus 로고
    • Sirtuins: Sir2-related NAD-dependent protein deacetylases
    • North BJ, Verdin E, (2004) Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol 5: 224. 15128440
    • (2004) Genome Biol , vol.5 , pp. 224
    • North, B.J.1    Verdin, E.2
  • 44
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • Ding AH, Nathan CF, Stuehr DJ, (1988) Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol 141: 2407–2412. 3139757
    • (1988) J Immunol , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 45
    • 68949108180 scopus 로고    scopus 로고
    • Immunization with the DNA-encoding N-terminal domain of proteophosphoglycan of Leishmania donovani generates Th1-type immunoprotective response against experimental visceral leishmaniasis
    • Samant M, Gupta R, Kumari S, Misra P, Khare P, et al. (2009) Immunization with the DNA-encoding N-terminal domain of proteophosphoglycan of Leishmania donovani generates Th1-type immunoprotective response against experimental visceral leishmaniasis. J Immunol 183: 470–479. doi: 10.4049/jimmunol.0900265 19542458
    • (2009) J Immunol , vol.183 , pp. 470-479
    • Samant, M.1    Gupta, R.2    Kumari, S.3    Misra, P.4    Khare, P.5
  • 46
    • 0031948654 scopus 로고    scopus 로고
    • Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis
    • Melby PC, Tryon VV, Chandrasekar B, Freeman GL, (1998) Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis. Infect Immun 66: 2135–2142. 9573100
    • (1998) Infect Immun , vol.66 , pp. 2135-2142
    • Melby, P.C.1    Tryon, V.V.2    Chandrasekar, B.3    Freeman, G.L.4
  • 48
    • 33751020273 scopus 로고    scopus 로고
    • Peptide length-based prediction of peptide-MHC class II binding
    • Chang ST, Ghosh D, Kirschner DE, Linderman JJ, (2006) Peptide length-based prediction of peptide-MHC class II binding. Bioinformatics 22: 2761–2767. 17000752
    • (2006) Bioinformatics , vol.22 , pp. 2761-2767
    • Chang, S.T.1    Ghosh, D.2    Kirschner, D.E.3    Linderman, J.J.4
  • 49
    • 49549114854 scopus 로고    scopus 로고
    • Induction of Th1-type cellular responses in cured/exposed Leishmania-infected patients and hamsters against polyproteins of soluble Leishmania donovani promastigotes ranging from 89.9 to 97.1 kDa
    • Kumari S, Samant M, Khare P, Sundar S, Sinha S, et al. (2008) Induction of Th1-type cellular responses in cured/exposed Leishmania-infected patients and hamsters against polyproteins of soluble Leishmania donovani promastigotes ranging from 89.9 to 97.1 kDa. Vaccine 26: 4813–4818. doi: 10.1016/j.vaccine.2008.06.102 18656517
    • (2008) Vaccine , vol.26 , pp. 4813-4818
    • Kumari, S.1    Samant, M.2    Khare, P.3    Sundar, S.4    Sinha, S.5
  • 50
    • 0018644035 scopus 로고
    • MAR1-a Regulator of the HMa and HMalpha Loci in saccharomyces cerevisiae
    • Klar AJ, Fogel S, Macleod K, (1979) MAR1-a Regulator of the HMa and HMalpha Loci in saccharomyces cerevisiae. Genetics 93: 37–50. 17248968
    • (1979) Genetics , vol.93 , pp. 37-50
    • Klar, A.J.1    Fogel, S.2    Macleod, K.3
  • 51
    • 0037023326 scopus 로고    scopus 로고
    • The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation
    • Bell SD, Botting CH, Wardleworth BN, Jackson SP, White MF, (2002) The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation. Science 296: 148–151. 11935028
    • (2002) Science , vol.296 , pp. 148-151
    • Bell, S.D.1    Botting, C.H.2    Wardleworth, B.N.3    Jackson, S.P.4    White, M.F.5
  • 52
    • 0347457075 scopus 로고    scopus 로고
    • Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
    • Starai VJ, Celic I, Cole RN, Boeke JD, Escalante-Semerena JC, (2002) Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science 298: 2390–2392. 12493915
    • (2002) Science , vol.298 , pp. 2390-2392
    • Starai, V.J.1    Celic, I.2    Cole, R.N.3    Boeke, J.D.4    Escalante-Semerena, J.C.5
  • 53
    • 0037355004 scopus 로고    scopus 로고
    • The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation
    • Astrom SU, Cline TW, Rine J, (2003) The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation. Genetics 163: 931–937. 12663533
    • (2003) Genetics , vol.163 , pp. 931-937
    • Astrom, S.U.1    Cline, T.W.2    Rine, J.3
  • 54
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, et al. (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191–196. 12939617
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4    Lavu, S.5
  • 55
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M, McVey M, Guarente L, (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13: 2570–2580. 10521401
    • (1999) Genes Dev , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 56
    • 8644224064 scopus 로고    scopus 로고
    • Sir2 mediates longevity in the fly through a pathway related to calorie restriction
    • Rogina B, Helfand SL, (2004) Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci U S A 101: 15998–16003. 15520384
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15998-16003
    • Rogina, B.1    Helfand, S.L.2
  • 57
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum HA, Guarente L, (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227–230. 11242085
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 58
    • 77952413052 scopus 로고    scopus 로고
    • SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
    • Luthi-Carter R, Taylor DM, Pallos J, Lambert E, Amore A, et al.(2010) SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Proc Natl Acad Sci U S A 107: 7927–7932. doi: 10.1073/pnas.1002924107 20378838
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7927-7932
    • Luthi-Carter, R.1    Taylor, D.M.2    Pallos, J.3    Lambert, E.4    Amore, A.5
  • 59
    • 33746812188 scopus 로고    scopus 로고
    • Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases
    • Ouaissi M, Ouaissi A, (2006) Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases. J Biomed Biotechnol 2006: 13474. 16883049
    • (2006) J Biomed Biotechnol , vol.2006 , pp. 13474
    • Ouaissi, M.1    Ouaissi, A.2
  • 60
    • 33750853289 scopus 로고    scopus 로고
    • Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies
    • Silvestre R, Cordeiro-da-Silva A, Tavares J, Sereno D, Ouaissi A, (2006) Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies. Immunology 119: 529–540. 17026719
    • (2006) Immunology , vol.119 , pp. 529-540
    • Silvestre, R.1    Cordeiro-da-Silva, A.2    Tavares, J.3    Sereno, D.4    Ouaissi, A.5
  • 62
    • 0026062981 scopus 로고
    • Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages
    • Liew FY, Li Y, Moss D, Parkinson C, Rogers MV, et al. (1991) Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages. Eur J Immunol 21: 3009–3014. 1721024
    • (1991) Eur J Immunol , vol.21 , pp. 3009-3014
    • Liew, F.Y.1    Li, Y.2    Moss, D.3    Parkinson, C.4    Rogers, M.V.5
  • 63
    • 0025820205 scopus 로고
    • Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like cell lines
    • Holaday BJ, Sadick MD, Wang ZE, Reiner SL, Heinzel FP, et al. (1991) Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like cell lines. J Immunol 147: 1653–1658. 1831830
    • (1991) J Immunol , vol.147 , pp. 1653-1658
    • Holaday, B.J.1    Sadick, M.D.2    Wang, Z.E.3    Reiner, S.L.4    Heinzel, F.P.5
  • 64
  • 65
    • 0025972756 scopus 로고
    • Characterization of a membrane antigen of Leishmania amazonensis that stimulates human immune responses
    • Burns JM, Jr.Scott JM, Carvalho EM, Russo DM, March CJ, et al. (1991) Characterization of a membrane antigen of Leishmania amazonensis that stimulates human immune responses. J Immunol 146: 742–748. 1824776
    • (1991) J Immunol , vol.146 , pp. 742-748
    • Burns, J.M.1    Scott, J.M.2    Carvalho, E.M.3    Russo, D.M.4    March, C.J.5
  • 67
    • 0026598337 scopus 로고
    • Leishmania chagasi antigens recognized in cured visceral leishmaniasis and asymptomatic infection
    • White AC, Jr.Castes M, Garcia L, Trujillo D, Zambrano L, (1992) Leishmania chagasi antigens recognized in cured visceral leishmaniasis and asymptomatic infection. Am J Trop Med Hyg 46: 123–131. 1539745
    • (1992) Am J Trop Med Hyg , vol.46 , pp. 123-131
    • White, A.C.1    Castes, M.2    Garcia, L.3    Trujillo, D.4    Zambrano, L.5
  • 68
    • 0034101408 scopus 로고    scopus 로고
    • Distinct innate and acquired immune responses to Leishmania in putative susceptible and resistant human populations endemically exposed to L. (Viannia) panamensis infection
    • Bosque F, Saravia NG, Valderrama L, Milon G, (2000) Distinct innate and acquired immune responses to Leishmania in putative susceptible and resistant human populations endemically exposed to L. (Viannia) panamensis infection. Scand J Immunol 51: 533–541. 10792848
    • (2000) Scand J Immunol , vol.51 , pp. 533-541
    • Bosque, F.1    Saravia, N.G.2    Valderrama, L.3    Milon, G.4
  • 69
    • 0026586443 scopus 로고
    • Selective inability of spleen antigen presenting cells from Leishmania donovani infected hamsters to mediate specific T cell proliferation to parasite antigens
    • Rodrigues Junior V, Da Silva JS, Campos-Neto A, (1992) Selective inability of spleen antigen presenting cells from Leishmania donovani infected hamsters to mediate specific T cell proliferation to parasite antigens. Parasite Immunol 14: 49–58. 1557230
    • (1992) Parasite Immunol , vol.14 , pp. 49-58
    • Rodrigues Junior, V.1    Da Silva, J.S.2    Campos-Neto, A.3
  • 70
    • 18944378937 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis
    • Basu R, Bhaumik S, Basu JM, Naskar K, De T, et al. (2005) Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis. J Immunol 174: 7160–7171. 15905560
    • (2005) J Immunol , vol.174 , pp. 7160-7171
    • Basu, R.1    Bhaumik, S.2    Basu, J.M.3    Naskar, K.4    De, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.