Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Nature

Volumn 520, Issue 7549, 2015, Pages 702-705

  Ohto, Umeharu ^a   Shibata, Takuma ^a,b   Tanji, Hiromi ^a   Ishida, Hanako ^a   Krayukhina, Elena ^c,d   Uchiyama, Susumu ^c   Miyake, Kensuke ^a   Shimizu, Toshiyuki ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d U Medico Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TOLL LIKE RECEPTOR 9; LIGAND;

BACTERIUM; DNA; FRAGMENTATION; HOST-PATHOGEN INTERACTION; IMMUNE RESPONSE; IMMUNITY; INHIBITOR; MOLECULAR ANALYSIS;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CPG ISLAND; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; DNA BINDING; DNA METHYLATION; DNA RECOGNITION; HUMAN; HUMAN CELL; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; RAT; SEDIMENTATION RATE; STOICHIOMETRY; ULTRACENTRIFUGATION; WILD TYPE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS);

ANIMALS; BASE SEQUENCE; CPG ISLANDS; CRYSTALLOGRAPHY, X-RAY; DNA; HUMANS; LIGANDS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 9;

EID: 84928791608     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14138     Document Type: Article

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