Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice

Journal of Virology

Volumn 85, Issue 21, 2011, Pages 11208-11219

  Marcelin, Glendie ^a   Aldridge, Jerry R ^a   Duan, Susu ^a   Ghoneim, Hazem E ^a   Rehg, Jerold ^a   Marjuki, Henju ^a,b   Boon, Adrianus C M ^a,c   McCullers, Jonathan A ^a   Webby, Richard J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; GAMMA INTERFERON; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; INFLUENZA VACCINE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; NITRITE; TUMOR NECROSIS FACTOR ALPHA;

2009 H1N1 INFLUENZA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MIGRATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; INNATE IMMUNITY; LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG INFILTRATE; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NOSE CAVITY; PREGNANCY; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TISSUE REGENERATION; TISSUE REPAIR; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INFLUENZA A VIRUS, H1N1 SUBTYPE; LUNG; MACROPHAGES; MICE; MICE, INBRED BALB C; NEUTROPHILS; NITRIC OXIDE; ORTHOMYXOVIRIDAE INFECTIONS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RODENT DISEASES; VIRAL LOAD;

ANIMALIA; MUS; ORTHOMYXOVIRIDAE;

EID: 80055114663     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00654-11     Document Type: Article

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