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Volumn 20, Issue 4, 2015, Pages 6925-6940

Identification of the chemical constituents in aqueous extract of Zhi-Qiao and evaluation of its antidepressant effect

Author keywords

Antidepressant; Citrus aurantium; PC12 cells; UPLC Q TOF MS

Indexed keywords

ANTIDEPRESSANT AGENT; HERBACEOUS AGENT; PLANT EXTRACT;

EID: 84928742984     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules20046925     Document Type: Article
Times cited : (46)

References (34)
  • 1
    • 4444253164 scopus 로고    scopus 로고
    • Citrus aurantium, an ingredient of dietary supplements marketed for weight loss: Current status of clinical and basic research
    • Fugh-Berman, A.; Myers, A. Citrus aurantium, an ingredient of dietary supplements marketed for weight loss: Current status of clinical and basic research. Exp. Biol. Med. 2004, 229, 698-704.
    • (2004) Exp. Biol. Med. , vol.229 , pp. 698-704
    • Fugh-Berman, A.1    Myers, A.2
  • 2
    • 27844496880 scopus 로고    scopus 로고
    • Chemical Industry Press: Beijing, China
    • Committee, N.P. Pharmacopoeia of the People's Republic of China; Chemical Industry Press: Beijing, China, 2005; pp. 171-172.
    • (2005) Pharmacopoeia of the People's Republic of China , pp. 171-172
  • 4
    • 24744437314 scopus 로고    scopus 로고
    • Hemodynamic effects of ephedra-free weight-loss supplements in humans
    • Haller, C.A.; Benowitz, N.L.; Jacob, P. Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am. J. Med. 2005, 118, 998-1003.
    • (2005) Am. J. Med. , vol.118 , pp. 998-1003
    • Haller, C.A.1    Benowitz, N.L.2    Jacob, P.3
  • 5
    • 82255179053 scopus 로고    scopus 로고
    • Simultaneous quantification of polymethoxylated flavones and coumarins in Fructus aurantii and Fructus aurantii immaturus using HPLC-ESI-MS/MS
    • Chen, H.; Zhang, W.; Yuan, J.; Li, Y.; Yang, S.; Yang, W. Simultaneous quantification of polymethoxylated flavones and coumarins in Fructus aurantii and Fructus aurantii immaturus using HPLC-ESI-MS/MS. J. Pharm. Biomed. 2012, 59, 90-95.
    • (2012) J. Pharm. Biomed. , vol.59 , pp. 90-95
    • Chen, H.1    Zhang, W.2    Yuan, J.3    Li, Y.4    Yang, S.5    Yang, W.6
  • 6
    • 79955463297 scopus 로고    scopus 로고
    • Recent advances on HPLC/MS in medicinal plant analysis
    • Steinmann, D.; Ganzera, M. Recent advances on HPLC/MS in medicinal plant analysis. J. Pharm. Biomed. 2011, 55, 744-757.
    • (2011) J. Pharm. Biomed. , vol.55 , pp. 744-757
    • Steinmann, D.1    Ganzera, M.2
  • 7
    • 65649092618 scopus 로고    scopus 로고
    • UPLC/Q-TOFMS/MS as a powerful technique for rapid identification of polymethoxylated flavones in Fructus aurantii
    • Zhou, D.; Zhang, X.; Xu, Q.; Xue, X.; Zhang, F.; Liang, X. UPLC/Q-TOFMS/MS as a powerful technique for rapid identification of polymethoxylated flavones in Fructus aurantii. J. Pharm. Biomed. 2009, 50, 2-8.
    • (2009) J. Pharm. Biomed. , vol.50 , pp. 2-8
    • Zhou, D.1    Zhang, X.2    Xu, Q.3    Xue, X.4    Zhang, F.5    Liang, X.6
  • 8
    • 33947433188 scopus 로고    scopus 로고
    • Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry
    • Zhou, D.; Chen, D.; Xu, Q.; Xue, X.; Zhang, F.; Liang, X. Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry. J. Pharm. Biomed. 2007, 43, 1692-1699.
    • (2007) J. Pharm. Biomed. , vol.43 , pp. 1692-1699
    • Zhou, D.1    Chen, D.2    Xu, Q.3    Xue, X.4    Zhang, F.5    Liang, X.6
  • 9
    • 84862786025 scopus 로고    scopus 로고
    • Identification of antioxidants in Fructus aurantii and its quality evaluation using a new on-line combination of analytical techniques
    • Lin, Z.; Wang, H.; Xu, Y.; Dong, J.; Hashi, Y.; Chen, S. Identification of antioxidants in Fructus aurantii and its quality evaluation using a new on-line combination of analytical techniques. Food Chem. 2012, 134, 1181-1191.
    • (2012) Food Chem. , vol.134 , pp. 1181-1191
    • Lin, Z.1    Wang, H.2    Xu, Y.3    Dong, J.4    Hashi, Y.5    Chen, S.6
  • 10
    • 0142060124 scopus 로고    scopus 로고
    • Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line
    • Sakata, K.; Hirose, Y.; Qiao, Z.; Tanaka, T.; Mori, H. Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line. Cancer Lett. 2003, 199, 139-145.
    • (2003) Cancer Lett. , vol.199 , pp. 139-145
    • Sakata, K.1    Hirose, Y.2    Qiao, Z.3    Tanaka, T.4    Mori, H.5
  • 11
    • 84897379381 scopus 로고    scopus 로고
    • Structural characterization and antioxidant activities of polysaccharides from Citrus aurantium L.
    • Wang, Q.H.; Shu, Z.P.; Xu, B.Q.; Xing, N.; Jiao, W.J.; Yang, B.Y.; Kuang, H.X. Structural characterization and antioxidant activities of polysaccharides from Citrus aurantium L. Int. J. Biol. Macromol. 2014, 67, 112-123.
    • (2014) Int. J. Biol. Macromol. , vol.67 , pp. 112-123
    • Wang, Q.H.1    Shu, Z.P.2    Xu, B.Q.3    Xing, N.4    Jiao, W.J.5    Yang, B.Y.6    Kuang, H.X.7
  • 12
    • 0035667114 scopus 로고    scopus 로고
    • Chemistry and pharmacology of the Citrus bioflavonoid hesperidin
    • Garg, A.; Garg, S.; Zaneveld, L.; Singla, A.K. Chemistry and pharmacology of the Citrus bioflavonoid hesperidin. Phytother. Res. 2001, 15, 655-669.
    • (2001) Phytother. Res. , vol.15 , pp. 655-669
    • Garg, A.1    Garg, S.2    Zaneveld, L.3    Singla, A.K.4
  • 13
    • 33646040117 scopus 로고    scopus 로고
    • Antagonistic effects of nobiletin, a polymethoxyflavonoid, on eosinophilic airway inflammation of asthmatic rats and relevant mechanisms
    • Wu, Y.Q.; Zhou, C.H.; Tao, J.; Li, S.N. Antagonistic effects of nobiletin, a polymethoxyflavonoid, on eosinophilic airway inflammation of asthmatic rats and relevant mechanisms. Life Sci. 2006, 78, 2689-2696.
    • (2006) Life Sci. , vol.78 , pp. 2689-2696
    • Wu, Y.Q.1    Zhou, C.H.2    Tao, J.3    Li, S.N.4
  • 15
    • 33644966757 scopus 로고    scopus 로고
    • Evaluation of the anti-allergic activity of Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen
    • Kobayashi, S.; Tanabe, S. Evaluation of the anti-allergic activity of Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen. Int. J. Mol. Med. 2006, 17, 511-515.
    • (2006) Int. J. Mol. Med. , vol.17 , pp. 511-515
    • Kobayashi, S.1    Tanabe, S.2
  • 16
    • 33745769794 scopus 로고    scopus 로고
    • Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocylokines in fructose-induced insulin resistant hamsters
    • Li, R.W.; Theriault, A.G.; Au, K.; Douglas, T.D.; Casaschi, A.; Kurowska, E.M.; Mukherjee, R. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocylokines in fructose-induced insulin resistant hamsters. Life Sci. 2006, 79, 365-373.
    • (2006) Life Sci. , vol.79 , pp. 365-373
    • Li, R.W.1    Theriault, A.G.2    Au, K.3    Douglas, T.D.4    Casaschi, A.5    Kurowska, E.M.6    Mukherjee, R.7
  • 17
    • 84994530859 scopus 로고    scopus 로고
    • Mechanism underlying the antidepressant effect of Fructus aurantii
    • Xu, Y.; Feng, J. Mechanism underlying the antidepressant effect of Fructus aurantii. Chin. J. Pharmacol. Ther. 2013, 1086-1092.
    • (2013) Chin. J. Pharmacol. Ther. , pp. 1086-1092
    • Xu, Y.1    Feng, J.2
  • 18
    • 77954860465 scopus 로고    scopus 로고
    • Application in clinic and research advances of ChaiHu-Shu-Gan-San
    • Zhang, H.; Zou, Z. Application in clinic and research advances of ChaiHu-Shu-Gan-San. Lishizhen Med. Mater. Med. Res. 2007, 1234-1236.
    • (2007) Lishizhen Med. Mater. Med. Res. , pp. 1234-1236
    • Zhang, H.1    Zou, Z.2
  • 19
    • 84877312920 scopus 로고    scopus 로고
    • Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San
    • Jia, H.; Su, Z.; Long, W.; Liu, Y.; Chang, X.; Zhang, H.; Ding, G.; Feng, Y.; Cai, D.; Zou, Z. Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San. Evid. Based Complement. Altern. Med. 2013, 2013, 487158, doi:10.1155/2013/487158.
    • (2013) Evid. Based Complement. Altern. Med. , vol.2013 , pp. 487158
    • Jia, H.1    Su, Z.2    Long, W.3    Liu, Y.4    Chang, X.5    Zhang, H.6    Ding, G.7    Feng, Y.8    Cai, D.9    Zou, Z.10
  • 20
    • 76149116199 scopus 로고    scopus 로고
    • Application of an efficient strategy based on MAE, HPLC-DAD-MS/MS and HSCCC for the rapid extraction, identification, separation and purification of flavonoids from Fructus Aurantii Immaturus
    • Wang, C.; Pan, Y.; Fan, G.; Chai, Y.; Wu, Y. Application of an efficient strategy based on MAE, HPLC-DAD-MS/MS and HSCCC for the rapid extraction, identification, separation and purification of flavonoids from Fructus Aurantii Immaturus. Biomed. Chromatogr. 2010, 24, 235-244.
    • (2010) Biomed. Chromatogr. , vol.24 , pp. 235-244
    • Wang, C.1    Pan, Y.2    Fan, G.3    Chai, Y.4    Wu, Y.5
  • 21
    • 0026310484 scopus 로고
    • Structures of New Cyclic Peptides in Young Unshiu (Citrus unshiu Marcov.), Orange (Citrus sinensis Osbeck.) Peelings
    • Matsubara, Y. Structures of New Cyclic Peptides in Young Unshiu (Citrus unshiu Marcov.), Orange (Citrus sinensis Osbeck.) Peelings. Agric. Biol. Chem. 1991, 55, 2923-2929.
    • (1991) Agric. Biol. Chem. , vol.55 , pp. 2923-2929
    • Matsubara, Y.1
  • 23
    • 84928751214 scopus 로고    scopus 로고
    • Cyclopeptides from Immature Fruits of Citrus aurantium
    • Peng, W.; Tan, N. Cyclopeptides from Immature Fruits of Citrus aurantium. Nat. Prod. Res. Dev. 2014, 26, 1416-1420.
    • (2014) Nat. Prod. Res. Dev. , vol.26 , pp. 1416-1420
    • Peng, W.1    Tan, N.2
  • 24
    • 34548526049 scopus 로고    scopus 로고
    • Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice
    • Peng, W.; Lo, K.; Lee, Y.; Hung, T.; Lin, Y. Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci. 2007, 81, 933-938.
    • (2007) Life Sci. , vol.81 , pp. 933-938
    • Peng, W.1    Lo, K.2    Lee, Y.3    Hung, T.4    Lin, Y.5
  • 25
    • 33747191382 scopus 로고    scopus 로고
    • Neuroprotective effects of agmatine against cell damage caused by glucocorticoids in cultures rat hippocampal neurons
    • Zhu, M.Y.; Wang, W.P.; Bissette, G. Neuroprotective effects of agmatine against cell damage caused by glucocorticoids in cultures rat hippocampal neurons. Neuroscience 2006, 141, 2019-2027.
    • (2006) Neuroscience , vol.141 , pp. 2019-2027
    • Zhu, M.Y.1    Wang, W.P.2    Bissette, G.3
  • 26
    • 84864724396 scopus 로고    scopus 로고
    • Protective Effects of Piperine Against Corticosterone-Induced Neurotoxicity in PC12 Cells
    • Mao, Q.; Huang, Z.; Ip, S.; Xian, Y.; Che, C. Protective Effects of Piperine Against Corticosterone-Induced Neurotoxicity in PC12 Cells. Cell. Mol. Neurobiol. 2012, 32, 531-537.
    • (2012) Cell. Mol. Neurobiol. , vol.32 , pp. 531-537
    • Mao, Q.1    Huang, Z.2    Ip, S.3    Xian, Y.4    Che, C.5
  • 27
    • 84879095239 scopus 로고    scopus 로고
    • Natural polyphenols in the management of major depression
    • Pathak, L.; Agrawal, Y.; Dhir, A. Natural polyphenols in the management of major depression. Expert Opin. Investig. Drugs 2013, 22, 863-880.
    • (2013) Expert Opin. Investig. Drugs , vol.22 , pp. 863-880
    • Pathak, L.1    Agrawal, Y.2    Dhir, A.3
  • 29
    • 84898954223 scopus 로고    scopus 로고
    • Hesperidin exerts antidepressant-like effects in acute and chronic treatments in mice: Possible role of L-arginine-NO-cGMP pathway and BDNF levels
    • Donato, F.; de Gomes, M.G.; Goes, A.; Borges, C.; Del Fabbro, L.; Antunes, M.S.; Souza, L.C.; Boeira, S.P.; Jesse, C.R. Hesperidin exerts antidepressant-like effects in acute and chronic treatments in mice: Possible role of L-arginine-NO-cGMP pathway and BDNF levels. Brain Res. Bull. 2014, 104, 19-26.
    • (2014) Brain Res. Bull. , vol.104 , pp. 19-26
    • Donato, F.1    De Gomes, M.G.2    Goes, A.3    Borges, C.4    Del Fabbro, L.5    Antunes, M.S.6    Souza, L.C.7    Boeira, S.P.8    Jesse, C.R.9
  • 30
    • 78049500586 scopus 로고    scopus 로고
    • Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin
    • Yi, L.T.; Xu, H.L.; Feng, J.; Zhan, X.; Zhou, L.P.; Cui, C.C. Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin. Physiol. Behav. 2011, 102, 1-6.
    • (2011) Physiol. Behav. , vol.102 , pp. 1-6
    • Yi, L.T.1    Xu, H.L.2    Feng, J.3    Zhan, X.4    Zhou, L.P.5    Cui, C.C.6
  • 31
    • 79953226613 scopus 로고    scopus 로고
    • Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats
    • Su, Z.; Li, S.; Zou, G.; Yu, C.; Sun, Y.; Zhang, H.; Gu, Y.; Zou, Z. Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. J. Pharm. Biomed. 2011, 55, 533-539.
    • (2011) J. Pharm. Biomed. , vol.55 , pp. 533-539
    • Su, Z.1    Li, S.2    Zou, G.3    Yu, C.4    Sun, Y.5    Zhang, H.6    Gu, Y.7    Zou, Z.8
  • 32
    • 0017651126 scopus 로고
    • Behavioral despair in mice: A primary screening test for antidepressants
    • Porsolt, R.D.; Bertin, A.; Jalfre, M. Behavioral despair in mice: A primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977, 229, 327-336.
    • (1977) Arch. Int. Pharmacodyn. Ther. , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 33
    • 0021990491 scopus 로고
    • The tail suspension test: A new method for screening antidepressants in mice
    • Steru, L.; Chermat, R.; Thierry, B.; Simon, P. The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacology 1985, 85, 367-370.
    • (1985) Psychopharmacology , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 34
    • 60349106599 scopus 로고    scopus 로고
    • Curcumin Protects PC12 Cells from Corticosterone-Induced Cytotoxicity: Possible Involvement of the ERK1/2 Pathway
    • Gao, M.; Zhou, H.; Li, X. Curcumin Protects PC12 Cells from Corticosterone-Induced Cytotoxicity: Possible Involvement of the ERK1/2 Pathway. Basic Clin. Pharmacol. 2009, 104, 236-240.
    • (2009) Basic Clin. Pharmacol. , vol.104 , pp. 236-240
    • Gao, M.1    Zhou, H.2    Li, X.3


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