-
1
-
-
77951854270
-
Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
-
Caspi A, Hariri AR, Holmes A, et al. Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010;167:509-27.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 509-527
-
-
Caspi, A.1
Hariri, A.R.2
Holmes, A.3
-
2
-
-
38349150151
-
The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis
-
Uher R, McGuffin P. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry 2008;13:131-46.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 131-146
-
-
Uher, R.1
McGuffin, P.2
-
3
-
-
84861459607
-
Bdnf val66met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects
-
Gerritsen L, Tendolkar I, Franke B, et al. BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects. Mol Psychiatry 2012; 17:597-603.
-
Mol Psychiatry 2012;
, vol.17
, pp. 597-603
-
-
Gerritsen, L.1
Tendolkar, I.2
Franke, B.3
-
4
-
-
79952282659
-
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of bdnf val66met
-
Elzinga BM, Molendijk ML, Oude Voshaar RC, et al. The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met. Psychopharmacology (Berl) 2011;214:319-28.
-
(2011)
Psychopharmacology (Berl)
, vol.214
, pp. 319-328
-
-
Elzinga, B.M.1
Molendijk, M.L.2
Oude Voshaar, R.C.3
-
5
-
-
84882851088
-
Childhood emotional environment and self-injurious behaviors: The moderating role of the bdnf val66met polymorphism
-
Bresin K, Sima Finy M, Verona E. Childhood emotional environment and self-injurious behaviors: the moderating role of the BDNF Val66Met polymorphism. J Affect Disord 2013;150;594-600.
-
(2013)
J Affect Disord
, vol.150
, pp. 594-600
-
-
Bresin, K.1
Sima Finy, M.2
Verona, E.3
-
6
-
-
67649964222
-
Early adversity and 5-htt/ bdnf genes: New evidence of gene-environment interactions on depressive symptoms in a general population
-
Aguilera M, Arias B, Wichers M, et al. Early adversity and 5-HTT/ BDNF genes: new evidence of gene-environment interactions on depressive symptoms in a general population. Psychol Med 2009; 39:1425-32.
-
Psychol Med 2009;
, vol.39
, pp. 1425-1432
-
-
Aguilera, M.1
Arias, B.2
Wichers, M.3
-
7
-
-
79958112490
-
Childhood adversity interacts separately with 5-httlpr and bdnf to predict lifetime depression diagnosis
-
Carver CS, Johnson SL, Joormann J, et al. Childhood adversity interacts separately with 5-HTTLPR and BDNF to predict lifetime depression diagnosis. J Affect Disord 2011;132:89-93.
-
(2011)
J Affect Disord
, vol.132
, pp. 89-93
-
-
Carver, C.S.1
Johnson, S.L.2
Joormann, J.3
-
8
-
-
84884284039
-
Three-way interaction effect of 5-httlpr, bdnf val66met, and childhood adversity on depression: A replication study
-
Comasco E, Aslund C, Oreland L, et al. Three-way interaction effect of 5-HTTLPR, BDNF Val66Met, and childhood adversity on depression: a replication study. Eur Neuropsychopharmacol 2013; 23:1300-6.
-
Eur Neuropsychopharmacol 2013;
, vol.23
, pp. 1300-1306
-
-
Comasco, E.1
Aslund, C.2
Oreland, L.3
-
9
-
-
36549042458
-
Interaction between bdnf and serotonin: Role in mood disorders
-
Martinowich K, Lu B. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology 2008;33:73-83.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 73-83
-
-
Martinowich, K.1
Lu, B.2
-
10
-
-
45549100295
-
Evidence of biologic epistasis between bdnf and slc6a4 and implications for depression
-
Pezawas L, Meyer-Lindenberg A, Goldman AL, et al. Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Mol Psychiatry 2008;13:709-16.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 709-716
-
-
Pezawas, L.1
Meyer-Lindenberg, A.2
Goldman, A.L.3
-
11
-
-
14844298782
-
Is mood chemistry?
-
Castrén E. Is mood chemistry? Nat Rev Neurosci 2005;6:241-6.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 241-246
-
-
Castrén, E.1
-
12
-
-
21244493178
-
Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: Tianeptine
-
McEwen BS, Olie JP. Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine. Mol Psychiatry 2005;10:525-37.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 525-537
-
-
McEwen, B.S.1
Olie, J.P.2
-
13
-
-
34548672570
-
Response to lithium prophylaxis: Interaction between serotonin transporter and bdnf genes
-
Rybakowski JK, Suwalska A, Skibinska M, et al. Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes. Am J Med Genet B Neuropsychiatr Genet 2007;144B:820-3.
-
(2007)
Am J Med Genet B Neuropsychiatr Genet
, vol.144B
, pp. 820-823
-
-
Rybakowski, J.K.1
Suwalska, A.2
Skibinska, M.3
-
14
-
-
84855354000
-
Genetic epistasis between the brain-derived neurotrophic factor val66met polymorphism and the 5-htt promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse
-
Grabe HJ, Schwahn C, Mahler J, et al. Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse. Prog Neuropsychopharmacol Biol Psychiatry 2012;36:264-70.
-
(2012)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.36
, pp. 264-270
-
-
Grabe, H.J.1
Schwahn, C.2
Mahler, J.3
-
15
-
-
34548021027
-
Interactions between life stressors and susceptibility genes (5-httlpr and bdnf) on depression in korean elders
-
Kim JM, Stewart R, Kim SW, et al. Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders. Biol Psychiatry 2007;62:423-8.
-
(2007)
Biol Psychiatry
, vol.62
, pp. 423-428
-
-
Kim, J.M.1
Stewart, R.2
Kim, S.W.3
-
16
-
-
37849022761
-
The bdnf val(66)met x 5-httlpr x child adversity interaction and depressive symptoms: An attempt at replication
-
Wichers M, Kenis G, Jacobs N, et al. The BDNF Val(66)Met x 5-HTTLPR x child adversity interaction and depressive symptoms: an attempt at replication. Am J Med Genet B Neuropsychiatr Genet 2008;147B:120-3.
-
(2008)
Am J Med Genet B Neuropsychiatr Genet
, vol.147B
, pp. 120-123
-
-
Wichers, M.1
Kenis, G.2
Jacobs, N.3
-
17
-
-
84860643625
-
The contribution of bdnf and 5-htt polymorphisms and early life stress to the heterogeneity of major depressive disorder: A preliminary study
-
Quinn CR, Dobson-Stone C, Outhred T, et al. The contribution of BDNF and 5-HTT polymorphisms and early life stress to the heterogeneity of major depressive disorder: a preliminary study. Aust N Z J Psychiatry 2012;46:55-63.
-
(2012)
Aust N Z J Psychiatry
, vol.46
, pp. 55-63
-
-
Quinn, C.R.1
Dobson-Stone, C.2
Outhred, T.3
-
18
-
-
84875158172
-
Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems — a longitudinal study
-
Agnafors S, Comasco E, Bladh M, et al. Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems — a longitudinal study. Child Adolesc Psychiatry Ment Health 2013;7:10.
-
(2013)
Child Adolesc Psychiatry Ment Health
, vol.7
, pp. 10
-
-
Agnafors, S.1
Comasco, E.2
Bladh, M.3
-
19
-
-
77954214296
-
Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: The trails study
-
Nederhof E, Bouma EM, Oldehinkel AJ, et al. Interaction between childhood adversity, brain-derived neurotrophic factor Val/Met and serotonin transporter promoter polymorphism on depression: the TRAILS study. Biol Psychiatry 2010;68:209-12.
-
(2010)
Biol Psychiatry
, vol.68
, pp. 209-212
-
-
Nederhof, E.1
Bouma, E.M.2
Oldehinkel, A.J.3
-
20
-
-
33645337891
-
Brain-derived neurotrophic factor-5-httlpr gene interactions and environmental modifiers of depression in children
-
Kaufman J, Yang BZ, Douglas-Palumberi H, et al. Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry 2006;59:673-80.
-
(2006)
Biol Psychiatry
, vol.59
, pp. 673-680
-
-
Kaufman, J.1
Yang, B.Z.2
Douglas-Palumberi, H.3
-
21
-
-
33244458699
-
Prediction of depression in european general practice attendees: The predict study
-
King M, Weich S, Torres-Gonzalez F, et al. Prediction of depression in European general practice attendees: the PREDICT study. BMC Public Health 2006;6:6.
-
(2006)
BMC Public Health
, vol.6
, pp. 6
-
-
King, M.1
Weich, S.2
Torres-Gonzalez, F.3
-
22
-
-
50849085432
-
Predicting the onset and persistence of episodes of depression in primary health care. The predictd-spain study: Methodology
-
Bellón JA, Moreno-Kustner B, Torres-Gonzalez F, et al. Predicting the onset and persistence of episodes of depression in primary health care. The predictD-Spain study: methodology. BMC Public Health 2008;8:256.
-
(2008)
BMC Public Health
, vol.8
, pp. 256
-
-
Bellón, J.A.1
Moreno-Kustner, B.2
Torres-Gonzalez, F.3
-
23
-
-
33845410256
-
The 5-httlpr s/s genotype at the serotonin transporter gene (slc6a4) increases the risk for depression in a large cohort of primary care attendees: The predict-gene study
-
Cervilla JA, Rivera M, Molina E, et al. The 5-HTTLPR s/s genotype at the serotonin transporter gene (SLC6A4) increases the risk for depression in a large cohort of primary care attendees: the PREDICT-gene study. Am J Med Genet B Neuropsychiatr Genet 2006; 141B:912-7.
-
Am J Med Genet B Neuropsychiatr Genet 2006;
, vol.141B
, pp. 912-917
-
-
Cervilla, J.A.1
Rivera, M.2
Molina, E.3
-
24
-
-
50849103187
-
Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: The predictd study
-
King M, Walker C, Levy G, et al. Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: the PredictD study. Arch Gen Psychiatry 2008;65:1368-76.
-
(2008)
Arch Gen Psychiatry
, vol.65
, pp. 1368-1376
-
-
King, M.1
Walker, C.2
Levy, G.3
-
25
-
-
80054943784
-
Predicting the onset of major depression in primary care: International validation of a risk prediction algorithm from spain
-
Bellón JA, de Dios Luna J, King M, et al. Predicting the onset of major depression in primary care: international validation of a risk prediction algorithm from Spain. Psychol Med 2011;41:2075-88.
-
(2011)
Psychol Med
, vol.41
, pp. 2075-2088
-
-
Bellón, J.A.1
De Dios Luna, J.2
King, M.3
-
26
-
-
77957269726
-
Psychosocial and sociodemographic predictors of attrition in a longitudinal study of major depression in primary care: The predictd-spain study
-
Bellón JA, Luna JD, Moreno-Kustner B, et al. Psychosocial and sociodemographic predictors of attrition in a longitudinal study of major depression in primary care: the predictD-Spain study. J Epidemiol Community Health 2010;64:874-84.
-
(2010)
J Epidemiol Community Health
, vol.64
, pp. 874-884
-
-
Bellón, J.A.1
Luna, J.D.2
Moreno-Kustner, B.3
-
27
-
-
0024202654
-
The composite international diagnostic interview. An epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures
-
Robins LN, Wing J, Wittchen HU, et al. The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry 1988;45:1069-77.
-
(1988)
Arch Gen Psychiatry
, vol.45
, pp. 1069-1077
-
-
Robins, L.N.1
Wing, J.2
Wittchen, H.U.3
-
28
-
-
0029097111
-
Initial reliability and validity of the childhood trauma interview: A new multidimensional measure of childhood interpersonal trauma
-
Fink LA, Bernstein D, Handelsman L, et al. Initial reliability and validity of the childhood trauma interview: a new multidimensional measure of childhood interpersonal trauma. Am J Psychiatry 1995;152:1329-35.
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1329-1335
-
-
Fink, L.A.1
Bernstein, D.2
Handelsman, L.3
-
29
-
-
0037293191
-
Development and validation of a brief screening version of the childhood trauma questionnaire
-
Bernstein DP, Stein JA, Newcomb MD, et al. Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child Abuse Negl 2003;27:169-90.
-
(2003)
Child Abuse Negl
, vol.27
, pp. 169-190
-
-
Bernstein, D.P.1
Stein, J.A.2
Newcomb, M.D.3
-
30
-
-
33646072813
-
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
-
Hu XZ, Lipsky RH, Zhu G, et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 2006;78:815-26.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 815-826
-
-
Hu, X.Z.1
Lipsky, R.H.2
Zhu, G.3
-
31
-
-
0034533519
-
Wilkinson g. Gender differences in depression. critical review
-
Piccinelli M, Wilkinson G. Gender differences in depression. Critical review. Br J Psychiatry 2000;177:486-92.
-
(2000)
Br J Psychiatry
, vol.177
, pp. 486-492
-
-
Piccinelli, M.1
-
32
-
-
0016355478
-
A new look at the statistical model identification
-
Akaike H. A new look at the statistical model identification. IEEE Trans Automat Contr 1974;19:716-23.
-
(1974)
IEEE Trans Automat Contr
, vol.19
, pp. 716-723
-
-
Akaike, H.1
-
34
-
-
0031706256
-
Variability in the serotonin transporter gene and increased risk for major depression with melancholia
-
Gutiérrez B, Pintor L, Gasto C, et al. Variability in the serotonin transporter gene and increased risk for major depression with melancholia. Hum Genet 1998;103:319-22.
-
(1998)
Hum Genet
, vol.103
, pp. 319-322
-
-
Gutiérrez, B.1
Pintor, L.2
Gasto, C.3
-
35
-
-
33645799676
-
Genetics of emotional regulation: The role of the serotonin transporter in neural function
-
Hariri AR, Holmes A. Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci 2006; 10:182-91.
-
Trends Cogn Sci 2006;
, vol.10
, pp. 182-191
-
-
Hariri, A.R.1
Holmes, A.2
-
36
-
-
33845309080
-
Serotonin transporter gene variants and behavior: A comprehensive review
-
Serretti A, Calati R, Mandelli L, et al. Serotonin transporter gene variants and behavior: a comprehensive review. Curr Drug Targets 2006;7:1659-69.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 1659-1669
-
-
Serretti, A.1
Calati, R.2
Mandelli, L.3
-
37
-
-
0037462449
-
The bdnf val66met polymorphism affects activity-dependent secretion of bdnf and human memory and hippocampal function
-
Egan MF, Kojima M, Callicott JH, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-69.
-
(2003)
Cell
, vol.112
, pp. 257-269
-
-
Egan, M.F.1
Kojima, M.2
Callicott, J.H.3
-
38
-
-
0038771149
-
Alterations of serum levels of brain-derived neurotrophic factor (bdnf) in depressed patients with or without antidepressants
-
Shimizu E, Hashimoto K, Okamura N, et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003; 54:70-5.
-
Biol Psychiatry 2003;
, vol.54
, pp. 70-75
-
-
Shimizu, E.1
Hashimoto, K.2
Okamura, N.3
-
39
-
-
33745208951
-
A neurotrophic model for stressrelated mood disorders
-
Duman RS, Monteggia LM. A neurotrophic model for stressrelated mood disorders. Biol Psychiatry 2006;59:1116-27.
-
(2006)
Biol Psychiatry
, vol.59
, pp. 1116-1127
-
-
Duman, R.S.1
Monteggia, L.M.2
-
40
-
-
78149267659
-
Variant brain-derived neurotrophic factor val66met endophenotypes: Implications for posttraumatic stress disorder
-
Frielingsdorf H, Bath KG, Soliman F, et al. Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. Ann N Y Acad Sci 2010;1208:150-7.
-
(2010)
Ann N Y Acad Sci
, vol.1208
, pp. 150-157
-
-
Frielingsdorf, H.1
Bath, K.G.2
Soliman, F.3
-
41
-
-
0037310231
-
A bdnf coding variant is associated with the neo personality inventory domain neuroticism, a risk factor for depression
-
Sen S, Nesse RM, Stoltenberg SF, et al. A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression. Neuropsychopharmacology 2003; 28:397-401.
-
Neuropsychopharmacology 2003;
, vol.28
, pp. 397-401
-
-
Sen, S.1
Nesse, R.M.2
Stoltenberg, S.F.3
-
42
-
-
21244432717
-
Association of a functional bdnf polymorphism and anxiety-related personality traits
-
Lang UE, Hellweg R, Kalus P, et al. Association of a functional BDNF polymorphism and anxiety-related personality traits. Psychopharmacology (Berl) 2005;180:95-9.
-
(2005)
Psychopharmacology (Berl)
, vol.180
, pp. 95-99
-
-
Lang, U.E.1
Hellweg, R.2
Kalus, P.3
-
43
-
-
27544495491
-
The val66met coding variant of the brain-derived neurotrophic factor (bdnf) gene does not contribute toward variation in the personality trait neuroticism
-
Willis-Owen SA, Fullerton J, Surtees PG, et al. The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism. Biol Psychiatry 2005;58:738-42.
-
(2005)
Biol Psychiatry
, vol.58
, pp. 738-742
-
-
Willis-Owen, S.A.1
Fullerton, J.2
Surtees, P.G.3
-
44
-
-
33846634095
-
No association between the bdnf val66met polymorphism and mood status in a non-clinical community sample of 7389 older adults
-
Surtees PG, Wainwright NW, Willis-Owen SA, et al. No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults. J Psychiatr Res 2007;41:404-9.
-
(2007)
J Psychiatr Res
, vol.41
, pp. 404-409
-
-
Surtees, P.G.1
Wainwright, N.W.2
Willis-Owen, S.A.3
-
45
-
-
84904561107
-
Additive gene-environment effects on hippocampal structure in healthy humans
-
Rabl U, Meyer BM, Diers K, et al. Additive gene-environment effects on hippocampal structure in healthy humans. J Neurosci 2014; 34:9917-26.
-
J Neurosci 2014;
, vol.34
, pp. 9917-9926
-
-
Rabl, U.1
Meyer, B.M.2
Diers, K.3
-
47
-
-
84871832771
-
How do environments talk to genes?
-
Szyf M. How do environments talk to genes? Nat Neurosci 2013;16:2-4.
-
(2013)
Nat Neurosci
, vol.16
, pp. 2-4
-
-
Szyf, M.1
-
48
-
-
84889584152
-
Gene x environment interaction studies have not properly controlled for potential confounders: The problem and the (simple) solution
-
Keller MC. Gene x environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution. Biol Psychiatry 2014;75:18-24.
-
(2014)
Biol Psychiatry
, vol.75
, pp. 18-24
-
-
Keller, M.C.1
-
49
-
-
84864413139
-
Including known covariates can reduce power to detect genetic effects in case-control studies
-
Pirinen M, Donnelly P, Spencer CC. Including known covariates can reduce power to detect genetic effects in case-control studies. Nat Genet 2012;44:848-51.
-
(2012)
Nat Genet
, vol.44
, pp. 848-851
-
-
Pirinen, M.1
Donnelly, P.2
Spencer, C.C.3
|