Indolicidin targets duplex DNA: Structural and mechanistic insight through a combination of spectroscopy and microscopy

ChemMedChem

Volumn 9, Issue 9, 2014, Pages 2052-2058

  Ghosh, Anirban ^a   Kar, Rajiv Kumar ^a   Jana, Jagannath ^a   Saha, Abhijit ^b   Jana, Batakrishna ^b   Krishnamoorthy, Janarthanan ^c   Kumar, Dinesh ^d   Ghosh, Surajit ^b   Chatterjee, Subhrangsu ^a   Bhunia, Anirban ^a  

^a BOSE INSTITUTE   (India)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^c UNIVERSITY OF MICHIGAN   (United States)

^d Center for Bio Medical Magnetic Resonance Lucknow   (India)

Author keywords

AMP; duplex DNA; indolicidin; molecular dynamics; NMR spectroscopy

Indexed keywords

DOUBLE STRANDED DNA; INDOLICIDIN; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL DNA;

AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; DNA STRUCTURE; DNA SYNTHESIS; DRUG DNA BINDING; FLUORESCENCE MICROSCOPY; FLUORESCENCE SPECTROSCOPY; GENE TARGETING; HYDROGEN BOND; HYDROPHOBICITY; LIGHT SCATTERING; MELTING POINT; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SURFACE PLASMON RESONANCE; ULTRAVIOLET SPECTROSCOPY; BACTERIUM; DRUG EFFECTS; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMOR CELL LINE;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CELL LINE, TUMOR; DNA REPLICATION; DNA, BACTERIAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY;

EID: 84928710946     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201402215     Document Type: Article

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