The generation of antimicrobial peptide activity: A trade-off between charge and aggregation?

Angewandte Chemie - International Edition

Volumn 50, Issue 45, 2011, Pages 10686-10689

  Torrent, Marc ^a   Valle, Javier ^a   Nogués, M Victòria ^b   Boix, Ester ^b   Andreu, David ^a  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

aggregation; amyloids; antimicrobial agents; molecular evolution; peptides

Indexed keywords

AMYLOIDS; ANTI-MICROBIAL ACTIVITY; ANTI-MICROBIAL AGENT; ANTIMICROBIAL PEPTIDE; MOLECULAR EVOLUTION;

GLYCOPROTEINS; MOLECULAR BIOLOGY; PEPTIDES; POLYPEPTIDES;

MICROORGANISMS;

ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; HUMAN; IMMUNOLOGY; MICROCOCCUS LUTEUS; MOLECULAR GENETICS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ESCHERICHIA COLI; HUMANS; MICROCOCCUS LUTEUS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80155128846     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201103589     Document Type: Article

References (25)

1. Y. J. Gordon, E. G. Romanowski, A. M. McDermott, Curr. Eye Res. 2005, 30, 505-515.
2. M. N. Melo, R. Ferre, M. A. Castanho, Nat. Rev. Microbiol. 2009, 7, 245-250.
3. K. Matsuzaki, Biochem. Soc. Trans. 2001, 29, 598-601
4. Y. Shai, Biochim. Biophys. Acta Biomembr. 1999, 1462, 55-70.
5. H. Zhao, R. Sood, A. Jutila, S. Bose, G. Fimland, J. Nissen-Meyer, P. K. Kinnunen, Biochim. Biophys. Acta Biomembr. 2006, 1758, 1461-1474.
6. A. K. Mahalka, P. K. Kinnunen, Biochim. Biophys. Acta Biomembr. 2009, 1788, 1600-1609.
7. A. J. Trexler, M. R. Nilsson, Curr. Protein Pept. Sci. 2007, 8, 537-557.
8. M. R. Nilsson, C. M. Dobson, Biochemistry 2003, 42, 375-382.
9. M. Torrent, F. Odorizzi, M. V. Nogues, E. Boix, Biomacromolecules 2010, 11, 1983-1990.
10. C. Hertel, E. Terzi, N. Hauser, R. Jakob-Rotne, J. Seelig, J. A. Kemp, Proc. Natl. Acad. Sci. USA 1997, 94, 9412-9416
11. H. Zhao, E. K. Tuominen, P. K. Kinnunen, Biochemistry 2004, 43, 10302-10307.
12. M. Stockl, P. Fischer, E. Wanker, A. Herrmann, J. Mol. Biol. 2008, 375, 1394-1404.
13. E. E. Ambroggio, D. H. Kim, F. Separovic, C. J. Barrow, K. J. Barnham, L. A. Bagatolli, G. D. Fidelio, Biophys. J. 2005, 88, 2706-2713.
14. S. J. Soscia, J. E. Kirby, K. J. Washicosky, S. M. Tucker, M. Ingelsson, B. Hyman, M. A. Burton, L. E. Goldstein, S. Duong, R. E. Tanzi, R. D. Moir, PLoS One 2010, 5, e 9505.
15. J. Miklossy, J. Alzheimers Dis. 2008, 13, 381-391.
16. E. Monsellier, M. Ramazzotti, N. Taddei, F. Chiti, PLoS Comput. Biol. 2008, 4, e 1000199.
17. A. P. Pawar, K. F. Dubay, J. Zurdo, F. Chiti, M. Vendruscolo, C. M. Dobson, J. Mol. Biol. 2005, 350, 379-392.
18. M. Torrent, V. M. Nogues, E. Boix, BMC Bioinf. 2009, 10, 373.
19. O. Conchillo-Sole, N. S. de Groot, F. X. Aviles, J. Vendrell, X. Daura, S. Ventura, BMC Bioinf. 2007, 8, 65.
20. M. R. Yeaman, N. Y. Yount, Nat. Rev. Microbiol. 2007, 5, 727-740.
21. P. Nicolas, FEBS J. 2009, 276, 6483-6496.
22. K. A. Brogden, Nat. Rev. Microbiol. 2005, 3, 238-250.
23. S. Lata, B. K. Sharma, G. P. Raghava, BMC Bioinf. 2007, 8, 263.
24. S. Thomas, S. Karnik, R. S. Barai, V. K. Jayaraman, S. Idicula-Thomas, Nucleic Acids Res. 2010, 38, D 774-D 780.
25. R. Sood, P. K. Kinnunen, Biochim. Biophys. Acta Biomembr. 2008, 1778, 1460-1466.