Studies on Lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides

Journal of Biological Chemistry

Volumn 286, Issue 24, 2011, Pages 21266-21276

  Zweytick, Dagmar ^a   Deutsch, Günter ^a   Andrä, Jörg ^b   Blondelle, Sylvie E ^c,f   Vollmer, Ekkehard ^b   Jerala, Roman ^d,e   Lohner, Karl ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b RESEARCH CENTER BORSTEL   (Germany)

^c TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^d NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^e UNIVERSITY OF LJUBLJANA   (Slovenia)

^f BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-MICROBIAL ACTIVITY; BACTERIAL MEMBRANES; BI-LAYER; CELL LYSIS; CHARGED BILAYERS; DIFFERENT EFFECTS; E. COLI; GRAM-NEGATIVE BACTERIA; HETEROGENEOUS DOMAINS; HIGHER-DEGREE; HYDROPHOBIC AMINO ACIDS; INNER MEMBRANES; LACTOFERRICIN; LIPID DOMAINS; LIPID VESICLES; LIPOPOLYSACCHARIDES; MEMBRANE CURVATURE; MEMBRANE PERMEABILIZATION; MEMBRANE-ACTIVE PEPTIDES; MINIMAL INHIBITORY CONCENTRATION; MOLECULAR LEVELS; N-TERMINALS; NEUTRAL LIPID; OUTER MEMBRANE; PACKING DEFECT; POLAR RESIDUES;

ACYLATION; AMINO ACIDS; BACTERIA; BACTERIOLOGY; ESCHERICHIA COLI; HYDROPHOBICITY; LIPID BILAYERS; MEMBRANES; TRANSMISSION ELECTRON MICROSCOPY;

PEPTIDES;

ESCHERICHIA COLI PROTEIN; GLYCINE; ISOLEUCINE; LACTOFERRICIN; LIPOSOME; LYSINE; VALINE;

ACYLATION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL VIABILITY; CALORIMETRY; CYTOLYSIS; ESCHERICHIA COLI; HYDROPHOBICITY; LIPID VESICLE; MEMBRANE PERMEABILITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; STATIC ELECTRICITY; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY;

ACYLATION; ANTIMICROBIAL CATIONIC PEPTIDES; BIOPHYSICS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL MEMBRANE; ESCHERICHIA COLI; HEMOLYSIS; HUMANS; LACTOFERRIN; LEUKOCYTES, MONONUCLEAR; LIPOSOMES; MICROSCOPY, ELECTRON, TRANSMISSION; PEPTIDES; PHOSPHOLIPIDS; PROTEIN STRUCTURE, TERTIARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 79958756074     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.195412     Document Type: Article

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