Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations

Nanoscale Research Letters

Volumn 9, Issue 1, 2014, Pages

  Ye, Meiling ^a   Tang, Ling ^a   Luo, Mengjun ^b   Zhou, Jing ^a   Guo, Bin ^a   Liu, Yangyuan ^a   Chen, Bo ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

^b Yiyang Medical College   (China)

Author keywords

Cytochrome P450; Gold nanoparticle; Incubation; Inhibition; Microsome; Nanoprecipitation

Indexed keywords

DRUG DELIVERY; DRUG DOSAGE; ENZYME INHIBITION; FIBER OPTIC SENSORS; ISOENZYMES; LIGHT SCATTERING; METABOLISM; METAL NANOPARTICLES; PARTICLE SIZE; STABILIZATION;

CYTOCHROME P450; INCUBATION; INTEGRAL MEMBRANE PROTEINS; MICROSOME; NANO PRECIPITATIONS; NICOTINAMIDE ADENINE DINUCLEOTIDES; PARTICLE CHARACTERISTICS; ZETA POTENTIAL MEASUREMENTS;

GOLD NANOPARTICLES;

EID: 84928672665     PISSN: 19317573     EISSN: 1556276X     Source Type: Journal    
DOI: 10.1186/1556-276X-9-642     Document Type: Article

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