-
1
-
-
84928906170
-
Curcumin and ω-3 fatty acids potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production
-
submitted
-
Halder, R.; Almasi, A.; Sagong, B.; Leung, J.; Jewett, A.; Fiala, M. Curcumin and ω-3 fatty acids potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production. Front. Physiol. 2015, submitted.
-
(2015)
Front. Physiol.
-
-
Halder, R.1
Almasi, A.2
Sagong, B.3
Leung, J.4
Jewett, A.5
Fiala, M.6
-
2
-
-
30044446136
-
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
-
Aggarwal, S.; Ichikawa, H.; Takada, Y.; Sandur, S.K.; Shishodia, S.; Aggarwal, B.B. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol. Pharmacol. 2006, 69, 195-206.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 195-206
-
-
Aggarwal, S.1
Ichikawa, H.2
Takada, Y.3
Sandur, S.K.4
Shishodia, S.5
Aggarwal, B.B.6
-
3
-
-
58149202128
-
Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
-
Baud, V.; Karin, M. Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat. Rev. Drug Discov. 2009, 8, 33-40.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 33-40
-
-
Baud, V.1
Karin, M.2
-
4
-
-
27744548150
-
Effects of nuclear factor-κB inhibitors and its implication on natural killer T-cell lymphoma cells
-
Kim, K.; Ryu, K.; Ko, Y.; Park, C. Effects of nuclear factor-κB inhibitors and its implication on natural killer T-cell lymphoma cells. Br. J. Haematol. 2005, 131, 59-66.
-
(2005)
Br. J. Haematol.
, vol.131
, pp. 59-66
-
-
Kim, K.1
Ryu, K.2
Ko, Y.3
Park, C.4
-
5
-
-
84883696280
-
Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice
-
Siddiqui, R.A.; Harvey, K.A.; Walker, C.; Altenburg, J.; Xu, Z.; Terry, C.; Camarillo, I.; Jones-Hall, Y.; Mariash, C. Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice. BMC Cancer 2013, 13, 418.
-
(2013)
BMC Cancer
, vol.13
, pp. 418
-
-
Siddiqui, R.A.1
Harvey, K.A.2
Walker, C.3
Altenburg, J.4
Xu, Z.5
Terry, C.6
Camarillo, I.7
Jones-Hall, Y.8
Mariash, C.9
-
6
-
-
55949119550
-
Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids
-
Swamy, M.V.; Citineni, B.; Patlolla, J.M.R.; Mohammed, A.; Zhang, Y.; Rao, C.V. Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids. Nutr. Cancer 2008, 60, 81-89.
-
(2008)
Nutr. Cancer
, vol.60
, pp. 81-89
-
-
Swamy, M.V.1
Citineni, B.2
Patlolla, J.M.R.3
Mohammed, A.4
Zhang, Y.5
Rao, C.V.6
-
7
-
-
84896702241
-
Role of the immune system in pancreatic cancer progression and immune modulating treatment strategies
-
Sideras, K.; Braat, H.; Kwekkeboom, J.; van Eijck, C.H.; Peppelebosch, M.P.; Sleijfer, S.; Bruno, M. Role of the immune system in pancreatic cancer progression and immune modulating treatment strategies. Cancer Treat Rev. 2014, 40, 513-522.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 513-522
-
-
Sideras, K.1
Braat, H.2
Kwekkeboom, J.3
Van Eijck, C.H.4
Peppelebosch, M.P.5
Sleijfer, S.6
Bruno, M.7
-
8
-
-
33845865825
-
Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
-
Yu, H.; Kortylewski, M.; Pardoll, D. Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment. Nat. Rev. Immunol. 2007, 7, 41-51.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
9
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang, T.; Niu, G.; Kortylewski, M.; Burdelya, L.; Shain, K.; Zhang, S.; Bhattacharya, R.; Gabrilovich, D.; Heller, R.; Coppola, D.; et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat. Med. 2004, 10, 48-54.
-
(2004)
Nat. Med.
, vol.10
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
Burdelya, L.4
Shain, K.5
Zhang, S.6
Bhattacharya, R.7
Gabrilovich, D.8
Heller, R.9
Coppola, D.10
-
10
-
-
0345016388
-
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia
-
Kim, H.Y.; Park, E.J.; Joe, E.-H.; Jou, I. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J. Immunol. 2003, 171, 6072-6079.
-
(2003)
J. Immunol.
, vol.171
, pp. 6072-6079
-
-
Kim, H.Y.1
Park, E.J.2
Joe, E.-H.3
Jou, I.4
-
11
-
-
70349479218
-
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines
-
Bill, M.A.; Bakan, C.; Benson, D.M., Jr.; Fuchs, J.; Young, G.; Lesinski, G.B. Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines. Mol. Cancer Ther. 2009, 8, 2726-2735.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2726-2735
-
-
Bill, M.A.1
Bakan, C.2
Benson, D.M.3
Fuchs, J.4
Young, G.5
Lesinski, G.B.6
-
12
-
-
0031774896
-
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
-
Imada, K.; Bloom, E.T.; Nakajima, H.; Horvath-Arcidiacono, J.A.; Udy, G.B.; Davey, H.W.; Leonard, W.J. Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity. J. Exp. Med. 1998, 188, 2067-2074.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2067-2074
-
-
Imada, K.1
Bloom, E.T.2
Nakajima, H.3
Horvath-Arcidiacono, J.A.4
Udy, G.B.5
Davey, H.W.6
Leonard, W.J.7
-
13
-
-
79959612772
-
A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
-
Kanai, M.; Yoshimura, K.; Asada, M.; Imaizumi, A.; Suzuki, C.; Matsumoto, S.; Nishimura, T.; Mori, Y.; Masui, T.; Kawaguchi, Y.; et al. A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer. Cancer Chemother. Pharmacol. 2011, 68, 157-164.
-
(2011)
Cancer Chemother. Pharmacol.
, vol.68
, pp. 157-164
-
-
Kanai, M.1
Yoshimura, K.2
Asada, M.3
Imaizumi, A.4
Suzuki, C.5
Matsumoto, S.6
Nishimura, T.7
Mori, Y.8
Masui, T.9
Kawaguchi, Y.10
-
14
-
-
41149158492
-
Immunomodulatory effects of curcumin: In-vivo
-
Varalakshmi, C.; Mubarak Ali, A.; Pardhasaradhi, B.V.V.; Srivastava, R.M.; Singh, S.; Khar, A. Immunomodulatory effects of curcumin: In-vivo. Int. Immunopharmacol. 2008, 8, 688-700.
-
(2008)
Int. Immunopharmacol.
, vol.8
, pp. 688-700
-
-
Varalakshmi, C.1
Mubarak Ali, A.2
Pardhasaradhi, B.V.V.3
Srivastava, R.M.4
Singh, S.5
Khar, A.6
-
15
-
-
79953057599
-
Use of curcumin to decrease nitric oxide production during the induction of antitumor responses by IL-2
-
Song, M.Y.; Yim, J.Y.; Yim, J.M.; Kang, I.J.; Rho, H.W.; Kim, H.S.; Yhim, H.Y.; Lee, N.R.; Song, E.K.; Kwak, J.Y.; et al. Use of curcumin to decrease nitric oxide production during the induction of antitumor responses by IL-2. J. Immunother. 2011, 34, 149-164.
-
(2011)
J. Immunother.
, vol.34
, pp. 149-164
-
-
Song, M.Y.1
Yim, J.Y.2
Yim, J.M.3
Kang, I.J.4
Rho, H.W.5
Kim, H.S.6
Yhim, H.Y.7
Lee, N.R.8
Song, E.K.9
Kwak, J.Y.10
-
16
-
-
84890082601
-
Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer
-
Bimonte, S.; Barbieri, A.; Palma, G.; Luciano, A.; Rea, D.; Arra, C. Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer. BioMed Res. Int. 2013, 2013, 810423.
-
(2013)
BioMed Res. Int.
, vol.2013
, pp. 810423
-
-
Bimonte, S.1
Barbieri, A.2
Palma, G.3
Luciano, A.4
Rea, D.5
Arra, C.6
-
17
-
-
51649118928
-
Phase II trial of curcumin in patients with advanced pancreatic cancer
-
Dhillon, N.; Aggarwal, B.B.; Newman, R.A.; Wolff, R.A.; Kunnumakkara, A.B.; Abbruzzese, J.L.; Ng, C.S. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin. Cancer Res. 2008, 14, 4491-4499.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4491-4499
-
-
Dhillon, N.1
Aggarwal, B.B.2
Newman, R.A.3
Wolff, R.A.4
Kunnumakkara, A.B.5
Abbruzzese, J.L.6
Ng, C.S.7
-
18
-
-
77958011209
-
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs
-
Goel, A.; Aggarwal, B.B. Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr. Cancer 2010, 62, 919-930.
-
(2010)
Nutr. Cancer
, vol.62
, pp. 919-930
-
-
Goel, A.1
Aggarwal, B.B.2
-
19
-
-
84888878408
-
Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells
-
Zhou, D.Y.; Zhang, K.; Conney, A.H.; Ding, N.; Cui, X.X.; Wang, H.; Verano, M.; Zhao, S.Q.; Fan, Y.X.; Zheng, X.; et al. Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells. Chem. Pharm. Bull. 2013, 61, 1149-1155.
-
(2013)
Chem. Pharm. Bull.
, vol.61
, pp. 1149-1155
-
-
Zhou, D.Y.1
Zhang, K.2
Conney, A.H.3
Ding, N.4
Cui, X.X.5
Wang, H.6
Verano, M.7
Zhao, S.Q.8
Fan, Y.X.9
Zheng, X.10
-
20
-
-
84866782159
-
Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer
-
Dandawate, P.R.; Vyas, A.; Ahmad, A.; Banerjee, S.; Deshpande, J.; Venkateswara Swamy, K.; Jamadar, A.; Dumhe-Klaire, A.C.; Padhye, S.; Sarkar, F.H. Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer. Pharm. Res. 2012, 29, 1775-1786.
-
(2012)
Pharm. Res.
, vol.29
, pp. 1775-1786
-
-
Dandawate, P.R.1
Vyas, A.2
Ahmad, A.3
Banerjee, S.4
Deshpande, J.5
Venkateswara Swamy, K.6
Jamadar, A.7
Dumhe-Klaire, A.C.8
Padhye, S.9
Sarkar, F.H.10
-
21
-
-
84861637434
-
Synthesis and evaluation of curcumin-related compounds for anticancer activity
-
Wei, X.; Du, Z.-Y.; Zheng, X.; Cui, X.-X.; Conney, A.H.; Zhang, K. Synthesis and evaluation of curcumin-related compounds for anticancer activity. Eur. J. Med. Chem. 2012, 53, 235-245.
-
(2012)
Eur. J. Med. Chem.
, vol.53
, pp. 235-245
-
-
Wei, X.1
Du, Z.-Y.2
Zheng, X.3
Cui, X.-X.4
Conney, A.H.5
Zhang, K.6
-
22
-
-
77955869442
-
Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry
-
Padhye, S.; Chavan, D.; Pandey, S.; Deshpande, J.; Swamy, K.V.; Sarkar, F.H. Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry. Mini. Rev. Med. Chem. 2010, 10, 372-387.
-
(2010)
Mini. Rev. Med. Chem.
, vol.10
, pp. 372-387
-
-
Padhye, S.1
Chavan, D.2
Pandey, S.3
Deshpande, J.4
Swamy, K.V.5
Sarkar, F.H.6
-
23
-
-
33947423447
-
Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b
-
Wang, W.; Edington, H.D.; Rao, U.N.; Jukic, D.M.; Land, S.R.; Ferrone, S.; Kirkwood, J.M. Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b. Clin. Cancer Res. 2007, 13, 1523-1531.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1523-1531
-
-
Wang, W.1
Edington, H.D.2
Rao, U.N.3
Jukic, D.M.4
Land, S.R.5
Ferrone, S.6
Kirkwood, J.M.7
-
24
-
-
77954613878
-
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
-
Bill, M.A.; Fuchs, J.R.; Li, C.; Yui, J.; Bakan, C.; Benson, D.M.; Schwartz, E.B.; Abdelhamid, D.; Lin, J.; Hoyt, D.G.; et al. The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol. Cancer 2010, 9, 165.
-
(2010)
Mol. Cancer
, vol.9
, pp. 165
-
-
Bill, M.A.1
Fuchs, J.R.2
Li, C.3
Yui, J.4
Bakan, C.5
Benson, D.M.6
Schwartz, E.B.7
Abdelhamid, D.8
Lin, J.9
Hoyt, D.G.10
-
25
-
-
84896376445
-
Proresolving lipid mediators and mechanisms in the resolution of acute inflammation
-
Buckley, C.D.; Gilroy, D.W.; Serhan, C.N. Proresolving lipid mediators and mechanisms in the resolution of acute inflammation. Immunity 2014, 40, 315-327.
-
(2014)
Immunity
, vol.40
, pp. 315-327
-
-
Buckley, C.D.1
Gilroy, D.W.2
Serhan, C.N.3
-
26
-
-
33747620742
-
Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids
-
Xia, S.; Lu, Y.; Wang, J.; He, C.; Hong, S.; Serhan, C.N.; Kang, J.X. Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Proc. Natl. Acad. Sci. USA 2006, 103, 12499-12504.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12499-12504
-
-
Xia, S.1
Lu, Y.2
Wang, J.3
He, C.4
Hong, S.5
Serhan, C.N.6
Kang, J.X.7
-
27
-
-
81155152336
-
Regulation of inflammation in cancer by eicosanoids
-
Greene, E.R.; Huang, S.; Serhan, C.N.; Panigrahy, D. Regulation of inflammation in cancer by eicosanoids. Prostaglandins Other Lipid Mediat. 2011, 96, 27-36.
-
(2011)
Prostaglandins Other Lipid Mediat
, vol.96
, pp. 27-36
-
-
Greene, E.R.1
Huang, S.2
Serhan, C.N.3
Panigrahy, D.4
-
28
-
-
79955670124
-
Resolvins and protectins in inflammation resolution
-
Serhan, C.N.; Petasis, N.A. Resolvins and protectins in inflammation resolution. Chem. Rev. 2011, 111, 5922-5943.
-
(2011)
Chem. Rev.
, vol.111
, pp. 5922-5943
-
-
Serhan, C.N.1
Petasis, N.A.2
-
29
-
-
0030035046
-
Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma
-
Lai, P.; Rabinowich, H.; Crowley-Nowick, P.A.; Bell, M.C.; Mantovani, G.; Whiteside, T.L. Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma. Clin. Cancer Res. 1996, 2, 161-173.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 161-173
-
-
Lai, P.1
Rabinowich, H.2
Crowley-Nowick, P.A.3
Bell, M.C.4
Mantovani, G.5
Whiteside, T.L.6
-
30
-
-
78650970845
-
Innate or adaptive immunity? The example of natural killer cells
-
Vivier, E.; Raulet, D.H.; Moretta, A.; Caligiuri, M.A.; Zitvogel, L.; Lanier, L.L.; Yokoyama, W.M.; Ugolini, S. Innate or adaptive immunity? The example of natural killer cells. Science 2011, 331, 44-49.
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
Caligiuri, M.A.4
Zitvogel, L.5
Lanier, L.L.6
Yokoyama, W.M.7
Ugolini, S.8
-
31
-
-
80053469514
-
The two faces of interferon-gamma in cancer
-
Zaidi, M.R.; Merlino, G. The two faces of interferon-gamma in cancer. Clin. Cancer Res. 2011, 17, 6118-6124.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6118-6124
-
-
Zaidi, M.R.1
Merlino, G.2
-
32
-
-
84922571766
-
Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome
-
Serhan, C.N.; Dalli, J.; Colas, R.A.; Winkler, J.W.; Chiang, N. Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome. Biochim. Biophys. Acta 2014, 1851, 397-413.
-
(2014)
Biochim. Biophys. Acta
, vol.1851
, pp. 397-413
-
-
Serhan, C.N.1
Dalli, J.2
Colas, R.A.3
Winkler, J.W.4
Chiang, N.5
|