메뉴 건너뛰기




Volumn 8, Issue 5, 2008, Pages 688-700

Immunomodulatory effects of curcumin: In-vivo

Author keywords

Curcumin; Lymphoproliferation; Macrophages; NK cells; NO; ROS

Indexed keywords

ANTIGEN; CD3 ANTIBODY; CURCUMIN; CYCLOSPORIN A; CYTOKINE; IMMUNOMODULATING AGENT; MITOGENIC AGENT; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

EID: 41149158492     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.01.008     Document Type: Article
Times cited : (116)

References (58)
  • 2
    • 33947429094 scopus 로고    scopus 로고
    • NMR study of the solution structure of curcumin
    • Payton F., Sandusky P., and Alworth W.L. NMR study of the solution structure of curcumin. J Nat Products 70 (2007) 143-146
    • (2007) J Nat Products , vol.70 , pp. 143-146
    • Payton, F.1    Sandusky, P.2    Alworth, W.L.3
  • 3
    • 35148853739 scopus 로고    scopus 로고
    • Curcumin is a modulator of bilayer material properties
    • Ingolfsson H.I., Ii R.E., and Andersen O.S. Curcumin is a modulator of bilayer material properties. Biochemistry 46 (2007) 10384-10391
    • (2007) Biochemistry , vol.46 , pp. 10384-10391
    • Ingolfsson, H.I.1    Ii, R.E.2    Andersen, O.S.3
  • 4
    • 0032534459 scopus 로고    scopus 로고
    • Apoptosis-independent alterations in membrane dynamics induced by curcumin
    • Jaruga E., Sokal A., Chrul S., and Bartosz G. Apoptosis-independent alterations in membrane dynamics induced by curcumin. Exp Cell Res 245 (1998) 303-312
    • (1998) Exp Cell Res , vol.245 , pp. 303-312
    • Jaruga, E.1    Sokal, A.2    Chrul, S.3    Bartosz, G.4
  • 5
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal B.B., and Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 71 (2006) 1397-13421
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-13421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 6
    • 84934436717 scopus 로고    scopus 로고
    • Molecular targets of curcumin
    • Lin J.K. Molecular targets of curcumin. Adv Exp Med Biol 595 (2007) 227-243
    • (2007) Adv Exp Med Biol , vol.595 , pp. 227-243
    • Lin, J.K.1
  • 7
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane)
    • Singh S., and Aggarwal B.B. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane). J Biol Chem 270 (1995) 24995-25000
    • (1995) J Biol Chem , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 8
    • 0035203946 scopus 로고    scopus 로고
    • Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates
    • Khar A., Ali A.M., Pardhasaradhi B.V., Varalakshmi C.H., Anjum R., and Kumari A.L. Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates. Cell Stress Chaperones 6 (2001) 368-376
    • (2001) Cell Stress Chaperones , vol.6 , pp. 368-376
    • Khar, A.1    Ali, A.M.2    Pardhasaradhi, B.V.3    Varalakshmi, C.H.4    Anjum, R.5    Kumari, A.L.6
  • 9
    • 33746197963 scopus 로고    scopus 로고
    • Multiple molecular targets in cancer chemoprevention by curcumin
    • Thangapazham R.L., Sharma A., and Maheshwari R.K. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS J 8 (2006) E443-E449
    • (2006) AAPS J , vol.8
    • Thangapazham, R.L.1    Sharma, A.2    Maheshwari, R.K.3
  • 10
    • 0034113598 scopus 로고    scopus 로고
    • Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile
    • Churchill M., Chadburn A., Bilinski R.T., and Bertagnolli M.M. Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile. J Surg Res 89 (2000) 169-175
    • (2000) J Surg Res , vol.89 , pp. 169-175
    • Churchill, M.1    Chadburn, A.2    Bilinski, R.T.3    Bertagnolli, M.M.4
  • 11
    • 33745202364 scopus 로고    scopus 로고
    • Dosage effects of curcumin on cell death types in a human osteoblast cell line
    • Chan W.H., Wu H.Y., and Chang W.H. Dosage effects of curcumin on cell death types in a human osteoblast cell line. Food Chem Toxicol 44 (2006) 1362-1371
    • (2006) Food Chem Toxicol , vol.44 , pp. 1362-1371
    • Chan, W.H.1    Wu, H.Y.2    Chang, W.H.3
  • 12
    • 84934443974 scopus 로고    scopus 로고
    • Curcumin as chemosensitizer
    • Limtrakul P. Curcumin as chemosensitizer. Adv Exp Med Biol 595 (2007) 269-300
    • (2007) Adv Exp Med Biol , vol.595 , pp. 269-300
    • Limtrakul, P.1
  • 13
    • 0033064548 scopus 로고    scopus 로고
    • Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells
    • Khar A., Ali A.M., Pardhasaradhi B.V., Begum Z., and Anjum R. Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells. FEBS Lett 445 (1999) 165-168
    • (1999) FEBS Lett , vol.445 , pp. 165-168
    • Khar, A.1    Ali, A.M.2    Pardhasaradhi, B.V.3    Begum, Z.4    Anjum, R.5
  • 14
    • 0034644797 scopus 로고    scopus 로고
    • Differential modulation of nitric oxide production by curcumin in host macrophages and NK cells
    • Bhaumik S., Jyothi M.D., and Khar A. Differential modulation of nitric oxide production by curcumin in host macrophages and NK cells. FEBS Lett 483 (2000) 78-82
    • (2000) FEBS Lett , vol.483 , pp. 78-82
    • Bhaumik, S.1    Jyothi, M.D.2    Khar, A.3
  • 15
    • 4644364745 scopus 로고    scopus 로고
    • Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2
    • Syng-Ai C., Kumari A.L., and Khar A. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol Cancer Ther (2004) 1101-1108
    • (2004) Mol Cancer Ther , pp. 1101-1108
    • Syng-Ai, C.1    Kumari, A.L.2    Khar, A.3
  • 16
    • 0037097660 scopus 로고    scopus 로고
    • Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes
    • Natarajan C., and Bright J.J. Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J Immunol 168 (2002) 6506-6513
    • (2002) J Immunol , vol.168 , pp. 6506-6513
    • Natarajan, C.1    Bright, J.J.2
  • 17
    • 33748748708 scopus 로고    scopus 로고
    • Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients
    • Zhang L., Fiala M., Cashman J., Sayre J., Espinosa A., Mahanian M., et al. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients. J Alzheimer's Dis 10 (2006) 1-7
    • (2006) J Alzheimer's Dis , vol.10 , pp. 1-7
    • Zhang, L.1    Fiala, M.2    Cashman, J.3    Sayre, J.4    Espinosa, A.5    Mahanian, M.6
  • 18
    • 34547101953 scopus 로고    scopus 로고
    • Pretreatment of curcumin attenuates coagulopathy and renal injury in LPS-induced endotoxemia
    • Chen H.W., Kuo H.T., Chai C.Y., Ou J.L., and Yang R.C. Pretreatment of curcumin attenuates coagulopathy and renal injury in LPS-induced endotoxemia. J Endotoxin Res 13 (2007) 15-23
    • (2007) J Endotoxin Res , vol.13 , pp. 15-23
    • Chen, H.W.1    Kuo, H.T.2    Chai, C.Y.3    Ou, J.L.4    Yang, R.C.5
  • 19
    • 34848854771 scopus 로고    scopus 로고
    • MD-2 as the target of curcumin in the inhibition of response to LPS
    • Gradisar H., Keber M.M., Pristovsek P., and Jerala R. MD-2 as the target of curcumin in the inhibition of response to LPS. J Leukoc Biol 82 (2007) 968-974
    • (2007) J Leukoc Biol , vol.82 , pp. 968-974
    • Gradisar, H.1    Keber, M.M.2    Pristovsek, P.3    Jerala, R.4
  • 20
    • 33744526702 scopus 로고    scopus 로고
    • Inhibition of homodimerization of Toll-like receptor 4 by curcumin
    • Youn H.S., Saitoh S.I., Miyake K., and Hwang D.H. Inhibition of homodimerization of Toll-like receptor 4 by curcumin. Biochem Pharmacol 72 (2006) 62-69
    • (2006) Biochem Pharmacol , vol.72 , pp. 62-69
    • Youn, H.S.1    Saitoh, S.I.2    Miyake, K.3    Hwang, D.H.4
  • 21
    • 33947532054 scopus 로고    scopus 로고
    • Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets
    • Cho J.W., Lee K.S., and Kim C.W. Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med 19 (2007) 469-474
    • (2007) Int J Mol Med , vol.19 , pp. 469-474
    • Cho, J.W.1    Lee, K.S.2    Kim, C.W.3
  • 22
    • 33646002026 scopus 로고    scopus 로고
    • Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis
    • Funk J.L., Oyarzo J.N., Frye J.B., Chen G., Lantz R.C., Jolad S.D., et al. Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. J Nat Products 69 (2006) 351-355
    • (2006) J Nat Products , vol.69 , pp. 351-355
    • Funk, J.L.1    Oyarzo, J.N.2    Frye, J.B.3    Chen, G.4    Lantz, R.C.5    Jolad, S.D.6
  • 23
    • 35148838593 scopus 로고    scopus 로고
    • Curcumin induces apoptosis and inhibits prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis
    • Park C., Moon D.O., Choi I.W., Choi B.T., Nam T.J., Rhu C.H., et al. Curcumin induces apoptosis and inhibits prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis. Int J Mol Med 20 (2007) 365-372
    • (2007) Int J Mol Med , vol.20 , pp. 365-372
    • Park, C.1    Moon, D.O.2    Choi, I.W.3    Choi, B.T.4    Nam, T.J.5    Rhu, C.H.6
  • 25
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • Pan M.H., Huang T.M., and Lin J.K. Biotransformation of curcumin through reduction and glucuronidation in mice. Drug metab dispos 27 (1999) 486-494
    • (1999) Drug metab dispos , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 27
    • 0022928028 scopus 로고
    • Microassays for superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using an enzyme immunoassay microplate reader
    • Pick E. Microassays for superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using an enzyme immunoassay microplate reader. Methods Enzymol 132 (1986) 407-421
    • (1986) Methods Enzymol , vol.132 , pp. 407-421
    • Pick, E.1
  • 28
    • 0028928877 scopus 로고
    • Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages
    • Brouet I., and Ohshima H. Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 (1995) 533-540
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 533-540
    • Brouet, I.1    Ohshima, H.2
  • 29
    • 20444413788 scopus 로고    scopus 로고
    • Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate
    • Okazaki Y., Iqbal M., and Okada S. Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate. Biochim Biophys Acta 1740 (2005) 357-366
    • (2005) Biochim Biophys Acta , vol.1740 , pp. 357-366
    • Okazaki, Y.1    Iqbal, M.2    Okada, S.3
  • 30
    • 33846889718 scopus 로고    scopus 로고
    • "Spicing up" of the immune system by curcumin
    • Jagetia G.C., and Aggarwal B.B. "Spicing up" of the immune system by curcumin. J Clin Immunol 27 (2007) 19-35
    • (2007) J Clin Immunol , vol.27 , pp. 19-35
    • Jagetia, G.C.1    Aggarwal, B.B.2
  • 31
    • 2942624044 scopus 로고    scopus 로고
    • Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro
    • Gao X., Kuo J., Jiang H., Deeb D., Liu Y., Divine G., et al. Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro. Biochem Pharmacol 68 (2004) 51-61
    • (2004) Biochem Pharmacol , vol.68 , pp. 51-61
    • Gao, X.1    Kuo, J.2    Jiang, H.3    Deeb, D.4    Liu, Y.5    Divine, G.6
  • 33
    • 34447530391 scopus 로고    scopus 로고
    • Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction
    • Bhattacharyya S., Mandal D., Saha B., Sen G.S., Das T., and Sa G. Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction. J Biol Chem 282 (2007) 15954-15964
    • (2007) J Biol Chem , vol.282 , pp. 15954-15964
    • Bhattacharyya, S.1    Mandal, D.2    Saha, B.3    Sen, G.S.4    Das, T.5    Sa, G.6
  • 34
    • 0032124324 scopus 로고    scopus 로고
    • Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation
    • Ranjan D., Johnston T.D., Wu G., Elliott L., Bondada S., and Nagabhushan M. Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation. J Surg Res 7 (1998) 174-178
    • (1998) J Surg Res , vol.7 , pp. 174-178
    • Ranjan, D.1    Johnston, T.D.2    Wu, G.3    Elliott, L.4    Bondada, S.5    Nagabhushan, M.6
  • 35
    • 0038629458 scopus 로고    scopus 로고
    • Effects of curcumin on cyclosporine-induced cholestasis and hypercholesterolemia and on cyclosporine metabolism in the rat
    • Deters M., Klabunde T., Meyer H., Resch K., and Kaever V. Effects of curcumin on cyclosporine-induced cholestasis and hypercholesterolemia and on cyclosporine metabolism in the rat. Planta Med 69 (2003) 337-343
    • (2003) Planta Med , vol.69 , pp. 337-343
    • Deters, M.1    Klabunde, T.2    Meyer, H.3    Resch, K.4    Kaever, V.5
  • 36
    • 0027639580 scopus 로고
    • Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, and alters populations of the lymphocytes in mice
    • Yasni S., Yoshiie K., Oda H., Sugano M., and Imaizumi K. Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, and alters populations of the lymphocytes in mice. J Nutr Sci Vitaminol 39 (1993) 345-354
    • (1993) J Nutr Sci Vitaminol , vol.39 , pp. 345-354
    • Yasni, S.1    Yoshiie, K.2    Oda, H.3    Sugano, M.4    Imaizumi, K.5
  • 37
    • 35348853689 scopus 로고    scopus 로고
    • Pharmacological doses of dietary curcumin increase colon epithelial cell proliferation in vivo in rats
    • Kim S.J., and Hellerstein M.K. Pharmacological doses of dietary curcumin increase colon epithelial cell proliferation in vivo in rats. Phytother Res. 21 (2007) 995-998
    • (2007) Phytother Res. , vol.21 , pp. 995-998
    • Kim, S.J.1    Hellerstein, M.K.2
  • 39
    • 33845937786 scopus 로고    scopus 로고
    • Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats
    • Zhang W., Tan T.M., and Lim L.Y. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. Drug Metab Dispo.: The biological fate of chemicals 35 (2007) 110-115
    • (2007) Drug Metab Dispo.: The biological fate of chemicals , vol.35 , pp. 110-115
    • Zhang, W.1    Tan, T.M.2    Lim, L.Y.3
  • 40
    • 5144221545 scopus 로고    scopus 로고
    • Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder
    • Chearwae W., Anuchapreeda S., Nandigama K., Ambudkar S.V., and Limtrakul P. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. Biochem Pharmacol 68 (2004) 2043-2052
    • (2004) Biochem Pharmacol , vol.68 , pp. 2043-2052
    • Chearwae, W.1    Anuchapreeda, S.2    Nandigama, K.3    Ambudkar, S.V.4    Limtrakul, P.5
  • 41
    • 0037103569 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells
    • Anuchapreeda S., Leechanachai P., Smith M.M., Ambudkar S.V., and Limtrakul P.N. Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem Pharmacol 64 (2002) 573-582
    • (2002) Biochem Pharmacol , vol.64 , pp. 573-582
    • Anuchapreeda, S.1    Leechanachai, P.2    Smith, M.M.3    Ambudkar, S.V.4    Limtrakul, P.N.5
  • 42
    • 0034782946 scopus 로고    scopus 로고
    • Redox signaling in macrophages
    • Forman H.J., and Torres M. Redox signaling in macrophages. Mol Aspects Med 22 (2001) 189-216
    • (2001) Mol Aspects Med , vol.22 , pp. 189-216
    • Forman, H.J.1    Torres, M.2
  • 43
    • 0141529729 scopus 로고    scopus 로고
    • Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells
    • Chan W.H., Wu C.C., and Yu J.S. Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells. J Cell Biochem 90 (2003) 327-338
    • (2003) J Cell Biochem , vol.90 , pp. 327-338
    • Chan, W.H.1    Wu, C.C.2    Yu, J.S.3
  • 44
    • 0032815637 scopus 로고    scopus 로고
    • Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates
    • Bhaumik S., Anjum R., Rangaraj N., Pardhasaradhi B.V., and Khar A. Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates. FEBS Lett 456 (1999) 311-314
    • (1999) FEBS Lett , vol.456 , pp. 311-314
    • Bhaumik, S.1    Anjum, R.2    Rangaraj, N.3    Pardhasaradhi, B.V.4    Khar, A.5
  • 45
    • 15744370742 scopus 로고    scopus 로고
    • Curcumin-induced histone hypoacetylation: the role of reactive oxygen species
    • Kang J., Chen J., Shi Y., Jia J., and Zhang Y. Curcumin-induced histone hypoacetylation: the role of reactive oxygen species. Biochem pharmacol. 69 (2005) 1205-1213
    • (2005) Biochem pharmacol. , vol.69 , pp. 1205-1213
    • Kang, J.1    Chen, J.2    Shi, Y.3    Jia, J.4    Zhang, Y.5
  • 46
    • 12344306413 scopus 로고    scopus 로고
    • Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide
    • Chander V., and Chopra K. Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide. Toxicology 207 (2005) 463-474
    • (2005) Toxicology , vol.207 , pp. 463-474
    • Chander, V.1    Chopra, K.2
  • 47
    • 16244405915 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin protects against cyclosporine-induced nephrotoxicity through nitric oxide dependent mechanism
    • Chander V., Tirkey N., and Chopra K. Resveratrol, a polyphenolic phytoalexin protects against cyclosporine-induced nephrotoxicity through nitric oxide dependent mechanism. Toxicology 210 (2005) 55-64
    • (2005) Toxicology , vol.210 , pp. 55-64
    • Chander, V.1    Tirkey, N.2    Chopra, K.3
  • 48
    • 1442333588 scopus 로고    scopus 로고
    • Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression
    • Kim S.H., Kim J., and Sharma R.P. Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression. Pharmacol Res 49 (2004) 433-439
    • (2004) Pharmacol Res , vol.49 , pp. 433-439
    • Kim, S.H.1    Kim, J.2    Sharma, R.P.3
  • 49
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. Nitric oxide and the immune response. Nature Immunol 2 (2001) 907-916
    • (2001) Nature Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 51
    • 0037014331 scopus 로고    scopus 로고
    • Differential modulation of host macrophage function by AK-5 tumor is dependent on the site of tumor transplantation
    • Mitra R., Bhaumik S., and Khar A. Differential modulation of host macrophage function by AK-5 tumor is dependent on the site of tumor transplantation. Immunol Lett 82 (2002) 183-190
    • (2002) Immunol Lett , vol.82 , pp. 183-190
    • Mitra, R.1    Bhaumik, S.2    Khar, A.3
  • 52
    • 0035872248 scopus 로고    scopus 로고
    • Activated macrophages migrate to the subcutaneous tumor site via the peritoneum: a novel route of cell trafficking
    • Bhaumik S., Mitra R., Varalakshmi C., and Khar A. Activated macrophages migrate to the subcutaneous tumor site via the peritoneum: a novel route of cell trafficking. Exp Cell Res 266 (2001) 44-52
    • (2001) Exp Cell Res , vol.266 , pp. 44-52
    • Bhaumik, S.1    Mitra, R.2    Varalakshmi, C.3    Khar, A.4
  • 53
    • 0036828821 scopus 로고    scopus 로고
    • Role of reactive nitrogen intermediates and protein nitration during immune response against a rat histiocytoma
    • Mitra R., and Khar A. Role of reactive nitrogen intermediates and protein nitration during immune response against a rat histiocytoma. Immunol Lett 84 (2002) 145-151
    • (2002) Immunol Lett , vol.84 , pp. 145-151
    • Mitra, R.1    Khar, A.2
  • 54
    • 0344766073 scopus 로고    scopus 로고
    • Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages
    • Hortelano S., Lopez-Collazo E., and Bosca L. Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. Br J Pharmacol 126 (1999) 1139-1146
    • (1999) Br J Pharmacol , vol.126 , pp. 1139-1146
    • Hortelano, S.1    Lopez-Collazo, E.2    Bosca, L.3
  • 55
    • 0031562674 scopus 로고    scopus 로고
    • Natural killer cell as the effector which mediates in vivo apoptosis in AK-5 tumor cells
    • Khar A., Pardhasaradhi B.V., Varalakshmi C., Ali A.M., and Kumari A.L. Natural killer cell as the effector which mediates in vivo apoptosis in AK-5 tumor cells. Cell Immunol 177 (1997) 86-92
    • (1997) Cell Immunol , vol.177 , pp. 86-92
    • Khar, A.1    Pardhasaradhi, B.V.2    Varalakshmi, C.3    Ali, A.M.4    Kumari, A.L.5
  • 56
    • 0037008854 scopus 로고    scopus 로고
    • Regulation of NK cell function in vivo by the dose of tumour transplanted in the peritoneum
    • Das S., and Khar A. Regulation of NK cell function in vivo by the dose of tumour transplanted in the peritoneum. Immunol Lett 83 (2002) 133-142
    • (2002) Immunol Lett , vol.83 , pp. 133-142
    • Das, S.1    Khar, A.2
  • 57
    • 34250158095 scopus 로고    scopus 로고
    • Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity
    • Zhang H.G., Kim H., Liu C., Yu S., Wang J., Grizzle W.E., et al. Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity. Biochim Biophys Acta 1773 (2007) 1116-1123
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1116-1123
    • Zhang, H.G.1    Kim, H.2    Liu, C.3    Yu, S.4    Wang, J.5    Grizzle, W.E.6
  • 58
    • 0032883350 scopus 로고    scopus 로고
    • Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages
    • Kang B.Y., Song Y.J., Kim K.M., Choe Y.K., Hwang S.Y., and Kim T.S. Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages. Br J Pharmcol 128 (1999) 380-384
    • (1999) Br J Pharmcol , vol.128 , pp. 380-384
    • Kang, B.Y.1    Song, Y.J.2    Kim, K.M.3    Choe, Y.K.4    Hwang, S.Y.5    Kim, T.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.