Estrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice

Clinical Immunology

Volumn 158, Issue 2, 2015, Pages 153-166

  Yoachim, Shayla D ^a   Nuxoll, Jenny S ^a   Bynoté, Kimberly K ^a   Gould, Karen A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Estrogen receptor alpha; Immune cell activation; Immunologic tolerance; Lupus; Sex bias

Indexed keywords

ANTINUCLEAR ANTIBODY; ESTROGEN RECEPTOR ALPHA; EPITOPE; ESTROGEN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; B LYMPHOCYTE ACTIVATION; CONGENIC STRAIN; CONTROLLED STUDY; ESTROGEN ACTIVITY; EXON; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOSITY; IMMUNOCOMPETENT CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OVARIECTOMY; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING; WILD TYPE; ANIMAL; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; EPITOPES; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICE; MICE, KNOCKOUT; SEX FACTORS; SIGNAL TRANSDUCTION;

EID: 84928622186     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.03.026     Document Type: Article

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