A dexamethasone prodrug reduces the renal macrophage response and provides enhanced resolution of established murine lupus nephritis

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Yuan, Fang ^a   Tabor, Dana E ^a   Nelson, Richard K ^a   Yuan, Hongjiang ^a   Zhang, Yijia ^a   Nuxoll, Jenny ^a   Bynoté, Kimberly K ^a   Lele, Subodh M ^b   Wang, Dong ^a   Gould, Karen A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; DEXAMETHASONE PRODRUG; DEXAMETHASONE SODIUM PHOSPHATE; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; UNCLASSIFIED DRUG; PRODRUG;

ADRENAL CORTEX ATROPHY; ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE DENSITY; BONE MASS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG SAFETY; FEMALE; HYPERTENSION; IMMUNE COMPLEX DEPOSITION; INTERSTITIAL NEPHRITIS; LEUKOCYTE COUNT; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; SPLENOMEGALY; SURVIVAL RATE; VASCULITIS; ANIMAL; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; KIDNEY; LUPUS NEPHRITIS; METABOLISM; SURVIVAL; TIME;

ALBUMINURIA; ANIMALS; DEXAMETHASONE; DISEASE MODELS, ANIMAL; HYPERTENSION; KIDNEY; LUPUS NEPHRITIS; MACROPHAGES; MICE; NEPHRITIS, INTERSTITIAL; PRODRUGS; SPLENOMEGALY; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 84896700318     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081483     Document Type: Article

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