Interactions between nuclear receptor SHP and FOXA1 maintain oscillatory homocysteine homeostasis in mice

Gastroenterology

Volumn 148, Issue 5, 2015, Pages 1012-1023.e14

  Tsuchiya, Hiroyuki ^a   Da Costa, Kerry Ann ^b   Lee, Sangmin ^c   Renga, Barbara ^d   Jaeschke, Hartmut ^e   Yang, Zhihong ^c,f   Orena, Stephen J ^b   Goedken, Michael J ^g   Zhang, Yuxia ^e   Kong, Bo ^g   Lebofsky, Margitta ^e   Rudraiah, Swetha ^c   Smalling, Rana ^a   Guo, Grace ^g   Fiorucci, Stefano ^d   Zeisel, Steven H ^b   Wang, Li ^c,f,h  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b IL   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

^e UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^f VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^g RUTGERS UNIVERSITY   (United States)

^h YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circadian Regulation; Liver Disease Model; Metabolism; Nuclear Receptor

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALCOHOL; BETA SYNTHETASE; BETAINE; BETAINE HOMOCYSTEINE METHYLTRANSFERASE; CELL NUCLEUS RECEPTOR; CHOLIC ACID; CHOLINE; CHOLINE DEHYDROGENASE; CHOLINE DERIVATIVE; COLESTYRAMINE; CYSTATHIONINE; CYSTATHIONINE GAMMA LYASE; CYSTEINE; GLUTAMINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLYCEOPHOSPHOCHOLINE; GLYCINE; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HOMOCYSTEINE; HYDROGEN SULFIDE; NUCLEAR RECEPTOR SHP; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; PHOSPHORYLCHOLINE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG; BHMT PROTEIN, MOUSE; CELL RECEPTOR; FOXA1 PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; MESSENGER RNA; NUCLEAR RECEPTOR SUBFAMILY 0, GROUP B, MEMBER 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; FAT CONTENT; GENE EXPRESSION; GLUCOSE INTOLERANCE; HOMEOSTASIS; HYPERHOMOCYSTEINEMIA; IMMUNOBLOTTING; LIPID DIET; LIPID METABOLISM; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; METABOLOMICS; MOUSE; NONHUMAN; OSCILLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; BLOOD; CHEMICALLY INDUCED; CIRCADIAN RHYTHM; DEFICIENCY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE BLOOD LEVEL; KNOCKOUT MOUSE; LIVER; METABOLISM; TIME;

ANIMALS; BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE; BLOOD GLUCOSE; CHOLESTYRAMINE RESIN; CHOLIC ACID; CIRCADIAN RHYTHM; CYSTATHIONINE GAMMA-LYASE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE INTOLERANCE; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HOMEOSTASIS; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; LIVER; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84928615897     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.01.045     Document Type: Article

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