HIV-1 Nef and Vpu interfere with L-selectin (CD62L) cell surface expression to inhibit adhesion and signaling in infected CD4+ T lymphocytes

Journal of Virology

Volumn 89, Issue 10, 2015, Pages 5687-5700

  Vassena, Lia ^a   Giuliani, Erica ^a   Koppensteiner, Herwig ^b   Bolduan, Sebastian ^b   Schindler, Michael ^b,c   Doria, Margherita ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; L SELECTIN; NEF PROTEIN; VPU PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; VIRUS PROTEIN; VPU PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL ADHESION; CELL MEMBRANE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS IDENTIFICATION; CELL CULTURE; HOST PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; JURKAT CELL LINE; METABOLISM; PATHOGENICITY; PHYSIOLOGY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CELLS, CULTURED; DOWN-REGULATION; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; JURKAT CELLS; L-SELECTIN; LYMPHOCYTE ACTIVATION; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84928564447     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00611-15     Document Type: Article

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