The fruit extract of Berberis crataegina DC: Exerts potent antioxidant activity and protects DNA integrity

DARU, Journal of Pharmaceutical Sciences

Volumn 23, Issue 1, 2015, Pages

  Charehsaz, Mohammad ^a   Sipahi, Hande ^a   Celep, Engin ^a   Üstündaʇ, Aylin ^b   Cemiloʇlu Ülker, Özge ^b   Duydu, Yalçln ^b   Aydln, Ahmet ^a   Yesilada, Erdem ^a  

^a YEDITEPE UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

Antioxidant; Berberis crataegina DC; Folk medicine; Genotoxicity; Lipid peroxidation

Indexed keywords

ANTIOXIDANT; BERBERIS CRATAEGINA FRUIT EXTRACT; DNA; FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; PROANTHOCYANIDIN; UNCLASSIFIED DRUG; 1,1-DIPHENYL-2-PICRYLHYDRAZYL; BIPHENYL DERIVATIVE; HYDROGEN PEROXIDE; PICRIC ACID;

ANTIOXIDANT ACTIVITY; ARTICLE; BERBERIS; BERBERIS CRATAEGINA; CERVICAL CANCER CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; FEMALE; FRUIT; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; ADULT; CHEMISTRY; COMET ASSAY; DRUG EFFECTS; HELA CELL LINE; LYMPHOCYTE; TRADITIONAL MEDICINE; TURKEY;

ADULT; ANTIOXIDANTS; BERBERIS; BIPHENYL COMPOUNDS; COMET ASSAY; DNA DAMAGE; FEMALE; FLAVONOIDS; FRUIT; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; LYMPHOCYTES; MEDICINE, TRADITIONAL; PHENOLS; PICRATES; PLANT EXTRACTS; TURKEY;

EID: 84928548871     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/s40199-015-0108-7     Document Type: Article

References (23)

1. Zovko-Koncic M, Kremer D, Karlovic K, Kosalec I. Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. Food Chem Toxicol. 2010;48:2176-80.
2. Rouhani S, Salehi N, Kamalinejad M, Zayeri F. Efficacy of Berberis vulgaris aqueous extract on viability of Echinococcus granulosus protoscolices. J Invest Surg. 2013;26:347-51.
3. Kim M, Cho KO, Shin MS, Lee JM, Cho HS, Kim CJ, et al. Berberine prevents nigrostriatal dopaminergic neuronal loss and suppresses hippocampal apoptosis in mice with Parkinson's disease. Int J Mol Med. 2014;33:870-8.
4. Sezik E, Yesilada E, Tabata M, Honda G, Takaishi Y, Fujita T, et al. Traditional medicine in Turkey VIII. Folk medicine in east anatolia; Erzurum, Erzíncan, Aʇri, Kars, Iʇdir provinces. Econ Bot. 1997;51:195-211.
5. Yesilada E, Kupeli E. Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J Ethnopharmacol. 2002;79:237-48.
6. Ardestani SB, Sahari MA, Barzegar M, Abbasi S. Some Physicochemical Properties of Iranian Native Barberry Fruits (abi and poloei): Berberis integerrima and Berberis vulgaris. J Food Pharm Sci. 2013;1:60-7.
7. Ivanovska N, Philipov S. Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. Int J Immunopharmacol. 1996;18:553-61.
8. Kupeli E, Kosar M, Yesilada E, Baser KHC. A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sci. 2002;72:645-57.
9. Yesilada E. Biodiversity in Turkish Folk Medicine. In: Sener B, editor. Biodiversity: Biomolecular aspects of biodiversity and innovative utilization. London: Kluwer Academic/Plenum Publishers; 2002. p. 119-35.
10. Kohen R, Nyska A. Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol. 2002;30:620-50.
11. Apel K, Hirt H. Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol. 2004;55:373-99.
12. Sun L, Zhang J, Lu X, Zhang L, Zhang Y. Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves. Food Chem Toxicol. 2011;49:2689-96.
13. Celep E, Aydin A, Kirmizibekmez H, Yesilada E. Appraisal of in vitro and in vivo antioxidant activity potential of cornelian cherry leaves. Food Chem Toxicol. 2013;62:448-55.
14. Hanachi P, Kua S, Asmah R, Motalleb G, Fauziah O. Cytotoxic effect of Berberis vulgaris fruit extract on the proliferation of human liver cancer cell line (HepG2) and its antioxidant properties. Int J Cancer Res. 2006;2:1-9.
15. Celep E, Aydin A, Yesilada E. A comparative study on the in vitro antioxidant potentials of three edible fruits: cornelian cherry, Japanese persimmon and cherry laurel. Food Chem Toxicol. 2012;50:3329-35.
16. Üstündaʇ A, Simsek K, Ay H, Dundar K, Suzen S, Aydin A, et al. DNA integrity in patients undergoing hyperbaric oxygen (HBO) therapy. Toxicol In Vitro. 2012;26:1209-15.
17. Duydu Y, Basaran N, Üstündaʇ A, Aydin S, Undeger U, Ataman OY, et al. Assessment of DNA integrity (COMET assay) in sperm cells of boron-exposed workers. Arch Toxicol. 2012;86:27-35.
18. National Institute of Health. Guidance document on using in vitro data to estimate in vivo starting doses for acute toxicity. NIH Publication 2001 No. 01-4500. 2001.
19. Gundogdu M. Determination of antioxidant capacities and biochemical compounds of Berberis vulgaris L. fruits. Adv Environ Biol. 2013;7:344-8.
20. Kukula-Koch W, Aligiannis N, Halabalaki M, Skaltsounis AL, Glowniak K, Kalpoutzakis E. Influence of extraction procedures on phenolic content and antioxidant activity of Cretan barberry herb. Food Chem. 2013;138:406-13.
21. Ruiz A, Hermosin-Gutierrez I, Mardones C, Vergara C, Herlitz E, Vega M, et al. Polyphenols and antioxidant activity of calafate (Berberis microphylla) fruits and other native berries from Southern Chile. J Agric Food Chem. 2010;2010(58):6081-9.
22. Silva JP, Gomes AC, Coutinho OP. Oxidative DNA damage protection and repair by polyphenolic compounds in PC12 cells. Eur J Pharmacol. 2008;601:50-60.
23. Akbulut, Callslr S, Marakoglu T, Coklar H. Some Physicomechanical and nutritional properties of barberry (Berberis vulgaris L.) fruits. J Food Process Eng. 2009;32:497-511.