-
1
-
-
79751531393
-
Heart disease and stroke statistics-2011 update: A report from the American Heart Association
-
Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2011 update: A report from the American Heart Association. Circulation 2011; 123:e18-e209.
-
(2011)
Circulation
, vol.123
, pp. e18-e209
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
-
2
-
-
84883569291
-
Epidemiology of heart failure
-
Roger VL. Epidemiology of heart failure. Circ Res 2013; 113:646-659.
-
(2013)
Circ Res
, vol.113
, pp. 646-659
-
-
Roger, V.L.1
-
3
-
-
84872847888
-
Phosphodiesterase type 3a regulates basal myocardial contractility through interactingwith sarcoplasmic reticulumcalcium ATPase type 2a signaling complexes inmouse heart
-
Beca S, Ahmad F, Shen W, et al. Phosphodiesterase type 3a regulates basal myocardial contractility through interactingwith sarcoplasmic reticulumcalcium ATPase type 2a signaling complexes inmouse heart. Circ Res2013; 112:289-297.
-
(2013)
Circ Res
, vol.112
, pp. 289-297
-
-
Beca, S.1
Ahmad, F.2
Shen, W.3
-
5
-
-
84919372306
-
Cyclic nucleotide phosphodiesterases important signaling modulators and therapeutic targets
-
Ahmad F, Murata T, Shimizu K, et al. Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets. Oral Dis 2015; 21:e25-e50.
-
(2015)
Oral Dis
, vol.21
, pp. e25-e50
-
-
Ahmad, F.1
Murata, T.2
Shimizu, K.3
-
6
-
-
79955664087
-
Mammalian cyclic nucleotide phosphodiesterases: Molecular mechanisms and physiological functions
-
Francis SH, Blount MA, Corbin JD. Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions. Physiol Rev 2011; 91:651-690.
-
(2011)
Physiol Rev
, vol.91
, pp. 651-690
-
-
Francis, S.H.1
Blount, M.A.2
Corbin, J.D.3
-
7
-
-
0027283557
-
Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase
-
Taira M, Hockman SC, Calvo JC, et al. Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase. J Biol Chem 1993; 268:18573-18579.
-
(1993)
J Biol Chem
, vol.268
, pp. 18573-18579
-
-
Taira, M.1
Hockman, S.C.2
Calvo, J.C.3
-
8
-
-
0026552359
-
Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase
-
Meacci E, Taira M, Moos M Jr, et al. Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase. Proc Natl Acad Sci U S A 1992; 89:3721-3725.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 3721-3725
-
-
Meacci, E.1
Taira, M.2
Moos, M.3
-
9
-
-
0031722958
-
Phospholamban: Protein structure, mechanism of action, and role in cardiac function
-
Simmerman HK, Jones LR. Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol Rev 1998; 78:921-947.
-
(1998)
Physiol Rev
, vol.78
, pp. 921-947
-
-
Simmerman, H.K.1
Jones, L.R.2
-
10
-
-
0024807866
-
Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase
-
Takasago T, Imagawa T, Shigekawa M. Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase. J Biochem (Tokyo) 1989; 106:872-877.
-
(1989)
J Biochem (Tokyo)
, vol.106
, pp. 872-877
-
-
Takasago, T.1
Imagawa, T.2
Shigekawa, M.3
-
11
-
-
0019982539
-
Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts
-
Bristow MR, Ginsburg R, Minobe W, et al. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med 1982; 307:205-211.
-
(1982)
N Engl J Med
, vol.307
, pp. 205-211
-
-
Bristow, M.R.1
Ginsburg, R.2
Minobe, W.3
-
12
-
-
0022980843
-
Beta 1-and beta 2-adrenergicreceptor subpopulations in nonfailing and failing human ventricularmyocardium: Coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure
-
Bristow MR, Ginsburg R, Umans V, et al. Beta 1-and beta 2-adrenergicreceptor subpopulations in nonfailing and failing human ventricularmyocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res 1986; 59:297-309.
-
(1986)
Circ Res
, vol.59
, pp. 297-309
-
-
Bristow, M.R.1
Ginsburg, R.2
Umans, V.3
-
13
-
-
0028179295
-
Expression of beta-arrestins and betaadrenergic receptor kinases in the failing human heart
-
Ungerer M, Parruti G, Bohm M, et al. Expression of beta-arrestins and betaadrenergic receptor kinases in the failing human heart. Circ Res 1994; 74:206-213.
-
(1994)
Circ Res
, vol.74
, pp. 206-213
-
-
Ungerer, M.1
Parruti, G.2
Bohm, M.3
-
14
-
-
0027497584
-
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
-
Ungerer M, Bohm M, Elce JS, et al. Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 1993; 87:454-463.
-
(1993)
Circulation
, vol.87
, pp. 454-463
-
-
Ungerer, M.1
Bohm, M.2
Elce, J.S.3
-
15
-
-
0024294725
-
Increase in myocardial G-proteins in heart failure
-
Neumann J, Schmitz W, Scholz H, et al. Increase in myocardial G-proteins in heart failure. Lancet 1988; 2:936-937.
-
(1988)
Lancet
, vol.2
, pp. 936-937
-
-
Neumann, J.1
Schmitz, W.2
Scholz, H.3
-
16
-
-
0023733494
-
Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart
-
Feldman AM, Cates AE, Veazey WB, et al. Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart. J Clin Invest 1988; 82:189-197.
-
(1988)
J Clin Invest
, vol.82
, pp. 189-197
-
-
Feldman, A.M.1
Cates, A.E.2
Veazey, W.B.3
-
17
-
-
0023130366
-
Deficient production of cyclic AMP: Pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure
-
Feldman MD, Copelas L, Gwathmey JK, et al. Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure. Circulation 1987; 75:331-339.
-
(1987)
Circulation
, vol.75
, pp. 331-339
-
-
Feldman, M.D.1
Copelas, L.2
Gwathmey, J.K.3
-
18
-
-
0024371642
-
Basal and isoprenalinestimulated cAMP content in failing versus nonfailing human cardiac preparations
-
Danielsen W, v der Leyen H, Meyer W, et al. Basal and isoprenalinestimulated cAMP content in failing versus nonfailing human cardiac preparations. J Cardiovasc Pharmacol 1989; 14:171-173.
-
(1989)
J Cardiovasc Pharmacol
, vol.14
, pp. 171-173
-
-
Danielsen, W.1
Der Leyen H, V.2
Meyer, W.3
-
19
-
-
85047679474
-
CAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in nonfailing and failing myocardium
-
Bohm M, Reiger B, Schwinger RH, Erdmann E. cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in nonfailing and failing myocardium. Cardiovasc Res 1994; 28:1713-1719.
-
(1994)
Cardiovasc Res
, vol.28
, pp. 1713-1719
-
-
Bohm, M.1
Reiger, B.2
Schwinger, R.H.3
Erdmann, E.4
-
20
-
-
0026542534
-
Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure
-
Beuckelmann DJ, Nabauer M, Erdmann E. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 1992; 85:1046-1055.
-
(1992)
Circulation
, vol.85
, pp. 1046-1055
-
-
Beuckelmann, D.J.1
Nabauer, M.2
Erdmann, E.3
-
21
-
-
0020605971
-
Evaluation of a new bipyridine inotropic agent-milrinone-in patients with severe congestive heart failure
-
Baim DS, McDowell AV, Cherniles J, et al. Evaluation of a new bipyridine inotropic agent-milrinone-in patients with severe congestive heart failure. N Engl J Med 1983; 309:748-756.
-
(1983)
N Engl J Med
, vol.309
, pp. 748-756
-
-
Baim, D.S.1
McDowell, A.V.2
Cherniles, J.3
-
22
-
-
0018246273
-
Hemodynamic assessment of amrinone. A new inotropic agent
-
Benotti JR, Grossman W, Braunwald E, et al. Hemodynamic assessment of amrinone. A new inotropic agent. N Engl J Med 1978; 299:1373-1377.
-
(1978)
N Engl J Med
, vol.299
, pp. 1373-1377
-
-
Benotti, J.R.1
Grossman, W.2
Braunwald, E.3
-
23
-
-
0022001187
-
Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside
-
Jaski BE, Fifer MA, Wright RF, et al. Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside. J Clin Invest 1985; 75:643-649.
-
(1985)
J Clin Invest
, vol.75
, pp. 643-649
-
-
Jaski, B.E.1
Fifer, M.A.2
Wright, R.F.3
-
24
-
-
0020533858
-
Long-term therapy with a new cardiotonic agent, WIN 47203: Drug-dependent improvement in cardiac performance and progression of the underlying disease
-
Sinoway LS, Maskin CS, Chadwick B, et al. Long-term therapy with a new cardiotonic agent, WIN 47203: drug-dependent improvement in cardiac performance and progression of the underlying disease. J Am Coll Cardiol 1983; 2:327-331.
-
(1983)
J Am Coll Cardiol
, vol.2
, pp. 327-331
-
-
Sinoway, L.S.1
Maskin, C.S.2
Chadwick, B.3
-
25
-
-
0020567448
-
Sustained hemodynamic and clinical effects of a new cardiotonic agent, WIN 47203, in patients with severe congestive heart failure
-
Maskin CS, Sinoway L, Chadwick B, et al. Sustained hemodynamic and clinical effects of a new cardiotonic agent, WIN 47203, in patients with severe congestive heart failure. Circulation 1983; 67:1065-1070.
-
(1983)
Circulation
, vol.67
, pp. 1065-1070
-
-
Maskin, C.S.1
Sinoway, L.2
Chadwick, B.3
-
26
-
-
0025755546
-
Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: Results of a multicenter study in the United States
-
Anderson JL. Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: results of a multicenter study in the United States. Am Heart J 1991; 121:1956-1964.
-
(1991)
Am Heart J
, vol.121
, pp. 1956-1964
-
-
Anderson, J.L.1
-
27
-
-
0021711224
-
Improvement in indexes of diastolic performance in patients with congestive heart failure treated with milrinone
-
Monrad ES, McKay RG, Baim DS, et al. Improvement in indexes of diastolic performance in patients with congestive heart failure treated with milrinone. Circulation 1984; 70:1030-1037.
-
(1984)
Circulation
, vol.70
, pp. 1030-1037
-
-
Monrad, E.S.1
McKay, R.G.2
Baim, D.S.3
-
28
-
-
65549140547
-
Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure
-
Drakos SG, Kanakakis JV, Nanas S, et al. Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure. J Cardiovasc Pharmacol 2009; 53:157-161.
-
(2009)
J Cardiovasc Pharmacol
, vol.53
, pp. 157-161
-
-
Drakos, S.G.1
Kanakakis, J.V.2
Nanas, S.3
-
29
-
-
1842732159
-
Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling
-
del Monte F, Lebeche D, Guerrero JL, et al. Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proc Natl Acad Sci U S A 2004; 101:5622-5627.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 5622-5627
-
-
Del Monte, F.1
Lebeche, D.2
Guerrero, J.L.3
-
30
-
-
80052342152
-
Serca2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure
-
Lyon AR, Bannister ML, Collins T, et al. Serca2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure. Circ Arrhythm Electrophysiol 2011; 4:362-372.
-
(2011)
Circ Arrhythm Electrophysiol
, vol.4
, pp. 362-372
-
-
Lyon, A.R.1
Bannister, M.L.2
Collins, T.3
-
31
-
-
26844504704
-
A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis
-
Ding B, Abe J, Wei H, et al. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc Natl Acad Sci U S A 2005; 102:14771-14776.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14771-14776
-
-
Ding, B.1
Abe, J.2
Wei, H.3
-
32
-
-
21044453725
-
Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: Implication in heart failure
-
Ding B, Abe J, Wei H, et al. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. Circulation 2005; 111:2469-2476.
-
(2005)
Circulation
, vol.111
, pp. 2469-2476
-
-
Ding, B.1
Abe, J.2
Wei, H.3
-
33
-
-
84883701893
-
Cyclic nucleotide phosphodiesterase 3a1 protects the heart against ischemia-reperfusion injury
-
Oikawa M, Wu M, Lim S, et al. Cyclic nucleotide phosphodiesterase 3a1 protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol 2013; 64:11-19.
-
(2013)
J Mol Cell Cardiol
, vol.64
, pp. 11-19
-
-
Oikawa, M.1
Wu, M.2
Lim, S.3
-
34
-
-
59449098471
-
Apoptotic and nonapoptotic programmed cardiomyocyte death in ventricular remodelling
-
Dorn GW 2nd. Apoptotic and nonapoptotic programmed cardiomyocyte death in ventricular remodelling. Cardiovasc Res 2009; 81:465-473.
-
(2009)
Cardiovasc Res
, vol.81
, pp. 465-473
-
-
Dorn, G.W.1
-
35
-
-
84877918970
-
New therapeutic targets in cardiology: Heart failure and arrhythmia: HCN channels
-
Roubille F, Tardif JC. New therapeutic targets in cardiology: heart failure and arrhythmia: HCN channels. Circulation 2013; 127:1986-1996.
-
(2013)
Circulation
, vol.127
, pp. 1986-1996
-
-
Roubille, F.1
Tardif, J.C.2
-
36
-
-
84880939628
-
Exchange protein directly activated by cAMP (epac): A multidomain cAMP mediator in the regulation of diverse biological functions
-
Schmidt M, Dekker FJ, Maarsingh H. Exchange protein directly activated by cAMP (epac): A multidomain cAMP mediator in the regulation of diverse biological functions. Pharmacol Rev 2013; 65:670-709.
-
(2013)
Pharmacol Rev
, vol.65
, pp. 670-709
-
-
Schmidt, M.1
Dekker, F.J.2
Maarsingh, H.3
-
37
-
-
79955789030
-
Rap-linked cAMP signaling epac proteins: Compartmentation, functioning and disease implications
-
Breckler M, Berthouze M, Laurent AC, et al. Rap-linked cAMP signaling epac proteins: compartmentation, functioning and disease implications. Cell Signal 2011; 23:1257-1266.
-
(2011)
Cell Signal
, vol.23
, pp. 1257-1266
-
-
Breckler, M.1
Berthouze, M.2
Laurent, A.C.3
-
38
-
-
59449094232
-
Epac and phospholipase Cepsilon regulate ca2 release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II
-
Oestreich EA, Malik S, Goonasekera SA, et al. Epac and phospholipase Cepsilon regulate ca2 release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II. J Biol Chem 2009; 284:1514-1522.
-
(2009)
J Biol Chem
, vol.284
, pp. 1514-1522
-
-
Oestreich, E.A.1
Malik, S.2
Goonasekera, S.A.3
-
39
-
-
34247124160
-
Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2 mobilization in cardiac myocytes
-
Oestreich EA, Wang H, Malik S, et al. Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2 mobilization in cardiac myocytes. J Biol Chem 2007; 282:5488-5495.
-
(2007)
J Biol Chem
, vol.282
, pp. 5488-5495
-
-
Oestreich, E.A.1
Wang, H.2
Malik, S.3
-
40
-
-
34548322692
-
The cAMP binding protein epac modulates Ca2 sparks by a Ca2/calmodulin kinase signalling pathway in rat cardiac myocytes
-
Pereira L, Metrich M, Fernandez-Velasco M, et al. The cAMP binding protein epac modulates Ca2 sparks by a Ca2/calmodulin kinase signalling pathway in rat cardiac myocytes. J Physiol 2007; 583:685-694.
-
(2007)
J Physiol
, vol.583
, pp. 685-694
-
-
Pereira, L.1
Metrich, M.2
Fernandez-Velasco, M.3
-
41
-
-
69549133920
-
The cAMP binding protein epac regulates cardiac myofilament function
-
Cazorla O, Lucas A, Poirier F, et al. The cAMP binding protein epac regulates cardiac myofilament function. Proc Natl Acad Sci U S A 2009; 106:14144-14149.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14144-14149
-
-
Cazorla, O.1
Lucas, A.2
Poirier, F.3
-
42
-
-
33644667603
-
CAMP-binding protein epac induces cardiomyocyte hypertrophy
-
Morel E, Marcantoni A, Gastineau M, et al. cAMP-binding protein epac induces cardiomyocyte hypertrophy. Circ Res 2005; 97:1296-1304.
-
(2005)
Circ Res
, vol.97
, pp. 1296-1304
-
-
Morel, E.1
Marcantoni, A.2
Gastineau, M.3
-
43
-
-
84155186284
-
Epac enhances excitation-transcription coupling in cardiac myocytes
-
Pereira L, Ruiz-Hurtado G, Morel E, et al. Epac enhances excitation-transcription coupling in cardiac myocytes. J Mol Cell Cardiol 2012; 52:283-291.
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 283-291
-
-
Pereira, L.1
Ruiz-Hurtado, G.2
Morel, E.3
-
44
-
-
84927737832
-
Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy
-
Nakano SJ, Miyamoto SD, Movsesian M, et al. Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy. Circ Heart Fail 2015; 8:57-63.
-
(2015)
Circ Heart Fail
, vol.8
, pp. 57-63
-
-
Nakano, S.J.1
Miyamoto, S.D.2
Movsesian, M.3
-
45
-
-
0018948046
-
Selective activation of particulate cAMPdependent protein kinase by isoproterenol and prostaglandin E1
-
Hayes JS, Brunton LL, Mayer SE. Selective activation of particulate cAMPdependent protein kinase by isoproterenol and prostaglandin E1. J Biol Chem 1980; 255:5113-5119.
-
(1980)
J Biol Chem
, vol.255
, pp. 5113-5119
-
-
Hayes, J.S.1
Brunton, L.L.2
Mayer, S.E.3
-
46
-
-
0021023294
-
Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes
-
Buxton IL, Brunton LL. Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes. J Biol Chem 1983; 258:10233-10239.
-
(1983)
J Biol Chem
, vol.258
, pp. 10233-10239
-
-
Buxton, I.L.1
Brunton, L.L.2
-
47
-
-
0036500494
-
Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes
-
Zaccolo M, Pozzan T. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science 2002; 295:1711-1715.
-
(2002)
Science
, vol.295
, pp. 1711-1715
-
-
Zaccolo, M.1
Pozzan, T.2
-
48
-
-
3142723295
-
Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases
-
Mongillo M, McSorley T, Evellin S, et al. Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases. Circ Res 2004; 95:67-75.
-
(2004)
Circ Res
, vol.95
, pp. 67-75
-
-
Mongillo, M.1
McSorley, T.2
Evellin, S.3
-
49
-
-
33646776455
-
A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes
-
Rochais F, Abi-Gerges A, Horner K, et al. A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes. Circ Res 2006; 98:1081-1088.
-
(2006)
Circ Res
, vol.98
, pp. 1081-1088
-
-
Rochais, F.1
Abi-Gerges, A.2
Horner, K.3
-
50
-
-
33644865929
-
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMPdependent pathway
-
Mongillo M, Tocchetti CG, Terrin A, et al. Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMPdependent pathway. Circ Res 2006; 98:226-234.
-
(2006)
Circ Res
, vol.98
, pp. 226-234
-
-
Mongillo, M.1
Tocchetti, C.G.2
Terrin, A.3
-
51
-
-
79954891242
-
CGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholaminedependent signaling in cardiac myocytes
-
Stangherlin A, Gesellchen F, Zoccarato A, et al. cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholaminedependent signaling in cardiac myocytes. Circ Res 2011; 108:929-939.
-
(2011)
Circ Res
, vol.108
, pp. 929-939
-
-
Stangherlin, A.1
Gesellchen, F.2
Zoccarato, A.3
-
52
-
-
66149127296
-
The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4d3
-
Terrenoire C, Houslay MD, Baillie GS, Kass RS. The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4d3. J Biol Chem 2009; 284:9140-9146.
-
(2009)
J Biol Chem
, vol.284
, pp. 9140-9146
-
-
Terrenoire, C.1
Houslay, M.D.2
Baillie, G.S.3
Kass, R.S.4
-
53
-
-
26244467287
-
Phosphodiesterase 4d deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
-
Lehnart SE, Wehrens XH, Reiken S, et al. Phosphodiesterase 4d deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell 2005; 123:25-35.
-
(2005)
Cell
, vol.123
, pp. 25-35
-
-
Lehnart, S.E.1
Wehrens, X.H.2
Reiken, S.3
-
54
-
-
79959940734
-
Phosphodiesterase 4b in the cardiac L-type Ca(2)() channel complex regulates Ca(2)() current and protects against ventricular arrhythmias in mice
-
Leroy J, Richter W, Mika D, et al. Phosphodiesterase 4b in the cardiac L-type Ca(2)() channel complex regulates Ca(2)() current and protects against ventricular arrhythmias in mice. J Clin Invest 2011; 121:2651-2661.
-
(2011)
J Clin Invest
, vol.121
, pp. 2651-2661
-
-
Leroy, J.1
Richter, W.2
Mika, D.3
-
55
-
-
34247105883
-
CAMP-specific phosphodiesterase-4 enzymes in the cardiovascular system: A molecular toolbox for generating compartmentalized cAMP signaling
-
Houslay MD, Baillie GS, Maurice DH. cAMP-specific phosphodiesterase-4 enzymes in the cardiovascular system: A molecular toolbox for generating compartmentalized cAMP signaling. Circ Res 2007; 100:950-966.
-
(2007)
Circ Res
, vol.100
, pp. 950-966
-
-
Houslay, M.D.1
Baillie, G.S.2
Maurice, D.H.3
-
56
-
-
75749117558
-
Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown
-
Houslay MD. Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown. Trends Biochem Sci 2010; 35:91-100.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 91-100
-
-
Houslay, M.D.1
-
57
-
-
0037064111
-
Isoforms of cyclic nucleotide phosphodiesterase PDE3a in cardiac myocytes
-
Wechsler J, Choi YH, Krall J, et al. Isoforms of cyclic nucleotide phosphodiesterase PDE3a in cardiac myocytes. J Biol Chem 2002; 277:38072-38078.
-
(2002)
J Biol Chem
, vol.277
, pp. 38072-38078
-
-
Wechsler, J.1
Choi, Y.H.2
Krall, J.3
-
58
-
-
0034697174
-
Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms
-
Kenan Y, Murata T, Shakur Y, et al. Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms. J Biol Chem 2000; 275:12331-12338.
-
(2000)
J Biol Chem
, vol.275
, pp. 12331-12338
-
-
Kenan, Y.1
Murata, T.2
Shakur, Y.3
-
59
-
-
17744398004
-
Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum
-
Shakur Y, Takeda K, Kenan Y, et al. Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum. J Biol Chem 2000; 275:38749-38761.
-
(2000)
J Biol Chem
, vol.275
, pp. 38749-38761
-
-
Shakur, Y.1
Takeda, K.2
Kenan, Y.3
-
60
-
-
33845708060
-
Protein kinase B/Akt phosphorylation of PDE3a and its role in mammalian oocyte maturation
-
Han SJ, Vaccari S, Nedachi T, et al. Protein kinase B/Akt phosphorylation of PDE3a and its role in mammalian oocyte maturation. EMBO J 2006; 25:5716-5725.
-
(2006)
EMBO J
, vol.25
, pp. 5716-5725
-
-
Han, S.J.1
Vaccari, S.2
Nedachi, T.3
-
61
-
-
28044468841
-
Phosphodiesterase 3a binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428
-
Pozuelo Rubio M, Campbell DG, Morrice NA, Mackintosh C. Phosphodiesterase 3a binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428. Biochem J 2005; 392:163-172.
-
(2005)
Biochem J
, vol.392
, pp. 163-172
-
-
Pozuelo Rubio, M.1
Campbell, D.G.2
Morrice, N.A.3
Mackintosh, C.4
-
62
-
-
66449133397
-
Protein kinase c-mediated phosphorylation and activation of PDE3a regulate cAMP levels in human platelets
-
Hunter RW, Mackintosh C, Hers I. Protein kinase c-mediated phosphorylation and activation of PDE3a regulate cAMP levels in human platelets. J Biol Chem 2009; 284:12339-12348.
-
(2009)
J Biol Chem
, vol.284
, pp. 12339-12348
-
-
Hunter, R.W.1
Mackintosh, C.2
Hers, I.3
-
63
-
-
28244461264
-
Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium
-
Hambleton R, Krall J, Tikishvili E, et al. Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium. J Biol Chem 2005; 280:39168-39174.
-
(2005)
J Biol Chem
, vol.280
, pp. 39168-39174
-
-
Hambleton, R.1
Krall, J.2
Tikishvili, E.3
-
64
-
-
84889660239
-
Selective regulation of cyclic nucleotide phosphodiesterase PDE3a isoforms
-
Vandeput F, Szabo-Fresnais N, Ahmad F, et al. Selective regulation of cyclic nucleotide phosphodiesterase PDE3a isoforms. Proc Natl Acad Sci U S A 2013; 110:19778-19783.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19778-19783
-
-
Vandeput, F.1
Szabo-Fresnais, N.2
Ahmad, F.3
-
65
-
-
84906680068
-
Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling
-
Weninger S, Van Craenenbroeck K, Cameron RT, et al. Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling. Cell Signal 2014; 26:2573-2582.
-
(2014)
Cell Signal
, vol.26
, pp. 2573-2582
-
-
Weninger, S.1
Van Craenenbroeck, K.2
Cameron, R.T.3
-
66
-
-
84928547164
-
Regulation of SERCA2 activity by PDE3a in human myocardium: Phosphorylation-dependent interaction of PDE3a1 with SERCA2
-
Epub ahead of print
-
Ahmad F, Shen W, Vandeput F, et al. Regulation of SERCA2 activity by PDE3a in human myocardium: phosphorylation-dependent interaction of PDE3a1 with SERCA2. J Biol Chem 2015. [Epub ahead of print
-
(2015)
J Biol Chem
-
-
Ahmad, F.1
Shen, W.2
Vandeput, F.3
-
67
-
-
84879784821
-
Targeting protein-protein interactions as an anticancer strategy
-
Ivanov AA, Khuri FR, Fu H. Targeting protein-protein interactions as an anticancer strategy. Trends Pharmacol Sci 2013; 34:393-400.
-
(2013)
Trends Pharmacol Sci
, vol.34
, pp. 393-400
-
-
Ivanov, A.A.1
Khuri, F.R.2
Fu, H.3
-
68
-
-
79957876717
-
Conserved expression and functions of PDE4 in rodent and human heart
-
Richter W, Xie M, Scheitrum C, et al. Conserved expression and functions of PDE4 in rodent and human heart. Basic Res Cardiol 2011; 106:249-262.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 249-262
-
-
Richter, W.1
Xie, M.2
Scheitrum, C.3
-
69
-
-
36348933827
-
Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes
-
Vandeput F, Wolda SL, Krall J, et al. Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes. J Biol Chem 2007; 282:32749-32757.
-
(2007)
J Biol Chem
, vol.282
, pp. 32749-32757
-
-
Vandeput, F.1
Wolda, S.L.2
Krall, J.3
-
70
-
-
70349085833
-
CGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium
-
Vandeput F, Krall J, Ockaili R, et al. cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. J Pharmacol Exp Ther 2009; 330:884-891.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 884-891
-
-
Vandeput, F.1
Krall, J.2
Ockaili, R.3
-
71
-
-
72449174812
-
Role of Ca2/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy
-
Miller CL, Oikawa M, Cai Y, et al. Role of Ca2/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. Circ Res 2009; 105:956-964.
-
(2009)
Circ Res
, vol.105
, pp. 956-964
-
-
Miller, C.L.1
Oikawa, M.2
Cai, Y.3
-
72
-
-
84857367841
-
Profiling of cAMP and cGMP phosphodiesterases in isolated ventricular cardiomyocytes from human hearts: Comparison with rat and guinea pig
-
Johnson WB, Katugampola S, Able S, et al. Profiling of cAMP and cGMP phosphodiesterases in isolated ventricular cardiomyocytes from human hearts: comparison with rat and guinea pig. Life Sci 2012; 90:328-336.
-
(2012)
Life Sci
, vol.90
, pp. 328-336
-
-
Johnson, W.B.1
Katugampola, S.2
Able, S.3
-
73
-
-
84901196872
-
Repetitive use of levosimendan for treatment of chronic advanced heart failure: Clinical evidence, practical considerations, and perspectives: An expert panel consensus
-
Nieminen MS, Altenberger J, Ben-Gal T, et al. Repetitive use of levosimendan for treatment of chronic advanced heart failure: clinical evidence, practical considerations, and perspectives: An expert panel consensus. Int J Cardiol 2014; 174:360-367.
-
(2014)
Int J Cardiol
, vol.174
, pp. 360-367
-
-
Nieminen, M.S.1
Altenberger, J.2
Ben-Gal, T.3
-
74
-
-
84925851917
-
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
-
Orstavik O, Ata SH, Riise J, et al. Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart. Br J Pharmacol 2014; 171:5169-5181.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 5169-5181
-
-
Orstavik, O.1
Ata, S.H.2
Riise, J.3
|