Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets

Journal of Biological Chemistry

Volumn 284, Issue 18, 2009, Pages 12339-12348

  Hunter, Roger W ^a   MacKintosh, Carol ^b   Hers, Ingeborg ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

14-3-3 PROTEINS; ADENYLYL CYCLASE; FORSKOLIN; PHORBOL ESTERS; PHOSPHODIESTERASE; PLATELET ACTIVATION; PLATELET AGONISTS; PROTEIN KINASE C;

BLOOD SUBSTITUTES; ESTERS; FETAL MONITORING; PLATELETS;

PHOSPHORYLATION;

CYCLIC AMP; FORSKOLIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IIIA; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN KINASE C; S6 KINASE; SERINE DERIVATIVE; THROMBIN; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; HEMOSTATIC AGENT; PDE3A PROTEIN, HUMAN; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; PLASMA PROTEIN; PLATELET PROTEIN P47; PROSTAGLANDIN E1; PROTEIN 14 3 3; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN RECEPTOR PEPTIDE (42 47); THROMBIN RECEPTOR PEPTIDE (42-47);

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDROLYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING;

14-3-3 PROTEINS; ALPROSTADIL; BLOOD PLATELETS; BLOOD PROTEINS; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; ENZYME ACTIVATION; HEMOSTATICS; HUMANS; HYDROLYSIS; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; PROTEIN KINASE C; RECEPTOR, PAR-1; THROMBIN;

EID: 66449133397     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807536200     Document Type: Article

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