Efficient co-delivery of a Pt(iv) prodrug and a p53 activator to enhance the anticancer activity of cisplatin

Chemical Communications

Volumn 51, Issue 37, 2015, Pages 7859-7862

  Ma, Rong ^a   Wang, Yiping ^a   Yan, Li ^a   Ma, Lili ^a   Wang, Zhigang ^a   Chan, Hoi Ching ^a   Chiu, Sung Kay ^a   Chen, Xianfeng ^a   Zhu, Guangyu ^a  

^a CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DISUCCINATOCISPLATIN; DNA; GENOMIC DNA; HYDROXIDE; NANOPARTICLE; P53 ACTIVATOR; PRODRUG; PROTEIN P53; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MDM2 PROTEIN, MOUSE; PLATINUM COMPLEX; PROTEIN MDM2;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL KILLING; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; MTT ASSAY; AGONISTS; ANIMAL; APOPTOSIS; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; MCF 7 CELL LINE; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MCF-7 CELLS; MICE; ORGANOPLATINUM COMPOUNDS; PRODRUGS; PROTO-ONCOGENE PROTEINS C-MDM2; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84928532227     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c4cc09879j     Document Type: Article

References (24)

1. N. J. Wheate S. Walker G. E. Craig R. Oun Dalton Trans. 2010 39 8113
2. D. Wang S. J. Lippard Nat. Rev. Drug Discovery 2005 4 307
3. T. Soussi Ann. N. Y. Acad. Sci. 2000 910 121
4. P. Bragado A. Armesilla A. Silva A. Porras Apoptosis 2007 12 1733
5. S. Benchimol Cell Death Differ. 2001 8 1049
6. A. Vekris D. Meynard M.-C. Haaz M. Bayssas J. Bonnet J. Robert Cancer Res. 2004 64 356
7. P. Perego M. Giarola S. C. Righetti R. Supino C. Caserini D. Delia M. A. Pierotti T. Miyashita J. C. Reed F. Zunino Cancer Res. 1996 56 556
8. P. Chène Nat. Rev. Cancer 2003 3 102
9. S. Shangary S. Wang Annu. Rev. Pharmacol. Toxicol. 2009 49 223
10. L. Li W. Gu J. Chen W. Chen Z. P. Xu Biomaterials 2014 35 3331
11. R. Ma Z. Wang L. Yan X. Chen G. Zhu J. Mater. Chem. B 2014 2 4868
12. S. J. Choi J.-M. Oh J.-H. Choy J. Nanosci. Nanotechnol. 2010 10 2913
13. C. Klein L. Vassilev Br. J. Cancer 2004 91 1415
14. M. Trikeriotis D. F. Ghanotakis Int. J. Pharm. 2007 332 176
15. F. Bois A. Boumendjel A.-M. Mariotte G. Conseil A. Di Petro Bioorg. Med. Chem. 1999 7 2691
16. Z. P. Xu G. Lu Pure Appl. Chem. 2006 78 1771
17. C. C. Cain D. M. Sipe R. F. Murphy Proc. Natl. Acad. Sci. U. S. A. 1989 86 544
18. S.-J. Choi J.-M. Oh J.-H. Choy J. Phys. Chem. Solids 2008 69 1528
19. L. D. Attardi A. de Vries T. Jacks Oncogene 2004 23 973
20. N. S. Pellegata R. J. Antoniono J. L. Redpath E. J. Stanbridge Proc. Natl. Acad. Sci. U. S. A. 1996 93 15209
21. F. Tadini-Buoninsegni G. Bartolommei M. R. Moncelli G. Inesi A. Galliani M. Sinisi M. Losacco G. Natile F. Arnesano Angew. Chem., Int. Ed. 2014 53 1297
22. L. Banci I. Bertini O. BlaževitŠ V. Calderone F. Cantini J. Mao A. Trapananti M. Vieru I. Amori M. Cozzolino M. T. Carrì J. Am. Chem. Soc. 2012 134 7009
23. V. Calderone A. Casini S. Mangani L. Messori P. L. Orioli Angew. Chem., Int. Ed. 2006 45 1267
24. A. Casini J. Reedijk Chem. Sci. 2012 3 3135