Visceral adipose tissue is associated with microstructural brain tissue damage

Obesity

Volumn 23, Issue 5, 2015, Pages 1092-1096

  Widya, Ralph L ^a   Kroft, Lucia J M ^a   Altmann Schneider, Irmhild ^a,b   Van Den Berg Huysmans, Annette A ^a   Van Der Bijl, Noortje ^a   De Roos, Albert ^a   Lamb, Hildo J ^a   Van Buchem, Mark A ^a,b   Slagboom, P Eline ^a,b   Van Heemst, Diana ^a,b   Van Der Grond, Jeroen ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Consortium for Healthy Ageing   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BRAIN DAMAGE; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; HUMAN TISSUE; IMAGING AND DISPLAY; INTRAABDOMINAL FAT; MAGNETIZATION TRANSFER RATIO; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; SUBCUTANEOUS FAT; WHITE MATTER; BRAIN; COMPLICATION; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOLOGY; REGRESSION ANALYSIS; ULTRASTRUCTURE; VERY ELDERLY;

BIOLOGICAL MARKER;

AGED; AGED, 80 AND OVER; BIOMARKERS; BRAIN; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INTRA-ABDOMINAL FAT; MALE; MIDDLE AGED; OBESITY; REGRESSION ANALYSIS; SUBCUTANEOUS FAT;

EID: 84928530811     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.21048     Document Type: Article

References (40)

1. Raji CA, Ho AJ, Parikshak NN, et al. Brain structure and obesity. Hum Brain Mapp 2010; 31: 353-364.
2. Taki Y, Kinomura S, Sato K, et al. Relationship between body mass index and gray matter volume in 1,428 healthy individuals. Obesity (Silver Spring) 2008; 16: 119-124.
3. Sala M, de Roos A, van den Berg A, et al. Microstructural brain tissue damage in metabolic syndrome. Diabetes Care 2014; 37: 493-500.
4. Sluimer JD, van der Flier WM, Karas GB, et al. Whole-brain atrophy rate and cognitive decline: longitudinal MR study of memory clinic patients. Radiology 2008; 248: 590-598.
5. Mathieu P, Lemieux I, Despres JP,. Obesity, inflammation, and cardiovascular risk. Clin Pharmacol Ther 2010; 87: 407-416.
6. Britton KA, Massaro JM, Murabito JM, Kreger BE, Hoffmann U, Fox CS,. Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality. J Am Coll Cardiol 2013; 62: 921-925.
7. Pou KM, Massaro JM, Hoffmann U, Vasan RS, et al. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007; 116: 1234-1241.
8. Debette S, Beiser A, Hoffmann U, et al. Visceral fat is associated with lower brain volume in healthy middle-aged adults. Ann Neurol 2010; 68: 136-144.
9. Inglese M, Ge Y,. Quantitative MRI: hidden age-related changes in brain tissue. Top Magn Reson Imaging 2004; 15: 355-363.
10. Seiler S, Cavalieri M, Schmidt R,. Vascular cognitive impairment-an ill-defined concept with the need to define its vascular component. J Neurol Sci 2012; 322: 11-16.
11. van Buchem MA, McGowan JC, Grossman RI,. Magnetization transfer histogram methodology: its clinical and neuropsychological correlates. Neurology 1999; 53: S23-S28.
12. Henkelman RM, Stanisz GJ, Graham SJ,. Magnetization transfer in MRI: a review. NMR Biomed 2001; 14: 57-64.
13. Filippi M, Rocca MA,. Magnetization transfer magnetic resonance imaging of the brain, spinal cord, and optic nerve. Neurotherapeutics 2007; 4: 401-413.
14. Schoenmaker M, de Craen AJ, de Meijer PH, et al. Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study. Eur J Hum Genet 2006; 14: 79-84.
15. Westendorp RG, van Heemst D, Rozing MP, et al. Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: the Leiden Longevity Study. J Am Geriatr Soc 2009; 57: 1634-1637.
16. Altmann-Schneider I, de Craen AJ, Slagboom PE, et al. Brain tissue volumes in familial longevity: the Leiden Longevity Study. Aging Cell 2012; 11: 933-939.
17. Smith SM, Jenkinson M, Woolrich MW, et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23 Suppl 1: S208-S219.
18. Woolrich MW, Jbabdi S, Patenaude B, et al. Bayesian analysis of neuroimaging data in FSL. Neuroimage 2009; 45: S173-S186.
19. Smith SM,. Fast robust automated brain extraction. Hum Brain Mapp 2002; 17: 143-155.
20. Zhang Y, Brady M, Smith S,. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging 2001; 20: 45-57.
21. Jagust W, Harvey D, Mungas D, Haan M,. Central obesity and the aging brain. Arch Neurol 2005; 62: 1545-1548.
22. Karcher HS, Holzwarth R, Mueller HP, et al. Body fat distribution as a risk factor for cerebrovascular disease: an MRI-based body fat quantification study. Cerebrovasc Dis 2013; 35: 341-348.
23. Yamashiro K, Tanaka R, Tanaka Y, et al. Visceral fat accumulation is associated with cerebral small vessel disease. Eur J Neurol 2014; 21: 667-673.
24. Isaac V, Sim S, Zheng H, Zagorodnov V, Tai ES, Chee M,. Adverse associations between visceral adiposity, brain structure, and cognitive performance in healthy elderly. Front Aging Neurosci 2011; 3: 12.
25. Dehmeshki J, Chard DT, Leary SM, et al. The normal appearing grey matter in primary progressive multiple sclerosis: a magnetisation transfer imaging study. J Neurol 2003; 250: 67-74.
26. Grossman RI, Gomori JM, Ramer KN, Lexa FJ, Schnall MD,. Magnetization transfer: theory and clinical applications in neuroradiology. Radiographics 1994; 14: 279-290.
27. Wozniak JR, Lim KO,. Advances in white matter imaging: a review of in vivo magnetic resonance methodologies and their applicability to the study of development and aging. Neurosci Biobehav Rev 2006; 30: 762-774.
28. Holland PR, Bastin ME, Jansen MA, et al. MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice. Neurobiol Aging 2011; 32: 2325-2326.
29. Song SK, Sun SW, Ramsbottom MJ, Chang C, Russell J, Cross AH,. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002; 17: 1429-1436.
30. Bosma GP, Rood MJ, Zwinderman AH, Huizinga TW, van Buchem MA,. Evidence of central nervous system damage in patients with neuropsychiatric systemic lupus erythematosus, demonstrated by magnetization transfer imaging. Arthritis Rheum 2000; 43: 48-54.
31. Ropele S, Enzinger C, Sollinger M, et al. The impact of sex and vascular risk factors on brain tissue changes with aging: magnetization transfer imaging results of the Austrian stroke prevention study. AJNR Am J Neuroradiol 2010; 31: 1297-1301.
32. van den Bogaard SJ, Dumas EM, Milles J, et al. Magnetization transfer imaging in premanifest and manifest Huntington disease. AJNR Am J Neuroradiol 2012; 33: 884-889.
33. Benedetti B, Charil A, Rovaris M, et al. Influence of aging on brain gray and white matter changes assessed by conventional, MT, and DT MRI. Neurology 2006; 66: 535-539.
34. Ropele S, Schmidt R, Enzinger C, Windisch M, Martinez NP, Fazekas F,. Longitudinal magnetization transfer imaging in mild to severe Alzheimer disease. AJNR Am J Neuroradiol 2012; 33: 570-575.
35. van Es AC, van der Flier WM, Admiraal-Behloul F, et al. Lobar distribution of changes in gray matter and white matter in memory clinic patients: detected using magnetization transfer imaging. AJNR Am J Neuroradiol 2007; 28: 1938-1942.
36. Després JP, Lemieux I,. Abdominal obesity and metabolic syndrome. Nature 2006; 444: 881-887.
37. Wajchenberg BL,. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocrinol Rev 2000; 21: 697-738.
38. Masquio DC, de Piano A, Sanches PL, et al. The effect of weight loss magnitude on pro-/anti-inflammatory adipokines and carotid intima-media thickness in obese adolescents engaged in interdisciplinary weight loss therapy. Clin Endocrinol (Oxf) 2013; 79: 55-64.
39. Cooper JN, Buchanich JM, Youk A, et al. Reductions in arterial stiffness with weight loss in overweight and obese young adults: potential mechanisms. Atherosclerosis 2012; 223: 485-490.
40. Yau PL, Castro MG, Tagani A, Tsui WH, Convit A,. Obesity and metabolic syndrome and functional and structural brain impairments in adolescence. Pediatrics 2012; 130: 1-9.