Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality

Journal of the American College of Cardiology

Volumn 62, Issue 10, 2013, Pages 921-925

  Britton, Kathryn A ^a,b   Massaro, Joseph M ^c   Murabito, Joanne M ^a,d   Kreger, Bernard E ^a,d   Hoffmann, Udo ^e   Fox, Caroline S ^a,b,f  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b FRAMINGHAM HEART STUDY   (United States)

^c Boston University   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

body fat distribution; cancer; cardiovascular disease; obesity; visceral fat

Indexed keywords

ABDOMINAL OBESITY; ADIPOSE TISSUE; ADULT; ALL CAUSE MORTALITY; ARTICLE; BODY FAT DISTRIBUTION; BODY MASS; CANCER RISK; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; INTRAABDOMINAL FAT; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; MULTIDETECTOR COMPUTED TOMOGRAPHY; OUTCOME ASSESSMENT; PERIAORTIC FAT; PERICARDIAL FAT; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE; WAIST CIRCUMFERENCE;

BMI; BODY FAT DISTRIBUTION; BODY MASS INDEX; CANCER; CARDIOVASCULAR DISEASE; CI; CONFIDENCE INTERVAL; CVD; HAZARD RATIO; HR; MDCT; MULTIDETECTOR COMPUTED TOMOGRAPHY; NET RECLASSIFICATION INDEX; NRI; OBESITY; SAT; SUBCUTANEOUS ADIPOSE TISSUE; VAT; VISCERAL ADIPOSE TISSUE; VISCERAL FAT;

ADULT; AGED; BODY FAT DISTRIBUTION; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; NEOPLASMS; OBESITY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS;

EID: 84883226091     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.06.027     Document Type: Article

References (17)

1. A.A. Mahabadi, J.M. Massaro, and G.A. Rosito Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study Eur Heart J 30 2009 850 856
2. T. Yamaji, M. Iwasaki, and S. Sasazuki Visceral fat volume and the prevalence of colorectal adenoma Am J Epidemiol 170 2009 1502 1511
3. A.S. Greenstein, K. Khavandi, and S.B. Withers Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients Circulation 119 2009 1661 1670
4. C.S. Fox, J.M. Massaro, and C.L. Schlett Peri-aortic fat deposition is associated with peripheral arterial disease: The Framingham Heart Study Circ Cardiovasc Imaging 3 2010 515 519
5. G.A. Rosito, J.M. Massaro, and U. Hoffmann Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study Circulation 117 2008 605 613
6. V.Y. Cheng, D. Dey, and B. Tamarappoo Pericardial fat burden on ECG-gated noncontrast CT in asymptomatic patients who subsequently experience adverse cardiovascular events J Am Coll Cardiol Img 3 2010 352 360
7. J. Ding, F.-C. Hsu, and T.B. Harris The association of pericardial fat with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA) Am J Clin Nutr 90 2009 499 504
8. J.L. Kuk, P.T. Katzmarzyk, M.Z. Nichaman, T.S. Church, S.N. Blair, and R. Ross Visceral fat is an independent predictor of all-cause mortality in men Obesity 14 2006 336 341
9. B.J. Nicklas, B.W.J.H. Penninx, and M. Cesari Association of visceral adipose tissue with incident myocardial infarction in older men and women Am J Epidemiol 160 2004 741 749
10. C.S. Fox, J.M. Massaro, and U. Hoffmann Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study Circulation 116 2007 39 48
11. N.R. Cook, and P.M. Ridker Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures Ann Intern Med 150 2009 795 802
12. J.C. Lovejoy, A. Sainsbury the Stock Conference Working Group Sex differences in obesity and the regulation of energy homeostasis Obes Rev 10 2009 154 167
13. M.J. McNeely, J.B. Shofer, D.L. Leonetti, W.Y. Fujimoto, and E.J. Boyko Associations among visceral fat, all-cause mortality, and obesity-related mortality in Japanese Americans Diabetes Care 35 2012 296 298
14. The Emerging Risk Factors Collaboration Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies Lancet 377 2011 1085 1095
15. N. Ouchi, J.L. Parker, J.J. Lugus, and K. Walsh Adipokines in inflammation and metabolic disease Nat Rev Immunol 11 2011 85 97
16. S.L. Hocking, L.E. Wu, M. Guilhaus, D.J. Chisholm, and D.E. James Intrinsic depot-specific differences in the secretome of adipose tissue, preadipocytes, and adipose tissue-derived microvascular endothelial cells Diabetes 59 2010 3008 3016
17. M.G. Farb, L. Ganley-Leal, and M. Mott Arteriolar function in visceral adipose tissue is impaired in human obesity Arterioscler Thromb Vasc Biol 32 2012 467 473