Vascular cognitive impairment - An ill-defined concept with the need to define its vascular component

Journal of the Neurological Sciences

Volumn 322, Issue 1-2, 2012, Pages 11-16

  Seiler, Stephan ^a   Cavalieri, Margherita ^a   Schmidt, Reinhold ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Lacunes; Magnetic resonance imaging; Microbleeds; Normal appearing brain tissue; Vascular cognitive impairment; White matter lesions

Indexed keywords

ARTICLE; BRAIN ATROPHY; BRAIN DAMAGE; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; BRAIN VENTRICLE; CADASIL; CLINICAL TRIAL (TOPIC); COGNITIVE DEFECT; CORRELATION ANALYSIS; COVARIANCE; DEGENERATIVE DISEASE; DEMENTIA; DIFFUSION TENSOR IMAGING; DISEASE COURSE; GLIOSIS; HISTOPATHOLOGIC SKIN REACTION; HISTOPATHOLOGY; HUMAN; IMAGE PROCESSING; INCIDENCE; LACUNAR STROKE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VASCULAR AMYLOIDOSIS; VASCULAR COGNITIVE IMPAIRMENT; VOXEL BASED LESION SYMPTOM MAPPING; VOXEL BASED MORPHOMETRY; WECHSLER INTELLIGENCE SCALE; WHITE MATTER; WHITE MATTER LESION;

BRAIN; CEREBROVASCULAR DISORDERS; COGNITION DISORDERS; DISEASE PROGRESSION; HUMANS; MAGNETIC RESONANCE IMAGING; NERVE FIBERS, MYELINATED;

EID: 84867575291     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.06.001     Document Type: Article

References (58)

1. R.N. Kalaria, and C. Ballard Overlap between pathology of Alzheimer disease and vascular dementia Alzheimer Dis Assoc Disord 13 Suppl. 3 Oct-Dec 1999 S115 S123
2. L. Wahlund, T. Erkinjuntti, and S. Gauthier Vascular cognitive impairment in clinical practice 2009 Cambridge University Press
3. P.B. Gorelick, A. Scuteri, S.E. Black, C. Decarli, S.M. Greenberg, and C. Iadecola Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke 42 9 Sep 2011 2672 2713
4. M.I. Chimowitz, M.L. Estes, A.J. Furlan, and I.A. Awad Further observations on the pathology of subcortical lesions identified on magnetic resonance imaging Arch Neurol 49 7 Jul 1992 747 752
5. F. Fazekas, R. Kleinert, H. Offenbacher, F. Payer, R. Schmidt, and G. Kleinert The morphologic correlate of incidental punctate white matter hyperintensities on MR images AJNR Am J Neuroradiol 12 5 Sep-Oct 1991 915 921
6. F. Fazekas, R. Kleinert, H. Offenbacher, R. Schmidt, G. Kleinert, and F. Payer Pathologic correlates of incidental MRI white matter signal hyperintensities Neurology 43 9 Sep 1993 1683 1689
7. D.G. Munoz, S.M. Hastak, B. Harper, D. Lee, and V.C. Hachinski Pathologic correlates of increased signals of the centrum ovale on magnetic resonance imaging Arch Neurol 50 5 May 1993 492 497
8. R. Schmidt, K. Petrovic, S. Ropele, C. Enzinger, and F. Fazekas Progression of leukoaraiosis and cognition Stroke 38 9 Sep 2007 2619 2625
9. N.D. Prins, E.J. van Dijk, T. den Heijer, S.E. Vermeer, P.J. Koudstaal, and M. Oudkerk Cerebral white matter lesions and the risk of dementia Arch Neurol 61 10 Oct 2004 1531 1534
10. E.J. van Dijk, N.D. Prins, H.A. Vrooman, A. Hofman, P.J. Koudstaal, and M.M. Breteler Progression of cerebral small vessel disease in relation to risk factors and cognitive consequences: Rotterdam scan study Stroke 39 10 Oct 2008 2712 2719
11. K. Prasad, L. Wiryasaputra, A. Ng, and N. Kandiah White matter disease independently predicts progression from mild cognitive impairment to Alzheimer's disease in a clinic cohort Dement Geriatr Cogn Disord 31 6 2011 431 434
12. C.M. Fisher Lacunes: small, deep cerebral infarcts Neurology 15 Aug 1965 774 784
13. S. Benisty, A.A. Gouw, R. Porcher, S. Madureira, K. Hernandez, and A. Poggesi Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study J Neurol Neurosurg Psychiatry 80 5 May 2009 478 483
14. H. Jokinen, A.A. Gouw, S. Madureira, R. Ylikoski, E.C. van Straaten, and W.M. van der Flier Incident lacunes influence cognitive decline: the LADIS study Neurology 76 22 May 31, 2011 1872 1878
15. E. Bates, S.M. Wilson, A.P. Saygin, F. Dick, M.I. Sereno, and R.T. Knight Voxel-based lesion-symptom mapping Nat Neurosci 6 5 May 2003 448 450
16. M. Duering, N. Zieren, D. Herve, E. Jouvent, S. Reyes, and N. Peters Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL Brain 134 Pt 8 Aug 2011 2366 2375
17. S.M. Greenberg, M.W. Vernooij, C. Cordonnier, A. Viswanathan, R. Al-Shahi Salman, and S. Warach Cerebral microbleeds: a guide to detection and interpretation Lancet Neurol 8 2 Feb 2009 165 174
18. F. Fazekas, R. Kleinert, G. Roob, G. Kleinert, P. Kapeller, and R. Schmidt Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds AJNR Am J Neuroradiol 20 4 Apr 1999 637 642
19. C. Cordonnier, W.M. van der Flier, J.D. Sluimer, D. Leys, F. Barkhof, and P. Scheltens Prevalence and severity of microbleeds in a memory clinic setting Neurology 66 9 May 9, 2006 1356 1360
20. J.D. Goos, W.J. Henneman, J.D. Sluimer, H. Vrenken, I.C. Sluimer, and F. Barkhof Incidence of cerebral microbleeds: a longitudinal study in a memory clinic population Neurology 74 24 Jun 15, 2010 1954 1960
21. M.M. Poels, M.A. Ikram, A. van der Lugt, A. Hofman, G.P. Krestin, and M.M. Breteler Incidence of cerebral microbleeds in the general population: the Rotterdam scan study Stroke 42 3 Mar 2011 656 661
22. M.M. Poels, M.A. Ikram, A. van der Lugt, A. Hofman, W.J. Niessen, and G.P. Krestin Cerebral microbleeds are associated with worse cognitive function: the Rotterdam scan study Neurology 78 5 2012 326 333
23. S.J. Graham, and R.M. Henkelman Understanding pulsed magnetization transfer J Magn Reson Imaging 7 5 Sep-Oct 1997 903 912
24. S. Mori, and J. Zhang Principles of diffusion tensor imaging and its applications to basic neuroscience research Neuron 51 5 Sep 7, 2006 527 539
25. R.M. Henkelman, G.J. Stanisz, and S.J. Graham Magnetization transfer in MRI: a review NMR Biomed 14 2 Apr 2001 57 64
26. P. Mukherjee, J.I. Berman, S.W. Chung, C.P. Hess, and R.G. Henry Diffusion tensor MR imaging and fiber tractography: theoretic underpinnings AJNR Am J Neuroradiol 29 4 Apr 2008 632 641
27. P. Mukherjee, S.W. Chung, J.I. Berman, C.P. Hess, and R.G. Henry Diffusion tensor MR imaging and fiber tractography: technical considerations AJNR Am J Neuroradiol 29 5 May 2008 843 852
28. R.A. Bhadelia, L.L. Price, K.L. Tedesco, T. Scott, W.Q. Qiu, and S. Patz Diffusion tensor imaging, white matter lesions, the corpus callosum, and gait in the elderly Stroke 40 12 Dec 2009 3816 3820
29. F.M. Gunning-Dixon, A.M. Brickman, J.C. Cheng, and G.S. Alexopoulos Aging of cerebral white matter: a review of MRI findings Int J Geriatr Psychiatry 24 2 Feb 2009 109 117
30. M. O'Sullivan, R.G. Morris, B. Huckstep, D.K. Jones, S.C. Williams, and H.S. Markus Diffusion tensor MRI correlates with executive dysfunction in patients with ischaemic leukoaraiosis J Neurol Neurosurg Psychiatry 75 3 Mar 2004 441 447
31. C. Rosano, S. Sigurdsson, K. Siggeirsdottir, C.L. Phillips, M. Garcia, and P.V. Jonsson Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women Neurobiol Aging 31 7 Jul 2010 1197 1204
32. R. Schmidt, S. Ropele, J. Ferro, S. Madureira, A. Verdelho, and K. Petrovic Diffusion-weighted imaging and cognition in the leukoariosis and disability in the elderly study Stroke 41 5 May 2010 e402 e408
33. M. Viana-Baptista, P. Bugalho, C. Jordao, N. Ferreira, A. Ferreira, and M. Forjaz Secca Cognitive function correlates with frontal white matter apparent diffusion coefficients in patients with leukoaraiosis J Neurol 255 3 Mar 2008 360 366
34. K. Schmierer, D.R. Altmann, N. Kassim, H. Kitzler, C.M. Kerskens, and C.A. Doege Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study Mult Scler 10 2 Apr 2004 182 187
35. S.D. Shenkin, M.E. Bastin, T.J. Macgillivray, I.J. Deary, J.M. Starr, and C.S. Rivers Cognitive correlates of cerebral white matter lesions and water diffusion tensor parameters in community-dwelling older people Cerebrovasc Dis 20 5 2005 310 318
36. L. Wang, F.C. Goldstein, A.I. Levey, J.J. Lah, C.C. Meltzer, and C.A. Holder White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease Neuroradiology 53 5 May 2011 373 381
37. V. Srikanth, T.G. Phan, J. Chen, R. Beare, J.M. Stapleton, and D.C. Reutens The location of white matter lesions and gait - a voxel-based study Ann Neurol 67 2 Feb 2010 265 269
38. A. Yendiki, P. Panneck, P. Srinivasan, A. Stevens, L. Zollei, and J. Augustinack Automated probabilistic reconstruction of white-matter pathways in health and disease using an atlas of the underlying anatomy Front Neuroinform 5 2011 23
39. E. Jouvent, C. Poupon, F. Gray, C. Paquet, J.F. Mangin, and D. Le Bihan Intracortical infarcts in small vessel disease: a combined 7-T postmortem MRI and neuropathological case study in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy Stroke 42 3 Mar 2011 e27 e30
40. M.S. Fernando, J.E. Simpson, F. Matthews, C. Brayne, C.E. Lewis, and R. Barber White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury Stroke 37 6 Jun 2006 1391 1398
41. W.T. Longstreth Jr., A.M. Arnold, N.J. Beauchamp Jr., T.A. Manolio, D. Lefkowitz, and C. Jungreis Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study Stroke 36 1 Jan 2005 56 61
42. E. Garde, E.L. Mortensen, K. Krabbe, E. Rostrup, and H.B. Larsson Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study Lancet 356 9230 Aug 19, 2000 628 634
43. D.M. van den Heuvel, V.H. ten Dam, A.J. de Craen, F. Admiraal-Behloul, H. Olofsen, and E.L. Bollen Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population J Neurol Neurosurg Psychiatry 77 2 Feb 2006 149 153
44. R. Schmidt, S. Ropele, C. Enzinger, K. Petrovic, S. Smith, and H. Schmidt White matter lesion progression, brain atrophy, and cognitive decline: the Austrian stroke prevention study Ann Neurol 58 4 Oct 2005 610 616
45. J.H. Kramer, D. Mungas, B.R. Reed, M.E. Wetzel, M.M. Burnett, and B.L. Miller Longitudinal MRI and cognitive change in healthy elderly Neuropsychology 21 4 Jul 2007 412 418
46. L.C. Silbert, C. Nelson, D.B. Howieson, M.M. Moore, and J.A. Kaye Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline Neurology 71 2 Jul 8, 2008 108 113
47. A.A. Gouw, W.M. van der Flier, F. Fazekas, E.C. van Straaten, L. Pantoni, and A. Poggesi Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the leukoaraiosis and disability study Stroke 39 5 May 2008 1414 1420
48. X. Chen, W. Wen, K.J. Anstey, and P.S. Sachdev Prevalence, incidence, and risk factors of lacunar infarcts in a community sample Neurology 73 4 Jul 28, 2009 266 272
49. D.J. Werring, D.W. Frazer, L.J. Coward, N.A. Losseff, H. Watt, and L. Cipolotti Cognitive dysfunction in patients with cerebral microbleeds on T2*-weighted gradient-echo MRI Brain 127 Pt 10 Oct 2004 2265 2275
50. A. Viswanathan, O. Godin, E. Jouvent, M. O'Sullivan, A. Gschwendtner, and N. Peters Impact of MRI markers in subcortical vascular dementia: a multi-modal analysis in CADASIL Neurobiol Aging 31 9 Sep 2010 1629 1636
51. J.A. Pettersen, G. Sathiyamoorthy, F.Q. Gao, G. Szilagyi, N.K. Nadkarni, and P. St George-Hyslop Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study Arch Neurol 65 6 Jun 2008 790 795
52. Y. Yakushiji, M. Nishiyama, S. Yakushiji, T. Hirotsu, A. Uchino, and J. Nakajima Brain microbleeds and global cognitive function in adults without neurological disorder Stroke 39 12 Dec 2008 3323 3328
53. M.K. Liem, S.A. Lesnik Oberstein, J. Haan, I.L. van der Neut, M.D. Ferrari, and M.A. van Buchem MRI correlates of cognitive decline in CADASIL: a 7-year follow-up study Neurology 72 2 Jan 13, 2009 143 148
54. C. Qiu, M.F. Cotch, S. Sigurdsson, P.V. Jonsson, M.K. Jonsdottir, and S. Sveinbjrnsdottir Cerebral microbleeds, retinopathy, and dementia: the AGES-Reykjavik study Neurology 75 24 Dec 14, 2010 2221 2228
55. A.G. van Norden, H.A. van den Berg, K.F. de Laat, R.A. Gons, E.J. van Dijk, and F.E. de Leeuw Frontal and temporal microbleeds are related to cognitive function: the Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) study Stroke 42 12 Dec 2011 3382 3386
56. H. Chabriat, S. Pappata, C. Poupon, C.A. Clark, K. Vahedi, and F. Poupon Clinical severity in CADASIL related to ultrastructural damage in white matter: in vivo study with diffusion tensor MRI Stroke 30 12 Dec 1999 2637 2643
57. F. Fazekas, S. Ropele, C. Enzinger, F. Gorani, A. Seewann, and K. Petrovic MTI of white matter hyperintensities Brain 128 Pt 12 Dec 2005 2926 2932
58. D.Y. Lee, E. Fletcher, O. Martinez, M. Ortega, N. Zozulya, and J. Kim Regional pattern of white matter microstructural changes in normal aging, MCI, and AD Neurology 73 21 Nov 24, 2009 1722 1728