Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Cristóbal García, Magdalena ^a   García Arroyo, Fernando E ^a,b   Tapia, Edilia ^a,b   Osorio, Horacio ^a,b   Arellano Buendía, Abraham S ^a,b   Madero, Magdalena ^a   Rodríguez Iturbe, Bernardo ^c   Pedraza Chaverrí, José ^d   Correa, Francisco ^a   Zazueta, Cecilia ^a   Johnson, Richard J ^e   Sánchez Lozada, Laura Gabriela ^a,b  

^a Department of Nephrology INC Ignacio Chávez ^*  (Mexico)

^b Laboratory of Renal Physiopathology and Department of Nephrology   (Mexico)

^c HOSPITAL UNIVERSITARIO DE MARACAIBO   (Venezuela)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD PRESSURE; MITOCHONDRIA; POTABLE WATER;

MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL FUNCTION; OXIDATIVE STRESS MARKERS; OXYGEN CONSUMPTION; PATHOGENIC MECHANISMS; PROTEIN OXIDATION; RENAL BLOOD FLOW; SYSTOLIC BLOOD PRESSURE;

OXIDATIVE STRESS;

ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATE; ALLOPURINOL; ANTIOXIDANT; OTERACIL; PROTEIN; TEMPOL; URIC ACID; AMINE OXIDE; SPIN LABEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BREATHING RATE; CELL FUNCTION; CONTROLLED STUDY; DISEASE DURATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME METABOLISM; HYPERTENSION; HYPERURICEMIA; KIDNEY BLOOD FLOW; KIDNEY CORTEX; KIDNEY DISEASE; KIDNEY INJURY; KIDNEY PLASMA FLOW; KIDNEY VASCULAR RESISTANCE; LIPID OXIDATION; LIPID PEROXIDATION; LONG TERM CARE; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RAT; RENAL PROTECTION; RENOVASCULAR HYPERTENSION; SYSTOLIC BLOOD PRESSURE; URIC ACID BLOOD LEVEL; VASCULAR RESISTANCE; VASOCONSTRICTION; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; KIDNEY; KIDNEY CIRCULATION; METABOLISM; PATHOLOGY; SPIN LABELS; SPRAGUE DAWLEY RAT; TIME FACTOR; VASCULARIZATION;

RATTUS;

ADENOSINE TRIPHOSPHATE; ALLOPURINOL; ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; HYPERTENSION; HYPERURICEMIA; KIDNEY; MALE; MITOCHONDRIA; OXIDATIVE STRESS; OXONIC ACID; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; SPIN LABELS; TIME FACTORS;

EID: 84928501261     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/535686     Document Type: Article

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