Oxidants induce a corticosteroid-insensitive phosphorylation of histone 3 at serine 10 in monocytes

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Marwick, John A ^a,b   Tudor, Corina ^a   Khorasani, Nadia ^a   Michaeloudes, Charalambos ^a   Bhavsar, Pankaj K ^a   Chung, Kian F ^a,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; BUDESONIDE; CORTICOSTEROID; DEXAMETHASONE; HISTONE H3; I KAPPA B KINASE BETA; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PREDNISOLONE; SECONDARY LYMPHOID TISSUE CHEMOKINE; SERINE; STRESS ACTIVATED PROTEIN KINASE 1; HISTONE; OXIDIZING AGENT;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GENE; GENE EXPRESSION; HUMAN; LUNG ALVEOLUS MACROPHAGE; MALE; MONOCYTE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TNFALPHA GENE; CHEMISTRY; DRUG EFFECTS; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; PHOSPHORYLATION;

ADRENAL CORTEX HORMONES; ADULT; FEMALE; HISTONES; HUMANS; MALE; MIDDLE AGED; MONOCYTES; OXIDANTS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SERINE;

EID: 84928501011     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124961     Document Type: Article

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