메뉴 건너뛰기




Volumn 28, Issue 4, 2015, Pages 810-816

Double-strand breaks from a radical commonly produced by DNA-damaging agents

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DOUBLE STRANDED DNA; PEROXY RADICAL; THIOL; FREE RADICAL; ISOTOPE;

EID: 84928473792     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/acs.chemrestox.5b00032     Document Type: Article
Times cited : (7)

References (47)
  • 1
    • 84865364870 scopus 로고    scopus 로고
    • Playing the end game: DNA double-strand break repair pathway choice
    • Chapman, J. R., Taylor, M. R. G., and Boulton, S. J. (2012) Playing the end game: DNA double-strand break repair pathway choice Mol. Cell 47, 497-510
    • (2012) Mol. Cell , vol.47 , pp. 497-510
    • Chapman, J.R.1    Taylor, M.R.G.2    Boulton, S.J.3
  • 2
    • 34249945536 scopus 로고    scopus 로고
    • DNA double-strand break repair: From mechanistic understanding to cancer treatment
    • Helleday, T., Lo, J., van Gent, D. C., and Engelward, B. P. (2007) DNA double-strand break repair: From mechanistic understanding to cancer treatment DNA Repair 6, 923-935
    • (2007) DNA Repair , vol.6 , pp. 923-935
    • Helleday, T.1    Lo, J.2    Van Gent, D.C.3    Engelward, B.P.4
  • 3
    • 78649449207 scopus 로고    scopus 로고
    • Coping with DNA double strand breaks
    • Hiom, K. (2010) Coping with DNA double strand breaks DNA Repair 9, 1256-1263
    • (2010) DNA Repair , vol.9 , pp. 1256-1263
    • Hiom, K.1
  • 4
    • 84887810170 scopus 로고    scopus 로고
    • DNA double strand cleavage via interstrand hydrogen atom abstraction
    • Taverna Porro, M. L. and Greenberg, M. M. (2013) DNA double strand cleavage via interstrand hydrogen atom abstraction J. Am. Chem. Soc. 135, 16368-16371
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 16368-16371
    • Taverna Porro, M.L.1    Greenberg, M.M.2
  • 5
    • 0027212615 scopus 로고
    • Some characteristics of DNA strand scission by macromolecular antitumor antibiotic C-1027 containing a novel enediyne chromophore
    • Sugiura, Y. and Matsumoto, T. (1993) Some characteristics of DNA strand scission by macromolecular antitumor antibiotic C-1027 containing a novel enediyne chromophore Biochemistry 32, 5548-5553
    • (1993) Biochemistry , vol.32 , pp. 5548-5553
    • Sugiura, Y.1    Matsumoto, T.2
  • 6
    • 0023820894 scopus 로고
    • Calicheamicin γ1: An antitumor antibiotic that cleaves double-stranded DNA site specifically
    • Zein, N., Sinha, A. M., McGahren, W. J., and Ellestad, G. A. (1988) Calicheamicin γ1: An antitumor antibiotic that cleaves double-stranded DNA site specifically Science 240, 1198-1201
    • (1988) Science , vol.240 , pp. 1198-1201
    • Zein, N.1    Sinha, A.M.2    McGahren, W.J.3    Ellestad, G.A.4
  • 7
    • 84901347004 scopus 로고    scopus 로고
    • The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA
    • Colis, L. C., Woo, C. M., Hegan, D. C., Li, Z., Glazer, P. M., and Herzon, S. B. (2014) The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA Nat. Chem. 6, 504-510
    • (2014) Nat. Chem. , vol.6 , pp. 504-510
    • Colis, L.C.1    Woo, C.M.2    Hegan, D.C.3    Li, Z.4    Glazer, P.M.5    Herzon, S.B.6
  • 8
    • 0024396338 scopus 로고
    • Structure of bleomycin-induced DNA double-strand breaks: Predominance of blunt ends and single-base 5 extensions
    • Povirk, L. F., Han, Y. H., and Steighner, R. J. (1989) Structure of bleomycin-induced DNA double-strand breaks: predominance of blunt ends and single-base 5 extensions Biochemistry 28, 5808-5814
    • (1989) Biochemistry , vol.28 , pp. 5808-5814
    • Povirk, L.F.1    Han, Y.H.2    Steighner, R.J.3
  • 9
    • 0025114681 scopus 로고
    • Bleomycin-induced DNA lesions at mutational hot spots: Implications for the mechanism of double-strand cleavage
    • Steighner, R. J. and Povirk, L. F. (1990) Bleomycin-induced DNA lesions at mutational hot spots: implications for the mechanism of double-strand cleavage Proc. Natl. Acad. Sci. U.S.A. 87, 8350-8354
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 8350-8354
    • Steighner, R.J.1    Povirk, L.F.2
  • 10
    • 0028923387 scopus 로고
    • Sequence-specific double-strand cleavage of DNA by Fe-bleomycin. 2. Mechanism and dynamics
    • Absalon, M. J., Wu, W., Kozarich, J. W., and Stubbe, J. (1995) Sequence-specific double-strand cleavage of DNA by Fe-bleomycin. 2. Mechanism and dynamics Biochemistry 34, 2076-2086
    • (1995) Biochemistry , vol.34 , pp. 2076-2086
    • Absalon, M.J.1    Wu, W.2    Kozarich, J.W.3    Stubbe, J.4
  • 11
    • 84896505257 scopus 로고    scopus 로고
    • Hairpin DNA sequences bound strongly by bleomycin exhibit enhanced double-strand cleavage
    • Roy, B. and Hecht, S. M. (2014) Hairpin DNA sequences bound strongly by bleomycin exhibit enhanced double-strand cleavage J. Am. Chem. Soc. 136, 4382-4393
    • (2014) J. Am. Chem. Soc. , vol.136 , pp. 4382-4393
    • Roy, B.1    Hecht, S.M.2
  • 12
    • 0025819978 scopus 로고
    • Coupled kinetic analysis of cleavage of DNA by esperiamicin and calicheamicin
    • Kishikawa, H., Jiang, Y.-P., Goodisman, J., and Dabrowiak, J. C. (1991) Coupled kinetic analysis of cleavage of DNA by esperiamicin and calicheamicin J. Am. Chem. Soc. 113, 5434-5440
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 5434-5440
    • Kishikawa, H.1    Jiang, Y.-P.2    Goodisman, J.3    Dabrowiak, J.C.4
  • 13
    • 0026652553 scopus 로고
    • Neocarzinostatin-mediated DNA damage in a model AGT·ACT site: Mechanistic studies of thiol-sensitive partitioning of C4 DNA damage products
    • Dedon, P. C., Jiang, Z. W., and Goldberg, I. H. (1992) Neocarzinostatin-mediated DNA damage in a model AGT·ACT site: mechanistic studies of thiol-sensitive partitioning of C4 DNA damage products Biochemistry 31, 1917-1927
    • (1992) Biochemistry , vol.31 , pp. 1917-1927
    • Dedon, P.C.1    Jiang, Z.W.2    Goldberg, I.H.3
  • 15
    • 0030937998 scopus 로고    scopus 로고
    • Kinetics of cleavage of intra- and extracellular simian virus 40 DNA with the enediyne anticancer drug C-1027
    • Kirk, C. A., Goodisman, J., Beerman, T. A., Gawron, L. S., and Dabrowiak, J. C. (1997) Kinetics of cleavage of intra- and extracellular simian virus 40 DNA with the enediyne anticancer drug C-1027 Biophys. Chem. 63, 201-209
    • (1997) Biophys. Chem. , vol.63 , pp. 201-209
    • Kirk, C.A.1    Goodisman, J.2    Beerman, T.A.3    Gawron, L.S.4    Dabrowiak, J.C.5
  • 16
    • 77950360354 scopus 로고    scopus 로고
    • Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
    • Eccles, L. J., Lomax, M. E., and ONeill, P. (2010) Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage Nucleic Acids Res. 38, 1123-1134
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1123-1134
    • Eccles, L.J.1    Lomax, M.E.2    Oneill, P.3
  • 17
    • 64549162745 scopus 로고    scopus 로고
    • The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells
    • Kozmin, S. G., Sedletska, Y., Reynaud-Angelin, A., Gasparutto, D., and Sage, E. (2009) The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells Nucleic Acids Res. 37, 1767-1777
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1767-1777
    • Kozmin, S.G.1    Sedletska, Y.2    Reynaud-Angelin, A.3    Gasparutto, D.4    Sage, E.5
  • 18
    • 84862114377 scopus 로고    scopus 로고
    • Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone
    • Zhou, C. and Greenberg, M. M. (2012) Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone J. Am. Chem. Soc. 134, 8090-8093
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 8090-8093
    • Zhou, C.1    Greenberg, M.M.2
  • 19
    • 84867366918 scopus 로고    scopus 로고
    • Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles
    • Zhou, C., Sczepanski, J. T., and Greenberg, M. M. (2012) Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles J. Am. Chem. Soc. 134, 16734-16741
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 16734-16741
    • Zhou, C.1    Sczepanski, J.T.2    Greenberg, M.M.3
  • 20
    • 78651077907 scopus 로고    scopus 로고
    • Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle
    • Sczepanski, J. T., Wong, R. S., McKnight, J. N., Bowman, G. D., and Greenberg, M. M. (2010) Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle Proc. Natl. Acad. Sci. U.S.A. 107, 22475-22480
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 22475-22480
    • Sczepanski, J.T.1    Wong, R.S.2    McKnight, J.N.3    Bowman, G.D.4    Greenberg, M.M.5
  • 21
    • 84860777961 scopus 로고    scopus 로고
    • Hybrids of amino acids and acetylenic DNA-photocleavers: Optimising efficiency and selectivity for cancer phototherapy
    • Breiner, B., Kaya, K., Roy, S., Yang, W.-Y., and Alabugin, I. V. (2012) Hybrids of amino acids and acetylenic DNA-photocleavers: optimising efficiency and selectivity for cancer phototherapy Org. Biomol. Chem. 10, 3974-3987
    • (2012) Org. Biomol. Chem. , vol.10 , pp. 3974-3987
    • Breiner, B.1    Kaya, K.2    Roy, S.3    Yang, W.-Y.4    Alabugin, I.V.5
  • 23
    • 0032765170 scopus 로고    scopus 로고
    • Formation of single- and double-strand breaks of PBR322 plasmid irradiated in the presence of scavengers
    • Shao, C., Saito, M., and Yu, Z. (1999) Formation of single- and double-strand breaks of PBR322 plasmid irradiated in the presence of scavengers Radiat. Environ. Biophys. 38, 105-109
    • (1999) Radiat. Environ. Biophys. , vol.38 , pp. 105-109
    • Shao, C.1    Saito, M.2    Yu, Z.3
  • 24
    • 0023636148 scopus 로고
    • Single- and double-strand break formation in DNA irradiated in aqueous solution: Dependence on dose and OH radical scavenger concentration
    • Siddiqi, M. A. and Bothe, E. (1987) Single- and double-strand break formation in DNA irradiated in aqueous solution: Dependence on dose and OH radical scavenger concentration Radiat. Res. 112, 449-463
    • (1987) Radiat. Res. , vol.112 , pp. 449-463
    • Siddiqi, M.A.1    Bothe, E.2
  • 25
    • 0025034286 scopus 로고
    • DNA double-strand breaks: Their repair and relationship to cell killing in yeast
    • Frankenberg-Schwager, M. and Frankenberg, D. (1990) DNA double-strand breaks: their repair and relationship to cell killing in yeast Int. J. Radiat. Biol. 58, 569-575
    • (1990) Int. J. Radiat. Biol. , vol.58 , pp. 569-575
    • Frankenberg-Schwager, M.1    Frankenberg, D.2
  • 28
    • 0030929539 scopus 로고    scopus 로고
    • Spectroscopic evidence for a radical cation as intermediate in a model reaction of the 4-DNA radical strand cleavage
    • Gugger, A., Batra, R., Rzadek, P., Rist, G., and Giese, B. (1997) Spectroscopic evidence for a radical cation as intermediate in a model reaction of the 4-DNA radical strand cleavage J. Am. Chem. Soc. 119, 8740-8741
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 8740-8741
    • Gugger, A.1    Batra, R.2    Rzadek, P.3    Rist, G.4    Giese, B.5
  • 29
    • 0032486755 scopus 로고    scopus 로고
    • Spontaneous cleavage of 4-DNA radicals under aerobic conditions: Apparent discrepancy between trapping rates and cleavage products
    • Dussy, A., Meggers, E., and Giese, B. (1998) Spontaneous cleavage of 4-DNA radicals under aerobic conditions: apparent discrepancy between trapping rates and cleavage products J. Am. Chem. Soc. 120, 7399-7403
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 7399-7403
    • Dussy, A.1    Meggers, E.2    Giese, B.3
  • 30
    • 0034602977 scopus 로고    scopus 로고
    • Electron transfer in DNA from guanine and 8-oxoguanine to a radical cation of the carbohydrate backbone
    • Meggers, E., Dussy, A., Schäfer, T., and Giese, B. (2000) Electron transfer in DNA from guanine and 8-oxoguanine to a radical cation of the carbohydrate backbone Chem.-Eur. J. 6, 485-492
    • (2000) Chem.-Eur. J. , vol.6 , pp. 485-492
    • Meggers, E.1    Dussy, A.2    Schäfer, T.3    Giese, B.4
  • 32
    • 0026628980 scopus 로고
    • New insight into the mechanism of base propenal formation during bleomycin-mediated DNA degradation
    • McGall, G. H., Rabow, L. E., Ashley, G. W., Wu, S. H., Kozarich, J. W., and Stubbe, J. (1992) New insight into the mechanism of base propenal formation during bleomycin-mediated DNA degradation J. Am. Chem. Soc. 114, 4958-4967
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 4958-4967
    • McGall, G.H.1    Rabow, L.E.2    Ashley, G.W.3    Wu, S.H.4    Kozarich, J.W.5    Stubbe, J.6
  • 33
    • 0025035579 scopus 로고
    • Identification of the source of oxygen in the alkaline-labile product accompanying cytosine release during bleomycin-mediated oxidative degradation of d(CGCGCG)
    • Rabow, L. E., McGall, G. H., Stubbe, J., and Kozarich, J. W. (1990) Identification of the source of oxygen in the alkaline-labile product accompanying cytosine release during bleomycin-mediated oxidative degradation of d(CGCGCG) J. Am. Chem. Soc. 112, 3203-3208
    • (1990) J. Am. Chem. Soc. , vol.112 , pp. 3203-3208
    • Rabow, L.E.1    McGall, G.H.2    Stubbe, J.3    Kozarich, J.W.4
  • 36
    • 0025774650 scopus 로고
    • Isotope effects on the sequence-specific cleavage of DNA by neocarzinostatin: Kinetic partitioning between 4- and 5-hydrogen abstraction at unique thymidine sites
    • Frank, B. L., Worth, L., Jr., Christner, D. F., Kozarich, J. W., Stubbe, J., Kappen, L. S., and Goldberg, I. H. (1991) Isotope effects on the sequence-specific cleavage of DNA by neocarzinostatin: kinetic partitioning between 4- and 5-hydrogen abstraction at unique thymidine sites J. Am. Chem. Soc. 113, 2271-2275
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 2271-2275
    • Frank, B.L.1    Worth, Jr.L.2    Christner, D.F.3    Kozarich, J.W.4    Stubbe, J.5    Kappen, L.S.6    Goldberg, I.H.7
  • 38
    • 0032544035 scopus 로고    scopus 로고
    • DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone
    • Balasubramanian, B., Pogozelski, W. K., and Tullius, T. D. (1998) DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone Proc. Natl. Acad. Sci. U.S.A. 95, 9738-9743
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 9738-9743
    • Balasubramanian, B.1    Pogozelski, W.K.2    Tullius, T.D.3
  • 40
    • 0029987285 scopus 로고    scopus 로고
    • A novel mechanism for the formation of direct strand breaks upon anaerobic photolysis of duplex DNA containing 5-bromodeoxyuridine
    • Cook, G. P. and Greenberg, M. M. (1996) A novel mechanism for the formation of direct strand breaks upon anaerobic photolysis of duplex DNA containing 5-bromodeoxyuridine J. Am. Chem. Soc. 118, 10025-10030
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 10025-10030
    • Cook, G.P.1    Greenberg, M.M.2
  • 41
    • 84863985641 scopus 로고    scopus 로고
    • DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases
    • San Pedro, J. M. N., Beerman, T. A., and Greenberg, M. M. (2012) DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases Bioorg. Med. Chem. 20, 4744-4750
    • (2012) Bioorg. Med. Chem. , vol.20 , pp. 4744-4750
    • San Pedro, J.M.N.1    Beerman, T.A.2    Greenberg, M.M.3
  • 42
    • 0242267569 scopus 로고    scopus 로고
    • Tandem lesions are the major products resulting from a pyrimidine nucleobase radical
    • Carter, K. N. and Greenberg, M. M. (2003) Tandem lesions are the major products resulting from a pyrimidine nucleobase radical J. Am. Chem. Soc. 125, 13376-13378
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 13376-13378
    • Carter, K.N.1    Greenberg, M.M.2
  • 44
    • 33748322763 scopus 로고
    • The elucidation of peroxyl radical reactions in aqueous solution with the help of radiation-chemical methods
    • von Sonntag, C. and Schuchmann, H.-P. (1991) The elucidation of peroxyl radical reactions in aqueous solution with the help of radiation-chemical methods Angew. Chem., Int. Ed. Engl. 30, 1229-1253
    • (1991) Angew. Chem., Int. Ed. Engl. , vol.30 , pp. 1229-1253
    • Von Sonntag, C.1    Schuchmann, H.-P.2
  • 45
    • 0030980116 scopus 로고    scopus 로고
    • Time-resolved EPR studies on the reaction rates of peroxyl radicals of poly(acrylic acid) and of calf thymus DNA with glutathione. Re-examination of a rate constant for DNA
    • Hildenbrand, K. and Schulte-Frohlinde, D. (1997) Time-resolved EPR studies on the reaction rates of peroxyl radicals of poly(acrylic acid) and of calf thymus DNA with glutathione. Re-examination of a rate constant for DNA Int. J. Radiat. Biol. 71, 377-385
    • (1997) Int. J. Radiat. Biol. , vol.71 , pp. 377-385
    • Hildenbrand, K.1    Schulte-Frohlinde, D.2
  • 46
    • 77349088243 scopus 로고    scopus 로고
    • Activation of DNA carbon, hydrogen bonds by metal complexes
    • Pitié, M. and Pratviel, G. (2010) Activation of DNA carbon, hydrogen bonds by metal complexes Chem. Rev. 110, 1018-1059
    • (2010) Chem. Rev. , vol.110 , pp. 1018-1059
    • Pitié, M.1    Pratviel, G.2
  • 47
    • 34247153489 scopus 로고    scopus 로고
    • Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical
    • Hong, I. S., Carter, K. N., Sato, K., and Greenberg, M. M. (2007) Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical J. Am. Chem. Soc. 129, 4089-4098
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 4089-4098
    • Hong, I.S.1    Carter, K.N.2    Sato, K.3    Greenberg, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.