메뉴 건너뛰기




Volumn 120, Issue 30, 1998, Pages 7399-7403

Spontaneous cleavage of 4'-DNA radicals under aerobic conditions: Apparent discrepancy between trapping rates and cleavage products

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; RADICAL; SINGLE STRANDED DNA;

EID: 0032486755     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja980036f     Document Type: Article
Times cited : (43)

References (23)
  • 1
    • 33748719327 scopus 로고
    • For reviews see: (a) Stubbe, J.; Kozarich, J. W. Chem. Rev. 1987, 87, 1107. (b) Pratviel, G.; Bernadou, J.; Meunier, B. Angew. Chem., Int. Ed. Engl. 1995, 34, 746. (c) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18. 1033.
    • (1987) Chem. Rev. , vol.87 , pp. 1107
    • Stubbe, J.1    Kozarich, J.W.2
  • 2
    • 0029103994 scopus 로고
    • For reviews see: (a) Stubbe, J.; Kozarich, J. W. Chem. Rev. 1987, 87, 1107. (b) Pratviel, G.; Bernadou, J.; Meunier, B. Angew. Chem., Int. Ed. Engl. 1995, 34, 746. (c) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18. 1033.
    • (1995) Angew. Chem., Int. Ed. Engl. , vol.34 , pp. 746
    • Pratviel, G.1    Bernadou, J.2    Meunier, B.3
  • 3
    • 0028927261 scopus 로고
    • For reviews see: (a) Stubbe, J.; Kozarich, J. W. Chem. Rev. 1987, 87, 1107. (b) Pratviel, G.; Bernadou, J.; Meunier, B. Angew. Chem., Int. Ed. Engl. 1995, 34, 746. (c) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18. 1033.
    • (1995) Free Radical Biol. Med. , vol.18 , pp. 1033
    • Breen, A.P.1    Murphy, J.A.2
  • 12
    • 0023937127 scopus 로고
    • Because of the repulsion between the negative charges, GSH reacts about 5 times slower than the diethyl ester of GSH. See also: Zheng, S.; Newton, G. L.; Gonick, G.; Fancy, R. C.; Ward, J. F. Radiat. Res. 1988, 114, 11.
    • (1988) Radiat. Res. , vol.114 , pp. 11
    • Zheng, S.1    Newton, G.L.2    Gonick, G.3    Fancy, R.C.4    Ward, J.F.5
  • 13
    • 3543006704 scopus 로고    scopus 로고
    • note
    • 2 and GSH. Under these conditions H abstraction from oligonucleotides with subsequent formation of strand cleavage or isomerization products could not be observed by HPLC, although the ketone was consumed within 6 min of irradiation (320 nm cutoff filter).
  • 22
    • 0002178842 scopus 로고    scopus 로고
    • Alfassi, Z., Ed.; J. Wiley: New York
    • For a comparison with other peroxyl radicals, see: von Sonntag, C.; Schuchmann, H.-P. In Peroxyl Radicals; Alfassi, Z., Ed.; J. Wiley: New York, 1997; p 173.
    • (1997) Peroxyl Radicals , pp. 173
    • Von Sonntag, C.1    Schuchmann, H.-P.2
  • 23
    • 3542995232 scopus 로고    scopus 로고
    • note
    • 2 slower than single-stranded 4'-DNA peroxyl radicals.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.