메뉴 건너뛰기




Volumn 6, Issue 10, 2015, Pages 7804-7814

AP-1-mediated chromatin looping regulates ZEB2 transcription: New insights into TNFα-induced epithelial-mesenchymal transition in triple-negative breast cancer

Author keywords

AP 1; Epithelial mesenchymal transition; TNF ; Triple negative breast cancer; ZEB2

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ZEB2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHROMATIN; HOMEODOMAIN PROTEIN; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; TUMOR NECROSIS FACTOR; ZEB2 PROTEIN, HUMAN;

EID: 84928405613     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3158     Document Type: Article
Times cited : (46)

References (43)
  • 1
    • 78650032040 scopus 로고    scopus 로고
    • Triple-negative breast cancer: a short review
    • Elias AD. Triple-negative breast cancer: a short review. Am J Clin Oncol. 2010; 33:637-645.
    • (2010) Am J Clin Oncol , vol.33 , pp. 637-645
    • Elias, A.D.1
  • 2
    • 79151476662 scopus 로고    scopus 로고
    • Triple negative breast cancer: unmet medical needs
    • Pal SK, Childs BH, Pegram M. Triple negative breast cancer: unmet medical needs. Breast Cancer Res Treat. 2011; 125:627-636.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 627-636
    • Pal, S.K.1    Childs, B.H.2    Pegram, M.3
  • 3
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E, Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol. 2002; 4:E131-136.
    • (2002) Nat Cell Biol , vol.4 , pp. E131-E136
    • Shaulian, E.1    Karin, M.2
  • 4
    • 77949916262 scopus 로고    scopus 로고
    • AP-1-The Jun proteins: oncogenes or tumor suppressors in disguise?
    • Shaulian E. AP-1-The Jun proteins: oncogenes or tumor suppressors in disguise? Cell Signal. 2010; 22:894-899.
    • (2010) Cell Signal , vol.22 , pp. 894-899
    • Shaulian, E.1
  • 5
    • 77957969757 scopus 로고    scopus 로고
    • The dual role of tumor necrosis factor (TNF) in cancer biology
    • Bertazza L, Mocellin S. The dual role of tumor necrosis factor (TNF) in cancer biology. Curr Med Chem. 2010; 17:3337-3352.
    • (2010) Curr Med Chem , vol.17 , pp. 3337-3352
    • Bertazza, L.1    Mocellin, S.2
  • 7
    • 33748291392 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha and its receptors in human benign breast lesions and tumors (in situ and infiltrative)
    • Garcia-Tunon I, Ricote M, Ruiz A, Fraile B, Paniagua R, Royuela M. Role of tumor necrosis factor-alpha and its receptors in human benign breast lesions and tumors (in situ and infiltrative). Cancer Sci. 2006; 97:1044-1049.
    • (2006) Cancer Sci , vol.97 , pp. 1044-1049
    • Garcia-Tunon, I.1    Ricote, M.2    Ruiz, A.3    Fraile, B.4    Paniagua, R.5    Royuela, M.6
  • 9
    • 70349488509 scopus 로고    scopus 로고
    • Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice
    • Warren MA, Shoemaker SF, Shealy DJ, Bshar W, Ip MM. Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice. Mol Cancer Ther. 2009; 8:2655-2663.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2655-2663
    • Warren, M.A.1    Shoemaker, S.F.2    Shealy, D.J.3    Bshar, W.4    Ip, M.M.5
  • 10
    • 84872176009 scopus 로고    scopus 로고
    • TNF-alpha gene knockout in triple negative breast cancer cell line induces apoptosis
    • Pileczki V, Braicu C, Gherman CD, Berindan-Neagoe I. TNF-alpha gene knockout in triple negative breast cancer cell line induces apoptosis. Int J Mol Sci. 2012; 14:411-420.
    • (2012) Int J Mol Sci , vol.14 , pp. 411-420
    • Pileczki, V.1    Braicu, C.2    Gherman, C.D.3    Berindan-Neagoe, I.4
  • 11
    • 67649417877 scopus 로고    scopus 로고
    • Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB
    • Katoh M. Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. Int J Oncol. 2009; 34:1737-1742.
    • (2009) Int J Oncol , vol.34 , pp. 1737-1742
    • Katoh, M.1
  • 12
    • 84863236117 scopus 로고    scopus 로고
    • ZEB2 upregulates integrin alpha5 expression through cooperation with Sp1 to induce invasion during epithelial-mesenchymal transition of human cancer cells
    • Nam EH, Lee Y, Park YK, Lee JW, Kim S. ZEB2 upregulates integrin alpha5 expression through cooperation with Sp1 to induce invasion during epithelial-mesenchymal transition of human cancer cells. Carcinogenesis. 2012; 33:563-571.
    • (2012) Carcinogenesis , vol.33 , pp. 563-571
    • Nam, E.H.1    Lee, Y.2    Park, Y.K.3    Lee, J.W.4    Kim, S.5
  • 13
    • 84904255200 scopus 로고    scopus 로고
    • Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer
    • Zhao C, Qiao Y, Jonsson P, Wang J, Xu L, Rouhi P, Sinha I, Cao Y, Williams C, Dahlman-Wright K. Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer. Cancer Res. 2014; 74:3983-3994.
    • (2014) Cancer Res , vol.74 , pp. 3983-3994
    • Zhao, C.1    Qiao, Y.2    Jonsson, P.3    Wang, J.4    Xu, L.5    Rouhi, P.6    Sinha, I.7    Cao, Y.8    Williams, C.9    Dahlman-Wright, K.10
  • 15
    • 84872446709 scopus 로고    scopus 로고
    • Methods for identifying higherorder chromatin structure
    • Sajan SA, Hawkins RD. Methods for identifying higherorder chromatin structure. Annu Rev Genomics Hum Genet. 2012; 13:59-82.
    • (2012) Annu Rev Genomics Hum Genet , vol.13 , pp. 59-82
    • Sajan, S.A.1    Hawkins, R.D.2
  • 16
    • 84865800494 scopus 로고    scopus 로고
    • The long-range interaction landscape of gene promoters
    • Sanyal A, Lajoie BR, Jain G, Dekker J. The long-range interaction landscape of gene promoters. Nature. 2012; 489:109-113.
    • (2012) Nature , vol.489 , pp. 109-113
    • Sanyal, A.1    Lajoie, B.R.2    Jain, G.3    Dekker, J.4
  • 17
    • 33645302628 scopus 로고    scopus 로고
    • The epithelialmesenchymal transition: new insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelialmesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006; 172:973-981.
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 18
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell. 2009; 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 19
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell. 2008; 14:818-829.
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 20
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer. 2009; 9:265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 21
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol. 2006; 7:131-142.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 22
    • 58149316623 scopus 로고    scopus 로고
    • Snail and slug promote epithelial-mesenchymal transition through beta-catenin-Tcell factor-4-dependent expression of transforming growth factor-beta3
    • Medici D, Hay ED, Olsen BR. Snail and slug promote epithelial-mesenchymal transition through beta-catenin-Tcell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell. 2008; 19:4875-4887.
    • (2008) Mol Biol Cell , vol.19 , pp. 4875-4887
    • Medici, D.1    Hay, E.D.2    Olsen, B.R.3
  • 25
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009; 9:361-371.
    • (2009) Nat Rev Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 26
    • 84893829084 scopus 로고    scopus 로고
    • Progression of luminal breast tumors is promoted by menage a trois between the inflammatory cytokine TNFalpha and the hormonal and growth-supporting arms of the tumor microenvironment
    • 720536
    • Weitzenfeld P, Meron N, Leibovich-Rivkin T, Meshel T, Ben-Baruch A. Progression of luminal breast tumors is promoted by menage a trois between the inflammatory cytokine TNFalpha and the hormonal and growth-supporting arms of the tumor microenvironment. Mediators Inflamm. 2013; 2013:720536.
    • (2013) Mediators Inflamm , vol.2013
    • Weitzenfeld, P.1    Meron, N.2    Leibovich-Rivkin, T.3    Meshel, T.4    Ben-Baruch, A.5
  • 29
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014; 15:178-196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 30
    • 84884938341 scopus 로고    scopus 로고
    • Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells
    • Liu J, Hu G, Chen D, Gong AY, Soori GS, Dobleman TJ, Chen XM. Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells. Oncogenesis. 2013; 2:e73.
    • (2013) Oncogenesis , vol.2
    • Liu, J.1    Hu, G.2    Chen, D.3    Gong, A.Y.4    Soori, G.S.5    Dobleman, T.J.6    Chen, X.M.7
  • 32
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell. 2009; 15:416-428.
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 34
    • 84903579683 scopus 로고    scopus 로고
    • Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer
    • Jacob S, Nayak S, Fernandes G, Barai RS, Menon S, Chaudhari UK, Kholkute SD, Sachdeva G. Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer. Endocr Relat Cancer. 2014; 21:473-486.
    • (2014) Endocr Relat Cancer , vol.21 , pp. 473-486
    • Jacob, S.1    Nayak, S.2    Fernandes, G.3    Barai, R.S.4    Menon, S.5    Chaudhari, U.K.6    Kholkute, S.D.7    Sachdeva, G.8
  • 36
    • 33344471142 scopus 로고    scopus 로고
    • Regulation of gene expression by alternative untranslated regions
    • Hughes TA. Regulation of gene expression by alternative untranslated regions. Trends Genet. 2006; 22:119-122.
    • (2006) Trends Genet , vol.22 , pp. 119-122
    • Hughes, T.A.1
  • 37
    • 59349086115 scopus 로고    scopus 로고
    • Chromatin loops in gene regulation
    • Kadauke S, Blobel GA. Chromatin loops in gene regulation. Biochim Biophys Acta. 2009; 1789:17-25.
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 17-25
    • Kadauke, S.1    Blobel, G.A.2
  • 38
    • 79959469938 scopus 로고    scopus 로고
    • The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR
    • Gong F, Sun L, Wang Z, Shi J, Li W, Wang S, Han X, Sun Y. The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR. Nucleic Acids Res. 2011; 39:4640-4652.
    • (2011) Nucleic Acids Res , vol.39 , pp. 4640-4652
    • Gong, F.1    Sun, L.2    Wang, Z.3    Shi, J.4    Li, W.5    Wang, S.6    Han, X.7    Sun, Y.8
  • 39
    • 34547436788 scopus 로고    scopus 로고
    • Cell-type-specific expression of the human CD68 gene is associated with changes in Pol II phosphorylation and short-range intrachromosomal gene looping
    • O'Reilly D, Greaves DR. Cell-type-specific expression of the human CD68 gene is associated with changes in Pol II phosphorylation and short-range intrachromosomal gene looping. Genomics. 2007; 90:407-415.
    • (2007) Genomics , vol.90 , pp. 407-415
    • O'Reilly, D.1    Greaves, D.R.2
  • 40
    • 77952763143 scopus 로고    scopus 로고
    • Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells
    • Deshane J, Kim J, Bolisetty S, Hock TD, Hill-Kapturczak N, Agarwal A. Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells. J Biol Chem. 2010; 285:16476-16486.
    • (2010) J Biol Chem , vol.285 , pp. 16476-16486
    • Deshane, J.1    Kim, J.2    Bolisetty, S.3    Hock, T.D.4    Hill-Kapturczak, N.5    Agarwal, A.6
  • 41
    • 43749099640 scopus 로고    scopus 로고
    • Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene
    • Babu DA, Chakrabarti SK, Garmey JC, Mirmira RG. Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem. 2008; 283:8164-8172.
    • (2008) J Biol Chem , vol.283 , pp. 8164-8172
    • Babu, D.A.1    Chakrabarti, S.K.2    Garmey, J.C.3    Mirmira, R.G.4
  • 43
    • 67349121053 scopus 로고    scopus 로고
    • c-Myc induces changes in higher order rDNA structure on stimulation of quiescent cells
    • Shiue CN, Berkson RG, Wright AP. c-Myc induces changes in higher order rDNA structure on stimulation of quiescent cells. Oncogene. 2009; 28:1833-1842.
    • (2009) Oncogene , vol.28 , pp. 1833-1842
    • Shiue, C.N.1    Berkson, R.G.2    Wright, A.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.