Evaluation of an optimized protocol using human peripheral blood monocyte derived dendritic cells for the in vitro detection of sensitizers: Results of a ring study in five laboratories

Toxicology in Vitro

Volumn 29, Issue 5, 2015, Pages 976-986

  Reuter, Hendrik ^a   Gerlach, Silke ^a   Spieker, Jochem ^a   Ryan, Cindy ^b   Bauch, Caroline ^d   Mangez, Claire ^e   Winkler, Petra ^e   Landsiedel, Robert ^d   Templier, Marie ^c   Mignot, Aurelien ^c   Gerberick, Frank ^b   Wenck, Horst ^a   Aeby, Pierre ^f   Schepky, Andreas ^a  

^a BEIERSDORF AG   (Germany)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^d BASF SE   (Germany)

^e JOHNSON AND JOHNSON   (United States)

^f Independent Consultant   (Switzerland)

Author keywords

Human dendritic cells; In vitro test system; Peripheral blood monocyte derived dendritic cells; Ring study; Skin sensitization

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 4 HYDROXYBENZOIC ACID; ALPHA HEXYLCINNAMALDEHYDE; CD86 ANTIGEN; CHEMICAL COMPOUND; DODECYL SULFATE SODIUM; EUGENOL; HYDROXYCITRONELLAL; NICKEL SULFATE; UNCLASSIFIED DRUG; ALLERGEN;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LABORATORY TEST; LOCAL LYMPH NODE ASSAY; MONOCYTE; PROCESS OPTIMIZATION; RELIABILITY; REPRODUCIBILITY; SKIN SENSITIZATION; ANIMAL TESTING ALTERNATIVE; CYTOLOGY; EVALUATION STUDY; IMMUNOLOGY; LABORATORY; SKIN ALLERGY;

ANIMALIA;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; DENDRITIC CELLS; DERMATITIS, ALLERGIC CONTACT; HUMANS; LABORATORIES; MONOCYTES; REPRODUCIBILITY OF RESULTS;

EID: 84928394885     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.03.021     Document Type: Article

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