Bayesian network ensemble as a multivariate strategy to predict radiation pneumonitis risk

Medical Physics

Volumn 42, Issue 5, 2015, Pages 2421-2430

  Lee, Sangkyu ^a   Ybarra, Norma ^a   Jeyaseelan, Krishinima ^a   Seuntjens, Jan ^a   El Naqa, Issam ^a   Faria, Sergio ^b   Kopek, Neil ^b   Brisebois, Pascale ^b   Bradley, Jeffrey D ^c   Robinson, Clifford ^c  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bayesian network; biomarker; ensemble learning; NTCP; radiation pneumonitis

Indexed keywords

ASSOCIATION REACTIONS; BARIUM COMPOUNDS; BIOMARKERS; CURVE FITTING; DECISION TREES; DIRECTED GRAPHS; DISEASES; FORECASTING; MARKOV PROCESSES; MONTE CARLO METHODS; RADIOTHERAPY;

ANGIOTENSIN-CONVERTING ENZYME; BAYESIA N NETWORKS; COVARIATES; DOSE-VOLUME; ENSEMBLE LEARNING; HIGHLY-CORRELATED; NETWORK ENSEMBLE; NTCP; PROBABILISTIC FRAMEWORK; RADIATION PNEUMONITIS;

BAYESIAN NETWORKS;

ALPHA 2 MACROGLOBULIN; BIOLOGICAL MARKER; DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR; IL6 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BAYESIAN LEARNING; BLOOD SAMPLING; BOOTSTRAPPING; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; COMPUTER ASSISTED RADIOTHERAPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; KARNOFSKY PERFORMANCE STATUS; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MONTE CARLO METHOD; MULTIVARIATE ANALYSIS; NETWORK LEARNING; PREDICTION; PROBABILITY; RADIATION HAZARD; RADIATION PNEUMONIA; RADIOSENSITIVITY; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR; VOLUMETRY; ADVERSE EFFECTS; AREA UNDER THE CURVE; BAYES THEOREM; BLOOD; CARCINOMA, NON-SMALL-CELL LUNG; COHORT ANALYSIS; CONFORMAL RADIOTHERAPY; EVALUATION STUDY; HEART; MACHINE LEARNING; MARKOV CHAIN; METABOLISM; RADIATION PNEUMONITIS; RADIATION RESPONSE; RADIOTHERAPY DOSAGE; STATISTICAL MODEL;

ALPHA-MACROGLOBULINS; AREA UNDER CURVE; BAYES THEOREM; BIOMARKERS; CARCINOMA, NON-SMALL-CELL LUNG; COHORT STUDIES; HEART; HUMANS; INTERLEUKIN-6; LOGISTIC MODELS; MACHINE LEARNING; MARKOV CHAINS; MONTE CARLO METHOD; MULTIVARIATE ANALYSIS; PEPTIDYL-DIPEPTIDASE A; RADIATION PNEUMONITIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; ROC CURVE; TRANSFORMING GROWTH FACTORS;

EID: 84928387960     PISSN: 00942405     EISSN: 24734209     Source Type: Journal    
DOI: 10.1118/1.4915284     Document Type: Article

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45. See supplementary material at http://dx.doi.org/10.1118/1.4915284 E-MPHYA6-42-050504 for materials on the machine learning concepts pertaining to the presented methodology.