Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Journal of Proteomics

Volumn 118, Issue , 2015, Pages 81-94

  Lambert, Jean Philippe ^a   Tucholska, Monika ^a   Go, Christopher ^a,b   Knight, James D R ^a   Gingras, Anne Claude ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Affinity purification coupled to mass spectrometry; BioID; Chromatin; Protein protein interactions; Proximity biotinylation; Systems biology

Indexed keywords

BIOTIN; BIOTIN PROTEIN LIGASE; CHROMATIN ASSOCIATED PROTEIN; HISTONE; LIGASE; MEDIATOR COMPLEX; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; BIRA PROTEIN, E COLI; CHROMATIN; ESCHERICHIA COLI PROTEIN; MED4 PROTEIN, HUMAN; REPRESSOR PROTEIN;

AFFINITY PURIFICATION COUPLED TO MASS SPECTROMETRY; ARTICLE; BIOTINYLATION; CENTROSOME; CONTROLLED STUDY; IMMUNOFLUORESCENCE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; CHROMATIN; ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM;

CARBON-NITROGEN LIGASES; CHROMATIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; MEDIATOR COMPLEX; REPRESSOR PROTEINS;

EID: 84928345855     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2014.09.011     Document Type: Article

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