메뉴 건너뛰기




Volumn 40, Issue 1, 2014, Pages 36-42

Role of NHE1 in the cellular dysfunction of acute metabolic acidosis

Author keywords

Cardiac function; Ketoacidosis; Lactic acidosis; Metabolic acidosis; NHE1

Indexed keywords

CALCIUM; CYTOKINE; SODIUM; SODIUM PROTON EXCHANGE PROTEIN 1; CATION TRANSPORT PROTEIN; SLC9A1 PROTEIN, HUMAN; SLC9A1 PROTEIN, RAT; SODIUM PROTON EXCHANGE PROTEIN;

EID: 84928327782     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000364783     Document Type: Review
Times cited : (30)

References (40)
  • 1
    • 0019554835 scopus 로고
    • Intracellular pH
    • Roos A, Boron WP: Intracellular pH. Physiol Rev 1981; 61: 296-434
    • (1981) Physiol Rev , vol.61 , pp. 296-434
    • Roos, A.1    Boron, W.P.2
  • 2
    • 77951877242 scopus 로고    scopus 로고
    • Metabolic acidosis: Pathophysiology, diagnosis and management
    • Kraut JA, Madias NE: Metabolic acidosis: Pathophysiology, diagnosis and management. Nat Rev Nephrol 2010; 6: 274-285
    • (2010) Nat Rev Nephrol , vol.6 , pp. 274-285
    • Kraut, J.A.1    Madias, N.E.2
  • 3
    • 84867000481 scopus 로고    scopus 로고
    • Treatment of acute metabolic acidosis
    • Kraut JA, Madias NE: Treatment of acute metabolic acidosis. Nat Rev Nephrol 2012; 8: 589-601
    • (2012) Nat Rev Nephrol , vol.8 , pp. 589-601
    • Kraut, J.A.1    Madias, N.E.2
  • 4
    • 0029005161 scopus 로고
    • Cardiovascular responses to graded doses of 3 catecholamines during lactic and hydrochloric acidosis in dogs
    • Huang YG, Wong KC, Yip WH, McJames SW, Pace NL: Cardiovascular responses to graded doses of 3 catecholamines during lactic and hydrochloric acidosis in dogs. Br J Anaesth 1995; 74: 583-590
    • (1995) Br J Anaesth , vol.74 , pp. 583-590
    • Huang, Y.G.1    Wong, K.C.2    Yip, W.H.3    McJames, S.W.4    Pace, N.L.5
  • 5
    • 77953133213 scopus 로고    scopus 로고
    • Acid-sensing ion channels in acidosis-induced injury of human brain neurons
    • Li MH, Inoue K, Branigan D, et al: Acid-sensing ion channels in acidosis-induced injury of human brain neurons. J Cereb Blood Flow Metab 2010; 30: 1247-1260
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1247-1260
    • Li, M.H.1    Inoue, K.2    Branigan, D.3
  • 7
    • 0347784957 scopus 로고    scopus 로고
    • Use of base in the treatment of severe acidemic states
    • Kraut JA, Kurtz I: Use of base in the treatment of severe acidemic states. Am J Kidney Dis 2001; 38: 703-727
    • (2001) Am J Kidney Dis , vol.38 , pp. 703-727
    • Kraut, J.A.1    Kurtz, I.2
  • 8
    • 14344265433 scopus 로고    scopus 로고
    • Cardiovascular effects of Na + /H + exchanger inhibition with BIIB513 following hypovolemic circulatory shock
    • Wu DM, Bassuk J, Arias J, Doods H, Adams JA: Cardiovascular effects of Na + /H + exchanger inhibition with BIIB513 following hypovolemic circulatory shock. Shock 2005; 23: 269-274
    • (2005) Shock , vol.23 , pp. 269-274
    • Wu, D.M.1    Bassuk, J.2    Arias, J.3    Doods, H.4    Adams, J.A.5
  • 9
    • 79954594092 scopus 로고    scopus 로고
    • Potential role of NHE1(sodium-hydrogen exchanger 1) in the cellular dysfunction of lactic acidosis: Implications for treatment
    • Wu DM, Kraut JA: Potential role of NHE1(sodium-hydrogen exchanger 1) in the cellular dysfunction of lactic acidosis: Implications for treatment. Am J Kidney Dis 2011; 57: 781-787
    • (2011) Am J Kidney Dis , vol.57 , pp. 781-787
    • Wu, D.M.1    Kraut, J.A.2
  • 10
    • 84880332023 scopus 로고    scopus 로고
    • NHE1: Still a viable therapeutic target
    • Karmazyn M: NHE1: Still a viable therapeutic target. J Mol Cell Cardiol 2013; 61: 77-82
    • (2013) J Mol Cell Cardiol , vol.61 , pp. 77-82
    • Karmazyn, M.1
  • 13
    • 0026437729 scopus 로고
    • Reperfusion-induced arrhythmias: A role for washout of extracellular protons?
    • Avkiran M, Ibuki C: Reperfusion-induced arrhythmias: A role for washout of extracellular protons?. Circ Res 1992; 71: 1429-1440
    • (1992) Circ Res , vol.71 , pp. 1429-1440
    • Avkiran, M.1    Ibuki, C.2
  • 14
    • 0025254444 scopus 로고
    • Buffer agents do not reverse intramyocardial acidosis during cardiac resuscitation
    • Kette F, Weil MH, Von Planta M, Gazmuri RJ, Rackow EC: Buffer agents do not reverse intramyocardial acidosis during cardiac resuscitation. Circulation 1990; 81: 1660-1666
    • (1990) Circulation , vol.81 , pp. 1660-1666
    • Kette, F.1    Weil, M.H.2    Von Planta, M.3    Gazmuri, R.J.4    Rackow, E.C.5
  • 15
    • 40949133820 scopus 로고    scopus 로고
    • Na + /H + exchange inhibition delays the onset of hypovolemic circulatory shock in pigs
    • Wu DM, Arias J, Bassuk J, et al: Na + /H + exchange inhibition delays the onset of hypovolemic circulatory shock in pigs. Shock 2008; 29: 519-525
    • (2008) Shock , vol.29 , pp. 519-525
    • Wu, D.M.1    Arias, J.2    Bassuk, J.3
  • 16
    • 84876413711 scopus 로고    scopus 로고
    • NHE1 inhibition improves tissue perfusion and resuscitation outcome after severe hemorrhage
    • Wu D, Russano K, Kouz I, Abraham WM: NHE1 inhibition improves tissue perfusion and resuscitation outcome after severe hemorrhage. J Surg Res 2013; 181:e75-e81
    • (2013) J Surg Res , vol.181
    • Wu, D.1    Russano, K.2    Kouz, I.3    Abraham, W.M.4
  • 17
    • 66449112271 scopus 로고    scopus 로고
    • Low-volume resuscitation from traumatic hemorrhagic shock with Na+/H+ exchanger inhibitor
    • Wu D, Dai H, Arias J, Latta L, Abraham WM: Low-volume resuscitation from traumatic hemorrhagic shock with Na+/H+ exchanger inhibitor. Crit Care Med 2009; 37: 1994-1999
    • (2009) Crit Care Med , vol.37 , pp. 1994-1999
    • Wu, D.1    Dai, H.2    Arias, J.3    Latta, L.4    Abraham, W.M.5
  • 18
    • 77649087367 scopus 로고    scopus 로고
    • Resuscitation with Na + /H + exchanger inhibitor in traumatic haemorrhagic shock: Cardiopulmonary performance, oxygen transport and tissue inflammation
    • Wu DM, Qi JS, Dai H, Doods H, Abraham WM: Resuscitation with Na + /H + exchanger inhibitor in traumatic haemorrhagic shock: Cardiopulmonary performance, oxygen transport and tissue inflammation. Clin Exp Pharmacol Physiol 2010; 37: 337-342
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 337-342
    • Wu, D.M.1    Qi, J.S.2    Dai, H.3    Doods, H.4    Abraham, W.M.5
  • 19
    • 84860469840 scopus 로고    scopus 로고
    • Mechanisms of the beneficial effect of NHE1 inhibitor in traumatic hemorrhage: Inhibition of inflammatory pathways
    • Wu D, Qi J: Mechanisms of the beneficial effect of NHE1 inhibitor in traumatic hemorrhage: Inhibition of inflammatory pathways. Resuscitation 2012; 83: 774-781
    • (2012) Resuscitation , vol.83 , pp. 774-781
    • Wu, D.1    Qi, J.2
  • 20
    • 84872259027 scopus 로고    scopus 로고
    • Sabiporide improves cardiovascular function, decreases the inflammatory response, and reduces mortality in acute metabolic acidosis in pigs
    • Wu DM, Kraut JA, Abraham WM: Sabiporide improves cardiovascular function, decreases the inflammatory response, and reduces mortality in acute metabolic acidosis in pigs. PLoS One 2013; 8:e593932-593938
    • (2013) PLoS One , vol.8
    • Wu, D.M.1    Kraut, J.A.2    Abraham, W.M.3
  • 21
    • 84875247413 scopus 로고    scopus 로고
    • Protective effects of NHE1 inhibition with sabiporide in an experimental model of asphyxia-induced cardiac arrest in piglets
    • Lin X, Lee D, Wu D: Protective effects of NHE1 inhibition with sabiporide in an experimental model of asphyxia-induced cardiac arrest in piglets. Resuscitation 2013; 84: 520-525
    • (2013) Resuscitation , vol.84 , pp. 520-525
    • Lin, X.1    Lee, D.2    Wu, D.3
  • 22
    • 84874108321 scopus 로고    scopus 로고
    • Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model
    • Robertson NJ, Kato T, Bainbridge A, et al: Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model. J Neurochem 2013; 124: 645-657
    • (2013) J Neurochem , vol.124 , pp. 645-657
    • Robertson, N.J.1    Kato, T.2    Bainbridge, A.3
  • 23
    • 84870177177 scopus 로고    scopus 로고
    • Acid extrusion via blood-brain barrier causes brain alkalosis and seizures after neonatal asphyxia
    • Helmy MM, Ruusuvuori E, Watkins PV, Voipio J, Kanold PO, Kaila K: Acid extrusion via blood-brain barrier causes brain alkalosis and seizures after neonatal asphyxia. Brain 2012; 135: 3311-3319
    • (2012) Brain , vol.135 , pp. 3311-3319
    • Helmy, M.M.1    Ruusuvuori, E.2    Watkins, P.V.3    Voipio, J.4    Kanold, P.O.5    Kaila, K.6
  • 24
    • 0023930836 scopus 로고
    • Improved hemodynamic function during hypoxia with carbicarb, a new agent for the management of acidosis
    • Bersin RM, Arieff AI: Improved hemodynamic function during hypoxia with carbicarb, a new agent for the management of acidosis. Circulation 1988; 77: 227-233
    • (1988) Circulation , vol.77 , pp. 227-233
    • Bersin, R.M.1    Arieff, A.I.2
  • 25
    • 0037426418 scopus 로고    scopus 로고
    • Sodiumhydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability
    • Ayoub IM, Kolarova J, Yi Z, et al: Sodiumhydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability. Circulation 2003; 107: 1804-1809
    • (2003) Circulation , vol.107 , pp. 1804-1809
    • Ayoub, I.M.1    Kolarova, J.2    Yi, Z.3
  • 26
    • 27944450760 scopus 로고    scopus 로고
    • Cariporide minimizes adverse myocardial effects of epinephrine during resuscitation from ventricular fibrillation
    • Ayoub IM, Kolarova J, Kantola RL, Sanders R, Gazmuri RJ: Cariporide minimizes adverse myocardial effects of epinephrine during resuscitation from ventricular fibrillation. Crit Care Med 2005; 33: 2599-2605
    • (2005) Crit Care Med , vol.33 , pp. 2599-2605
    • Ayoub, I.M.1    Kolarova, J.2    Kantola, R.L.3    Sanders, R.4    Gazmuri, R.J.5
  • 27
    • 34748834084 scopus 로고    scopus 로고
    • Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism
    • Ayoub IM, Kolarova JD, Kantola RL, Radhakrishnan J, Wang S, Gazmuri RJ: Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. Crit Care Med 2007; 35: 2329-2336
    • (2007) Crit Care Med , vol.35 , pp. 2329-2336
    • Ayoub, I.M.1    Kolarova, J.D.2    Kantola, R.L.3    Radhakrishnan, J.4    Wang, S.5    Gazmuri, R.J.6
  • 28
    • 33646574933 scopus 로고    scopus 로고
    • The case for sodiumhydrogen exchanger isoform-1 inhibition during cardiac resuscitation remains strong
    • Gazmuri RJ, Ayoub IM: The case for sodiumhydrogen exchanger isoform-1 inhibition during cardiac resuscitation remains strong. Crit Care Med 2006; 34: 1580-1582
    • (2006) Crit Care Med , vol.34 , pp. 1580-1582
    • Gazmuri, R.J.1    Ayoub, I.M.2
  • 29
    • 0036215144 scopus 로고    scopus 로고
    • Myocardial protection during ventricular fibrillation by inhibition of the sodiumhydrogen exchanger isoform-1
    • Gazmuri RJ, Ayoub IM, Kolarova JD, Karmazyn M: Myocardial protection during ventricular fibrillation by inhibition of the sodiumhydrogen exchanger isoform-1. Crit Care Med 2002; 30:S166-S171
    • (2002) Crit Care Med , vol.30
    • Gazmuri, R.J.1    Ayoub, I.M.2    Kolarova, J.D.3    Karmazyn, M.4
  • 30
    • 34447647991 scopus 로고
    • Limiting sarcolemmal Na + entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca 2+ accumulation and attenuates myocardial injury
    • Wang S, Radhakrishnan J, Ayoub IM, Kolarova JD, Taglieri DM, Gazmuri RJ: Limiting sarcolemmal Na + entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca 2+ accumulation and attenuates myocardial injury. J Appl Physiol (1985) 2007; 103: 55-65
    • (1985) J Appl Physiol , vol.2007 , Issue.103 , pp. 55-65
    • Wang, S.1    Radhakrishnan, J.2    Ayoub, I.M.3    Kolarova, J.D.4    Taglieri, D.M.5    Gazmuri, R.J.6
  • 31
    • 80052962098 scopus 로고    scopus 로고
    • Resuscitation after prolonged cardiac arrest: Effects of cardiopulmonary bypass and sodium-hydrogen exchange inhibition on myocardial and neurological recovery
    • Liakopoulos OJ, Hristov N, Buckberg GD, Triana J, Trummer G, Allen BS: Resuscitation after prolonged cardiac arrest: Effects of cardiopulmonary bypass and sodium-hydrogen exchange inhibition on myocardial and neurological recovery. Eur J Cardiothorac Surg 2011; 40: 978-984
    • (2011) Eur J Cardiothorac Surg , vol.40 , pp. 978-984
    • Liakopoulos, O.J.1    Hristov, N.2    Buckberg, G.D.3    Triana, J.4    Trummer, G.5    Allen, B.S.6
  • 32
    • 13244296850 scopus 로고    scopus 로고
    • Neurologic preservation by Na +-H + exchange inhibition prior to 90 min of hypothermic circulatory arrest
    • Castella M, Buckberg GD, Tan Z: Neurologic preservation by Na +-H + exchange inhibition prior to 90 min of hypothermic circulatory arrest. Ann Thorac Surg 2005; 79: 646-654
    • (2005) Ann Thorac Surg , vol.79 , pp. 646-654
    • Castella, M.1    Buckberg, G.D.2    Tan, Z.3
  • 34
    • 0035945680 scopus 로고    scopus 로고
    • Risk factors for cerebral edema in children with diabetic ketoacidosis
    • Glaser N, Barnett P, McCaslin I, et al: Risk factors for cerebral edema in children with diabetic ketoacidosis. N Engl J Med 2001; 344: 264-269
    • (2001) N Engl J Med , vol.344 , pp. 264-269
    • Glaser, N.1    Barnett, P.2    McCaslin, I.3
  • 35
    • 84866322474 scopus 로고    scopus 로고
    • On the origins of lactate during sepsis
    • Gibot S: On the origins of lactate during sepsis. Crit Care 2012; 16: 151
    • (2012) Crit Care , vol.16 , pp. 151
    • Gibot, S.1
  • 36
    • 77957559964 scopus 로고    scopus 로고
    • Increased muscle-To-serum lactate gradient predicts progression towards septic shock in septic patients
    • Levy B, Perez P, Gibot S, Gerard A: Increased muscle-To-serum lactate gradient predicts progression towards septic shock in septic patients. Intensive Care Med 2010; 36: 1703-1709
    • (2010) Intensive Care Med , vol.36 , pp. 1703-1709
    • Levy, B.1    Perez, P.2    Gibot, S.3    Gerard, A.4
  • 37
    • 14944384277 scopus 로고    scopus 로고
    • Sodium/hydrogen exchange activity in sepsis and in sepsis complicated by previous injury: 31P and 23Na NMR study
    • Sikes PJ, Zhao P, Maass DL, White J, Horton JW: Sodium/hydrogen exchange activity in sepsis and in sepsis complicated by previous injury: 31P and 23Na NMR study. Crit Care Med 2005; 33: 605-615
    • (2005) Crit Care Med , vol.33 , pp. 605-615
    • Sikes, P.J.1    Zhao, P.2    Maass, D.L.3    White, J.4    Horton, J.W.5
  • 38
    • 84928342826 scopus 로고    scopus 로고
    • The NHE1 inhibitor Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in an experimental model of lactic acidosis in pigs
    • in press
    • Lin X, Kraut J, Wu D: The NHE1 inhibitor Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in an experimental model of lactic acidosis in pigs. Pediatr Res, in press
    • Pediatr Res
    • Lin, X.1    Kraut, J.2    Wu, D.3
  • 39
    • 0034680325 scopus 로고    scopus 로고
    • Na + /H + exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow
    • Klein HH, Pich S, Bohle RM, Lindert-Heimberg S, Nebendahl K: Na + /H + exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow. Circulation 2000; 102: 1977-1982
    • (2000) Circulation , vol.102 , pp. 1977-1982
    • Klein, H.H.1    Pich, S.2    Bohle, R.M.3    Lindert-Heimberg, S.4    Nebendahl, K.5
  • 40
    • 40749126460 scopus 로고    scopus 로고
    • Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing cardiac artery bypass grafting; results of the Expedition study
    • Mentzer RM, Bartels C, Bolti R, Boyce S, Buckberg GD, Chaitman B, et al: Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing cardiac artery bypass grafting; results of the Expedition study. Ann Thorac Surg 2008; 85: 1261-1270
    • (2008) Ann Thorac Surg , vol.85 , pp. 1261-1270
    • Mentzer, R.M.1    Bartels, C.2    Bolti, R.3    Boyce, S.4    Buckberg, G.D.5    Chaitman, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.