Potential role of NHE1 (sodium-hydrogen exchanger 1) in the cellular dysfunction of lactic acidosis: Implications for treatment

American Journal of Kidney Diseases

Volumn 57, Issue 5, 2011, Pages 781-787

  Wu, Dongmei ^a,b   Kraut, Jeffrey A ^c,d,e  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b Chonbuk National University   (South Korea)

^c VHAGLA Healthcare System   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acidosis; cell injury; lactic acidosis; Na+ H+ exchanger; NHE1; pH; SLC9A1

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; AMILORIDE; BICARBONATE; BICARBONATE SODIUM COTRANSPORTER; CALCIUM ION; CARIPORIDE; CHLORIDE; HYPERTENSIVE AGENT; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; SODIUM; SODIUM CHANNEL BLOCKING AGENT; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 1 INHIBITOR; UNCLASSIFIED DRUG;

ACID BASE BALANCE; AGED; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD PH; BLOOD PRESSURE MEASUREMENT; BODY TEMPERATURE; CALCIUM CELL LEVEL; CASE REPORT; CELL DAMAGE; CELL PH; CEREBROVASCULAR ACCIDENT; CHLORIDE BLOOD LEVEL; COMPETITIVE INHIBITION; DEATH; DISEASE PREDISPOSITION; DISEASE SEVERITY; DRUG TREATMENT FAILURE; HEART ARRHYTHMIA; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART RATE; HUMAN; HYPOTENSION; HYPOXEMIA; LACTIC ACIDOSIS; LUNG VASCULAR RESISTANCE; MALE; MEDICAL HISTORY; METABOLIC ACIDOSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PHYSICAL EXAMINATION; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; REPERFUSION INJURY; SEPSIS; SODIUM BLOOD LEVEL; SODIUM TRANSPORT; TREATMENT DURATION;

ACIDOSIS, LACTIC; AGED, 80 AND OVER; ANIMALS; CATION TRANSPORT PROTEINS; CELL MEMBRANE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; SODIUM-HYDROGEN ANTIPORTER;

EID: 79954594092     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2010.10.058     Document Type: Article

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