메뉴 건너뛰기




Volumn 35, Issue 10, 2007, Pages 2329-2336

Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism

Author keywords

Cardiopulmonary bypass; Cardiopulmonary resuscitation; Energy metabolism; Myocardial ischemia; Sodium hydrogen antiporter; Ventricular fibrillation

Indexed keywords

ADENOSINE; CREATINE; CREATINE PHOSPHATE; LACTIC ACID; SODIUM PROTON EXCHANGE PROTEIN 1; ZONIPORIDE;

EID: 34748834084     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000280569.87413.74     Document Type: Article
Times cited : (32)

References (45)
  • 2
    • 0027233862 scopus 로고
    • Intramyocardial hypercarbic acidosis during cardiac arrest and resuscitation
    • Kette F, Weil MH, Gazmuri RJ, et al: Intramyocardial hypercarbic acidosis during cardiac arrest and resuscitation. Crit Care Med 1993; 21:901-906
    • (1993) Crit Care Med , vol.21 , pp. 901-906
    • Kette, F.1    Weil, M.H.2    Gazmuri, R.J.3
  • 4
    • 0033603309 scopus 로고    scopus 로고
    • Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury
    • Imahashi K, Kusuoka H, Hashimoto K, et al: Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury. Circ Res 1999; 84:1401-1406
    • (1999) Circ Res , vol.84 , pp. 1401-1406
    • Imahashi, K.1    Kusuoka, H.2    Hashimoto, K.3
  • 5
    • 0035137946 scopus 로고    scopus 로고
    • Myocardial protection during ventricular fibrillation by reduction of proton-driven sarcolemmal sodium influx
    • Gazmuri RJ, Hoffner E, Kalcheim J, et al: Myocardial protection during ventricular fibrillation by reduction of proton-driven sarcolemmal sodium influx. J Lab Clin Med 2001; 137:43-55
    • (2001) J Lab Clin Med , vol.137 , pp. 43-55
    • Gazmuri, R.J.1    Hoffner, E.2    Kalcheim, J.3
  • 6
    • 0029871099 scopus 로고    scopus 로고
    • Effects of acidic reperfusion on arrhythmias and Na(+)-K(+)-ATPase activity in regionally ischemic rat hearts
    • Avkiran M, Ibuki C, Shimada Y, et al: Effects of acidic reperfusion on arrhythmias and Na(+)-K(+)-ATPase activity in regionally ischemic rat hearts. Am J Physiol 1996; 270:H957-H964
    • (1996) Am J Physiol , vol.270
    • Avkiran, M.1    Ibuki, C.2    Shimada, Y.3
  • 7
    • 0035661776 scopus 로고    scopus 로고
    • Blocking Na(+)/H(+) exchange reduces [Na(+)] (i) and [Ca(2+)] (i) load after ischemia and improves function in intact hearts
    • An J, Varadarajan SG, Camara A, et al: Blocking Na(+)/H(+) exchange reduces [Na(+)] (i) and [Ca(2+)] (i) load after ischemia and improves function in intact hearts. Am J Physiol 2001; 281:H2398-H2409
    • (2001) Am J Physiol , vol.281
    • An, J.1    Varadarajan, S.G.2    Camara, A.3
  • 8
    • 0036200338 scopus 로고    scopus 로고
    • Protective effect of Na+/H+ exchange inhibitor, SM-20550, on impaired mitochondrial respiratory function and mitochondrial Ca2+ overload in ischemic/reperfused rat hearts
    • Yamamoto S, Matsui K, Ohashi N: Protective effect of Na+/H+ exchange inhibitor, SM-20550, on impaired mitochondrial respiratory function and mitochondrial Ca2+ overload in ischemic/reperfused rat hearts. J Cardiovasc Pharmacol 2002; 39:569-575
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 569-575
    • Yamamoto, S.1    Matsui, K.2    Ohashi, N.3
  • 9
    • 0037464448 scopus 로고    scopus 로고
    • Mitochondria in apoptosis of ischemic heart
    • Borutaite V, Brown GC: Mitochondria in apoptosis of ischemic heart. FEBS Lett 2003; 541:1-5
    • (2003) FEBS Lett , vol.541 , pp. 1-5
    • Borutaite, V.1    Brown, G.C.2
  • 10
    • 0034919120 scopus 로고    scopus 로고
    • Protection of the ischaemic myocardium by Na+/H+ exchange inhibitors: Potential mechanisms of action
    • Avkiran M: Protection of the ischaemic myocardium by Na+/H+ exchange inhibitors: potential mechanisms of action. Basic Res Cardiol 2001; 96:306-311
    • (2001) Basic Res Cardiol , vol.96 , pp. 306-311
    • Avkiran, M.1
  • 11
    • 0035057159 scopus 로고    scopus 로고
    • The myocardial Na+/H+ exchanger: A potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure
    • Karmazyn M, Sostaric JV, Gan XT: The myocardial Na+/H+ exchanger: A potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure. Drugs 2001; 61:375-389
    • (2001) Drugs , vol.61 , pp. 375-389
    • Karmazyn, M.1    Sostaric, J.V.2    Gan, X.T.3
  • 12
    • 0035082669 scopus 로고    scopus 로고
    • A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo
    • Knight DR, Smith AH, Flynn DM, et al: A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo. J Pharmacol Exp Ther 2001; 297:254-259
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 254-259
    • Knight, D.R.1    Smith, A.H.2    Flynn, D.M.3
  • 13
    • 0035012135 scopus 로고    scopus 로고
    • HOE-642 (cariporide) alters pH (i) and diastolic function after ischemia during reperfusion in pig hearts in situ
    • Portman MA, Panos AL, Xiao Y, et al: HOE-642 (cariporide) alters pH (i) and diastolic function after ischemia during reperfusion in pig hearts in situ. Am J Physiol Heart Circ Physiol 2001; 280:H830-H834
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Portman, M.A.1    Panos, A.L.2    Xiao, Y.3
  • 14
    • 0037245499 scopus 로고    scopus 로고
    • Improved myocardial function using a Na+/H+ exchanger inhibitor during cardioplegic arrest and cardiopulmonary bypass
    • Cox CS Jr, Allen SJ, Sauer H, Laine GA: Improved myocardial function using a Na+/H+ exchanger inhibitor during cardioplegic arrest and cardiopulmonary bypass. Chest 2003; 123:187-194
    • (2003) Chest , vol.123 , pp. 187-194
    • Cox Jr, C.S.1    Allen, S.J.2    Sauer, H.3    Laine, G.A.4
  • 15
    • 10744229937 scopus 로고    scopus 로고
    • Cariporide is cardioprotective after iatrogenic ventricular fibrillation in the intact swine heart
    • Rabkin DG, Cabreriza SE, Cheema FH, et al: Cariporide is cardioprotective after iatrogenic ventricular fibrillation in the intact swine heart. Ann Thorac Surg 2003; 76:1264-1269
    • (2003) Ann Thorac Surg , vol.76 , pp. 1264-1269
    • Rabkin, D.G.1    Cabreriza, S.E.2    Cheema, F.H.3
  • 16
    • 0037426418 scopus 로고    scopus 로고
    • Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability
    • Ayoub IM, Kolarova JD, Yi Z, et al: Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability. Circulation 2003; 107:1804-1809
    • (2003) Circulation , vol.107 , pp. 1804-1809
    • Ayoub, I.M.1    Kolarova, J.D.2    Yi, Z.3
  • 17
    • 19344366139 scopus 로고    scopus 로고
    • Cariporide enables hemodynamically more effective chest compression by leftward shift of its flow-depth relationship
    • Kolarova JD, Ayoub IM, Gazmuri RJ: Cariporide enables hemodynamically more effective chest compression by leftward shift of its flow-depth relationship. Am J Physiol Heart Circ Physiol 2005; 288:H2904-H2911
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Kolarova, J.D.1    Ayoub, I.M.2    Gazmuri, R.J.3
  • 18
    • 0035838403 scopus 로고    scopus 로고
    • Successful ventricular defibrillation by the selective sodium-hydrogen exchanger isoform-1 inhibitor cariporide
    • Gazmuri RJ, Ayoub IM, Hoffner E, et al: Successful ventricular defibrillation by the selective sodium-hydrogen exchanger isoform-1 inhibitor cariporide. Circulation 2001; 104:234-239
    • (2001) Circulation , vol.104 , pp. 234-239
    • Gazmuri, R.J.1    Ayoub, I.M.2    Hoffner, E.3
  • 19
    • 19044367954 scopus 로고    scopus 로고
    • Cariporide potentiates the effects of epinephrine and vasopressin by nonvascular mechanisms during closed-chest resuscitation
    • Kolarova J, Yi Z, Ayoub IM, et al: Cariporide potentiates the effects of epinephrine and vasopressin by nonvascular mechanisms during closed-chest resuscitation. Chest 2005; 127:1327-1334
    • (2005) Chest , vol.127 , pp. 1327-1334
    • Kolarova, J.1    Yi, Z.2    Ayoub, I.M.3
  • 21
    • 0018508961 scopus 로고
    • Quantitative study of intramyocardial compression in the fibrillating heart
    • Downey JM, Chagrasulis RW, Hemphill V: Quantitative study of intramyocardial compression in the fibrillating heart. Am J Physiol 1979; 237:H191-H196
    • (1979) Am J Physiol , vol.237
    • Downey, J.M.1    Chagrasulis, R.W.2    Hemphill, V.3
  • 22
    • 33747103243 scopus 로고    scopus 로고
    • Textbook of Clinical Echocardiography. Philadelphia, Elsevier Saunders
    • Otto CM. Left and Right Ventricular Systolic Function. In: Textbook of Clinical Echocardiography. Philadelphia, Elsevier Saunders, 2004, pp 131-163
    • (2004) Left and Right Ventricular Systolic Function , pp. 131-163
    • Otto, C.M.1
  • 24
    • 0028019584 scopus 로고
    • Peak systolic pressure/end-systolic volume ratio, a load-independent measure of ventricular function, is reversibly decreased in human septic shock
    • Parker MM, Ognibene FP, Parrillo JE: Peak systolic pressure/end-systolic volume ratio, a load-independent measure of ventricular function, is reversibly decreased in human septic shock. Crit Care Med 1994; 22:1955-1959
    • (1994) Crit Care Med , vol.22 , pp. 1955-1959
    • Parker, M.M.1    Ognibene, F.P.2    Parrillo, J.E.3
  • 25
    • 0029981206 scopus 로고    scopus 로고
    • Load-independent left ventricular function in a hemorrhagic shock model
    • Chendrasekhar A, Barringer LS, Fagerli JC, et al: Load-independent left ventricular function in a hemorrhagic shock model. J Surg Res 1996; 62:49-52
    • (1996) J Surg Res , vol.62 , pp. 49-52
    • Chendrasekhar, A.1    Barringer, L.S.2    Fagerli, J.C.3
  • 26
    • 0018092662 scopus 로고
    • Effects on labile metabolites of temporal delay in freezing biopsy samples of dog myocardium in liquid nitrogen
    • Allison TB, Ramey CA, Holsinger JW Jr: Effects on labile metabolites of temporal delay in freezing biopsy samples of dog myocardium in liquid nitrogen. Cardiovasc Res 1978; 12:162-166
    • (1978) Cardiovasc Res , vol.12 , pp. 162-166
    • Allison, T.B.1    Ramey, C.A.2    Holsinger Jr, J.W.3
  • 27
    • 0035946035 scopus 로고    scopus 로고
    • Determination of high-energy phosphate compounds and inorganic phosphate by reversed-phase high-performance liquid chromatography: Evaluation of myocardial metabolic status in aerobically perfused and hypoxic mouse heart
    • Tomasetti M, Graciotti L, Fulgenzi G, et al: Determination of high-energy phosphate compounds and inorganic phosphate by reversed-phase high-performance liquid chromatography: Evaluation of myocardial metabolic status in aerobically perfused and hypoxic mouse heart. J Chromatogr B Biomed Sci Appl 2001; 751:229-236
    • (2001) J Chromatogr B Biomed Sci Appl , vol.751 , pp. 229-236
    • Tomasetti, M.1    Graciotti, L.2    Fulgenzi, G.3
  • 28
    • 0000831016 scopus 로고
    • Determination with LDH, GPT and NAD
    • Bergmeyer HU Ed, New York and London, Academic Press
    • Noll F: Determination with LDH, GPT and NAD. In: Bergmeyer HU (Ed). Methods of Enzymatic Analysis. New York and London, Academic Press, 1974, pp 1475-1479
    • (1974) Methods of Enzymatic Analysis , pp. 1475-1479
    • Noll, F.1
  • 29
    • 0035953078 scopus 로고    scopus 로고
    • Discovery of zoniporide: A potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility
    • Guzman-Perez A, Wester RT, Allen MC, et al: Discovery of zoniporide: A potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett 2001; 11:803-807
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 803-807
    • Guzman-Perez, A.1    Wester, R.T.2    Allen, M.C.3
  • 30
    • 0030038503 scopus 로고    scopus 로고
    • Creatine phosphate as the preferred early indicator of ischemia in muscular tissues
    • Ye J, Clark MG, Colquhoun EQ: Creatine phosphate as the preferred early indicator of ischemia in muscular tissues. J Surg Res 1996; 61:227-236
    • (1996) J Surg Res , vol.61 , pp. 227-236
    • Ye, J.1    Clark, M.G.2    Colquhoun, E.Q.3
  • 31
    • 0025156055 scopus 로고
    • Cardiac effects of carbon dioxide-consuming and carbon dioxide- generating buffers during cardiopulmonary resuscitation
    • Gazmuri RJ, von Planta M, Weil MH, et al: Cardiac effects of carbon dioxide-consuming and carbon dioxide- generating buffers during cardiopulmonary resuscitation. J Am Coll Cardiol 1990; 15:482-490
    • (1990) J Am Coll Cardiol , vol.15 , pp. 482-490
    • Gazmuri, R.J.1    von Planta, M.2    Weil, M.H.3
  • 32
    • 0036384410 scopus 로고    scopus 로고
    • Evolution of the stone heart after prolonged cardiac arrest
    • Klouche K, Weil MH, Sun S, et al: Evolution of the stone heart after prolonged cardiac arrest. Chest 2002; 122:1006-1011
    • (2002) Chest , vol.122 , pp. 1006-1011
    • Klouche, K.1    Weil, M.H.2    Sun, S.3
  • 33
    • 0030462333 scopus 로고    scopus 로고
    • Firm myocardium in cardiopulmonary resuscitation
    • Takino M, Okada Y: Firm myocardium in cardiopulmonary resuscitation. Resuscitation 1996; 33:101-106
    • (1996) Resuscitation , vol.33 , pp. 101-106
    • Takino, M.1    Okada, Y.2
  • 34
    • 0032817879 scopus 로고    scopus 로고
    • Myocardial effects of ventricular fibrillation in the isolated rat heart
    • Gazmuri RJ, Berkowitz M, Cajigas H: Myocardial effects of ventricular fibrillation in the isolated rat heart. Crit Care Med 1999; 27:1542-1550
    • (1999) Crit Care Med , vol.27 , pp. 1542-1550
    • Gazmuri, R.J.1    Berkowitz, M.2    Cajigas, H.3
  • 36
    • 0027529081 scopus 로고
    • Heterogeneity of the hypoxic state in rat heart is determined at capillary level
    • Ince C, Ashruf JF, Avontuur JA, et al: Heterogeneity of the hypoxic state in rat heart is determined at capillary level. Am J Physiol 1993; 264:H294-H301
    • (1993) Am J Physiol , vol.264
    • Ince, C.1    Ashruf, J.F.2    Avontuur, J.A.3
  • 37
    • 0035920253 scopus 로고    scopus 로고
    • Energetic crosstalk between organelles: Architectural integration of energy production and utilization
    • Kaasik A, Veksler V, Boehm E, et al: Energetic crosstalk between organelles: Architectural integration of energy production and utilization. Circ Res 2001; 89:153-159
    • (2001) Circ Res , vol.89 , pp. 153-159
    • Kaasik, A.1    Veksler, V.2    Boehm, E.3
  • 38
    • 4444286823 scopus 로고    scopus 로고
    • Transgenesis and cardiac energetics: New insights into cardiac metabolism
    • Ingwall JS: Transgenesis and cardiac energetics: New insights into cardiac metabolism. J Mol Cell Cardiol 2004; 37:613-623
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 613-623
    • Ingwall, J.S.1
  • 39
    • 0021891892 scopus 로고
    • The creatine-creatine phosphate energy shuttle
    • Bessman SP, Carpenter CL: The creatine-creatine phosphate energy shuttle. Annu Rev Biochem 1985; 54:831-862
    • (1985) Annu Rev Biochem , vol.54 , pp. 831-862
    • Bessman, S.P.1    Carpenter, C.L.2
  • 40
    • 33645897315 scopus 로고    scopus 로고
    • Cardiac system bioenergetics: Metabolic basis of the Frank-Starling law
    • Saks V, Dzeja P, Schlattner U, et al: Cardiac system bioenergetics: Metabolic basis of the Frank-Starling law. J Physiol 2006; 571:253-273
    • (2006) J Physiol , vol.571 , pp. 253-273
    • Saks, V.1    Dzeja, P.2    Schlattner, U.3
  • 41
    • 34748894158 scopus 로고    scopus 로고
    • Quantitative Bioenergetics: The Measurement of Driving Forces. In: Nicholls DG, Ferguson SJ (Eds). Bioenergetics3. London, Academic Press, 2002, pp 31-52
    • Quantitative Bioenergetics: The Measurement of Driving Forces. In: Nicholls DG, Ferguson SJ (Eds). Bioenergetics3. London, Academic Press, 2002, pp 31-52
  • 42
    • 0022559199 scopus 로고
    • Mechanisms and consequences of pH-mediated cell regulation
    • Busa WB: Mechanisms and consequences of pH-mediated cell regulation. Annu Rev Physiol 1986; 48:389-402
    • (1986) Annu Rev Physiol , vol.48 , pp. 389-402
    • Busa, W.B.1
  • 43
    • 0027339828 scopus 로고
    • Mechanisms of pHi recovery after global ischemia in the perfused heart
    • Vandenberg JI, Metcalfe JC, Grace AA: Mechanisms of pHi recovery after global ischemia in the perfused heart. Circ Res 1993; 72:993-1003
    • (1993) Circ Res , vol.72 , pp. 993-1003
    • Vandenberg, J.I.1    Metcalfe, J.C.2    Grace, A.A.3
  • 44
    • 0842309103 scopus 로고    scopus 로고
    • Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia
    • Lin H, Suleiman MS: Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia. Pflugers Arch 2003; 447:8-13
    • (2003) Pflugers Arch , vol.447 , pp. 8-13
    • Lin, H.1    Suleiman, M.S.2
  • 45
    • 0036817178 scopus 로고    scopus 로고
    • Myocardial protection by anesthetic agents against ischemia-reperfusion injury: An update for anesthesiologists
    • Kato R, Foex P: Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Can J Anaesth 2002; 49:777-791
    • (2002) Can J Anaesth , vol.49 , pp. 777-791
    • Kato, R.1    Foex, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.