-
1
-
-
84864390703
-
Pre-mRNA splicing in disease and therapeutics
-
PMID:22819011
-
Singh RK, Cooper TA. Pre-mRNA splicing in disease and therapeutics. Trends Mol Med 2012 18:472-82 PMID:22819011 http://dx.doi.org/10.1016/j. molmed.2012.06.006
-
(2012)
Trends Mol Med
, vol.18
, pp. 472-482
-
-
Singh, R.K.1
Cooper, T.A.2
-
2
-
-
84863680893
-
Functional roles of protein splicing factors
-
PMID:22762203
-
Chen HC, Cheng SC. Functional roles of protein splicing factors. Biosci Rep 2012 32:345-59 PMID:22762203 http://dx.doi.org/10.1042/BSR20120007
-
(2012)
Biosci Rep
, vol.32
, pp. 345-359
-
-
Chen, H.C.1
Cheng, S.C.2
-
3
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
PMID:19239890
-
Wahl MC, Will CL, Lührmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009 136:701-18 PMID:19239890 http://dx.doi. org/10.1016/j.cell.2009.02.009
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Lührmann, R.3
-
4
-
-
0141924550
-
The Prp19passociated complex in spliceosome activation
-
PMID:12970570
-
Chan SP, Kao DI, Tsai WY, Cheng SC. The Prp19passociated complex in spliceosome activation. Science 2003 302:279-82 PMID:12970570 http://dx.doi. org/10.1126/science.1086602
-
(2003)
Science
, vol.302
, pp. 279-282
-
-
Chan, S.P.1
Kao, D.I.2
Tsai, W.Y.3
Cheng, S.C.4
-
5
-
-
77955929156
-
The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing
-
PMID:20659013
-
Hogg R, McGrail JC, O’Keefe RT. The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing. Biochem Soc Trans 2010 38:1110-5 PMID:20659013 http://dx.doi.org/10.1042/BST0381110
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1110-1115
-
-
Hogg, R.1
McGrail, J.C.2
O’Keefe, R.T.3
-
6
-
-
84857301751
-
Saccharomyces cerevisiae NineTeen complex (NTC)- associated factor Bud31/Ycr063w assembles on precatalytic spliceosomes and improves first and second step pre-mRNA splicing efficiency
-
PMID:22215661
-
Saha D, Khandelia P, O’Keefe RT, Vijayraghavan U. Saccharomyces cerevisiae NineTeen complex (NTC)- associated factor Bud31/Ycr063w assembles on precatalytic spliceosomes and improves first and second step pre-mRNA splicing efficiency. J Biol Chem 2012 287:5390-9 PMID:22215661 http://dx.doi.org/ 10.1074/jbc.M111.298547
-
(2012)
J Biol Chem
, vol.287
, pp. 5390-5399
-
-
Saha, D.1
Khandelia, P.2
O’keefe, R.T.3
Vijayraghavan, U.4
-
7
-
-
84861394737
-
Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS
-
PMID:22535589
-
Ohrt T, Prior M, Dannenberg J, Odenwalder P, Dybkov O, Rasche N, Schmitzova J, Gregor I, Fabrizio P, Enderlein J, et al. Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 2012 18:1244-56 PMID:22535589 http://dx. doi.org/10.1261/rna.033316.112
-
(2012)
RNA
, vol.18
, pp. 1244-1256
-
-
Ohrt, T.1
Prior, M.2
Dannenberg, J.3
Odenwalder, P.4
Dybkov, O.5
Rasche, N.6
Schmitzova, J.7
Gregor, I.8
Fabrizio, P.9
Enderlein, J.10
-
8
-
-
84879311174
-
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system
-
PMID:23685439
-
Ohrt T, Odenwalder P, Dannenberg J, Prior M, Warkocki Z, Schmitzova J, Karaduman R, Gregor I, Enderlein J, Fabrizio P, et al. Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA 2013 19:902-15 PMID:23685439 http://dx. doi.org/10.1261/rna.039024.113
-
(2013)
RNA
, vol.19
, pp. 902-915
-
-
Ohrt, T.1
Odenwalder, P.2
Dannenberg, J.3
Prior, M.4
Warkocki, Z.5
Schmitzova, J.6
Karaduman, R.7
Gregor, I.8
Enderlein, J.9
Fabrizio, P.10
-
9
-
-
84875174459
-
RNA helicases in splicing
-
PMID:23229095
-
Cordin O, Beggs JD. RNA helicases in splicing. RNA Biol 2013 10:83-95 PMID:23229095 http://dx.doi. org/10.4161/rna.22547
-
(2013)
RNA Biol
, vol.10
, pp. 83-95
-
-
Cordin, O.1
Beggs, J.D.2
-
10
-
-
78650854687
-
RNA helicases at work: Binding and rearranging
-
PMID:20813532
-
Jankowsky E. RNA helicases at work: binding and rearranging. Trends Biochem Sci 2011 36:19-29 PMID:20813532 http://dx.doi.org/10.1016/j. tibs.2010.07.008
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 19-29
-
-
Jankowsky, E.1
-
11
-
-
0027287852
-
A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
-
PMID:8324826
-
Burgess SM, Guthrie C. A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell 1993 73:1377-91 PMID:8324826 http://dx.doi.org/10.1016/0092-8674 (93)90363-U
-
(1993)
Cell
, vol.73
, pp. 1377-1391
-
-
Burgess, S.M.1
Guthrie, C.2
-
12
-
-
77955488349
-
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5’ splice site cleavage during pre-mRNA splicing
-
PMID:20705241
-
Koodathingal P, Novak T, Piccirilli JA, Staley JP. The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5’ splice site cleavage during pre-mRNA splicing. Mol Cell 2010 39:385-95 PMID:20705241 http://dx.doi.org/10.1016/j.molcel.2010.07.014
-
(2010)
Mol Cell
, vol.39
, pp. 385-395
-
-
Koodathingal, P.1
Novak, T.2
Piccirilli, J.A.3
Staley, J.P.4
-
13
-
-
84880886988
-
Splicing fidelity: DEAD/Hbox ATPases as molecular clocks
-
PMID:23770752
-
Koodathingal P, Staley JP. Splicing fidelity: DEAD/Hbox ATPases as molecular clocks. RNA Biol 2013 10:1073-9 PMID:23770752 http://dx.doi.org/ 10.4161/rna.25245
-
(2013)
RNA Biol
, vol.10
, pp. 1073-1079
-
-
Koodathingal, P.1
Staley, J.P.2
-
14
-
-
44949246374
-
"Nought may endure but mutability": Spliceosome dynamics and the regulation of splicing
-
PMID:18570869
-
Smith DJ, Query CC, Konarska MM. "Nought may endure but mutability": Spliceosome dynamics and the regulation of splicing. Mol Cell 2008 30:657-66 PMID:18570869 http://dx.doi.org/10.1016/j. molcel.2008.04.013
-
(2008)
Mol Cell
, vol.30
, pp. 657-666
-
-
Smith, D.J.1
Query, C.C.2
Konarska, M.M.3
-
15
-
-
84894228514
-
The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome
-
PMID:24442613
-
Wlodaver AM, Staley JP. The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome. RNA 2014 20:282-94 PMID:24442613 http://dx.doi.org/10.1261/ rna.042598.113
-
(2014)
RNA
, vol.20
, pp. 282-294
-
-
Wlodaver, A.M.1
Staley, J.P.2
-
16
-
-
70449625597
-
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome
-
PMID:19941820
-
Fabrizio P, Dannenberg J, Dube P, Kastner B, Stark H, Urlaub H, Lührmann R. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 2009 36:593-608 PMID:19941820 http://dx.doi.org/10.1016/j. molcel.2009.09.040
-
(2009)
Mol Cell
, vol.36
, pp. 593-608
-
-
Fabrizio, P.1
Dannenberg, J.2
Dube, P.3
Kastner, B.4
Stark, H.5
Urlaub, H.6
Lührmann, R.7
-
17
-
-
84874268195
-
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system
-
PMID:23431055
-
Fourmann JB, Schmitzova J, Christian H, Urlaub H, Ficner R, Boon KL, Fabrizio P, Luhrmann R. Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes Dev 2013 27:413-28 PMID:23431055 http://dx.doi.org/ 10.1101/gad.207779.112
-
(2013)
Genes Dev
, vol.27
, pp. 413-428
-
-
Fourmann, J.B.1
Schmitzova, J.2
Christian, H.3
Urlaub, H.4
Ficner, R.5
Boon, K.L.6
Fabrizio, P.7
Luhrmann, R.8
-
18
-
-
11144320747
-
Structural and functional analysis of essential pre-mRNA splicingfactor Prp19p
-
PMID:15601865
-
Ohi MD, Vander Kooi CW, Rosenberg JA, Ren L, Hirsch JP, Chazin WJ, Walz T, Gould KL. Structural and functional analysis of essential pre-mRNA splicingfactor Prp19p. Mol Cell Biol 2005 25:451-60 PMID:15601865 http://dx.doi.org/10.1128/MCB. 25.1.451-460.2005
-
(2005)
Mol Cell Biol
, vol.25
, pp. 451-460
-
-
Ohi, M.D.1
Vander Kooi, C.W.2
Rosenberg, J.A.3
Ren, L.4
Hirsch, J.P.5
Chazin, W.J.6
Walz, T.7
Gould, K.L.8
-
19
-
-
77952666620
-
The Prp19 WD40 domain contains a conserved protein interaction region essential for its function
-
PMID:20462492
-
Vander Kooi CW, Ren L, Xu P, Ohi MD, Gould KL, Chazin WJ. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. Structure 2010 18:584-93 PMID:20462492 http://dx.doi.org/10.1016/j.str.2010.02.015
-
(2010)
Structure
, vol.18
, pp. 584-593
-
-
Vander Kooi, C.W.1
Ren, L.2
Xu, P.3
Ohi, M.D.4
Gould, K.L.5
Chazin, W.J.6
-
20
-
-
67949106544
-
The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during premRNA splicing
-
PMID:19435883
-
McGrail JC, Krause A, O’Keefe RT. The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during premRNA splicing. Nucleic Acids Res 2009 37:4205-17 PMID:19435883 http://dx.doi.org/10.1093/nar/gkp341
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4205-4217
-
-
McGrail, J.C.1
Krause, A.2
O’keefe, R.T.3
-
21
-
-
84858799296
-
Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre
-
PMID:22246180
-
Rasche N, Dybkov O, Schmitzova J, Akyildiz B, Fabrizio P, Lührmann R. Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO J 2012 31:1591-604 PMID:22246180 http://dx.doi.org/10.1038/ emboj.2011.502
-
(2012)
EMBO J
, vol.31
, pp. 1591-1604
-
-
Rasche, N.1
Dybkov, O.2
Schmitzova, J.3
Akyildiz, B.4
Fabrizio, P.5
Lührmann, R.6
-
22
-
-
84908170400
-
Structural and Functional Insights into the N-Terminus of Schizosaccharomyces pombe Cdc5
-
PMID:25263959
-
Collier SE, Voehler M, Peng D, Ohi R, Gould KL, Reiter NJ, Ohi MD. Structural and Functional Insights into the N-Terminus of Schizosaccharomyces pombe Cdc5. Biochemistry 2014 53:6439-51 PMID:25263959 http:// dx.doi.org/10.1021/bi5008639
-
(2014)
Biochemistry
, vol.53
, pp. 6439-6451
-
-
Collier, S.E.1
Voehler, M.2
Peng, D.3
Ohi, R.4
Gould, K.L.5
Reiter, N.J.6
Ohi, M.D.7
-
23
-
-
0029965552
-
Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing
-
PMID:8943336
-
Kim SH, Lin RJ. Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing. Mol Cell Biol 1996 16:6810-9 PMID:8943336
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6810-6819
-
-
Kim, S.H.1
Lin, R.J.2
-
24
-
-
77149180424
-
Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing
-
PMID:20089683
-
Lardelli RM, Thompson JX, Yates JR, 3rd, Stevens SW. Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA 2010 16:516-28 PMID:20089683 http://dx.doi.org/ 10.1261/rna.2030510
-
(2010)
RNA
, vol.16
, pp. 516-528
-
-
Lardelli, R.M.1
Thompson, J.X.2
Yates, J.R.3
Stevens, S.W.4
-
25
-
-
71449119694
-
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components
-
PMID:19935684
-
Warkocki Z, Odenwalder P, Schmitzova J, Platzmann F, Stark H, Urlaub H, Ficner R, Fabrizio P, Lührmann R. Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol 2009 16:1237-43 PMID:19935684 http://dx.doi.org/10.1038/nsmb.1729
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1237-1243
-
-
Warkocki, Z.1
Odenwalder, P.2
Schmitzova, J.3
Platzmann, F.4
Stark, H.5
Urlaub, H.6
Ficner, R.7
Fabrizio, P.8
Lührmann, R.9
-
26
-
-
70350532246
-
Cwc25 is a novel splicing factor required after Prp2 and Yju2 to facilitate the first catalytic reaction
-
PMID:19704000
-
Chiu YF, Liu YC, Chiang TW, Yeh TC, Tseng CK, Wu NY, Cheng SC. Cwc25 is a novel splicing factor required after Prp2 and Yju2 to facilitate the first catalytic reaction. Mol Cell Biol 2009 29:5671-8 PMID:19704000 http://dx.doi.org/10.1128/ MCB.00773-09
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5671-5678
-
-
Chiu, Y.F.1
Liu, Y.C.2
Chiang, T.W.3
Yeh, T.C.4
Tseng, C.K.5
Wu, N.Y.6
Cheng, S.C.7
-
27
-
-
0029312195
-
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing
-
PMID:7493316
-
Roy J, Kim K, Maddock JR, Anthony JG, Woolford JL, Jr. The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing. RNA 1995 1:375-90 PMID:7493316
-
(1995)
RNA
, vol.1
, pp. 375-390
-
-
Roy, J.1
Kim, K.2
Maddock, J.R.3
Anthony, J.G.4
Woolford, J.L.5
-
28
-
-
8644284892
-
Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing
-
PMID:15542821
-
Silverman EJ, Maeda A, Wei J, Smith P, Beggs JD, Lin RJ. Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol 2004 24:10101-10 PMID:15542821 http://dx.doi.org/10.1128/MCB. 24.23.10101-10110.2004
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10101-10110
-
-
Silverman, E.J.1
Maeda, A.2
Wei, J.3
Smith, P.4
Beggs, J.D.5
Lin, R.J.6
-
29
-
-
78751686704
-
Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway
-
PMID:20956557
-
Yeh TC, Liu HL, Chung CS, Wu NY, Liu YC, Cheng SC. Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway. Mol Cell Biol 2011 31:43-53 PMID:20956557 http://dx.doi.org/10.1128/MCB.00801-10
-
(2011)
Mol Cell Biol
, vol.31
, pp. 43-53
-
-
Yeh, T.C.1
Liu, H.L.2
Chung, C.S.3
Wu, N.Y.4
Liu, Y.C.5
Cheng, S.C.6
-
30
-
-
67649354912
-
Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps
-
PMID:19458033
-
Mefford MA, Staley JP. Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps. RNA 2009 15:1386-97 PMID:19458033 http://dx.doi.org/ 10.1261/rna.1582609
-
(2009)
RNA
, vol.15
, pp. 1386-1397
-
-
Mefford, M.A.1
Staley, J.P.2
-
31
-
-
0027065506
-
A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis
-
PMID:1464325
-
Schwer B, Guthrie C. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis. EMBO J 1992 11:5033-9 PMID:1464325
-
(1992)
EMBO J
, vol.11
, pp. 5033-5039
-
-
Schwer, B.1
Guthrie, C.2
-
32
-
-
78650446117
-
DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps
-
PMID:21098140
-
Tseng CK, Liu HL, Cheng SC. DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 2011 17:145-54 PMID:21098140 http://dx.doi.org/10.1261/rna.2459611
-
(2011)
RNA
, vol.17
, pp. 145-154
-
-
Tseng, C.K.1
Liu, H.L.2
Cheng, S.C.3
-
33
-
-
0026486883
-
A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome
-
PMID:1423631
-
Madhani HD, Guthrie C. A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome. Cell 1992 71:803-17 PMID:1423631 http://dx.doi.org/ 10.1016/0092-8674(92)90556-R
-
(1992)
Cell
, vol.71
, pp. 803-817
-
-
Madhani, H.D.1
Guthrie, C.2
-
34
-
-
84887624226
-
RNA catalyses nuclear pre-mRNA splicing
-
PMID:24196718
-
Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA. RNA catalyses nuclear pre-mRNA splicing. Nature 2013 503:229-34 PMID:24196718
-
(2013)
Nature
, vol.503
, pp. 229-234
-
-
Fica, S.M.1
Tuttle, N.2
Novak, T.3
Li, N.S.4
Lu, J.5
Koodathingal, P.6
Dai, Q.7
Staley, J.P.8
Piccirilli, J.A.9
-
35
-
-
75649116868
-
A structural analysis of the group II intron active site and implications for the spliceosome
-
PMID:19948765
-
Keating KS, Toor N, Perlman PS, Pyle AM. A structural analysis of the group II intron active site and implications for the spliceosome. RNA 2010 16:1-9 PMID:19948765 http://dx.doi.org/10.1261/rna.1791310
-
(2010)
RNA
, vol.16
, pp. 1-9
-
-
Keating, K.S.1
Toor, N.2
Perlman, P.S.3
Pyle, A.M.4
-
36
-
-
78149354420
-
Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs
-
PMID:20826700
-
Lee C, Jaladat Y, Mohammadi A, Sharifi A, Geisler S, Valadkhan S. Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs. RNA 2010 16:2226-38 PMID:20826700 http://dx.doi.org/10.1261/ rna.2170910
-
(2010)
RNA
, vol.16
, pp. 2226-2238
-
-
Lee, C.1
Jaladat, Y.2
Mohammadi, A.3
Sharifi, A.4
Geisler, S.5
Valadkhan, S.6
-
37
-
-
0028276521
-
Genetic interactions between the yeast RNA helicase homolog Prp16 and spliceosomal snRNAs identify candidate ligands for the Prp16 RNA-dependent ATPase
-
PMID:8088513
-
Madhani HD, Guthrie C. Genetic interactions between the yeast RNA helicase homolog Prp16 and spliceosomal snRNAs identify candidate ligands for the Prp16 RNA-dependent ATPase. Genetics 1994 137:677-87 PMID:8088513
-
(1994)
Genetics
, vol.137
, pp. 677-687
-
-
Madhani, H.D.1
Guthrie, C.2
-
38
-
-
23944469448
-
The Isy1p component of the Nine- Teen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
-
PMID:16103217
-
Villa T, Guthrie C. The Isy1p component of the Nine- Teen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing. Genes Dev 2005 19:1894-904 PMID:16103217 http://dx.doi. org/10.1101/gad.1336305
-
(2005)
Genes Dev
, vol.19
, pp. 1894-1904
-
-
Villa, T.1
Guthrie, C.2
-
39
-
-
84904016400
-
Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2
-
PMID:24848011
-
Hogg R, de Almeida RA, Ruckshanthi JP, O’Keefe RT. Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2. Nucleic Acids Res 2014 42:8008-23 PMID:24848011 http://dx.doi.org/10.1093/nar/gku431
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 8008-8023
-
-
Hogg, R.1
De Almeida, R.A.2
Ruckshanthi, J.P.3
O’keefe, R.T.4
-
40
-
-
0026088747
-
Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes
-
PMID:1992352
-
Company M, Arenas J, Abelson J. Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes. Nature 1991 349:487-93 PMID:1992352 http://dx.doi.org/10.1038/349487a0
-
(1991)
Nature
, vol.349
, pp. 487-493
-
-
Company, M.1
Arenas, J.2
Abelson, J.3
-
41
-
-
0032055765
-
Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
-
PMID:9524130
-
Schwer B, Gross CH. Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing. EMBO J 1998 17:2086-94 PMID:9524130 http://dx.doi.org/10.1093/emboj/17.7.2086
-
(1998)
EMBO J
, vol.17
, pp. 2086-2094
-
-
Schwer, B.1
Gross, C.H.2
-
42
-
-
39449114521
-
The U1, U2 and U5 snRNAs crosslink to the 50 exon during yeast premRNA splicing
-
PMID:18084028
-
McGrail JC, O’Keefe RT. The U1, U2 and U5 snRNAs crosslink to the 50 exon during yeast premRNA splicing. Nucleic Acids Res 2008 36:814-25 PMID:18084028 http://dx.doi.org/10.1093/nar/ gkm1098
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 814-825
-
-
McGrail, J.C.1
O’keefe, R.T.2
-
43
-
-
33748029810
-
Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing
-
PMID:16888626
-
McGrail JC, Tatum EM, O0Keefe RT. Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing. EMBO J 2006 25:3813-22 PMID:16888626 http://dx.doi.org/ 10.1038/sj.emboj.7601258
-
(2006)
EMBO J
, vol.25
, pp. 3813-3822
-
-
McGrail, J.C.1
Tatum, E.M.2
O0keefe, R.T.3
-
44
-
-
0025857390
-
Mutations in yeast U5 snRNA alter the specificity of 50 splice-site cleavage
-
PMID:2013092
-
Newman A, Norman C. Mutations in yeast U5 snRNA alter the specificity of 50 splice-site cleavage. Cell 1991 65:115-23 PMID:2013092 http://dx.doi.org/ 10.1016/0092-8674(91)90413-S
-
(1991)
Cell
, vol.65
, pp. 115-123
-
-
Newman, A.1
Norman, C.2
-
45
-
-
0026605043
-
U5 snRNA interacts with exon sequences at 50 and 30 splice sites
-
PMID:1739979
-
Newman AJ, Norman C. U5 snRNA interacts with exon sequences at 50 and 30 splice sites. Cell 1992 68:743-54 PMID:1739979 http://dx.doi.org/ 10.1016/0092-8674(92)90149-7
-
(1992)
Cell
, vol.68
, pp. 743-754
-
-
Newman, A.J.1
Norman, C.2
-
46
-
-
0032518905
-
Functional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre-mRNA splicing
-
PMID:9430647
-
O’Keefe RT, Newman AJ. Functional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre-mRNA splicing. EMBO J 1998 17:565-74 PMID:9430647 http://dx.doi.org/10.1093/emboj/ 17.2.565
-
(1998)
EMBO J
, vol.17
, pp. 565-574
-
-
O’keefe, R.T.1
Newman, A.J.2
-
47
-
-
0030598839
-
The invariant U5 snRNA loop 1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast
-
PMID:8752221
-
O’Keefe RT, Norman C, Newman AJ. The invariant U5 snRNA loop 1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast. Cell 1996 86:679-89 PMID:8752221 http://dx.doi.org/ 10.1016/S0092-8674(00)80140-3
-
(1996)
Cell
, vol.86
, pp. 679-689
-
-
O’keefe, R.T.1
Norman, C.2
Newman, A.J.3
-
48
-
-
44949117567
-
A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release
-
PMID:18570877
-
Schwer B. A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol Cell 2008 30:743-54 PMID:18570877 http://dx.doi.org/10.1016/j.molcel.2008.05.003
-
(2008)
Mol Cell
, vol.30
, pp. 743-754
-
-
Schwer, B.1
-
49
-
-
84878222925
-
Rapid screening of yeast mutants with reporters identifies new splicing phenotypes
-
PMID:23560879
-
Dreumont N, Seraphin B. Rapid screening of yeast mutants with reporters identifies new splicing phenotypes. FEBS J 2013 280:2712-26 PMID:23560879 http://dx.doi.org/10.1111/febs.12277
-
(2013)
FEBS J
, vol.280
, pp. 2712-2726
-
-
Dreumont, N.1
Seraphin, B.2
-
50
-
-
11244276986
-
Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing
-
PMID:15565172
-
Dziembowski A, Ventura AP, Rutz B, Caspary F, Faux C, Halgand F, Laprevote O, Seraphin B. Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing. EMBO J 2004 23:4847-56 PMID:15565172 http://dx.doi.org/ 10.1038/sj.emboj.7600482
-
(2004)
EMBO J
, vol.23
, pp. 4847-4856
-
-
Dziembowski, A.1
Ventura, A.P.2
Rutz, B.3
Caspary, F.4
Faux, C.5
Halgand, F.6
Laprevote, O.7
Seraphin, B.8
-
51
-
-
33745608077
-
A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention
-
PMID:16738408
-
Scherrer FW, Jr., Spingola M. A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention. RNA 2006 12:1361-72 PMID:16738408 http://dx.doi.org/10.1261/rna.2276806
-
(2006)
RNA
, vol.12
, pp. 1361-1372
-
-
Scherrer, F.W.1
Spingola, M.2
-
52
-
-
0036118353
-
Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel premRNA splicing factors, and snRNAs
-
PMID:11884590
-
Ohi MD, Link AJ, Ren LP, Jennings JL, McDonald WH, Gould KL. Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel premRNA splicing factors, and snRNAs. Mol Cell Biol 2002 22:2011-24 PMID:11884590 http://dx.doi. org/10.1128/MCB.22.7.2011-2024.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2011-2024
-
-
Ohi, M.D.1
Link, A.J.2
Ren, L.P.3
Jennings, J.L.4
McDonald, W.H.5
Gould, K.L.6
-
53
-
-
33746950475
-
Yeast ntr1/spp382 mediates prp43 function in postspliceosomes
-
PMID:16880513
-
Boon KL, Auchynnikava T, Edwalds-Gilbert G, Barrass JD, Droop AP, Dez C, Beggs JD. Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol 2006 26:6016-23 PMID:16880513 http://dx. doi.org/10.1128/MCB.02347-05
-
(2006)
Mol Cell Biol
, vol.26
, pp. 6016-6023
-
-
Boon, K.L.1
Auchynnikava, T.2
Edwalds-Gilbert, G.3
Barrass, J.D.4
Droop, A.P.5
Dez, C.6
Beggs, J.D.7
-
54
-
-
29144515824
-
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2
-
PMID:16357217
-
Tsai RT, Fu RH, Yeh FL, Tseng CK, Lin YC, Huang YH, Cheng SC. Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev 2005 19:2991-3003 PMID:16357217 http://dx.doi.org/10.1101/gad.1377405
-
(2005)
Genes Dev
, vol.19
, pp. 2991-3003
-
-
Tsai, R.T.1
Fu, R.H.2
Yeh, F.L.3
Tseng, C.K.4
Lin, Y.C.5
Huang, Y.H.6
Cheng, S.C.7
-
55
-
-
34548842257
-
Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome
-
PMID:17875666
-
Tanaka N, Aronova A, Schwer B. Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome. Genes Dev 2007 21:2312-25 PMID:17875666 http://dx.doi.org/10.1101/ gad.1580507
-
(2007)
Genes Dev
, vol.21
, pp. 2312-2325
-
-
Tanaka, N.1
Aronova, A.2
Schwer, B.3
-
56
-
-
77955972016
-
Brr2p RNA helicase with a split personality: Insights into structure and function
-
PMID:20659012
-
Hahn D, Beggs JD. Brr2p RNA helicase with a split personality: insights into structure and function. Biochem Soc Trans 2010 38:1105-9 PMID:20659012 http://dx.doi.org/10.1042/BST0381105
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1105-1109
-
-
Hahn, D.1
Beggs, J.D.2
-
57
-
-
0033056712
-
The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex
-
PMID:10411139
-
Kim DH, Rossi JJ. The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. RNA 1999 5:959-71 PMID:10411139 http://dx.doi.org/10.1017/ S135583829999012X
-
(1999)
RNA
, vol.5
, pp. 959-971
-
-
Kim, D.H.1
Rossi, J.J.2
-
58
-
-
0032537739
-
RNA unwinding in U4/ U6 snRNPs requires ATP hydrolysis and the DEIHbox splicing factor Brr2
-
PMID:9705931
-
Raghunathan PL, Guthrie C. RNA unwinding in U4/ U6 snRNPs requires ATP hydrolysis and the DEIHbox splicing factor Brr2. Curr Biol 1998 8:847-55 PMID:9705931 http://dx.doi.org/10.1016/S0960- 9822(07)00345-4
-
(1998)
Curr Biol
, vol.8
, pp. 847-855
-
-
Raghunathan, P.L.1
Guthrie, C.2
-
59
-
-
33746441457
-
The EFG- like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase
-
PMID:16885028
-
Small EC, Leggett SR, Winans AA, Staley JP. The EFG- like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell 2006 23:389-99 PMID:16885028 http://dx.doi. org/10.1016/j.molcel.2006.05.043
-
(2006)
Mol Cell
, vol.23
, pp. 389-399
-
-
Small, E.C.1
Leggett, S.R.2
Winans, A.A.3
Staley, J.P.4
-
60
-
-
45249105108
-
The role of Snu114p during pre-mRNA splicing
-
PMID:18482006
-
Frazer LN, Nancollis V, O’Keefe RT. The role of Snu114p during pre-mRNA splicing. Biochem Soc Trans 2008 36:551-3 PMID:18482006 http://dx. doi.org/10.1042/BST0360551
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 551-553
-
-
Frazer, L.N.1
Nancollis, V.2
O’keefe, R.T.3
-
61
-
-
84871880170
-
The interaction of Prp2 with a defined region of the intron is required for the first splicing reaction
-
PMID:23071087
-
Liu HL, Cheng SC. The interaction of Prp2 with a defined region of the intron is required for the first splicing reaction. Mol Cell Biol 2012 32:5056-66 PMID:23071087 http://dx.doi.org/10.1128/MCB. 01109-12
-
(2012)
Mol Cell Biol
, vol.32
, pp. 5056-5066
-
-
Liu, H.L.1
Cheng, S.C.2
-
62
-
-
0035053295
-
Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
-
PMID:11290703
-
van Nues RW, Beggs JD. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 2001 157:1451-67 PMID:11290703
-
(2001)
Genetics
, vol.157
, pp. 1451-1467
-
-
Van Nues, R.W.1
Beggs, J.D.2
-
63
-
-
36849009618
-
Dynamic interactions of Ntr1- Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly
-
PMID:17893323
-
Tsai RT, Tseng CK, Lee PJ, Chen HC, Fu RH, Chang KJ, Yeh FL, Cheng SC. Dynamic interactions of Ntr1- Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly. Mol Cell Biol 2007 27:8027-37 PMID:17893323 http://dx. doi.org/10.1128/MCB.01213-07
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8027-8037
-
-
Tsai, R.T.1
Tseng, C.K.2
Lee, P.J.3
Chen, H.C.4
Fu, R.H.5
Chang, K.J.6
Yeh, F.L.7
Cheng, S.C.8
-
64
-
-
84873041707
-
Link of NTR-mediated spliceosome disassembly with DEAH-box ATPases Prp2, Prp16, and Prp22
-
PMID:23166295
-
Chen HC, Tseng CK, Tsai RT, Chung CS, Cheng SC. Link of NTR-mediated spliceosome disassembly with DEAH-box ATPases Prp2, Prp16, and Prp22. Mol Cell Biol 2013 33:514-25 PMID:23166295 http:// dx.doi.org/10.1128/MCB.01093-12
-
(2013)
Mol Cell Biol
, vol.33
, pp. 514-525
-
-
Chen, H.C.1
Tseng, C.K.2
Tsai, R.T.3
Chung, C.S.4
Cheng, S.C.5
-
65
-
-
0037068447
-
Comprehensive proteomic analysis of the human spliceosome
-
PMID:12226669
-
Zhou Z, Licklider LJ, Gygi SP, Reed R. Comprehensive proteomic analysis of the human spliceosome. Nature 2002 419:182-5 PMID:12226669 http://dx.doi.org/ 10.1038/nature01031
-
(2002)
Nature
, vol.419
, pp. 182-185
-
-
Zhou, Z.1
Licklider, L.J.2
Gygi, S.P.3
Reed, R.4
|