Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 16, 2015, Pages E2030-E2038

  Grasset, Emilie K ^a   Duhlin, Amanda ^a   Agardh, Hanna E ^b   Ovchinnikova, Olga ^b   Hägglöf, Thomas ^a   Forsell, Mattias N ^a   Paulsson Berne, Gabrielle ^b   Hansson, Göran K ^b   Ketelhuth, Daniel F J ^b   Karlsson, Mikael C I ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Atherosclerosis; B cells; Inflammasome

Indexed keywords

CHOLESTEROL; EPITOPE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 1BETA CONVERTING ENZYME; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FLOW CYTOMETRY; GERMINAL CENTER; HISTOPATHOLOGY; HYPERLIPIDEMIA; IMMUNOGLOBULIN PRODUCING CELL; IN VITRO STUDY; INFLAMMATION; LIPID STORAGE; LIPID TRANSPORT; MOUSE; NONHUMAN; OXIDATION; PHAGOCYTE; POPULATION DYNAMICS; PRIORITY JOURNAL; SPLEEN CELL; SPLEEN INFLAMMATION; AGING; ANIMAL; C57BL MOUSE; CELL CLONE; DEFICIENCY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; SPLEEN;

MUS;

AGING; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; B-LYMPHOCYTES; CHOLESTEROL; CLONE CELLS; EPITOPES; GERMINAL CENTER; INFLAMMASOMES; INFLAMMATION; LIPOPROTEINS, LDL; LYMPHOCYTE ACTIVATION; MICE, INBRED C57BL; OXIDATION-REDUCTION; PHOSPHATIDYLCHOLINES; SPLEEN;

EID: 84928250306     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421227112     Document Type: Article

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