메뉴 건너뛰기




Volumn 207, Issue 7, 2010, Pages 1541-1554

Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency

(34)  Walter, Jolan E a   Rucci, Francesca a   Patrizi, Laura a   Recher, Mike a   Regenass, Stephan c   Paganini, Tiziana d   Keszei, Marton b   Pessach, Itai a   Lang, Philipp A e   Poliani, Pietro Luigi d   Giliani, Silvia d   Al Herz, Waleed f   Cowan, Morton J g   Puck, Jennifer M g   Bleesing, Jack h   Niehues, Tim i   Schuetz, Catharina j   Malech, Harry k   DeRavin, Suk See k   Facchetti, Fabio d   more..


Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; FICOLL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; KEYHOLE LIMPET HEMOCYANIN; RAG1 PROTEIN; TRINITROPHENYL;

EID: 77954408510     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091927     Document Type: Article
Times cited : (87)

References (77)
  • 1
    • 0033579933 scopus 로고    scopus 로고
    • Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population
    • doi:10.1084/jem.189.2.319
    • Agenès, F., and A.A. Freitas. 1999. Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population. J. Exp. Med. 189:319-330. doi:10.1084/jem.189.2.319
    • (1999) J. Exp. Med. , vol.189 , pp. 319-330
    • Agenès, F.1    Freitas, A.A.2
  • 2
    • 0041646843 scopus 로고
    • Joining of immunoglobulin heavy chain gene segments: Implications from a chromosome with evidence of three D-JH fusions
    • doi:10.1073/pnas.79.13.4118
    • Alt, F.W., and D. Baltimore. 1982. Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions. Proc. Natl. Acad. Sci. USA. 79:4118-4122. doi:10.1073/pnas.79.13.4118
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 4118-4122
    • Alt, F.W.1    Baltimore, D.2
  • 4
    • 0037114168 scopus 로고    scopus 로고
    • Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit
    • Cabatingan, M.S., M.R. Schmidt, R. Sen, and R.T. Woodland. 2002. Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit. J. Immunol. 169:6795-6805.
    • (2002) J. Immunol. , vol.169 , pp. 6795-6805
    • Cabatingan, M.S.1    Schmidt, M.R.2    Sen, R.3    Woodland, R.T.4
  • 5
    • 33750964016 scopus 로고    scopus 로고
    • B cell depletion therapy in systemic lupus erythematosus: Effect on autoantibody and antimicrobial antibody profiles
    • doi:10.1002/art.22211
    • Cambridge, G., M.J. Leandro, M. Teodorescu, J. Manson, A. Rahman, D.A. Isenberg, and J.C. Edwards. 2006. B cell depletion therapy in systemic lupus erythematosus: effect on autoantibody and antimicrobial antibody profiles. Arthritis Rheum. 54:3612-3622. doi:10.1002/art.22211
    • (2006) Arthritis Rheum. , vol.54 , pp. 3612-3622
    • Cambridge, G.1    Leandro, M.J.2    Teodorescu, M.3    Manson, J.4    Rahman, A.5    Isenberg, D.A.6    Edwards, J.C.7
  • 6
    • 67650507029 scopus 로고    scopus 로고
    • Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction
    • doi:10.1084/jem.20090547
    • Cao, W., L. Bover, M. Cho, X. Wen, S. Hanabuchi, M. Bao, D.B. Rosen, Y.H. Wang, J.L. Shaw, Q. Du, et al. 2009. Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. J. Exp. Med. 206:1603-1614. doi:10.1084/jem.20090547
    • (2009) J. Exp. Med. , vol.206 , pp. 1603-1614
    • Cao, W.1    Bover, L.2    Cho, M.3    Wen, X.4    Hanabuchi, S.5    Bao, M.6    Rosen, D.B.7    Wang, Y.H.8    Shaw, J.L.9    Du, Q.10
  • 7
    • 51049121544 scopus 로고    scopus 로고
    • Repertoire-based selection into the marginal zone compartment during B cell development
    • doi:10.1084/jem.20080559
    • Carey, J.B., C.S. Moffatt-Blue, L.C. Watson, A.L. Gavin, and A.J. Feeney. 2008. Repertoire-based selection into the marginal zone compartment during B cell development. J. Exp. Med. 205:2043-2052. doi:10.1084/jem.20080559
    • (2008) J. Exp. Med. , vol.205 , pp. 2043-2052
    • Carey, J.B.1    Moffatt-Blue, C.S.2    Watson, L.C.3    Gavin, A.L.4    Feeney, A.J.5
  • 8
    • 0034995180 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21
    • doi:10.1016/S1074-7613(01)00135-2
    • Cariappa, A., M. Tang, C. Parng, E. Nebelitskiy, M. Carroll, K. Georgopoulos, and S. Pillai. 2001. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity. 14:603-615. doi:10.1016/S1074-7613(01)00135-2
    • (2001) Immunity , vol.14 , pp. 603-615
    • Cariappa, A.1    Tang, M.2    Parng, C.3    Nebelitskiy, E.4    Carroll, M.5    Georgopoulos, K.6    Pillai, S.7
  • 9
    • 34548491824 scopus 로고    scopus 로고
    • Tolerance and Autoimmunity: Lessons at the Bedside of Primary Immunodeficiencies
    • DOI 10.1016/S0065-2776(07)95002-6, PII S0065277607950026
    • Carneiro-Sampaio, M., and A. Coutinho. 2007. Tolerance and autoimmunity: lessons at the bedside of primary immunodeficiencies. Adv. Immunol. 95:51-82. doi:10.1016/S0065-2776(07)95002-6 (Pubitemid 47380503)
    • (2007) Advances in Immunology , vol.95 , pp. 51-82
    • Carneiro-Sampaio, M.1    Coutinho, A.2
  • 16
    • 34247617742 scopus 로고    scopus 로고
    • Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells
    • Darce, J.R., B.K. Arendt, S.K. Chang, and D.F. Jelinek. 2007a. Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells. J. Immunol. 178:5612-5622.
    • (2007) J. Immunol. , vol.178 , pp. 5612-5622
    • Darce, J.R.1    Arendt, B.K.2    Chang, S.K.3    Jelinek, D.F.4
  • 17
    • 38849104447 scopus 로고    scopus 로고
    • Regulated expression of BAFF-binding receptors during human B cell differentiation
    • Darce, J.R., B.K. Arendt, X. Wu, and D.F. Jelinek. 2007b. Regulated expression of BAFF-binding receptors during human B cell differentiation. J. Immunol. 179:7276-7286.
    • (2007) J. Immunol. , vol.179 , pp. 7276-7286
    • Darce, J.R.1    Arendt, B.K.2    Wu, X.3    Jelinek, D.F.4
  • 19
    • 0021274530 scopus 로고
    • Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes
    • Durdik, J., M.W. Moore, and E. Selsing. 1984. Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes. Nature. 307:749-752. doi:10.1038/307749a0 (Pubitemid 14133949)
    • (1984) Nature , vol.307 , Issue.5953 , pp. 749-752
    • Durdik, J.1    Moore, M.W.2    Selsing, E.3
  • 21
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., T. Saunders, S. Camper, and M. Weigert. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177:999-1008. doi:10.1084/jem.177.4.999 (Pubitemid 23097389)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.4 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 24
    • 2942652985 scopus 로고    scopus 로고
    • Receptor editing is the main mechanism of B cell tolerance toward membrane antigens
    • doi:10.1038/ni1076
    • Halverson, R., R.M. Torres, and R. Pelanda. 2004. Receptor editing is the main mechanism of B cell tolerance toward membrane antigens. Nat. Immunol. 5:645-650. doi:10.1038/ni1076
    • (2004) Nat. Immunol. , vol.5 , pp. 645-650
    • Halverson, R.1    Torres, R.M.2    Pelanda, R.3
  • 25
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • doi:10.1084/jem.173.5.1213
    • Hardy, R.R., C.E. Carmack, S.A. Shinton, J.D. Kemp, and K. Hayakawa. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213-1225. doi:10.1084/jem.173.5.1213
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 27
    • 4644241216 scopus 로고    scopus 로고
    • CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10
    • He, B., X. Qiao, and A. Cerutti. 2004. CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. J. Immunol. 173:4479-4491. (Pubitemid 39280678)
    • (2004) Journal of Immunology , vol.173 , Issue.7 , pp. 4479-4491
    • He, B.1    Qiao, X.2    Cerutti, A.3
  • 29
    • 0037097665 scopus 로고    scopus 로고
    • Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
    • Hsu, B.L., S.M. Harless, R.C. Lindsley, D.M. Hilbert, and M.P. Cancro. 2002. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J. Immunol. 168:5993-5996.
    • (2002) J. Immunol. , vol.168 , pp. 5993-5996
    • Hsu, B.L.1    Harless, S.M.2    Lindsley, R.C.3    Hilbert, D.M.4    Cancro, M.P.5
  • 30
    • 0023942923 scopus 로고
    • Inhibition of self-binding antibodies (autobodies) by a VH-derived peptide
    • doi:10.1126/science.3368787
    • Kang, C.Y., T.K. Brunck, T. Kieber-Emmons, J.E. Blalock, and H. Kohler. 1988. Inhibition of self-binding antibodies (autobodies) by a VH-derived peptide. Science. 240:1034-1036. doi:10.1126/science.3368787
    • (1988) Science , vol.240 , pp. 1034-1036
    • Kang, C.Y.1    Brunck, T.K.2    Kieber-Emmons, T.3    Blalock, J.E.4    Kohler, H.5
  • 33
    • 34247613820 scopus 로고    scopus 로고
    • Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: Insights into a new regulating system of BAFF production
    • doi:10.1136/ard.2006.060772
    • Lavie, F., C. Miceli-Richard, M. Ittah, J. Sellam, J.E. Gottenberg, and X. Mariette. 2007. Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production. Ann. Rheum. Dis. 66:700-703. doi:10.1136/ard.2006.060772
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 700-703
    • Lavie, F.1    Miceli-Richard, C.2    Ittah, M.3    Sellam, J.4    Gottenberg, J.E.5    Mariette, X.6
  • 34
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
    • doi:10.1016/S1074-7613(04)00079-2
    • Lesley, R., Y. Xu, S.L. Kalled, D.M. Hess, S.R. Schwab, H.B. Shu, and J.G. Cyster. 2004. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity. 20:441-453. doi:10.1016/S1074-7613(04) 00079-2
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1    Xu, Y.2    Kalled, S.L.3    Hess, D.M.4    Schwab, S.R.5    Shu, H.B.6    Cyster, J.G.7
  • 36
    • 46249103136 scopus 로고    scopus 로고
    • Unravelling the association of partial T-cell immunodeficiency and immune dysregulation
    • doi:10.1038/nri2336
    • Liston, A., A. Enders, and O.M. Siggs. 2008. Unravelling the association of partial T-cell immunodeficiency and immune dysregulation. Nat. Rev. Immunol. 8:545-558. doi:10.1038/nri2336
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 545-558
    • Liston, A.1    Enders, A.2    Siggs, O.M.3
  • 37
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • doi:10.1084/jem.190.11.1697
    • Mackay, F., S.A. Woodcock, P. Lawton, C. Ambrose, M. Baetscher, P. Schneider, J. Tschopp, and J.L. Browning. 1999. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190:1697-1710. doi:10.1084/jem.190.11.1697
    • (1999) J. Exp. Med. , vol.190 , pp. 1697-1710
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3    Ambrose, C.4    Baetscher, M.5    Schneider, P.6    Tschopp, J.7    Browning, J.L.8
  • 39
    • 42249095669 scopus 로고    scopus 로고
    • Systemic autoimmunity in BAFF-R-mutant A/WySnJ strain mice
    • doi:10.1002/eji.200737817
    • Mayne, C.G., I.J. Amanna, F.E. Nashold, and C.E. Hayes. 2008. Systemic autoimmunity in BAFF-R-mutant A/WySnJ strain mice. Eur. J. Immunol. 38:587-598. doi:10.1002/eji.200737817
    • (2008) Eur. J. Immunol. , vol.38 , pp. 587-598
    • Mayne, C.G.1    Amanna, I.J.2    Nashold, F.E.3    Hayes, C.E.4
  • 40
    • 33845465170 scopus 로고    scopus 로고
    • Anergic B cells caught in the act
    • doi:10.1016/j.immuni.2006.11.003
    • Melchers, F. 2006. Anergic B cells caught in the act. Immunity. 25:864-867. doi:10.1016/j.immuni.2006.11.003
    • (2006) Immunity , vol.25 , pp. 864-867
    • Melchers, F.1
  • 42
    • 38749090153 scopus 로고    scopus 로고
    • Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
    • doi:10.1084/jem.20071088
    • Meyer-Bahlburg, A., S.F. Andrews, K.O. Yu, S.A. Porcelli, and D.J. Rawlings. 2008. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J. Exp. Med. 205:155-168. doi:10.1084/jem.20071088
    • (2008) J. Exp. Med. , vol.205 , pp. 155-168
    • Meyer-Bahlburg, A.1    Andrews, S.F.2    Yu, K.O.3    Porcelli, S.A.4    Rawlings, D.J.5
  • 43
    • 33646891951 scopus 로고    scopus 로고
    • Space, selection, and surveillance: Setting boundaries with BLyS
    • Miller, J.P., J.E. Stadanlick, and M.P. Cancro. 2006. Space, selection, and surveillance: setting boundaries with BLyS. J. Immunol. 176:6405-6410.
    • (2006) J. Immunol. , vol.176 , pp. 6405-6410
    • Miller, J.P.1    Stadanlick, J.E.2    Cancro, M.P.3
  • 44
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnuclesomes
    • Mohan, C., E. Alas, L. Morel, P. Yang, and E.K. Wakeland. 1998. Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J. Clin. Invest. 101:1362-1372. (Pubitemid 28145253)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.6 , pp. 1362-1372
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 45
    • 70349658717 scopus 로고    scopus 로고
    • BAFF: A local and systemic target in autoimmune diseases
    • doi:10.1111/j.1365-2249.2009.04007.x
    • Moisini, I., and A. Davidson. 2009. BAFF: a local and systemic target in autoimmune diseases. Clin. Exp. Immunol. 158:155-163. doi:10.1111/j.1365-2249. 2009.04007.x
    • (2009) Clin. Exp. Immunol. , vol.158 , pp. 155-163
    • Moisini, I.1    Davidson, A.2
  • 46
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • doi:10.1016/S0092-8674(00)00078-7
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:553-563. doi:10.1016/S0092-8674(00)00078-7
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 49
    • 0016280075 scopus 로고
    • Combined immunodeficiency and reticuloendotheliosis with eosinophilia
    • doi:10.1016/S0022-3476(74)80445-2
    • Ochs, H.D., S.D. Davis, E. Mickelson, K.G. Lerner, and R.J. Wedgwood. 1974. Combined immunodeficiency and reticuloendotheliosis with eosinophilia. J. Pediatr. 85:463-465. doi:10.1016/S0022-3476(74)80445-2
    • (1974) J. Pediatr. , vol.85 , pp. 463-465
    • Ochs, H.D.1    Davis, S.D.2    Mickelson, E.3    Lerner, K.G.4    Wedgwood, R.J.5
  • 50
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M.A., D.G. Schatz, C. Gorka, and D. Baltimore. 1990. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 248:1517-1523. doi:10.1126/science.2360047 (Pubitemid 120031576)
    • (1990) Science , vol.248 , Issue.4962 , pp. 1517-1523
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 51
    • 59649105484 scopus 로고    scopus 로고
    • RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes
    • doi:10.1084/jem.20082053
    • Panigrahi, A.K., N.G. Goodman, R.A. Eisenberg, M.R. Rickels, A. Naji, and E.T. Luning Prak. 2008. RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes. J. Exp. Med. 205:2985-2994. doi:10.1084/jem.20082053
    • (2008) J. Exp. Med. , vol.205 , pp. 2985-2994
    • Panigrahi, A.K.1    Goodman, N.G.2    Eisenberg, R.A.3    Rickels, M.R.4    Naji, A.5    Luning Prak, E.T.6
  • 52
    • 68049116664 scopus 로고    scopus 로고
    • Recent advances in primary immunodeficiencies: Identification of novel genetic defects and unanticipated phenotypes
    • doi:10.1203/PDR.0b013e31819dbe1e
    • Pessach, I., J. Walter, and L.D. Notarangelo. 2009. Recent advances in primary immunodeficiencies: identification of novel genetic defects and unanticipated phenotypes. Pediatr. Res. 65:3R-12R. doi:10.1203/PDR. 0b013e31819dbe1e
    • (2009) Pediatr. Res. , vol.65
    • Pessach, I.1    Walter, J.2    Notarangelo, L.D.3
  • 53
    • 0942279505 scopus 로고    scopus 로고
    • Positive selection and lineage commitment during peripheral B-lymphocyte development
    • doi:10.1111/j.0105-2896.2003.097.x
    • Pillai, S., A. Cariappa, and S.T. Moran. 2004. Positive selection and lineage commitment during peripheral B-lymphocyte development. Immunol. Rev. 197:206-218. doi:10.1111/j.0105-2896.2003.097.x
    • (2004) Immunol. Rev. , vol.197 , pp. 206-218
    • Pillai, S.1    Cariappa, A.2    Moran, S.T.3
  • 54
    • 67651071559 scopus 로고    scopus 로고
    • Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: Possible implications for the pathophysiology of Omenn syndrome
    • doi:10.1182/blood-2009-03-211029
    • Poliani, P.L., F. Facchetti, M. Ravanini, A.R. Gennery, A. Villa, C.M. Roifman, and L.D. Notarangelo. 2009. Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome. Blood. 114:105-108. doi:10.1182/blood-2009-03-211029
    • (2009) Blood , vol.114 , pp. 105-108
    • Poliani, P.L.1    Facchetti, F.2    Ravanini, M.3    Gennery, A.R.4    Villa, A.5    Roifman, C.M.6    Notarangelo, L.D.7
  • 55
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their antigen receptors
    • doi:10.1084/jem.177.4.1165
    • Radic, M.Z., J. Erikson, S. Litwin, and M. Weigert. 1993. B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177:1165-1173. doi:10.1084/jem.177.4.1165
    • (1993) J. Exp. Med. , vol.177 , pp. 1165-1173
    • Radic, M.Z.1    Erikson, J.2    Litwin, S.3    Weigert, M.4
  • 57
    • 0032487518 scopus 로고    scopus 로고
    • Receptor editing occurs frequently during normal B cell development
    • doi:10.1084/jem.188.7.1231
    • Retter, M.W., and D. Nemazee. 1998. Receptor editing occurs frequently during normal B cell development. J. Exp. Med. 188:1231-1238. doi:10.1084/jem.188.7.1231
    • (1998) J. Exp. Med. , vol.188 , pp. 1231-1238
    • Retter, M.W.1    Nemazee, D.2
  • 59
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene, RAG-1
    • doi:10.1016/0092-8674(89)90760-5
    • Schatz, D.G., M.A. Oettinger, and D. Baltimore. 1989. The V(D)J recombination activating gene, RAG-1. Cell. 59:1035-1048. doi:10.1016/0092- 8674(89)90760-5
    • (1989) Cell , vol.59 , pp. 1035-1048
    • Schatz, D.G.1    Oettinger, M.A.2    Baltimore, D.3
  • 60
    • 0011469747 scopus 로고    scopus 로고
    • Induction of TNBS colitis in mice
    • Chapter 15
    • Scheiffele, F., and I.J. Fuss. 2002. Induction of TNBS colitis in mice. Curr. Protoc. Immunol. Chapter 15:15: 19.
    • (2002) Curr. Protoc. Immunol. , vol.15 , pp. 19
    • Scheiffele, F.1    Fuss, I.J.2
  • 64
    • 33750980124 scopus 로고    scopus 로고
    • RAG-dependent primary immunodeficiencies
    • doi:10.1002/humu.20408
    • Sobacchi, C., V. Marrella, F. Rucci, P. Vezzoni, and A. Villa. 2006. RAG-dependent primary immunodeficiencies. Hum. Mutat. 27:1174-1184. doi:10.1002/humu.20408
    • (2006) Hum. Mutat. , vol.27 , pp. 1174-1184
    • Sobacchi, C.1    Marrella, V.2    Rucci, F.3    Vezzoni, P.4    Villa, A.5
  • 65
    • 44749093822 scopus 로고    scopus 로고
    • BAFF and the plasticity of peripheral B cell tolerance
    • doi:10.1016/j.coi.2008.03.015
    • Stadanlick, J.E., and M.P. Cancro. 2008. BAFF and the plasticity of peripheral B cell tolerance. Curr. Opin. Immunol. 20:158-161. doi:10.1016/j.coi.2008.03.015
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 158-161
    • Stadanlick, J.E.1    Cancro, M.P.2
  • 66
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • doi:10.1016/j.immuni.2004.05.010
    • Thien, M., T.G. Phan, S. Gardam, M. Amesbury, A. Basten, F. Mackay, and R. Brink. 2004. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity. 20:785-798. doi:10.1016/j.immuni.2004.05.010
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3    Amesbury, M.4    Basten, A.5    Mackay, F.6    Brink, R.7
  • 67
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S.L., D.M. Russell, and D. Nemazee. 1993. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177:1009-1020. doi:10.1084/jem.177.4.1009 (Pubitemid 23097390)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.4 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 68
    • 0036682980 scopus 로고    scopus 로고
    • Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination
    • doi:10.1101/gad.984502
    • Tsai, C.L., A.H. Drejer, and D.G. Schatz. 2002. Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination. Genes Dev. 16:1934-1949. doi:10.1101/gad.984502
    • (2002) Genes Dev. , vol.16 , pp. 1934-1949
    • Tsai, C.L.1    Drejer, A.H.2    Schatz, D.G.3
  • 69
    • 0030886882 scopus 로고    scopus 로고
    • Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice
    • doi:10.1073/pnas.94.20.10844
    • Tsitsikov, E.N., J.C. Gutierrez-Ramos, and R.S. Geha. 1997. Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice. Proc. Natl. Acad. Sci. USA. 94:10844-10849. doi:10.1073/pnas.94.20.10844
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10844-10849
    • Tsitsikov, E.N.1    Gutierrez-Ramos, J.C.2    Geha, R.S.3
  • 70
    • 33947216515 scopus 로고    scopus 로고
    • T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells
    • Ueda, Y., D. Liao, K. Yang, A. Patel, and G. Kelsoe. 2007. T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. J. Immunol. 178:3593-3601. (Pubitemid 46417626)
    • (2007) Journal of Immunology , vol.178 , Issue.6 , pp. 3593-3601
    • Ueda, Y.1    Liao, D.2    Yang, K.3    Patel, A.4    Kelsoe, G.5
  • 71
    • 39149143650 scopus 로고    scopus 로고
    • Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production
    • doi:10.1016/j.immuni.2007.12.011
    • Vela, J.L., D. Aït-Azzouzene, B.H. Duong, T. Ota, and D. Nemazee. 2008. Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production. Immunity. 28:161-170. doi:10.1016/j.immuni.2007.12.011
    • (2008) Immunity , vol.28 , pp. 161-170
    • Vela, J.L.1    Aït-Azzouzene, D.2    Duong, B.H.3    Ota, T.4    Nemazee, D.5
  • 73
    • 0035161258 scopus 로고    scopus 로고
    • V(D)J recombination defects in lymphocytes due to RAG mutations: Severe immunodeficiency with a spectrum of clinical presentations
    • doi:10.1182/blood.V97.1.81
    • Villa, A., C. Sobacchi, L.D. Notarangelo, F. Bozzi, M. Abinun, T.G. Abrahamsen, P.D. Arkwright, M. Baniyash, E.G. Brooks, M.E. Conley, et al. 2001. V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood. 97:81-88. doi:10.1182/blood.V97.1.81
    • (2001) Blood , vol.97 , pp. 81-88
    • Villa, A.1    Sobacchi, C.2    Notarangelo, L.D.3    Bozzi, F.4    Abinun, M.5    Abrahamsen, T.G.6    Arkwright, P.D.7    Baniyash, M.8    Brooks, E.G.9    Conley, M.E.10
  • 74
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • doi:10.1126/science.1086907
    • Wardemann, H., S. Yurasov, A. Schaefer, J.W. Young, E. Meffre, and M.C. Nussenzweig. 2003. Predominant autoantibody production by early human B cell precursors. Science. 301:1374-1377. doi:10.1126/science.1086907
    • (2003) Science , vol.301 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5    Nussenzweig, M.C.6
  • 75
    • 3242790171 scopus 로고    scopus 로고
    • Human autoantibody silencing by immunoglobulin light chains
    • doi:10.1084/jem.20040818
    • Wardemann, H., J. Hammersen, and M.C. Nussenzweig. 2004. Human autoantibody silencing by immunoglobulin light chains. J. Exp. Med. 200:191-199. doi:10.1084/jem.20040818
    • (2004) J. Exp. Med. , vol.200 , pp. 191-199
    • Wardemann, H.1    Hammersen, J.2    Nussenzweig, M.C.3
  • 77
    • 0022468296 scopus 로고
    • A rapid ELISA for measurement of antibodies to nucleic acid antigens using UV-treated polystyrene microplates
    • doi:10.1016/0022-1759(86)90390-X
    • Zouali, M., and B.D. Stollar. 1986. A rapid ELISA for measurement of antibodies to nucleic acid antigens using UV-treated polystyrene microplates. J. Immunol. Methods. 90:105-110. doi:10.1016/0022-1759(86)90390-X
    • (1986) J. Immunol. Methods. , vol.90 , pp. 105-110
    • Zouali, M.1    Stollar, B.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.