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Volumn 38, Issue , 2015, Pages 83-89

Lymphatic system: An active pathway for immune protection

Author keywords

Antigen delivery; Dendritic cell trafficking; Immune regulation; Lymph node; Lymphatic function

Indexed keywords

ANTIGEN;

EID: 84928204128     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2014.11.012     Document Type: Review
Times cited : (114)

References (80)
  • 1
    • 33747812115 scopus 로고    scopus 로고
    • Synchrony of high endothelial venules and lymphatic vessels revealed by immunization
    • Liao S., Ruddle N.H. Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. J Immunol 2006, 177:3369-3379.
    • (2006) J Immunol , vol.177 , pp. 3369-3379
    • Liao, S.1    Ruddle, N.H.2
  • 3
    • 84902963193 scopus 로고    scopus 로고
    • The role of lymph node sinus macrophages in host defense
    • Kuka M., Iannacone M. The role of lymph node sinus macrophages in host defense. Ann N Y Acad Sci 2014, 1319:38-46.
    • (2014) Ann N Y Acad Sci , vol.1319 , pp. 38-46
    • Kuka, M.1    Iannacone, M.2
  • 4
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • Randolph G.J., Angeli V., Swartz M.A. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat Rev Immunol 2005, 5:617-628.
    • (2005) Nat Rev Immunol , vol.5 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 5
    • 65349115397 scopus 로고    scopus 로고
    • Peripheral tolerance induction by lymph node stroma
    • Reynoso E.D., Lee J.W., Turley S.J. Peripheral tolerance induction by lymph node stroma. Adv Exp Med Biol 2009, 633:113-127.
    • (2009) Adv Exp Med Biol , vol.633 , pp. 113-127
    • Reynoso, E.D.1    Lee, J.W.2    Turley, S.J.3
  • 6
    • 84857556564 scopus 로고    scopus 로고
    • Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity
    • Swartz M.A., Lund A.W. Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat Rev Cancer 2012, 12:210-219.
    • (2012) Nat Rev Cancer , vol.12 , pp. 210-219
    • Swartz, M.A.1    Lund, A.W.2
  • 7
    • 33846140150 scopus 로고    scopus 로고
    • Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1
    • Gale N.W., Prevo R., Espinosa J., Ferguson D.J., Dominguez M.G., Yancopoulos G.D., et al. Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1. Mol Cell Biol 2007, 27:595-604.
    • (2007) Mol Cell Biol , vol.27 , pp. 595-604
    • Gale, N.W.1    Prevo, R.2    Espinosa, J.3    Ferguson, D.J.4    Dominguez, M.G.5    Yancopoulos, G.D.6
  • 8
    • 34948814992 scopus 로고    scopus 로고
    • Functionally specialized junctions between endothelial cells of lymphatic vessels
    • Baluk P., Fuxe J., Hashizume H., Romano T., Lashnits E., Butz S., et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med 2007, 204:2349-2362.
    • (2007) J Exp Med , vol.204 , pp. 2349-2362
    • Baluk, P.1    Fuxe, J.2    Hashizume, H.3    Romano, T.4    Lashnits, E.5    Butz, S.6
  • 10
    • 0037565445 scopus 로고    scopus 로고
    • Dendritic cell function in vivo during the steady state: a role in peripheral tolerance
    • Steinman R.M., Hawiger D., Liu K., Bonifaz L., Bonnyay D., Mahnke K., et al. Dendritic cell function in vivo during the steady state: a role in peripheral tolerance. Ann N Y Acad Sci 2003, 987:15-25.
    • (2003) Ann N Y Acad Sci , vol.987 , pp. 15-25
    • Steinman, R.M.1    Hawiger, D.2    Liu, K.3    Bonifaz, L.4    Bonnyay, D.5    Mahnke, K.6
  • 11
    • 49449102376 scopus 로고    scopus 로고
    • Monitoring cellular movement in vivo with photoconvertible fluorescence protein Kaede transgenic mice
    • Tomura M., Yoshida N., Tanaka J., Karasawa S., Miwa Y., Miyawaki A., et al. Monitoring cellular movement in vivo with photoconvertible fluorescence protein Kaede transgenic mice. Proc Natl Acad Sci U S A 2008, 105:10871-10876.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10871-10876
    • Tomura, M.1    Yoshida, N.2    Tanaka, J.3    Karasawa, S.4    Miwa, Y.5    Miyawaki, A.6
  • 13
    • 80555153996 scopus 로고    scopus 로고
    • DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling
    • Tal O., Lim H.Y., Gurevich I., Milo I., Shipony Z., Ng L.G., et al. DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling. J Exp Med 2011, 208:2141-2153.
    • (2011) J Exp Med , vol.208 , pp. 2141-2153
    • Tal, O.1    Lim, H.Y.2    Gurevich, I.3    Milo, I.4    Shipony, Z.5    Ng, L.G.6
  • 14
    • 73949156419 scopus 로고    scopus 로고
    • Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
    • Pflicke H., Sixt M. Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels. J Exp Med 2009, 206:2925-2935.
    • (2009) J Exp Med , vol.206 , pp. 2925-2935
    • Pflicke, H.1    Sixt, M.2
  • 15
    • 84865424661 scopus 로고    scopus 로고
    • Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage
    • Thomas S.N., Rutkowski J.M., Pasquier M., Kuan E.L., Alitalo K., Randolph G.J., et al. Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J Immunol 2012, 189:2181-2190.
    • (2012) J Immunol , vol.189 , pp. 2181-2190
    • Thomas, S.N.1    Rutkowski, J.M.2    Pasquier, M.3    Kuan, E.L.4    Alitalo, K.5    Randolph, G.J.6
  • 16
    • 84876791209 scopus 로고    scopus 로고
    • Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia
    • Platt A.M., Rutkowski J.M., Martel C., Kuan E.L., Ivanov S., Swartz M.A., et al. Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia. J Immunol 2013, 190:4608-4620.
    • (2013) J Immunol , vol.190 , pp. 4608-4620
    • Platt, A.M.1    Rutkowski, J.M.2    Martel, C.3    Kuan, E.L.4    Ivanov, S.5    Swartz, M.A.6
  • 17
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • Debes G.F., Arnold C.N., Young A.J., Krautwald S., Lipp M., Hay J.B., et al. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat Immunol 2005, 6:889-894.
    • (2005) Nat Immunol , vol.6 , pp. 889-894
    • Debes, G.F.1    Arnold, C.N.2    Young, A.J.3    Krautwald, S.4    Lipp, M.5    Hay, J.B.6
  • 18
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics
    • Bromley S.K., Thomas S.Y., Luster A.D. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol 2005, 6:895-901.
    • (2005) Nat Immunol , vol.6 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 19
    • 79251559088 scopus 로고    scopus 로고
    • CCR7 is involved in the migration of neutrophils to lymph nodes
    • Beauvillain C., Cunin P., Doni A., Scotet M., Jaillon S., Loiry M.L., et al. CCR7 is involved in the migration of neutrophils to lymph nodes. Blood 2011, 117:1196-1204.
    • (2011) Blood , vol.117 , pp. 1196-1204
    • Beauvillain, C.1    Cunin, P.2    Doni, A.3    Scotet, M.4    Jaillon, S.5    Loiry, M.L.6
  • 20
    • 84905987693 scopus 로고    scopus 로고
    • Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes
    • Gorlino C.V., Ranocchia R.P., Harman M.F., Garcia I.A., Crespo M.I., Moron G., et al. Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes. J Immunol 2014, 193:1966-1974.
    • (2014) J Immunol , vol.193 , pp. 1966-1974
    • Gorlino, C.V.1    Ranocchia, R.P.2    Harman, M.F.3    Garcia, I.A.4    Crespo, M.I.5    Moron, G.6
  • 21
    • 23944508045 scopus 로고    scopus 로고
    • Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes
    • Abadie V., Badell E., Douillard P., Ensergueix D., Leenen P.J., Tanguy M., et al. Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes. Blood 2005, 106:1843-1850.
    • (2005) Blood , vol.106 , pp. 1843-1850
    • Abadie, V.1    Badell, E.2    Douillard, P.3    Ensergueix, D.4    Leenen, P.J.5    Tanguy, M.6
  • 22
    • 1942438615 scopus 로고    scopus 로고
    • Lymphatic smooth muscle: the motor unit of lymph drainage
    • von der Weid P.Y., Zawieja D.C. Lymphatic smooth muscle: the motor unit of lymph drainage. Int J Biochem Cell Biol 2004, 36:1147-1153.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1147-1153
    • von der Weid, P.Y.1    Zawieja, D.C.2
  • 23
    • 84866421152 scopus 로고    scopus 로고
    • Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation
    • Nitschke M., Aebischer D., Abadier M., Haener S., Lucic M., Vigl B., et al. Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation. Blood 2012, 120:2249-2258.
    • (2012) Blood , vol.120 , pp. 2249-2258
    • Nitschke, M.1    Aebischer, D.2    Abadier, M.3    Haener, S.4    Lucic, M.5    Vigl, B.6
  • 24
    • 9244240285 scopus 로고    scopus 로고
    • Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes
    • Qu C., Edwards E.W., Tacke F., Angeli V., Llodra J., Sanchez-Schmitz G., et al. Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med 2004, 200:1231-1241.
    • (2004) J Exp Med , vol.200 , pp. 1231-1241
    • Qu, C.1    Edwards, E.W.2    Tacke, F.3    Angeli, V.4    Llodra, J.5    Sanchez-Schmitz, G.6
  • 25
    • 84883192541 scopus 로고    scopus 로고
    • Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses
    • Das S., Sarrou E., Podgrabinska S., Cassella M., Mungamuri S.K., Feirt N., et al. Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J Exp Med 2013, 210:1509-1528.
    • (2013) J Exp Med , vol.210 , pp. 1509-1528
    • Das, S.1    Sarrou, E.2    Podgrabinska, S.3    Cassella, M.4    Mungamuri, S.K.5    Feirt, N.6
  • 26
    • 0033081760 scopus 로고    scopus 로고
    • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
    • Gunn M.D., Kyuwa S., Tam C., Kakiuchi T., Matsuzawa A., Williams L.T., et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med 1999, 189:451-460.
    • (1999) J Exp Med , vol.189 , pp. 451-460
    • Gunn, M.D.1    Kyuwa, S.2    Tam, C.3    Kakiuchi, T.4    Matsuzawa, A.5    Williams, L.T.6
  • 27
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster J.G. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 2005, 23:127-159.
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 28
    • 84902662442 scopus 로고    scopus 로고
    • The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes
    • Ulvmar M.H., Werth K., Braun A., Kelay P., Hub E., Eller K., et al. The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nat Immunol 2014, 15:623-630.
    • (2014) Nat Immunol , vol.15 , pp. 623-630
    • Ulvmar, M.H.1    Werth, K.2    Braun, A.3    Kelay, P.4    Hub, E.5    Eller, K.6
  • 29
    • 80052025244 scopus 로고    scopus 로고
    • Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration
    • Braun A., Worbs T., Moschovakis G.L., Halle S., Hoffmann K., Bolter J., et al. Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration. Nat Immunol 2011, 12:879-887.
    • (2011) Nat Immunol , vol.12 , pp. 879-887
    • Braun, A.1    Worbs, T.2    Moschovakis, G.L.3    Halle, S.4    Hoffmann, K.5    Bolter, J.6
  • 30
    • 12444297666 scopus 로고    scopus 로고
    • The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
    • Sixt M., Kanazawa N., Selg M., Samson T., Roos G., Reinhardt D.P., et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 2005, 22:19-29.
    • (2005) Immunity , vol.22 , pp. 19-29
    • Sixt, M.1    Kanazawa, N.2    Selg, M.3    Samson, T.4    Roos, G.5    Reinhardt, D.P.6
  • 31
    • 12444272793 scopus 로고    scopus 로고
    • Conduit for privileged communications in the lymph node
    • Anderson A.O., Shaw S. Conduit for privileged communications in the lymph node. Immunity 2005, 22:3-5.
    • (2005) Immunity , vol.22 , pp. 3-5
    • Anderson, A.O.1    Shaw, S.2
  • 32
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4T cells and stimulate different aspects of cell-mediated immunity
    • Itano A.A., McSorley S.J., Reinhardt R.L., Ehst B.D., Ingulli E., Rudensky A.Y., et al. Distinct dendritic cell populations sequentially present antigen to CD4T cells and stimulate different aspects of cell-mediated immunity. Immunity 2003, 19:47-57.
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1    McSorley, S.J.2    Reinhardt, R.L.3    Ehst, B.D.4    Ingulli, E.5    Rudensky, A.Y.6
  • 34
    • 0034693949 scopus 로고    scopus 로고
    • Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
    • Gretz J.E., Norbury C.C., Anderson A.O., Proudfoot A.E., Shaw S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J Exp Med 2000, 192:1425-1440.
    • (2000) J Exp Med , vol.192 , pp. 1425-1440
    • Gretz, J.E.1    Norbury, C.C.2    Anderson, A.O.3    Proudfoot, A.E.4    Shaw, S.5
  • 35
    • 84866345786 scopus 로고    scopus 로고
    • A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread
    • Kastenmuller W., Torabi-Parizi P., Subramanian N., Lammermann T., Germain R.N. A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread. Cell 2012, 150:1235-1248.
    • (2012) Cell , vol.150 , pp. 1235-1248
    • Kastenmuller, W.1    Torabi-Parizi, P.2    Subramanian, N.3    Lammermann, T.4    Germain, R.N.5
  • 36
    • 84858761664 scopus 로고    scopus 로고
    • B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity
    • Moseman E.A., Iannacone M., Bosurgi L., Tonti E., Chevrier N., Tumanov A., et al. B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity 2012, 36:415-426.
    • (2012) Immunity , vol.36 , pp. 415-426
    • Moseman, E.A.1    Iannacone, M.2    Bosurgi, L.3    Tonti, E.4    Chevrier, N.5    Tumanov, A.6
  • 37
    • 67649221652 scopus 로고    scopus 로고
    • Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
    • Phan T.G., Green J.A., Gray E.E., Xu Y., Cyster J.G. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol 2009, 10:786-793.
    • (2009) Nat Immunol , vol.10 , pp. 786-793
    • Phan, T.G.1    Green, J.A.2    Gray, E.E.3    Xu, Y.4    Cyster, J.G.5
  • 38
    • 77951298265 scopus 로고    scopus 로고
    • Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes
    • Gonzalez S.F., Lukacs-Kornek V., Kuligowski M.P., Pitcher L.A., Degn S.E., Kim Y.A., et al. Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat Immunol 2010, 11:427-434.
    • (2010) Nat Immunol , vol.11 , pp. 427-434
    • Gonzalez, S.F.1    Lukacs-Kornek, V.2    Kuligowski, M.P.3    Pitcher, L.A.4    Degn, S.E.5    Kim, Y.A.6
  • 39
    • 35948935059 scopus 로고    scopus 로고
    • Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
    • Junt T., Moseman E.A., Iannacone M., Massberg S., Lang P.A., Boes M., et al. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 2007, 450:110-114.
    • (2007) Nature , vol.450 , pp. 110-114
    • Junt, T.1    Moseman, E.A.2    Iannacone, M.3    Massberg, S.4    Lang, P.A.5    Boes, M.6
  • 40
    • 84859385704 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
    • Cyster J.G., Schwab S.R. Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu Rev Immunol 2012, 30:69-94.
    • (2012) Annu Rev Immunol , vol.30 , pp. 69-94
    • Cyster, J.G.1    Schwab, S.R.2
  • 41
    • 78650542647 scopus 로고    scopus 로고
    • Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure
    • Grigorova I.L., Panteleev M., Cyster J.G. Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure. Proc Natl Acad Sci U S A 2010, 107:20447-20452.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20447-20452
    • Grigorova, I.L.1    Panteleev, M.2    Cyster, J.G.3
  • 42
    • 84896753840 scopus 로고    scopus 로고
    • Emerging roles of lymphatic endothelium in regulating adaptive immunity
    • Card C.M., Yu S.S., Swartz M.A. Emerging roles of lymphatic endothelium in regulating adaptive immunity. J Clin Investig 2014, 124:943-952.
    • (2014) J Clin Investig , vol.124 , pp. 943-952
    • Card, C.M.1    Yu, S.S.2    Swartz, M.A.3
  • 43
    • 84874273601 scopus 로고    scopus 로고
    • Lymphatic endothelial cells - key players in regulation of tolerance and immunity
    • Tewalt E.F., Cohen J.N., Rouhani S.J., Engelhard V.H. Lymphatic endothelial cells - key players in regulation of tolerance and immunity. Front Immunol 2012, 3:305.
    • (2012) Front Immunol , vol.3 , pp. 305
    • Tewalt, E.F.1    Cohen, J.N.2    Rouhani, S.J.3    Engelhard, V.H.4
  • 44
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • Cohen J.N., Guidi C.J., Tewalt E.F., Qiao H., Rouhani S.J., Ruddell A., et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med 2010, 207:681-688.
    • (2010) J Exp Med , vol.207 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3    Qiao, H.4    Rouhani, S.J.5    Ruddell, A.6
  • 45
    • 84870729573 scopus 로고    scopus 로고
    • Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8T cells
    • Tewalt E.F., Cohen J.N., Rouhani S.J., Guidi C.J., Qiao H., Fahl S.P., et al. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8T cells. Blood 2012, 120:4772-4782.
    • (2012) Blood , vol.120 , pp. 4772-4782
    • Tewalt, E.F.1    Cohen, J.N.2    Rouhani, S.J.3    Guidi, C.J.4    Qiao, H.5    Fahl, S.P.6
  • 46
    • 77951074210 scopus 로고    scopus 로고
    • Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
    • Fletcher A.L., Lukacs-Kornek V., Reynoso E.D., Pinner S.E., Bellemare-Pelletier A., Curry M.S., et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med 2010, 207:689-697.
    • (2010) J Exp Med , vol.207 , pp. 689-697
    • Fletcher, A.L.1    Lukacs-Kornek, V.2    Reynoso, E.D.3    Pinner, S.E.4    Bellemare-Pelletier, A.5    Curry, M.S.6
  • 47
    • 33846546257 scopus 로고    scopus 로고
    • Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
    • Lee J.W., Epardaud M., Sun J., Becker J.E., Cheng A.C., Yonekura A.R., et al. Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self. Nat Immunol 2007, 8:181-190.
    • (2007) Nat Immunol , vol.8 , pp. 181-190
    • Lee, J.W.1    Epardaud, M.2    Sun, J.3    Becker, J.E.4    Cheng, A.C.5    Yonekura, A.R.6
  • 48
    • 84861116064 scopus 로고    scopus 로고
    • VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics
    • Lund A.W., Duraes F.V., Hirosue S., Raghavan V.R., Nembrini C., Thomas S.N., et al. VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics. Cell Rep 2012, 1:191-199.
    • (2012) Cell Rep , vol.1 , pp. 191-199
    • Lund, A.W.1    Duraes, F.V.2    Hirosue, S.3    Raghavan, V.R.4    Nembrini, C.5    Thomas, S.N.6
  • 49
    • 84901247776 scopus 로고    scopus 로고
    • Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells
    • Hirosue S., Vokali E., Raghavan V.R., Rincon-Restrepo M., Lund A.W., Corthesy-Henrioud P., et al. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol 2014, 192:5002-5011.
    • (2014) J Immunol , vol.192 , pp. 5002-5011
    • Hirosue, S.1    Vokali, E.2    Raghavan, V.R.3    Rincon-Restrepo, M.4    Lund, A.W.5    Corthesy-Henrioud, P.6
  • 50
    • 84897491341 scopus 로고    scopus 로고
    • Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment
    • Cohen J.N., Tewalt E.F., Rouhani S.J., Buonomo E.L., Bruce A.N., Xu X., et al. Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. PLOS ONE 2014, 9:e87740.
    • (2014) PLOS ONE , vol.9 , pp. e87740
    • Cohen, J.N.1    Tewalt, E.F.2    Rouhani, S.J.3    Buonomo, E.L.4    Bruce, A.N.5    Xu, X.6
  • 51
    • 84859926294 scopus 로고    scopus 로고
    • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
    • Malhotra D., Fletcher A.L., Astarita J., Lukacs-Kornek V., Tayalia P., Gonzalez S.F., et al. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol 2012, 13:499-510.
    • (2012) Nat Immunol , vol.13 , pp. 499-510
    • Malhotra, D.1    Fletcher, A.L.2    Astarita, J.3    Lukacs-Kornek, V.4    Tayalia, P.5    Gonzalez, S.F.6
  • 52
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis molecular mechanisms and future promise
    • Tammela T., Alitalo K. Lymphangiogenesis molecular mechanisms and future promise. Cell 2010, 140:460-476.
    • (2010) Cell , vol.140 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 53
    • 24644501637 scopus 로고    scopus 로고
    • The crucial role of macrophages in lymphangiogenesis
    • Kerjaschki D. The crucial role of macrophages in lymphangiogenesis. J Clin Investig 2005, 115:2316-2319.
    • (2005) J Clin Investig , vol.115 , pp. 2316-2319
    • Kerjaschki, D.1
  • 54
    • 24644474779 scopus 로고    scopus 로고
    • Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages
    • Maruyama K., Ii M., Cursiefen C., Jackson D.G., Keino H., Tomita M., et al. Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Investig 2005, 115:2363-2372.
    • (2005) J Clin Investig , vol.115 , pp. 2363-2372
    • Maruyama, K.1    Ii, M.2    Cursiefen, C.3    Jackson, D.G.4    Keino, H.5    Tomita, M.6
  • 55
    • 78149246290 scopus 로고    scopus 로고
    • Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation
    • Gordon E.J., Rao S., Pollard J.W., Nutt S.L., Lang R.A., Harvey N.L. Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development 2010, 137:3899-3910.
    • (2010) Development , vol.137 , pp. 3899-3910
    • Gordon, E.J.1    Rao, S.2    Pollard, J.W.3    Nutt, S.L.4    Lang, R.A.5    Harvey, N.L.6
  • 56
    • 20144369085 scopus 로고    scopus 로고
    • Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
    • Baluk P., Tammela T., Ator E., Lyubynska N., Achen M.G., Hicklin D.J., et al. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Investig 2005, 115:247-257.
    • (2005) J Clin Investig , vol.115 , pp. 247-257
    • Baluk, P.1    Tammela, T.2    Ator, E.3    Lyubynska, N.4    Achen, M.G.5    Hicklin, D.J.6
  • 57
    • 39449096958 scopus 로고    scopus 로고
    • Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer
    • Jeon B.H., Jang C., Han J., Kataru R.P., Piao L., Jung K., et al. Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer. Cancer Res 2008, 68:1100-1109.
    • (2008) Cancer Res , vol.68 , pp. 1100-1109
    • Jeon, B.H.1    Jang, C.2    Han, J.3    Kataru, R.P.4    Piao, L.5    Jung, K.6
  • 58
    • 73549105244 scopus 로고    scopus 로고
    • Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm
    • Kim K.E., Koh Y.J., Jeon B.H., Jang C., Han J., Kataru R.P., et al. Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. Am J Pathol 2009, 175:1733-1745.
    • (2009) Am J Pathol , vol.175 , pp. 1733-1745
    • Kim, K.E.1    Koh, Y.J.2    Jeon, B.H.3    Jang, C.4    Han, J.5    Kataru, R.P.6
  • 59
    • 32244443955 scopus 로고    scopus 로고
    • B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization
    • Angeli V., Ginhoux F., Llodra J., Quemeneur L., Frenette P.S., Skobe M., et al. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 2006, 24:203-215.
    • (2006) Immunity , vol.24 , pp. 203-215
    • Angeli, V.1    Ginhoux, F.2    Llodra, J.3    Quemeneur, L.4    Frenette, P.S.5    Skobe, M.6
  • 60
    • 78751688024 scopus 로고    scopus 로고
    • T lymphocytes negatively regulate lymph node lymphatic vessel formation
    • Kataru R.P., Kim H., Jang C., Choi D.K., Koh B.I., Kim M., et al. T lymphocytes negatively regulate lymph node lymphatic vessel formation. Immunity 2011, 34:96-107.
    • (2011) Immunity , vol.34 , pp. 96-107
    • Kataru, R.P.1    Kim, H.2    Jang, C.3    Choi, D.K.4    Koh, B.I.5    Kim, M.6
  • 61
    • 33748075460 scopus 로고    scopus 로고
    • Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications
    • Hoshida T., Isaka N., Hagendoorn J., di Tomaso E., Chen Y.L., Pytowski B., et al. Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res 2006, 66:8065-8075.
    • (2006) Cancer Res , vol.66 , pp. 8065-8075
    • Hoshida, T.1    Isaka, N.2    Hagendoorn, J.3    di Tomaso, E.4    Chen, Y.L.5    Pytowski, B.6
  • 63
    • 84861645540 scopus 로고    scopus 로고
    • Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation
    • Yao L.C., Baluk P., Srinivasan R.S., Oliver G., McDonald D.M. Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol 2012, 180:2561-2575.
    • (2012) Am J Pathol , vol.180 , pp. 2561-2575
    • Yao, L.C.1    Baluk, P.2    Srinivasan, R.S.3    Oliver, G.4    McDonald, D.M.5
  • 65
    • 84878254278 scopus 로고    scopus 로고
    • Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis
    • Mathias R., von der Weid P.Y. Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. Am J Physiol Gastrointest Liver Physiol 2013, 304:G623-G634.
    • (2013) Am J Physiol Gastrointest Liver Physiol , vol.304 , pp. G623-G634
    • Mathias, R.1    von der Weid, P.Y.2
  • 66
    • 33846430852 scopus 로고    scopus 로고
    • The role of protective effects of proline-containing peptides (PGP, PG, and GP) in contractile dysfunction of mesenteric lymphatic vessels in rats with experimental acute peritonitis
    • Umarova B.A., Lelekova T.V., Kopylova G.N., Goncharova E.L., Bakaeva Z.V., Samonina G.E. The role of protective effects of proline-containing peptides (PGP, PG, and GP) in contractile dysfunction of mesenteric lymphatic vessels in rats with experimental acute peritonitis. Bull Exp Biol Med 2006, 142:279-282.
    • (2006) Bull Exp Biol Med , vol.142 , pp. 279-282
    • Umarova, B.A.1    Lelekova, T.V.2    Kopylova, G.N.3    Goncharova, E.L.4    Bakaeva, Z.V.5    Samonina, G.E.6
  • 67
  • 69
    • 84896055340 scopus 로고    scopus 로고
    • In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice
    • Bouta E.M., Wood R.W., Brown E.B., Rahimi H., Ritchlin C.T., Schwarz E.M. In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. J Physiol 2014, 592:1213-1223.
    • (2014) J Physiol , vol.592 , pp. 1213-1223
    • Bouta, E.M.1    Wood, R.W.2    Brown, E.B.3    Rahimi, H.4    Ritchlin, C.T.5    Schwarz, E.M.6
  • 70
    • 77954491955 scopus 로고    scopus 로고
    • B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes
    • Shrestha B., Hashiguchi T., Ito T., Miura N., Takenouchi K., Oyama Y., et al. B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes. J Immunol 2010, 184:4819-4826.
    • (2010) J Immunol , vol.184 , pp. 4819-4826
    • Shrestha, B.1    Hashiguchi, T.2    Ito, T.3    Miura, N.4    Takenouchi, K.5    Oyama, Y.6
  • 71
    • 0025200286 scopus 로고
    • The function of high endothelial venules in mouse lymph nodes stimulated by oxazolone
    • Mebius R.E., Breve J., Duijvestijn A.M., Kraal G. The function of high endothelial venules in mouse lymph nodes stimulated by oxazolone. Immunology 1990, 71:423-427.
    • (1990) Immunology , vol.71 , pp. 423-427
    • Mebius, R.E.1    Breve, J.2    Duijvestijn, A.M.3    Kraal, G.4
  • 72
    • 0026014880 scopus 로고
    • The influence of afferent lymphatic vessel interruption on vascular addressin expression
    • Mebius R.E., Streeter P.R., Breve J., Duijvestijn A.M., Kraal G. The influence of afferent lymphatic vessel interruption on vascular addressin expression. J Cell Biol 1991, 115:85-95.
    • (1991) J Cell Biol , vol.115 , pp. 85-95
    • Mebius, R.E.1    Streeter, P.R.2    Breve, J.3    Duijvestijn, A.M.4    Kraal, G.5
  • 73
    • 0027133074 scopus 로고
    • Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow
    • Mebius R.E., Dowbenko D., Williams A., Fennie C., Lasky L.A., Watson S.R. Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow. J Immunol 1993, 151:6769-6776.
    • (1993) J Immunol , vol.151 , pp. 6769-6776
    • Mebius, R.E.1    Dowbenko, D.2    Williams, A.3    Fennie, C.4    Lasky, L.A.5    Watson, S.R.6
  • 74
    • 81855203183 scopus 로고    scopus 로고
    • Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules
    • Moussion C., Girard J.P. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature 2011, 479:542-546.
    • (2011) Nature , vol.479 , pp. 542-546
    • Moussion, C.1    Girard, J.P.2
  • 76
    • 84879709783 scopus 로고    scopus 로고
    • An analysis of the function and expression of D6 on lymphatic endothelial cells
    • McKimmie C.S., Singh M.D., Hewit K., Lopez-Franco O., Le Brocq M., Rose-John S., et al. An analysis of the function and expression of D6 on lymphatic endothelial cells. Blood 2013, 121:3768-3777.
    • (2013) Blood , vol.121 , pp. 3768-3777
    • McKimmie, C.S.1    Singh, M.D.2    Hewit, K.3    Lopez-Franco, O.4    Le Brocq, M.5    Rose-John, S.6
  • 77
    • 83055179249 scopus 로고    scopus 로고
    • D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion
    • Lee K.M., McKimmie C.S., Gilchrist D.S., Pallas K.J., Nibbs R.J., Garside P., et al. D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood 2011, 118:6220-6229.
    • (2011) Blood , vol.118 , pp. 6220-6229
    • Lee, K.M.1    McKimmie, C.S.2    Gilchrist, D.S.3    Pallas, K.J.4    Nibbs, R.J.5    Garside, P.6
  • 78
    • 68149124237 scopus 로고    scopus 로고
    • Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism
    • Podgrabinska S., Kamalu O., Mayer L., Shimaoka M., Snoeck H., Randolph G.J., et al. Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol 2009, 183:1767-1779.
    • (2009) J Immunol , vol.183 , pp. 1767-1779
    • Podgrabinska, S.1    Kamalu, O.2    Mayer, L.3    Shimaoka, M.4    Snoeck, H.5    Randolph, G.J.6
  • 79
    • 84863206217 scopus 로고    scopus 로고
    • Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation
    • Norder M., Gutierrez M.G., Zicari S., Cervi E., Caruso A., Guzman C.A. Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation. FASEB J 2012, 26:2835-2846.
    • (2012) FASEB J , vol.26 , pp. 2835-2846
    • Norder, M.1    Gutierrez, M.G.2    Zicari, S.3    Cervi, E.4    Caruso, A.5    Guzman, C.A.6
  • 80
    • 80054918372 scopus 로고    scopus 로고
    • Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
    • Lukacs-Kornek V., Malhotra D., Fletcher A.L., Acton S.E., Elpek K.G., Tayalia P., et al. Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat Immunol 2011.
    • (2011) Nat Immunol
    • Lukacs-Kornek, V.1    Malhotra, D.2    Fletcher, A.L.3    Acton, S.E.4    Elpek, K.G.5    Tayalia, P.6


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