-
1
-
-
33749440219
-
Age-related macular degeneration
-
De Jong PT. Age-related macular degeneration. N Engl J Med 2006;355:1474-85.
-
(2006)
N Engl J Med
, vol.355
, pp. 1474-1485
-
-
De Jong, P.T.1
-
2
-
-
0021752680
-
Age-related macular degeneration and blindness due to neovascular maculopathy
-
Ferris FL III, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984;102:1640-2.
-
(1984)
Arch Ophthalmol
, vol.102
, pp. 1640-1642
-
-
Ferris, F.L.1
Fine, S.L.2
Hyman, L.3
-
3
-
-
11144354339
-
Prevalence of age-related macular degeneration in the United States
-
Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004;122:564-72.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Munoz, B.3
-
4
-
-
77951622411
-
The prevalence of age-related macular degeneration in Asians: A systematic review and meta-analysis
-
Kawasaki R, Yasuda M, Song SJ, et al. The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis. Ophthalmology 2010;117:921-7.
-
(2010)
Ophthalmology
, vol.117
, pp. 921-927
-
-
Kawasaki, R.1
Yasuda, M.2
Song, S.J.3
-
5
-
-
0033652453
-
Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study report number 3
-
Age-Related Eye Disease Study Research Group. Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study report number 3. Ophthalmology 2000;107:2224-32.
-
(2000)
Ophthalmology
, vol.107
, pp. 2224-2232
-
-
-
6
-
-
33846424317
-
Genetic insights into the pathobiology of age-related macular degeneration
-
Mullins RF. Genetic insights into the pathobiology of age-related macular degeneration. Int Ophthalmol Clin 2007;47:1-14.
-
(2007)
Int Ophthalmol Clin
, vol.47
, pp. 1-14
-
-
Mullins, R.F.1
-
7
-
-
70350238360
-
Unraveling a multifactorial late-onset disease: From genetic susceptibility to disease mechanisms for age-related macular degeneration
-
Swaroop A, Chew EY, Rickman CB, et al. Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet 2009;10:19-43.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 19-43
-
-
Swaroop, A.1
Chew, E.Y.2
Rickman, C.B.3
-
8
-
-
27744462212
-
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
-
Rivera A, Fisher SA, Fritsche LG, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 2005;14:3227-36.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3227-3236
-
-
Rivera, A.1
Fisher, S.A.2
Fritsche, L.G.3
-
9
-
-
75749140621
-
ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
-
Kortvely E, Hauck SM, Duetsch G, et al. ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations. Invest Ophthalmol Vis Sci 2010;51:79-88.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 79-88
-
-
Kortvely, E.1
Hauck, S.M.2
Duetsch, G.3
-
10
-
-
36049042661
-
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
-
Kanda A, Chen W, Othman M, et al. A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci USA 2007;104:16227-32.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16227-16232
-
-
Kanda, A.1
Chen, W.2
Othman, M.3
-
11
-
-
46249098503
-
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
-
Fritsche LG, Loenhardt T, Janssen A, et al. Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet 2008;40:892-6.
-
(2008)
Nat Genet
, vol.40
, pp. 892-896
-
-
Fritsche, L.G.1
Loenhardt, T.2
Janssen, A.3
-
12
-
-
33749445317
-
Ranibizumab for neovascular age-related macular degeneration
-
Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355:1419-31.
-
(2006)
N Engl J Med
, vol.355
, pp. 1419-1431
-
-
Rosenfeld, P.J.1
Brown, D.M.2
Heier, J.S.3
-
13
-
-
33749451356
-
Ranibizumab versus verteporfin for neovascular age-related macular degeneration
-
Brown DM, Kaiser PK, Michels M, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355:1432-44.
-
(2006)
N Engl J Med
, vol.355
, pp. 1432-1444
-
-
Brown, D.M.1
Kaiser, P.K.2
Michels, M.3
-
14
-
-
33644502828
-
Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration
-
Avery RL, Pieramici DJ, Rabena MD, et al. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmology 2006;113:363-72.
-
(2006)
Ophthalmology
, vol.113
, pp. 363-372
-
-
Avery, R.L.1
Pieramici, D.J.2
Rabena, M.D.3
-
15
-
-
84870723704
-
Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration
-
Heier JS, Brown DM, Chong V, et al. Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration. Ophthalmology 2012;119:2537-48.
-
(2012)
Ophthalmology
, vol.119
, pp. 2537-2548
-
-
Heier, J.S.1
Brown, D.M.2
Chong, V.3
-
16
-
-
0032871253
-
Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: Results of retreatments in a phase 1 and 2 study
-
Schmidt-Erfurth U, Miller J W, Sickenberg M, et al. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of retreatments in a phase 1 and 2 study. Arch Ophthalmol 1999;117:1177-87.
-
(1999)
Arch Ophthalmol
, vol.117
, pp. 1177-1187
-
-
Schmidt-Erfurth, U.1
Miller, J.W.2
Sickenberg, M.3
-
17
-
-
84856059368
-
CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration
-
McKibbin M, Ali M, Bansal S, et al. CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration. Br J Ophthalmol 2012;96:208-12.
-
(2012)
Br J Ophthalmol
, vol.96
, pp. 208-212
-
-
McKibbin, M.1
Ali, M.2
Bansal, S.3
-
18
-
-
44349192752
-
CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
-
Klein ML, Francis PJ, Rosner B, et al. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology 2008;115:1019-25.
-
(2008)
Ophthalmology
, vol.115
, pp. 1019-1025
-
-
Klein, M.L.1
Francis, P.J.2
Rosner, B.3
-
19
-
-
84891681426
-
Pharmacogenetic influence of LOC387715/HTRA1 on the efficacy of bevacizumab treatment for age-related macular degeneration in a Korean population
-
Kang HK, Yoon MH, Lee DH, et al. Pharmacogenetic influence of LOC387715/HTRA1 on the efficacy of bevacizumab treatment for age-related macular degeneration in a Korean population. Korean J Ophthalmol 2012;26:414-22.
-
(2012)
Korean J Ophthalmol
, vol.26
, pp. 414-422
-
-
Kang, H.K.1
Yoon, M.H.2
Lee, D.H.3
-
20
-
-
84885972660
-
VEGF gene polymorphism and response to intravitreal ranibizumab in neovascular age-related macular degeneration
-
dos Reis Veloso CE, Frota de Almeida LN, Recchia FM, et al. VEGF gene polymorphism and response to intravitreal ranibizumab in neovascular age-related macular degeneration. Ophthalmic Res 2013;51:1-8.
-
(2013)
Ophthalmic Res
, vol.51
, pp. 1-8
-
-
Dos Reis Veloso, C.E.1
Frota De Almeida, L.N.2
Recchia, F.M.3
-
21
-
-
84868194934
-
Cumulative effect of risk alleles in CFH, ARMS2, and VEGFA on the response to ranibizumab treatment in age-related macular degeneration
-
Smailhodzic D, Muether PS, Chen J, et al. Cumulative effect of risk alleles in CFH, ARMS2, and VEGFA on the response to ranibizumab treatment in age-related macular degeneration. Ophthalmology 2012;119:2304-11.
-
(2012)
Ophthalmology
, vol.119
, pp. 2304-2311
-
-
Smailhodzic, D.1
Muether, P.S.2
Chen, J.3
-
22
-
-
79958079300
-
Complement factor H Y402H gene polymorphism and response to intravitreal bevacizumab in exudative age-related macular degeneration
-
Nischler C, Oberkofler H, Ortner C, et al. Complement factor H Y402H gene polymorphism and response to intravitreal bevacizumab in exudative age-related macular degeneration. Acta Ophthalmol 2011;89:e344-49.
-
(2011)
Acta Ophthalmol
, vol.89
, pp. e344-e349
-
-
Nischler, C.1
Oberkofler, H.2
Ortner, C.3
-
23
-
-
84865049405
-
Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: A meta-analysis
-
Chen H, Yu KD, Xu GZ. Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis. PloS ONE 2012;7:e42464.
-
(2012)
PloS ONE
, vol.7
, pp. e42464
-
-
Chen, H.1
Yu, K.D.2
Xu, G.Z.3
-
24
-
-
79955596897
-
The association of age-related maculopathy susceptibility 2 polymorphisms with phenotype in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
-
Bessho H, Honda S, Kondo N, et al. The association of age-related maculopathy susceptibility 2 polymorphisms with phenotype in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. Mol Vis 2011;17:977-82.
-
(2011)
Mol Vis
, vol.17
, pp. 977-982
-
-
Bessho, H.1
Honda, S.2
Kondo, N.3
-
25
-
-
84890036850
-
Improved response to ranibizumab in ex and current smokers with age-related macular degeneration (AMD), but no evidence that CFH, ARMS2/HTRA1 Or VEGF genotypes predict treatment outcome
-
Inglehearn CF, Ali M, Gale R, et al. Improved response to ranibizumab in ex and current smokers with age-related macular degeneration (AMD), but no evidence that CFH, ARMS2/HTRA1 Or VEGF genotypes predict treatment outcome. Invest Ophthalmol Vis Sci 2012;53:3325.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 3325
-
-
Inglehearn, C.F.1
Ali, M.2
Gale, R.3
-
26
-
-
80051763854
-
Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD
-
Kloeckener-Gruissem B, Barthelmes D, Labs S, et al. Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD. Invest Ophthalmol Vis Sci 2011;52:4694-702.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 4694-4702
-
-
Kloeckener-Gruissem, B.1
Barthelmes, D.2
Labs, S.3
-
27
-
-
78650767139
-
Involvement of genetic factors in the response to a variable-dosing ranibizumab treatment regimen for age-related macular degeneration
-
Teper SJ, Nowinska A, Pilat J, et al. Involvement of genetic factors in the response to a variable-dosing ranibizumab treatment regimen for age-related macular degeneration. Mol Vis 2010;16:2598-604.
-
(2010)
Mol Vis
, vol.16
, pp. 2598-2604
-
-
Teper, S.J.1
Nowinska, A.2
Pilat, J.3
-
28
-
-
79958225412
-
Inspection of a deviation from Hardy-Weinberg equilibrium in familial breast cancer cases from a case-control study in a meta-analysis
-
Yu KD, Shao ZM. Inspection of a deviation from Hardy-Weinberg equilibrium in familial breast cancer cases from a case-control study in a meta-analysis. Breast Cancer Res Treat 2001;127:577-9.
-
(2001)
Breast Cancer Res Treat
, vol.127
, pp. 577-579
-
-
Yu, K.D.1
Shao, Z.M.2
-
29
-
-
36549016602
-
Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab
-
Brantley MA Jr, Fang AM, King JM, et al. Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab. Ophthalmology 2007;114:2168-73.
-
(2007)
Ophthalmology
, vol.114
, pp. 2168-2173
-
-
Brantley, M.A.1
Fang, A.M.2
King, J.M.3
-
30
-
-
84855170104
-
Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration
-
Orlin A, Hadley D, Chang W, et al. Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration. Retina 2012;32:4-9.
-
(2012)
Retina
, vol.32
, pp. 4-9
-
-
Orlin, A.1
Hadley, D.2
Chang, W.3
-
31
-
-
84875209738
-
Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT)
-
Hagstrom SA, Ying GS, Pauer GJ, et al. Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2013;120:593-9.
-
(2013)
Ophthalmology
, vol.120
, pp. 593-599
-
-
Hagstrom, S.A.1
Ying, G.S.2
Pauer, G.J.3
-
32
-
-
84885022545
-
Interleukin 8 promoter polymorphism predicts the initial response to bevacizumab treatment for exudative age-related macular degeneration
-
Hautamäki A, Kivioja J, Vavuli S, et al. Interleukin 8 promoter polymorphism predicts the initial response to bevacizumab treatment for exudative age-related macular degeneration. Retina 2013;33:1815-27.
-
(2013)
Retina
, vol.33
, pp. 1815-1827
-
-
Hautamäki, A.1
Kivioja, J.2
Vavuli, S.3
-
33
-
-
84885448955
-
A pharmacogenetics study to predict outcome in patients receiving anti-VEGF therapy in age related macular degeneration
-
Kitchens JW, Kassem N, Wood W, et al. A pharmacogenetics study to predict outcome in patients receiving anti-VEGF therapy in age related macular degeneration. Clin Ophthalmol 2013;7:1987-93.
-
(2013)
Clin Ophthalmol
, vol.7
, pp. 1987-1993
-
-
Kitchens, J.W.1
Kassem, N.2
Wood, W.3
-
34
-
-
84887989386
-
Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study
-
Lotery AJ, Gibson J, Cree AJ, et al. Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study. Ophthalmology 2013;120:2637-43.
-
(2013)
Ophthalmology
, vol.120
, pp. 2637-2643
-
-
Lotery, A.J.1
Gibson, J.2
Cree, A.J.3
-
35
-
-
84881183687
-
Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration
-
Abedi F, Wickremasinghe S, Richardson AJ, et al. Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration. Ophthalmology 2013;120:1641-8.
-
(2013)
Ophthalmology
, vol.120
, pp. 1641-1648
-
-
Abedi, F.1
Wickremasinghe, S.2
Richardson, A.J.3
-
36
-
-
84862760298
-
Factors associated with the response of age-related macular degeneration to intravitreal ranibizumab treatment
-
Yamashiro K, Tomita K, Tsujikawa A, et al. Factors associated with the response of age-related macular degeneration to intravitreal ranibizumab treatment. Am J Ophthalmol 2012;154:125-36.
-
(2012)
Am J Ophthalmol
, vol.154
, pp. 125-136
-
-
Yamashiro, K.1
Tomita, K.2
Tsujikawa, A.3
-
37
-
-
84884262965
-
Predictors of visual response to intravitreal bevacizumab for treatment of neovascular age-related macular degeneration
-
Fang K, Tian J, Qing X, et al. Predictors of visual response to intravitreal bevacizumab for treatment of neovascular age-related macular degeneration. J Ophthalmol 2013;2013:676049.
-
(2013)
J Ophthalmol
, vol.2013
, pp. 676049
-
-
Fang, K.1
Tian, J.2
Qing, X.3
-
38
-
-
84856614826
-
LOC387715-HTRA1 variants and the response to combined photodynamic therapy with intravitreal bevacizumab for polypoidal choroidal vasculopathy
-
Park DH, Kim IT. LOC387715-HTRA1 variants and the response to combined photodynamic therapy with intravitreal bevacizumab for polypoidal choroidal vasculopathy. Retina 2012;32:299-307.
-
(2012)
Retina
, vol.32
, pp. 299-307
-
-
Park, D.H.1
Kim, I.T.2
-
39
-
-
84901984256
-
Evaluation of clinical and genetic indicators for the early response to intravitreal ranibizumab in exudative age-related macular degeneration
-
Matsumiya W, Honda S, Yanagisawa S, et al. Evaluation of clinical and genetic indicators for the early response to intravitreal ranibizumab in exudative age-related macular degeneration. Pharmacogenomics 2014;15:833-43.
-
(2014)
Pharmacogenomics
, vol.15
, pp. 833-843
-
-
Matsumiya, W.1
Honda, S.2
Yanagisawa, S.3
-
40
-
-
84895073459
-
Genetic factors associated with response to intravitreal ranibizumab in Korean patients with neovascular age-related macular degeneration
-
Park UC, Shin JY, Kim SJ, et al. Genetic factors associated with response to intravitreal ranibizumab in Korean patients with neovascular age-related macular degeneration. Retina 2014;34:288-97.
-
(2014)
Retina
, vol.34
, pp. 288-297
-
-
Park, U.C.1
Shin, J.Y.2
Kim, S.J.3
-
41
-
-
34548749902
-
LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population
-
Kondo N, Honda S, Ishibashi K, et al. LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population. Am J Ophthalmol 2007;144:608-12.
-
(2007)
Am J Ophthalmol
, vol.144
, pp. 608-612
-
-
Kondo, N.1
Honda, S.2
Ishibashi, K.3
-
42
-
-
67349272722
-
ARMS2 (LOC387715) variants in Japanese patients with exudative age-related macular degeneration and polypoidal choroidal vasculopathy
-
Gotoh N, Nakanishi H, Hayashi H, et al. ARMS2 (LOC387715) variants in Japanese patients with exudative age-related macular degeneration and polypoidal choroidal vasculopathy. Am J Ophthalmol 2009;147:1037-41.
-
(2009)
Am J Ophthalmol
, vol.147
, pp. 1037-1041
-
-
Gotoh, N.1
Nakanishi, H.2
Hayashi, H.3
-
43
-
-
23944465880
-
Susceptibility genes for age-related maculopathy on chromosome 10q26
-
Jakobsdottir J, Conley YP, Weeks DE, et al. Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet 2005;77:389-407.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 389-407
-
-
Jakobsdottir, J.1
Conley, Y.P.2
Weeks, D.E.3
-
44
-
-
84872236150
-
Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy
-
Cheng Y, Huang L, Li X, et al. Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy. PLoS ONE 2013;8:e53665.
-
(2013)
PLoS ONE
, vol.8
, pp. e53665
-
-
Cheng, Y.1
Huang, L.2
Li, X.3
-
45
-
-
84885020335
-
The age-related maculopathy susceptibility 2 polymorphism and polypoidal choroidal vasculopathy in Asian populations: A meta-analysis
-
Yuan D, Yuan D, Yuan S, et al. The age-related maculopathy susceptibility 2 polymorphism and polypoidal choroidal vasculopathy in Asian populations: a meta-analysis. Ophthalmology 2013;120:2051-7.
-
(2013)
Ophthalmology
, vol.120
, pp. 2051-2057
-
-
Yuan, D.1
Yuan, D.2
Yuan, S.3
-
46
-
-
77951636898
-
Analysis of the indel at the ARMS2 3′UTR in age-related macular degeneration
-
Wang G, Spencer KL, Scott WK, et al. Analysis of the indel at the ARMS2 3′UTR in age-related macular degeneration. Hum Genet 2010;127:595-602.
-
(2010)
Hum Genet
, vol.127
, pp. 595-602
-
-
Wang, G.1
Spencer, K.L.2
Scott, W.K.3
|